Jun-Ichi Yamaguchi

Jun-Ichi Yamaguchi

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Jun-Ichi Yamaguchi

Jun-Ichi Yamaguchi

Publications by authors named "Jun-Ichi Yamaguchi"

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37Publications

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Preclinical disposition of MGS0274 besylate, a prodrug of a potent group II metabotropic glutamate receptor agonist MGS0008 for the treatment of schizophrenia.

Pharmacol Res Perspect 2019 10 13;7(5):e00520. Epub 2019 Sep 13.

Drug Metabolism and Pharmacokinetics Drug Safety and Pharmacokinetics Laboratories Research Headquarters Taisho Pharmaceutical Co., Ltd. Saitama Japan.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/prp2.520
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http://dx.doi.org/10.1002/prp2.520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743422PMC
October 2019

Systematic synthetic study of four diastereomerically distinct limonene-1,2-diols and their corresponding cyclic carbonates.

Beilstein J Org Chem 2019 14;15:130-136. Epub 2019 Jan 14.

Graduate School of Engineering, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki-city 852-8521, Japan.

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http://dx.doi.org/10.3762/bjoc.15.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350878PMC
January 2019

Now is the time for (2R,6R)-hydroxynorketamine to be viewed independently from its parent drug.

Pharmacol Biochem Behav 2018 12 7;175:24-26. Epub 2018 Sep 7.

Research Headquarters, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama, Saitama 331-9530, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00913057183044
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http://dx.doi.org/10.1016/j.pbb.2018.09.005DOI Listing
December 2018

Is the History Repeated? Can (2,6)-Hydroxynorketamine be Another Antidepressant?

J Exp Neurosci 2018 4;12:1179069518815445. Epub 2018 Dec 4.

Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.

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http://dx.doi.org/10.1177/1179069518815445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299292PMC
December 2018

Is the History Repeated? Can (2,6)-Hydroxynorketamine be Another Antidepressant?

J Exp Neurosci 2018 4;12:1179069518815445. Epub 2018 Dec 4.

Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.

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http://dx.doi.org/10.1177/1179069518815445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299292PMC
December 2018

Imaging Mass Microscopy of Kidneys from Azithromycin-Treated Rats with Phospholipidosis.

Am J Pathol 2018 09 6;188(9):1993-2003. Epub 2018 Jul 6.

Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama-shi, Japan.

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http://dx.doi.org/10.1016/j.ajpath.2018.05.018DOI Listing
September 2018

(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice.

Neuropsychopharmacology 2018 08 3;43(9):1900-1907. Epub 2018 May 3.

Research Headquarters, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama, Saitama, 331-9530, Japan.

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http://dx.doi.org/10.1038/s41386-018-0084-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046044PMC
August 2018

A rapid and sensitive chiral LC-MS/MS method for the determination of ketamine and norketamine in mouse plasma, brain and cerebrospinal fluid applicable to the stereoselective pharmacokinetic study of ketamine.

J Pharm Biomed Anal 2018 Jan 7;148:288-297. Epub 2017 Oct 7.

Pharmacokinetics and Metabolism, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.

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http://dx.doi.org/10.1016/j.jpba.2017.09.033DOI Listing
January 2018

In vitro evaluation of potential drug interactions mediated by cytochrome P450 and transporters for luseogliflozin, an SGLT2 inhibitor.

Xenobiotica 2017 Apr 20;47(4):314-323. Epub 2016 Jun 20.

a Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd. , Saitama , Japan and.

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http://dx.doi.org/10.1080/00498254.2016.1193913DOI Listing
April 2017

Metabolite profiling and enzyme reaction phenotyping of luseogliflozin, a sodium-glucose cotransporter 2 inhibitor, in humans.

Xenobiotica 2017 Apr 27;47(4):332-345. Epub 2016 Jun 27.

a Department of Pharmacokinetics and Metabolism , Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd , Saitama , Japan.

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http://dx.doi.org/10.1080/00498254.2016.1193263DOI Listing
April 2017

Antidepressant Potential of ()-Ketamine in Rodent Models: Comparison with ()-Ketamine.

J Pharmacol Exp Ther 2017 Apr 23;361(1):9-16. Epub 2017 Jan 23.

Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)

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http://dx.doi.org/10.1124/jpet.116.239228DOI Listing
April 2017

Preclinical metabolism and disposition of luseogliflozin, a novel antihyperglycemic agent.

Xenobiotica 2015 6;45(12):1105-15. Epub 2015 Jul 6.

a Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd. , Saitama , Japan .

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http://www.tandfonline.com/doi/full/10.3109/00498254.2015.10
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http://dx.doi.org/10.3109/00498254.2015.1042947DOI Listing
August 2016

Recommendation to Exclude Bile-Duct-Cannulated Rats with Hyperbilirubinemia for Proper Conduct of Biliary Drug Excretion Studies.

Drug Metab Dispos 2016 08 20;44(8):1180-3. Epub 2016 May 20.

Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co. Ltd., Saitama, Japan.

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http://dx.doi.org/10.1124/dmd.116.070532DOI Listing
August 2016

Impact of Humidity on In Vitro Human Skin Permeation Experiments for Predicting In Vivo Permeability.

J Pharm Sci 2015 Dec 13;104(12):4223-4231. Epub 2015 Oct 13.

