Jun Yokota

Jun Yokota

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Jun Yokota

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Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.

Cancer Treat Res Commun 2018 1;15:21-31. Epub 2018 Mar 1.

Genomes For life-GCAT Lab. Program of Predictive and Personalized Medicine of Cancer (PMPPC), Institute for Health Science Research Germans Trias i Pujol (IGTP), Can Ruti Biomedical Campus, Crta de Can Ruti, Camí de les Escoles S/N, 08916 Badalona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ctarc.2018.02.003DOI Listing
June 2019

Pipeline design to identify key features and classify the chemotherapy response on lung cancer patients using large-scale genetic data.

BMC Syst Biol 2018 11 20;12(Suppl 5):97. Epub 2018 Nov 20.

PMPPC-IGTP. Programa de Medicina Predictiva i Personalitzada del Càncer - Institut Germans Trias i Pujol (IGTP). Genomes for Life - GCAT lab Group, Badalona, Spain.

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http://dx.doi.org/10.1186/s12918-018-0615-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245589PMC
November 2018

A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network.

EBioMedicine 2018 Jul 7;33:33-48. Epub 2018 Jul 7.

Laboratory of Molecular Carcinogenesis, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085539PMC
July 2018

Significantly mutated genes and regulatory pathways in SCLC-a meta-analysis.

Cancer Genet 2017 Oct 7;216-217:20-28. Epub 2017 Jun 7.

Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, USA; UF Health Cancer Center, University of Florida, Gainesville, FL, USA; UF Genetics Institute, University of Florida, Gainesville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677515PMC
October 2017

Erratum to: Design of a Lentiviral Vector for the Inducible Expression of MYC: A New Strategy for Construction Approach.

Mol Biotechnol 2017 Jul;59(7):305

Department of Medical Biology, Pamukkale University School of Medicine, Denizli, Turkey.

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http://dx.doi.org/10.1007/s12033-017-0011-1DOI Listing
July 2017

Design of a Lentiviral Vector for the Inducible Expression of MYC: A New Strategy for Construction Approach.

Mol Biotechnol 2017 Jun;59(6):200-206

Department of Medical Biology, Pamukkale University School of Medicine, Denizli, Turkey.

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http://dx.doi.org/10.1007/s12033-017-0006-yDOI Listing
June 2017

MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells.

Oncotarget 2016 Nov;7(47):77378-77388

Genomics and Epigenomics of Cancer Prediction Program, Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Campus Can Ruti, Badalona, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.12671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363592PMC
November 2016

Erratum to "Invasiveness and anchorage independent growth ability augmented by PTEN inactivation through the PI3K/AKT/NFkB pathway in lung cancer cells" [Lung Cancer 73 (3) (2011) 302-309].

Lung Cancer 2016 11 24;101:147. Epub 2016 May 24.

Biology Division, National Cancer Center Research Institute, Tsukiji 5-1-1, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2016.05.006DOI Listing
November 2016

Pseudo-Reentry of Atrial Tachycardia After Surgical Repair of Congenital Heart Disease.

J Cardiovasc Electrophysiol 2016 07 12;27(7):876-7. Epub 2016 Feb 12.

Department of Cardiovascular Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/jce.12932DOI Listing
July 2016

Gene aberrations for precision medicine against lung adenocarcinoma.

Cancer Sci 2016 Jun 25;107(6):713-20. Epub 2016 May 25.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1111/cas.12941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968599PMC
June 2016

Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation.

Oncotarget 2016 May;7(21):31014-28

Genomics and Epigenomics of Cancer Prediction Program, Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Campus Can Ruti, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.8826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058735PMC
May 2016

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.

