Jun S Wei

Jun S Wei

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Jun S Wei

Jun S Wei

Publications by authors named "Jun S Wei"

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Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.

Cancer Cell 2017 09;32(3):295-309.e12

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600520PMC
September 2017

Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma.

Genet Med 2017 08 26;19(8):955-958. Epub 2017 Jan 26.

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

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http://www.nature.com/doifinder/10.1038/gim.2016.206
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http://dx.doi.org/10.1038/gim.2016.206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529247PMC
August 2017

Paired Expression Analysis of Tumor Cell Surface Antigens.

Front Oncol 2017 21;7:173. Epub 2017 Aug 21.

Genetics Branch, National Cancer Institute, Center for Cancer Research, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fonc.2017.00173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566986PMC
August 2017

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus.

Cancer Res 2015 Aug 22;75(15):3155-66. Epub 2015 Jun 22.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. The Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526355PMC
August 2015

Clonality and evolutionary history of rhabdomyosarcoma.

PLoS Genet 2015 Mar 13;11(3):e1005075. Epub 2015 Mar 13.

Genetics Branch, Oncogenomics Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Pediatric Oncology Branch, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358975PMC
March 2015

Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.

Cell Rep 2014 Nov 23;9(3):1034-46. Epub 2014 Oct 23.

Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.09.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251494PMC
November 2014

Targeting wild-type and mutationally activated FGFR4 in rhabdomyosarcoma with the inhibitor ponatinib (AP24534).

PLoS One 2013 4;8(10):e76551. Epub 2013 Oct 4.

Oncogenomics Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076551PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790700PMC
May 2014

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.

Cancer Discov 2014 Feb 23;4(2):216-31. Epub 2014 Jan 23.

1Pediatric Oncology Branch, Oncogenomics Section, Center for Cancer Research, NIH; 2Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland; 3Broad Institute of MIT and Harvard, Cambridge; 4Medical Oncology and Center for Cancer Genome Discovery, Dana-Farber Cancer Institute; 5Department of Pathology, Harvard Medical School, Boston, Massachusetts; 6University of Nebraska Medical Center, Omaha, Nebraska; 7Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas; and 8Department of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington; 9The Tumour Bank, The Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia; 10Department of Oncology, Hospital Sant Joan de Deu de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462130PMC
February 2014

Identification of cell surface proteins as potential immunotherapy targets in 12 pediatric cancers.

Front Oncol 2012 17;2:194. Epub 2012 Dec 17.

Immunology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health Bethesda, MD, USA.

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http://dx.doi.org/10.3389/fonc.2012.00194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523547PMC
December 2012

The ezrin metastatic phenotype is associated with the initiation of protein translation.

Neoplasia 2012 Apr;14(4):297-310

Tumor and Metastasis Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349256PMC
http://dx.doi.org/10.1593/neo.11518DOI Listing
April 2012

Synthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastoma.

BMC Cancer 2012 Mar 21;12:101. Epub 2012 Mar 21.

Oncogenomics Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-12-101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364855PMC
March 2012

EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR.

Cancer Res 2012 Jan 8;72(1):315-24. Epub 2011 Nov 8.

Cell & Molecular Biology Section, National Cancer Institute, NIH, Bethesda, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-0961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487161PMC
January 2012

Exon array analysis reveals neuroblastoma tumors have distinct alternative splicing patterns according to stage and MYCN amplification status.

BMC Med Genomics 2011 Apr 18;4:35. Epub 2011 Apr 18.

Oncogenomics Section, Pediatric Oncology Branch, National Cancer Institute, National Institute of Health, Gaithersburg, MD 20877, USA.

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http://dx.doi.org/10.1186/1755-8794-4-35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096898PMC
April 2011

Systematic proteome analysis identifies transcription factor YY1 as a direct target of miR-34a.

J Proteome Res 2011 Feb 23;10(2):479-87. Epub 2010 Dec 23.

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland 20877, USA.

