Jun Takeuchi

Jun Takeuchi

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Silicone oil-associated retinal light exposure under a surgical microscope.

Acta Ophthalmol 2019 Aug 30;97(5):e742-e746. Epub 2019 Jan 30.

Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1111/aos.14038DOI Listing
August 2019

Effect of intra-articular hyaluronan injection on inflammation and bone remodeling in the epiphyses and metaphyses of the knee in a murine model of joint injury.

Am J Transl Res 2019 15;11(6):3280-3300. Epub 2019 Jun 15.

Department of Internal Medicine (Rheumatology), Rush University Medical Center Chicago, IL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614662PMC
June 2019

Accumulation of hyaluronic acid in stromal cells modulates osteoclast formation by regulation of receptor activator of nuclear factor kappa-B ligand expression.

Biochem Biophys Res Commun 2019 May 23;512(3):537-543. Epub 2019 Mar 23.

Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.03.137DOI Listing
May 2019

Cardiac septation in heart development and evolution.

Dev Growth Differ 2019 Jan 13;61(1):114-123. Epub 2018 Dec 13.

Faculty of Life Sciences, Department of Applied Biosciences, Toyo University, Ora-gun, Japan.

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http://dx.doi.org/10.1111/dgd.12580DOI Listing
January 2019

Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs.

BMC Genomics 2018 Dec 27;19(1):967. Epub 2018 Dec 27.

Division of Cardiovascular Regeneration, Institute of Molecular and Cellular Biosciences, the University of Tokyo, Hongo, Bunkyo, Tokyo, Japan.

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http://dx.doi.org/10.1186/s12864-018-5233-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307297PMC
December 2018

HERC2 Facilitates BLM and WRN Helicase Complex Interaction with RPA to Suppress G-Quadruplex DNA.

Cancer Res 2018 11 2;78(22):6371-6385. Epub 2018 Oct 2.

Department of Translational Oncology, St. Marianna University Graduate School of Medicine, Kawasaki, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-1877DOI Listing
November 2018

PREDICTIVE FACTORS OF SURGICAL OUTCOMES IN VITRECTOMY FOR MYOPIC TRACTION MACULOPATHY.

Retina 2018 09;38 Suppl 1:S23-S30

Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1097/IAE.0000000000001927DOI Listing
September 2018

Amyloid deposition and CBF patterns predict conversion of mild cognitive impairment to dementia.

Neurol Sci 2018 Sep 23;39(9):1597-1602. Epub 2018 Jun 23.

Department of Neurology, Osaka City University Graduate School of Medicine, 1-4-3, Asahimachi ,Abeno-ku, Osaka, 545-8585, Japan.

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http://dx.doi.org/10.1007/s10072-018-3477-0DOI Listing
September 2018

Rationally Designed Strigolactone Analogs as Antagonists of the D14 Receptor.

Plant Cell Physiol 2018 Aug;59(8):1545-1554

Department of Applied Biological Chemistry, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1093/pcp/pcy087DOI Listing
August 2018

[A case of neurosarcoidosis with recurrent brainstem infarction, obstructive hydrocephalus and brainstem atrophy].

Rinsho Shinkeigaku 2018 Jul 30;58(7):445-450. Epub 2018 Jun 30.

Department of Neurology, Osaka City University.

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http://dx.doi.org/10.5692/clinicalneurol.cn-001155DOI Listing
July 2018

Structure-Based Chemical Design of Abscisic Acid Antagonists That Block PYL-PP2C Receptor Interactions.

ACS Chem Biol 2018 05 11;13(5):1313-1321. Epub 2018 Apr 11.

Faculty of Agriculture , Shizuoka University , Shizuoka 422-8529 , Japan.

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http://dx.doi.org/10.1021/acschembio.8b00105DOI Listing
May 2018

Review of the Mechanism of Action for Supartz FX in Knee Osteoarthritis.

Cartilage 2018 01 29;9(1):11-20. Epub 2016 Dec 29.

3 Pharmaceuticals Information Group, Seikagaku Corporation, Tokyo, Japan.

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http://dx.doi.org/10.1177/1947603516684588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724672PMC
January 2018

Sexual dimorphisms of mRNA and miRNA in human/murine heart disease.