Authors:
Zhaoming Wang Wei Jie Seow Kouya Shiraishi Chao A Hsiung Keitaro Matsuo Jie Liu Kexin Chen Taiki Yamji Yang Yang I-Shou Chang Chen Wu Yun-Chul Hong Laurie Burdett Kathleen Wyatt Charles C Chung Shengchao A Li Meredith Yeager Amy Hutchinson Wei Hu Neil Caporaso Maria T Landi Nilanjan Chatterjee Minsun Song Joseph F Fraumeni Takashi Kohno Jun Yokota Hideo Kunitoh Kyota Ashikawa Yukihide Momozawa Yataro Daigo Tetsuya Mitsudomi Yasushi Yatabe Toyoaki Hida Zhibin Hu Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Zhihua Yin Xuelian Li Yangwu Ren Peng Guan Jiang Chang Wen Tan Chien-Jen Chen Gee-Chen Chang Ying-Huang Tsai Wu-Chou Su Kuan-Yu Chen Ming-Shyan Huang Yuh-Min Chen Hong Zheng Haixin Li Ping Cui Huan Guo Ping Xu Li Liu Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Gening Jiang Ke Fei Jae Yong Park Yeul Hong Kim Jae Sook Sung Kyong Hwa Park Young Tae Kim Yoo Jin Jung Chang Hyun Kang In Kyu Park Hee Nam Kim Hyo-Sung Jeon Jin Eun Choi Yi Young Choi Jin Hee Kim In-Jae Oh Young-Chul Kim Sook Whan Sung Jun Suk Kim Ho-Il Yoon Sun-Seog Kweon Min-Ho Shin Adeline Seow Ying Chen Wei-Yen Lim Jianjun Liu Maria Pik Wong Victor Ho Fun Lee Bryan A Bassig Margaret Tucker Sonja I Berndt Wong-Ho Chow Bu-Tian Ji Junwen Wang Jun Xu Alan Dart Loon Sihoe James C M Ho John K C Chan Jiu-Cun Wang Daru Lu Xueying Zhao Zhenhong Zhao Junjie Wu Hongyan Chen Li Jin Fusheng Wei Guoping Wu She-Juan An Xu-Chao Zhang Jian Su Yi-Long Wu Yu-Tang Gao Yong-Bing Xiang Xingzhou He Jihua Li Wei Zheng Xiao-Ou Shu Qiuyin Cai Robert Klein William Pao Charles Lawrence H Dean Hosgood Chin-Fu Hsiao Li-Hsin Chien Ying-Hsiang Chen Chung-Hsing Chen Wen-Chang Wang Chih-Yi Chen Chih-Liang Wang Chong-Jen Yu Hui-Ling Chen Yu-Chun Su Fang-Yu Tsai Yi-Song Chen Yao-Jen Li Tsung-Ying Yang Chien-Chung Lin Pan-Chyr Yang Tangchun Wu Dongxin Lin Baosen Zhou Jinming Yu Hongbing Shen Michiaki Kubo Stephen J Chanock Nathaniel Rothman Qing Lan

Hum Mol Genet 2016 Feb 4;25(3):620-9. Epub 2016 Jan 4.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.

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http://hmg.oxfordjournals.org/content/early/2016/01/06/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731021PMC
February 2016

Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.

Int J Oncol 2015 3;46(6):2389-98. Epub 2015 Apr 3.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.3892/ijo.2015.2951DOI Listing
January 2016

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.