Taisho Pharmaceutical Company, Ltd., Pharmacokinetics and Metabolism, Drug Safety and Pharmacokinetics Laboratories, Saitama 331-9530, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00223549150010
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http://dx.doi.org/10.1002/jps.24656DOI Listing
December 2015

Development, validation, and application of a surrogate analyte method for determining N-acetyl-l-aspartyl-l-glutamic acid levels in rat brain, plasma, and cerebrospinal fluid.

J Chromatogr B Analyt Technol Biomed Life Sci 2015 Oct 10;1003:1-11. Epub 2015 Sep 10.

Pharmacokinetics and Metabolism, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Kita-Ku, Saitama-Shi, Saitama 331-9530, Japan.

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http://dx.doi.org/10.1016/j.jchromb.2015.09.005DOI Listing
October 2015

Involvement of organic cation transporters in the clearance and milk secretion of thiamine in mice.

Pharm Res 2015 Jul 21;32(7):2192-204. Epub 2015 Feb 21.

Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co. Ltd., Saitama, Japan.

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http://dx.doi.org/10.1007/s11095-014-1608-8DOI Listing
July 2015

Impact of visit-to-visit variability and systolic blood pressure control on subsequent outcomes in hypertensive patients with coronary artery disease (from the HIJ-CREATE substudy).

Am J Cardiol 2015 Jul 20;116(2):236-42. Epub 2015 Apr 20.

Department of Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2015.04.011DOI Listing
July 2015

A sensitive and selective method for the quantitative analysis of miglitol in rat plasma using unique solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry.

Biomed Chromatogr 2014 Oct 7;28(10):1423-9. Epub 2014 Apr 7.

Pharmacokinetics and Metabolism, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co. Ltd, 1-403, Yoshino-cho, Kita-ku, Saitama-shi, Saitama, 331-9530, Japan.

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http://dx.doi.org/10.1002/bmc.3185DOI Listing
October 2014

SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria.

Biopharm Drug Dispos 2014 Oct 6;35(7):391-404. Epub 2014 Aug 6.

Department of Membrane Transport and Biopharmaceutics, Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan; Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd, 1-403 Yoshino-cho, Kita-ku, Saitama, 331-9530, Japan.

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http://dx.doi.org/10.1002/bdd.1909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223977PMC
October 2014

A Strategy for assessing potential drug-drug interactions of a concomitant agent against a drug absorbed via an intestinal transporter in humans.

Drug Metab Dispos 2014 Sep 8;42(9):1456-65. Epub 2014 Jul 8.

Departments of Drug Safety and Pharmacokinetics Laboratories, Saitama, Japan (A.M.-Y., K.K., S.J., J.Y.) and Molecular Function and Pharmacology Laboratories (E.G., S.U., T.T.), Taisho Pharmaceutical Co., Ltd., Saitama, Japan; Departments of Development Headquarters, (Y.N., Y.S.); and Clinical Research (S.S.), Taisho Pharmaceutical Co. Ltd., Tokyo, Japan (S.S.).

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.114.058305
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http://dx.doi.org/10.1124/dmd.114.058305DOI Listing
September 2014

Takotsubo cardiomyopathy in siblings.

Heart Vessels 2014 Jan 7;29(1):119-22. Epub 2013 Apr 7.

NTT Medical Center, 5-9-22 Higashi-Gotanda, Shinagawa-ku, Tokyo, 141-8625, Japan,

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http://dx.doi.org/10.1007/s00380-013-0345-yDOI Listing
January 2014

Chronic kidney disease and long-term outcomes of myocardial infarction.

Int J Cardiol 2013 Sep 7;167(6):2490-5. Epub 2012 May 7.

Department of Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2012.04.049DOI Listing
September 2013

A surrogate analyte method to determine D-serine in mouse brain using liquid chromatography-tandem mass spectrometry.

Anal Biochem 2013 Jan 8;432(2):124-30. Epub 2012 Oct 8.

Pharmacokinetics and Metabolism, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama-Shi, Saitama 331-9530, Japan.

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http://dx.doi.org/10.1016/j.ab.2012.09.035DOI Listing
January 2013

ATC0175: an orally active melanin-concentrating hormone receptor 1 antagonist for the potential treatment of depression and anxiety.

CNS Drug Rev 2005 ;11(4):341-52

Medicinal Pharmacology Laboratory, Medicinal Research Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama, Saitama 331-9530, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741758PMC
http://dx.doi.org/10.1111/j.1527-3458.2005.tb00052.xDOI Listing
July 2006

[Idiosyncratic drug toxicity].

Nihon Yakurigaku Zasshi 2006 Jun;127(6):473-80

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http://dx.doi.org/10.1254/fpj.127.473DOI Listing
June 2006

Identification of 4-amino-2-cyclohexylaminoquinazolines as metabolically stable melanin-concentrating hormone receptor 1 antagonists.

Bioorg Med Chem 2006 May 24;14(10):3307-19. Epub 2006 Jan 24.

Medicinal Research Laboratories, Taisho Pharmaceutical Co. Ltd, 1-403 Yoshino-cho, Kita-ku, Saitama, Saitama 331-9530, Japan.

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http://dx.doi.org/10.1016/j.bmc.2005.12.052DOI Listing
May 2006

Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization.

Circulation 2003 Mar;107(9):1322-8

Division of Cardiovascular Research and Medicine, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Mass 02135, USA.

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http://dx.doi.org/10.1161/01.cir.0000055313.77510.22DOI Listing
March 2003

Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration.

Circulation 2002 Feb;105(6):732-8

Division of Cardiovascular Research and Medicine, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Mass 02135, USA.

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http://dx.doi.org/10.1161/hc0602.103673DOI Listing
February 2002