PLoS One 2017 13;12(7):e0177988. Epub 2017 Jul 13.

Division of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical Dental University, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177988PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509429PMC
September 2017

Potent mechanism-based sirtuin-2-selective inhibition by an -generated occupant of the substrate-binding site, "selectivity pocket" and NAD-binding site.

Chem Sci 2017 Sep 21;8(9):6400-6408. Epub 2017 Jul 21.

Graduate School of Medical Science , Kyoto Prefectural University of Medicine , 1-5 Shimogamohangi-cho, Sakyo-ku , Kyoto 606-0823 , Japan . Email:

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http://dx.doi.org/10.1039/c7sc02738aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628579PMC
September 2017

Insulin-Induced Distant Site Lipoatrophy.

Diabetes Care 2017 06 10;40(6):e67-e68. Epub 2017 Apr 10.

Division of Rheumatology, Endocrinology, and Nephrology, Hokkaido University Hospital, Sapporo, Japan.

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http://dx.doi.org/10.2337/dc16-2385DOI Listing
June 2017

High molecular weight hyaluronic acid regulates MMP13 expression in chondrocytes via DUSP10/MKP5.

J Orthop Res 2017 02 29;35(2):331-339. Epub 2016 Apr 29.

Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu, Fukuoka, Japan.

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http://dx.doi.org/10.1002/jor.23266DOI Listing
February 2017

Abscinazole-E3M, a practical inhibitor of abscisic acid 8'-hydroxylase for improving drought tolerance.

Sci Rep 2016 11 14;6:37060. Epub 2016 Nov 14.

College of Agriculture, Academic Institute, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan.

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http://dx.doi.org/10.1038/srep37060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107945PMC
November 2016

Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice.

Dev Growth Differ 2016 May 29;58(4):367-82. Epub 2016 Apr 29.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1111/dgd.12281DOI Listing
May 2016

Sall1 transiently marks undifferentiated heart precursors and regulates their fate.

J Mol Cell Cardiol 2016 Mar 11;92:158-62. Epub 2016 Feb 11.

Division of Cardiovascular Regeneration, Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo, Tokyo 113-0032, Japan; Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-0033, Japan; AMED, Research Center Network for Realization of Regenerative Medicine, Projects for Technological Development, Japan; JST PESTO, Understanding Life by iPS Cells Technology, Sanbancho building, Sanbancho 5, Chiyoda-ku, Tokyo 102-0075, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789172PMC
March 2016

The BARD1/HP1 interaction: Another clue to heterochromatin involvement in homologous recombination.

Mol Cell Oncol 2016 Mar 14;3(2):e1030535. Epub 2015 Apr 14.

Department of Translational Oncology; St. Marianna University Graduate School of Medicine ; Kawasaki, Japan.

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http://dx.doi.org/10.1080/23723556.2015.1030535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905335PMC
March 2016

The selectivity of 6-nor-ABA and 7'-nor-ABA for abscisic acid receptor subtypes.

Bioorg Med Chem Lett 2015 Sep 3;25(17):3507-10. Epub 2015 Jul 3.

Graduate School of Agriculture, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan; Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan; Graduate School of Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.06.088DOI Listing
September 2015

Discovery of a potent, orally available dual CysLT₁ and CysLT₂ antagonist with dicarboxylic acid.

Bioorg Med Chem 2015 May 7;23(9):2079-97. Epub 2015 Mar 7.

Medicinal Chemistry Research Laboratories, Ono Pharmaceutical Co., Ltd, 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan.

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http://dx.doi.org/10.1016/j.bmc.2015.03.011DOI Listing
May 2015

Conformationally restricted 3'-modified ABA analogs for controlling ABA receptors.

Org Biomol Chem 2015 Apr 11;13(14):4278-88. Epub 2015 Mar 11.

Graduate School of Agriculture, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan.

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http://dx.doi.org/10.1039/c4ob02662dDOI Listing
April 2015

Discovery of Highly Potent Dual CysLT1 and CysLT2 Antagonist.

ACS Med Chem Lett 2014 Nov 6;5(11):1230-4. Epub 2014 Oct 6.