Authors:
Joshua N Sampson William A Wheeler Meredith Yeager Orestis Panagiotou Zhaoming Wang Sonja I Berndt Qing Lan Christian C Abnet Laufey T Amundadottir Jonine D Figueroa Maria Teresa Landi Lisa Mirabello Sharon A Savage Philip R Taylor Immaculata De Vivo Katherine A McGlynn Mark P Purdue Preetha Rajaraman Hans-Olov Adami Anders Ahlbom Demetrius Albanes Maria Fernanda Amary She-Juan An Ulrika Andersson Gerald Andriole Irene L Andrulis Emanuele Angelucci Stephen M Ansell Cecilia Arici Bruce K Armstrong Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Nikolaus Becker Yolanda Benavente Simone Benhamou Christine Berg David Van Den Berg Leslie Bernstein Kimberly A Bertrand Brenda M Birmann Amanda Black Heiner Boeing Paolo Boffetta Marie-Christine Boutron-Ruault Paige M Bracci Louise Brinton Angela R Brooks-Wilson H Bas Bueno-de-Mesquita Laurie Burdett Julie Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Alfredo Carrato Tania Carreon Angela Carta John K C Chan Ellen T Chang Gee-Chen Chang I-Shou Chang Jiang Chang Jenny Chang-Claude Chien-Jen Chen Chih-Yi Chen Chu Chen Chung-Hsing Chen Constance Chen Hongyan Chen Kexin Chen Kuan-Yu Chen Kun-Chieh Chen Ying Chen Ying-Hsiang Chen Yi-Song Chen Yuh-Min Chen Li-Hsin Chien María-Dolores Chirlaque Jin Eun Choi Yi Young Choi Wong-Ho Chow Charles C Chung Jacqueline Clavel Françoise Clavel-Chapelon Pierluigi Cocco Joanne S Colt Eva Comperat Lucia Conde Joseph M Connors David Conti Victoria K Cortessis Michelle Cotterchio Wendy Cozen Simon Crouch Marta Crous-Bou Olivier Cussenot Faith G Davis Ti Ding W Ryan Diver Miren Dorronsoro Laure Dossus Eric J Duell Maria Grazia Ennas Ralph L Erickson Maria Feychting Adrienne M Flanagan Lenka Foretova Joseph F Fraumeni Neal D Freedman Laura E Beane Freeman Charles Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina García-Closas Randy D Gascoyne Julie Gastier-Foster Mia M Gaudet J Michael Gaziano Carol Giffen Graham G Giles Edward Giovannucci Bengt Glimelius Michael Goggins Nalan Gokgoz Alisa M Goldstein Richard Gorlick Myron Gross Robert Grubb Jian Gu Peng Guan Marc Gunter Huan Guo Thomas M Habermann Christopher A Haiman Dina Halai Goran Hallmans Manal Hassan Claudia Hattinger Qincheng He Xingzhou He Kathy Helzlsouer Brian Henderson Roger Henriksson Henrik Hjalgrim Judith Hoffman-Bolton Chancellor Hohensee Theodore R Holford Elizabeth A Holly Yun-Chul Hong Robert N Hoover Pamela L Horn-Ross G M Monawar Hosain H Dean Hosgood Chin-Fu Hsiao Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang Jose-Maria Huerta Jen-Yu Hung Amy Hutchinson Peter D Inskip Rebecca D Jackson Eric J Jacobs Mazda Jenab Hyo-Sung Jeon Bu-Tian Ji Guangfu Jin Li Jin Christoffer Johansen Alison Johnson Yoo Jin Jung Rudolph Kaaks Aruna Kamineni Eleanor Kane Chang Hyun Kang Margaret R Karagas Rachel S Kelly Kay-Tee Khaw Christopher Kim Hee Nam Kim Jin Hee Kim Jun Suk Kim Yeul Hong Kim Young Tae Kim Young-Chul Kim Cari M Kitahara Alison P Klein Robert J Klein Manolis Kogevinas Takashi Kohno Laurence N Kolonel Charles Kooperberg Anne Kricker Vittorio Krogh Hideo Kunitoh Robert C Kurtz Sun-Seog Kweon Andrea LaCroix Charles Lawrence Fernando Lecanda Victor Ho Fun Lee Donghui Li Haixin Li Jihua Li Yao-Jen Li Yuqing Li Linda M Liao Mark Liebow Tracy Lightfoot Wei-Yen Lim Chien-Chung Lin Dongxin Lin Sara Lindstrom Martha S Linet Brian K Link Chenwei Liu Jianjun Liu Li Liu Börje Ljungberg Josep Lloreta Simonetta Di Lollo Daru Lu Eiluv Lund Nuria Malats Satu Mannisto Loic Le Marchand Neyssa Marina Giovanna Masala Giuseppe Mastrangelo Keitaro Matsuo Marc Maynadie James McKay Roberta McKean-Cowdin Mads Melbye Beatrice S Melin Dominique S Michaud Tetsuya Mitsudomi Alain Monnereau Rebecca Montalvan Lee E Moore Lotte Maxild Mortensen Alexandra Nieters Kari E North Anne J Novak Ann L Oberg Kenneth Offit In-Jae Oh Sara H Olson Domenico Palli William Pao In Kyu Park Jae Yong Park Kyong Hwa Park Ana Patiño-Garcia Sofia Pavanello Petra H M Peeters Reury-Perng Perng Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Ludmila Prokunina-Olsson Biyun Qian You-Lin Qiao Marco Rais Elio Riboli Jacques Riby Harvey A Risch Cosmeri Rizzato Rebecca Rodabough Eve Roman Morgan Roupret Avima M Ruder Silvia de Sanjose Ghislaine Scelo Alan Schned Fredrick Schumacher Kendra Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Veronica Wendy Setiawan Gianluca Severi Richard K Severson Tait D Shanafelt Hongbing Shen Wei Shen Min-Ho Shin Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesúmaga Alan Dart Loon Sihoe Christine F Skibola Alex Smith Martyn T Smith Melissa C Southey John J Spinelli Anthony Staines Meir Stampfer Marianna C Stern Victoria L Stevens Rachael S Stolzenberg-Solomon Jian Su Wu-Chou Su Malin Sund Jae Sook Sung Sook Whan Sung Wen Tan Wei Tang Adonina Tardón David Thomas Carrie A Thompson Lesley F Tinker Roberto Tirabosco Anne Tjønneland Ruth C Travis Dimitrios Trichopoulos Fang-Yu Tsai Ying-Huang Tsai Margaret Tucker Jenny Turner Claire M Vajdic Roel C H Vermeulen Danylo J Villano Paolo Vineis Jarmo Virtamo Kala Visvanathan Jean Wactawski-Wende Chaoyu Wang Chih-Liang Wang Jiu-Cun Wang Junwen Wang Fusheng Wei Elisabete Weiderpass George J Weiner Stephanie Weinstein Nicolas Wentzensen Emily White Thomas E Witzig Brian M Wolpin Maria Pik Wong Chen Wu Guoping Wu Junjie Wu Tangchun Wu Wei Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Ping Xu Pan-Chyr Yang Tsung-Ying Yang Yuanqing Ye Zhihua Yin Jun Yokota Ho-Il Yoon Chong-Jen Yu Herbert Yu Kai Yu Jian-Min Yuan Andrew Zelenetz Anne Zeleniuch-Jacquotte Xu-Chao Zhang Yawei Zhang Xueying Zhao Zhenhong Zhao Hong Zheng Tongzhang Zheng Wei Zheng Baosen Zhou Meng Zhu Mariagrazia Zucca Simina M Boca James R Cerhan Giovanni M Ferri Patricia Hartge Chao Agnes Hsiung Corrado Magnani Lucia Miligi Lindsay M Morton Karin E Smedby Lauren R Teras Joseph Vijai Sophia S Wang Paul Brennan Neil E Caporaso David J Hunter Peter Kraft Nathaniel Rothman Debra T Silverman Susan L Slager Stephen J Chanock Nilanjan Chatterjee