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http://dx.doi.org/10.1021/pr1006697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679541PMC
February 2011

Detection of somatic mutations by high-resolution DNA melting (HRM) analysis in multiple cancers.

PLoS One 2011 Jan 17;6(1):e14522. Epub 2011 Jan 17.

Laboratory of Translational Genomics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014522PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022009PMC
January 2011

Expression profiling identifies epoxy anthraquinone derivative as a DNA topoisomerase inhibitor.

Cancer Lett 2010 Jul 4;293(1):124-31. Epub 2010 Feb 4.

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, MD, USA.

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http://dx.doi.org/10.1016/j.canlet.2010.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698332PMC
July 2010

Global genomic and proteomic analysis identifies biological pathways related to high-risk neuroblastoma.

J Proteome Res 2010 Jan;9(1):373-82

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, 8717 Grovemont Circle, Gaithersburg, Maryland 20877, USA.

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http://dx.doi.org/10.1021/pr900701vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801773PMC
January 2010

Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma.

Cancer Biol Ther 2009 Dec 27;8(24):2386-95. Epub 2009 Dec 27.

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829338PMC
http://dx.doi.org/10.4161/cbt.8.24.10184DOI Listing
December 2009

microRNA profiling identifies cancer-specific and prognostic signatures in pediatric malignancies.

Clin Cancer Res 2009 Sep 25;15(17):5560-8. Epub 2009 Aug 25.

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland 20877, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-3287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737097PMC
September 2009

New Technologies for Diagnosing Pediatric Tumors Expert Opinion on Medical Diagnostics.

Expert Opin Med Diagn 2008 Nov;2(11):1205-1219

Oncogenomic Section, Pediatric Oncology Branch, Advanced Technology Center, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 8717 Grovemont Circle, Bethesda, Maryland 20892-4605, USA.

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http://dx.doi.org/10.1517/17530059.2.11.1205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700769PMC
November 2008

An integrated cross-platform prognosis study on neuroblastoma patients.

Genomics 2008 Oct 30;92(4):195-203. Epub 2008 Jul 30.

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, MD 20877, USA.

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http://dx.doi.org/10.1016/j.ygeno.2008.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562635PMC
October 2008

Whole chromosome alterations predict survival in high-risk neuroblastoma without MYCN amplification.

Clin Cancer Res 2008 Sep;14(17):5540-7

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-07-4461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535913PMC
September 2008

Diagnosis of the small round blue cell tumors using multiplex polymerase chain reaction.

J Mol Diagn 2007 Feb;9(1):80-8

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, 8717 Grovemont Circle, Gaithersburg, MD 20877, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867426PMC
February 2007

Increased WSB1 copy number correlates with its over-expression which associates with increased survival in neuroblastoma.

Genes Chromosomes Cancer 2006 Sep;45(9):856-62

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, 8717 Grovemont Circle, Gaithersburg, MD 20877, USA.

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http://doi.wiley.com/10.1002/gcc.20349
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http://dx.doi.org/10.1002/gcc.20349DOI Listing
September 2006

BBC3 mediates fenretinide-induced cell death in neuroblastoma.

Oncogene 2005 Dec;24(54):7976-83

Pediatric Oncology Branch, National Cancer Institute, 8717 Grovemont Circle, Bethesda, MD 20892-4605, USA.

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http://dx.doi.org/10.1038/sj.onc.1208947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317264PMC
December 2005

Database of mRNA gene expression profiles of multiple human organs.

Genome Res 2005 Mar;15(3):443-50

Advanced Technology Center, Oncogenomics Section, Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Gaithersburg, Maryland 20877, USA.

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http://www.genome.org/cgi/doi/10.1101/gr.3124505
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http://dx.doi.org/10.1101/gr.3124505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC551571PMC
March 2005

Altered expression of cell cycle genes distinguishes aggressive neuroblastoma.

Oncogene 2005 Feb;24(9):1533-41

Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, 8717 Grovemont Circle, Gaithersburg, MD 20877, USA.

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http://dx.doi.org/10.1038/sj.onc.1208341DOI Listing
February 2005