Medicinal Chemistry Research Laboratories and Department of Biology & Pharmacology, Ono Pharmaceutical Co., Ltd. , 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan.

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http://dx.doi.org/10.1021/ml500298yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233365PMC
November 2014

Multi-investigator letter on reproducibility of neonatal heart regeneration following apical resection.

Stem Cell Reports 2014 Jul 8;3(1). Epub 2014 Jul 8.

Brigham Regenerative Medicine Center, Brigham and Women's Hospital Cardiovascular Division, Brigham and Women's Hospital Partners Research Facility, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.stemcr.2014.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110774PMC
July 2014

Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions.

Nat Chem Biol 2014 Jun 4;10(6):477-82. Epub 2014 May 4.

1] Graduate School of Science and Technology, Shizuoka University, Shizuoka, Japan. [2] Graduate School of Agriculture, Shizuoka University, Shizuoka, Japan. [3] Research Institute of Green Science and Technology, Shizuoka University, Shizuoka, Japan.

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http://search.proquest.com/openview/3a5ebb0226cbdcf049428718
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http://dx.doi.org/10.1038/nchembio.1524DOI Listing
June 2014

Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice.

Bone 2014 Mar 10;60:68-77. Epub 2013 Dec 10.

Laboratory of Epigenetic Skeletal Diseases, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan; Division of Integrative Pathophysiology, Proteo-Science Center, Graduate School of Medicine, Ehime University, Ehime, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2013.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944732PMC
March 2014

Hox5 interacts with Plzf to restrict Shh expression in the developing forelimb.

Proc Natl Acad Sci U S A 2013 Nov 11;110(48):19438-43. Epub 2013 Nov 11.

Department of Internal Medicine, Division of Molecular Medicine and Genetics, University of Michigan, Ann Arbor, MI 48109.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1315075110
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http://dx.doi.org/10.1073/pnas.1315075110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845161PMC
November 2013

Clinical features of Pittsburgh compound-B-negative dementia.

Dement Geriatr Cogn Disord 2012 4;34(2):112-20. Epub 2012 Sep 4.

Department of Geriatrics and Neurology, Osaka City University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1159/000341577DOI Listing
February 2013

Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors.

J Med Chem 2012 Jun 12;55(12):5760-73. Epub 2012 Jun 12.

Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 13 Taishogun Nishitakatsukasa-cho, Kita-ku, Kyoto 603-8334, Japan.

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http://dx.doi.org/10.1021/jm3002108DOI Listing
June 2012

Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism.

Arthritis Res Ther 2012 Jun 21;14(3):R151. Epub 2012 Jun 21.

Department of Internal Medicine (Rheumatology), Rush University Medical Center, 1611 West Harrison Street Suite 510, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1186/ar3887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446537PMC
June 2012

Pittsburgh compound B-negative dementia: a possibility of misdiagnosis of patients with non-alzheimer disease-type dementia as having AD.

J Geriatr Psychiatry Neurol 2011 Sep 12;24(3):123-6. Epub 2011 Jul 12.

Department of Geriatrics and Neurology, Osaka City University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1177/0891988711409410DOI Listing
September 2011

Epigenetic factors and cardiac development.

Cardiovasc Res 2011 Jul 23;91(2):203-11. Epub 2011 May 23.

Cardiovascular Regeneration, Institute of Molecular and Cellular Biosciences, University of Tokyo, Tokyo, Japan.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1093/cvr/cvr138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125076PMC
July 2011

Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors.

Nature 2009 Jun 26;459(7247):708-11. Epub 2009 Apr 26.

Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/nature08039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728356PMC
June 2009

Structure and biological activity of novel FN analogs as flowering inducers.

Bioorg Med Chem 2008 Dec 11;16(23):10043-8. Epub 2008 Oct 11.

Graduate School of Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan.

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http://dx.doi.org/10.1016/j.bmc.2008.10.014DOI Listing
December 2008

Tbx5-dependent pathway regulating diastolic function in congenital heart disease.

Proc Natl Acad Sci U S A 2008 Apr 31;105(14):5519-24. Epub 2008 Mar 31.