J Natl Cancer Inst 2015 Dec 12;107(12):djv279. Epub 2015 Oct 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JNS, OP, SIB, QL, CCA, LTA, JDF, MTL, LM, SAS, PRT, KAM, PR, DA, DB, BAB, AB, LBr, WHC, CCC, JSC, JFFJr, NDF, LEBF, MGC, AMG, RNH, NH, WH, PDI, BTJ, CK, CMK, LML, MSL, LEM, LPO, RSSS, WeiT, MT, CWa, SW, NW, KY, PH, LMM, NEC, NR, DTS, SJC, NC); Information Management Services, Silver Spring, MD (WAW, CG); Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MD (MY, ZW, LBu, AH, CLi); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (IDV, KAB, BMB, CoC, MCB, CF, EG, SL, JP, MSt, DJH); Department of Epidemiology, Harvard School of Public Health, Boston, MA (IDV, OA, KAB, CoC, MCB, EG, RSK, SL, JP, HDS, MSt, DTr, DJH, PK); Ontario Health Study, Toronto, Ontario, Canada (MPP); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (HOA, EWe); Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (AA, MF); UCL Cancer Institute, London, UK (MFA, AMF, DH); Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, UK (MFA, AMF, DH, RT); Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China (SJA, JS, YLW, XCZ); Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden (UA, RH, BSM); Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, MO (GAJr, RGIII); Litwin Centre for Cancer Genetics, University of Toronto, Ontario, Canada (ILA, NG, JSW); Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (ILA, SG, NG, JSW); Hematology Unit, Ospedale Oncologico di Riferimento Regionale A. Businco, Cagliari, Italy (EA); Department of Medicin

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http://kooperberg.fhcrc.org/papers/2015sampson.pdf
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv27
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http://dx.doi.org/10.1093/jnci/djv279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806328PMC
December 2015

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.

Cancer Res 2015 Sep 24;75(18):3936-45. Epub 2015 Jul 24.

Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain. Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain. Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3702DOI Listing
September 2015

Comprehensive genomic profiles of small cell lung cancer.

Nature 2015 Aug 13;524(7563):47-53. Epub 2015 Jul 13.

1] Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany. [2] Department of Pathology, University Hospital Cologne, 50937 Cologne, Germany.

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http://dx.doi.org/10.1038/nature14664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861069PMC
August 2015

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia.

Authors:
Mitchell J Machiela Chao Agnes Hsiung Xiao-Ou Shu Wei Jie Seow Zhaoming Wang Keitaro Matsuo Yun-Chul Hong Adeline Seow Chen Wu H Dean Hosgood Kexin Chen Jiu-Cun Wang Wanqing Wen Richard Cawthon Nilanjan Chatterjee Wei Hu Neil E Caporaso Jae Yong Park Chien-Jen Chen Yeul Hong Kim Young Tae Kim Maria Teresa Landi Hongbing Shen Charles Lawrence Laurie Burdett Meredith Yeager I-Shou Chang Tetsuya Mitsudomi Hee Nam Kim Gee-Chen Chang Bryan A Bassig Margaret Tucker Fusheng Wei Zhihua Yin She-Juan An Biyun Qian Victor Ho Fun Lee Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Jin Hee Kim Yu-Tang Gao Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Amy Hutchinson Wen-Chang Wang Robert J Klein Charles C Chung In-Jae Oh Kuan-Yu Chen Sonja I Berndt Wei Wu Jiang Chang Xu-Chao Zhang Ming-Shyan Huang Hong Zheng Junwen Wang Xueying Zhao Yuqing Li Jin Eun Choi Wu-Chou Su Kyong Hwa Park Sook Whan Sung Yuh-Min Chen Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen William Pao Young-Chul Kim Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Jian Su Chih-Liang Wang Haixin Li Alan Dart Loon Sihoe Zhenhong Zhao Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Takashi Kohno Sun-Seog Kweon Chih-Yi Chen Roel C H Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Wong-Ho Chow Bu-Tian Ji John K C Chan Minjie Chu Yao-Jen Li Jun Yokota Jihua Li Hongyan Chen Yong-Bing Xiang Chong-Jen Yu Hideo Kunitoh Guoping Wu Li Jin Yen-Li Lo Kouya Shiraishi Ying-Hsiang Chen Hsien-Chih Lin Tangchun Wu Maria Pik Wong Yi-Long Wu Pan-Chyr Yang Baosen Zhou Min-Ho Shin Joseph F Fraumeni Wei Zheng Dongxin Lin Stephen J Chanock Nathaniel Rothman Qing Lan

Int J Cancer 2015 Jul 29;137(2):311-9. Epub 2014 Dec 29.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1002/ijc.29393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733320PMC
July 2015

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers.

J Thorac Oncol 2015 Jul;10(7):1037-48

*Laboratory of Human Carcinogenesis, NCI-CCR, National Institutes of Health, Bethesda, Maryland; †Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo, Japan; ‡Genetics Branch, NCI-CCR, National Institutes of Health, Bethesda, Maryland; §Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; ‖Department of Chemical and Biological Working Environment, National Institute of Occupational Health, Oslo, Norway; and ¶Genomics and Epigenomics of Cancer Prediction Program, Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Badalona (Barcelona), Spain.

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http://dx.doi.org/10.1097/JTO.0000000000000560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493931PMC
July 2015

Development of lung adenocarcinomas with exclusive dependence on oncogene fusions.

Cancer Res 2015 Jun 8;75(11):2264-71. Epub 2015 Apr 8.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3282DOI Listing
June 2015

Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing.

Carcinogenesis 2015 Jun 11;36(6):616-21. Epub 2015 Apr 11.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan, Cancer Genome Biology Group, Institute of Predictive and Personalized Medicine of Cancer, 08916 Barcelona, Spain

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http://dx.doi.org/10.1093/carcin/bgv026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462675PMC
June 2015

Electromagnetic interference between continuous-flow left ventricular assist device and cardiac resynchronization therapy defibrillator due to an unrecognized mechanism.

Int J Cardiol 2015 Jan 5;179:510-3. Epub 2014 Nov 5.

University of Tokyo Hospital, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan; Department of Cardiovascular Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2014.11.021DOI Listing
January 2015

The expression of four genes as a prognostic classifier for stage I lung adenocarcinoma in 12 independent cohorts.

Cancer Epidemiol Biomarkers Prev 2014 Dec 21;23(12):2884-94. Epub 2014 Sep 21.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257875PMC
December 2014

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis.

J Thorac Oncol 2014 Sep;9(9):1324-31

*Division of Thoracic Oncology, National Cancer Center Hospital East; †Exploratory Oncology Research and Clinical Trial Center, National Cancer Center; ‡Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East; §Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan; and ‖Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1097/JTO.0000000000000250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154841PMC
September 2014

Druggable oncogene fusions in invasive mucinous lung adenocarcinoma.

Clin Cancer Res 2014 Jun 11;20(12):3087-93. Epub 2014 Apr 11.

Authors' Affiliations: Divisions of Genome Biology, Genetics, and Refractory Cancer Research, National Cancer Center Research Institute, Divisions of Pathology and Clinical Laboratories, Thoracic Surgery, and Thoracic Oncology, National Cancer Center Hospital, Chuo-ku; Department of Metabolic Disorder, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo; Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, Japan; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland; and The Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Barcelona, Spain

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-0107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329293PMC
June 2014

ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma.

Cancer Sci 2014 Apr 19;105(4):490-7. Epub 2014 Mar 19.

Department of Pathology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.

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http://doi.wiley.com/10.1111/cas.12363
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http://dx.doi.org/10.1111/cas.12363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317802PMC
April 2014

TSPAN2 is involved in cell invasion and motility during lung cancer progression.

Cell Rep 2014 Apr 13;7(2):527-538. Epub 2014 Apr 13.

Division of Refractory Cancer Research, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.027DOI Listing
April 2014

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1.

Cancer Discov 2014 Mar 20;4(3):292-303. Epub 2013 Dec 20.

1Genes and Cancer Group, Cancer Epigenetics and Biology Program (PEBC); 2Translational Research Laboratory, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona; 3Instituto de Biomedicina de Sevilla (IBiS), 4Department of Pathology, Hospital Universitario Virgen del Rocío, Consejo Superior de Investigaciones Cientificas (CSIC), Universidad de Sevilla, Seville; 5Division of Oncology, Centro para la Investigación Medica Aplicada (CIMA), University of Navarre, Pamplona, Spain; 6MRC-Holland, Amsterdam, the Netherlands; and 7Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0799DOI Listing
March 2014

PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner.

Int J Mol Med 2014 Mar 27;33(3):534-42. Epub 2013 Dec 27.

Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, Yahaba, Iwate 028‑3694, Japan.

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http://dx.doi.org/10.3892/ijmm.2013.1606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926498PMC
March 2014

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer.

Genes Chromosomes Cancer 2013 Sep 28;52(9):802-16. Epub 2013 May 28.

Division of Multistep Carcinogenesis, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1002/gcc.22076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806277PMC
September 2013

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

Cancer Res 2013 Sep 19;73(17):5508-18. Epub 2013 Jul 19.

Divisions of Genome Biology and Multistep Carcinogenesis, National Cancer Center Research Institute, Tokyo, Japan, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4593DOI Listing
September 2013

Inactivating mutations in SWI/SNF chromatin remodeling genes in human cancer.

Jpn J Clin Oncol 2013 Sep 30;43(9):849-55. Epub 2013 Jul 30.

Division of Genome Biology, National Cancer Center Research Institute, 1-1, Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1093/jjco/hyt101DOI Listing
September 2013

NuMA is required for the selective induction of p53 target genes.

Mol Cell Biol 2013 Jun 15;33(12):2447-57. Epub 2013 Apr 15.

Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1128/MCB.01221-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700099PMC
June 2013

Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer.

Cancer Genet 2013 Mar 9;206(3):73-80. Epub 2013 Mar 9.

Department of Medical Biology, School of Medicine, Pamukkale University, Denizli, Turkey.

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http://dx.doi.org/10.1016/j.cancergen.2013.01.005DOI Listing
March 2013