Programme in Developmental and Stem Cell Biology, Division of Cardiology and Labatt Family Heart Centre, Programme in Physiology and Experimental Medicine, and Mouse Imaging Centre, Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1073/pnas.0801779105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291114PMC
April 2008

[A case of maternally inherited diabetes with deafness (MIDD) occurring at an advanced age].

Nihon Ronen Igakkai Zasshi 2008 Jan;45(1):95-9

Department of Medicine II, Hokkaido University Graduate School of Medicine.

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http://dx.doi.org/10.3143/geriatrics.45.95DOI Listing
January 2008

Irxl1, a divergent Iroquois homeobox family transcription factor gene.

Gene Expr Patterns 2007 Jan 26;7(1-2):51-6. Epub 2006 May 26.

Programs in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, Ont., Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S1567133X0600101
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http://dx.doi.org/10.1016/j.modgep.2006.05.007DOI Listing
January 2007

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry.

Proc Natl Acad Sci U S A 2007 Jan 8;104(3):846-51. Epub 2007 Jan 8.

Department of Cardiovascular Research, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1073/pnas.0608118104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783402PMC
January 2007

First evidence for a uniquely spin-polarized quartet photoexcited state of a pi-conjugated spin system generated via the ion-pair state.

Angew Chem Int Ed Engl 2006 Jul;45(28):4666-70

Department of Material Science, Graduate School of Science, Osaka City University, 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan.

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http://dx.doi.org/10.1002/anie.200600898DOI Listing
July 2006

Clinical analysis of cognitive function in diabetic patients by MMSE and SPECT.

Diabetes Res Clin Pract 2006 May 1;72(2):142-7. Epub 2005 Dec 1.

Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, North 15th, West 7th, Sapporo, Hokkaido 060-8638, Japan.

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http://dx.doi.org/10.1016/j.diabres.2005.10.012DOI Listing
May 2006

Chromatin modification and remodeling in heart development.

ScientificWorldJournal 2006 Apr 24;6:1851-61. Epub 2006 Apr 24.

Programmes in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1100/tsw.2006.315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917192PMC
April 2006

Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.

Nat Genet 2006 Feb 25;38(2):175-83. Epub 2005 Dec 25.

Programs in Cardiovascular Research, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1038/ng1707DOI Listing
February 2006

Expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase/PFKFB3 isoforms in adipocytes and their potential role in glycolytic regulation.

Diabetes 2005 Dec;54(12):3349-57

Department of Medicine II, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan.

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http://dx.doi.org/10.2337/diabetes.54.12.3349DOI Listing
December 2005

An epidemiological study of HBV, HCV and HTLV-I in Sherpas of Nepal.

Asian Pac J Cancer Prev 2004 Oct-Dec;5(4):370-3

Department of Laboratory Medicine, Hokkaido University Hospital, Sapporo 060-8648, Japan.

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February 2005

Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.

Nature 2004 Nov;432(7013):107-12

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

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http://dx.doi.org/10.1038/nature03071DOI Listing
November 2004

Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling.

Dev Cell 2004 Jan;6(1):43-53

Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara, 630-0101, Japan.

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January 2004

Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis.

Development 2003 Dec 22;130(24):5953-64. Epub 2003 Oct 22.

Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara 630-0101, Japan.

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http://dx.doi.org/10.1242/dev.00797DOI Listing
December 2003

Tbx5 and Tbx4 trigger limb initiation through activation of the Wnt/Fgf signaling cascade.

Development 2003 Jun;130(12):2729-39

Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara 630-0101, Japan.

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http://dx.doi.org/10.1242/dev.00474DOI Listing
June 2003

Characterization of an anti-decorin monoclonal antibody, and its utility.

J Biochem 2002 Dec;132(6):997-1002

Institute for Molecular Science of Medicine, Aichi Medical University Yazako, Nagakute, Aichi 480-1195, Japan.

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http://dx.doi.org/10.1093/oxfordjournals.jbchem.a003315DOI Listing
December 2002

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion.

Genes Cells 2002 Apr;7(4):401-12

Division of Molecular Biology, Institute for Molecular and Cellular Biology, Osaka University, 1-3 Yamada-oka, Suita, Osaka 565, Japan.

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April 2002