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

Authors:
Qing Lan Chao A Hsiung Keitaro Matsuo Yun-Chul Hong Adeline Seow Zhaoming Wang H Dean Hosgood Kexin Chen Jiu-Cun Wang Nilanjan Chatterjee Wei Hu Maria Pik Wong Wei Zheng Neil Caporaso Jae Yong Park Chien-Jen Chen Yeul Hong Kim Young Tae Kim Maria Teresa Landi Hongbing Shen Charles Lawrence Laurie Burdett Meredith Yeager Jeffrey Yuenger Kevin B Jacobs I-Shou Chang Tetsuya Mitsudomi Hee Nam Kim Gee-Chen Chang Bryan A Bassig Margaret Tucker Fusheng Wei Zhihua Yin Chen Wu She-Juan An Biyun Qian Victor Ho Fun Lee Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Jin Hee Kim Yu-Tang Gao Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Amy Hutchinson Wen-Chang Wang Robert Klein Charles C Chung In-Jae Oh Kuan-Yu Chen Sonja I Berndt Xingzhou He Wei Wu Jiang Chang Xu-Chao Zhang Ming-Shyan Huang Hong Zheng Junwen Wang Xueying Zhao Yuqing Li Jin Eun Choi Wu-Chou Su Kyong Hwa Park Sook Whan Sung Xiao-Ou Shu Yuh-Min Chen Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen William Pao Young-Chul Kim Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Jian Su Chih-Liang Wang Haixin Li Alan Dart Loon Sihoe Zhenhong Zhao Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Takashi Kohno Sun-Seog Kweon Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Wong-Ho Chow Bu-Tian Ji John K C Chan Minjie Chu Yao-Jen Li Jun Yokota Jihua Li Hongyan Chen Yong-Bing Xiang Chong-Jen Yu Hideo Kunitoh Guoping Wu Li Jin Yen-Li Lo Kouya Shiraishi Ying-Hsiang Chen Hsien-Chih Lin Tangchun Wu Yi-Long Wu Pan-Chyr Yang Baosen Zhou Min-Ho Shin Joseph F Fraumeni Dongxin Lin Stephen J Chanock Nathaniel Rothman

Nat Genet 2012 Dec 11;44(12):1330-5. Epub 2012 Nov 11.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/ng.2456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169232PMC
December 2012

Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining.

Int J Radiat Oncol Biol Phys 2012 Nov 13;84(3):815-21. Epub 2012 Mar 13.

Division of Multistep Carcinogenesis, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijrobp.2012.01.017DOI Listing
November 2012

Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma.

Genes Chromosomes Cancer 2012 May 3;51(5):462-72. Epub 2012 Feb 3.

Division of Multistep Carcinogenesis, National Cancer Center Research Institute, Tokyo, Japan.

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http://doi.wiley.com/10.1002/gcc.21933
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May 2012

Invasiveness and anchorage independent growth ability augmented by PTEN inactivation through the PI3K/AKT/NFkB pathway in lung cancer cells.

Lung Cancer 2011 Sep 17;73(3):302-9. Epub 2011 Feb 17.

Medical Biology Department, School of Medicine, Pamukkale University, Kinikli, Denizli, Turkey.

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http://dx.doi.org/10.1016/j.lungcan.2011.01.012DOI Listing
September 2011

The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: a retrospective analysis of three cohorts.

Clin Cancer Res 2011 Apr 24;17(7):1875-82. Epub 2011 Feb 24.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477786PMC
April 2011

Contribution of the TP53, OGG1, CHRNA3, and HLA-DQA1 genes to the risk for lung squamous cell carcinoma.

J Thorac Oncol 2011 Apr;6(4):813-7

Biology Division, National Cancer Center Research Institute; †Division of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e3181ee80efDOI Listing
April 2011

MYC amplification as a prognostic marker of early-stage lung adenocarcinoma identified by whole genome copy number analysis.

Clin Cancer Res 2011 Mar 10;17(6):1481-9. Epub 2010 Dec 10.

Biology Division, National Cancer Center Research Institute; Cancer Genomics Project, The University of Tokyo, Tokyo, Japan.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-10-2484DOI Listing
March 2011

Genetic basis for susceptibility to lung cancer: Recent progress and future directions.

Adv Cancer Res 2010 ;109:51-72

Biology Division, National Cancer Center Research Institute,Tsukiji, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/B978-0-12-380890-5.00002-8DOI Listing
February 2011

Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells.

Lung Cancer 2010 Nov 5;70(2):136-45. Epub 2010 Mar 5.

Biology Division, National Cancer Center Research Institute, 1-1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2010.02.004DOI Listing
November 2010

Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.

Cancer Sci 2010 Aug 19;101(8):1891-6. Epub 2010 May 19.

Division of Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01622.xDOI Listing
August 2010

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

Mol Cell Biol 2010 Apr 1;30(7):1620-33. Epub 2010 Feb 1.

Radiobiology Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00810-09
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http://dx.doi.org/10.1128/MCB.00810-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838062PMC
April 2010

Identification of a function-specific mutation of clathrin heavy chain (CHC) required for p53 transactivation.

J Mol Biol 2009 Dec 18;394(3):460-71. Epub 2009 Sep 18.

Radiobiology Division, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jmb.2009.09.029DOI Listing
December 2009

ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.

Int J Cancer 2009 Sep;125(6):1306-15

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1002/ijc.24437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790157PMC
September 2009

A gene-alteration profile of human lung cancer cell lines.

Hum Mutat 2009 Aug;30(8):1199-206

Lung Cancer Group, Molecular Pathology Programme, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain.

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http://dx.doi.org/10.1002/humu.21028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900846PMC
August 2009

Bronchioloalveolar carcinoma (lepidic growth) component is a more useful prognostic factor than lymph node metastasis.

J Thorac Oncol 2009 Aug;4(8):951-8

Department of Pathology, Institute of Basic Medical Science, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e3181ad8631DOI Listing
August 2009

The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer.

Hum Mol Genet 2009 Apr 19;18(7):1343-52. Epub 2009 Jan 19.

Lung Cancer Group, Molecular Pathology Programme, Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1093/hmg/ddp034DOI Listing
April 2009

Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma.

Cancer Sci 2009 Feb;100(2):225-32

Division of Oncology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2008.01030.xDOI Listing
February 2009

Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas.

Cancer Res 2009 Feb 3;69(4):1615-23. Epub 2009 Feb 3.

Biology Division, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3218DOI Listing
February 2009

Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese.

Carcinogenesis 2009 Jan 12;30(1):65-70. Epub 2008 Nov 12.

Biology Division, National Cancer Center Research Institute, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1093/carcin/bgn257DOI Listing
January 2009

Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrations.

Genes Cells 2008 Oct 29;13(10):987-99. Epub 2008 Aug 29.

Biology Division, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2008.01226.xDOI Listing
October 2008

Association of KRAS polymorphisms with risk for lung adenocarcinoma accompanied by atypical adenomatous hyperplasias.

Carcinogenesis 2008 May 24;29(5):957-63. Epub 2008 Feb 24.

Biology Division, National Cancer Center Research Institute, Tokyo 1040045, Japan.

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http://dx.doi.org/10.1093/carcin/bgn048DOI Listing
May 2008

Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines.

Hum Mutat 2008 May;29(5):617-22

Lung Cancer Group, Molecular Pathology Programme, Centro Nacional de Investigaciones Oncologicas(CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/humu.20730DOI Listing
May 2008

BREK/LMTK2 is a myosin VI-binding protein involved in endosomal membrane trafficking.

Genes Cells 2008 May;13(5):483-95

Department of Life Sciences, Graduate School of Arts and Sciences, University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo 153-8902, Japan.

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http://doi.wiley.com/10.1111/j.1365-2443.2008.01184.x
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May 2008

Homozygous deletion scanning of the lung cancer genome at a 100-kb resolution.

Genes Chromosomes Cancer 2007 Nov;46(11):1000-10

Biology Division, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1002/gcc.20485DOI Listing
November 2007

CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma.

Mol Cell Biol 2007 Nov 4;27(21):7649-60. Epub 2007 Sep 4.

Growth Factor Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.01246-07
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http://dx.doi.org/10.1128/MCB.01246-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169043PMC
November 2007

Use of a cytokine gene expression signature in lung adenocarcinoma and the surrounding tissue as a prognostic classifier.

J Natl Cancer Inst 2007 Aug 8;99(16):1257-69. Epub 2007 Aug 8.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1093/jnci/djm083DOI Listing
August 2007

HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growth.

Biochem Biophys Res Commun 2007 May 19;356(4):851-6. Epub 2007 Mar 19.

Biology Division, National Cancer Center Research Institute, 1-1, Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.03.060DOI Listing
May 2007

Restored expression of the MYO18B gene suppresses orthotopic growth and the production of bloody pleural effusion by human malignant pleural mesothelioma cells in SCID mice.

Oncol Res 2006 ;16(5):235-43

Department of Internal Medicine and Molecular Therapeutics, University of Tokushima Graduate School, Tokushima 770-8503, Japan.

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March 2007