Publications by authors named "Jun Okabe"

27Publications

Targeting Treatment Refractory by EZH2 Inhibition in Postural Tachycardia Syndrome.

Circ Res 2020 Apr 3;126(8):1058-1060. Epub 2020 Mar 3.

From the Epigenetics in Human Health and Disease Laboratory (H.K., A.W.K., J.O., A.E.-O.), Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315654DOI Listing
April 2020

Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart.

iScience 2019 Jul 27;17:288-301. Epub 2019 Jun 27.

Epigenetics in Human Health and Disease, Central Clinical School, Faculty of Medicine, Monash University, Melbourne, VIC 3004, Australia; Baker Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, VIC 3004, Australia; Department of Clinical Pathology, The University of Melbourne, Parkville, VIC 3010, Australia; Hong Kong Institute of Diabetes and Obesity, Prince of Wales Hospital, The Chinese University of Hong Kong, 3/F Lui Che Woo Clinical Sciences Building, 30-32 Ngan Shing Street, Sha Tin, Hong Kong SAR; University College Copenhagen, Faculty of Health, Department of Technology, Biomedical Laboratory Science, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639684PMC
July 2019

Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells.

Mediators Inflamm 2017 12;2017:6909415. Epub 2017 Sep 12.

Department of Comparative and Experimental Medicine, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, Japan.

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http://dx.doi.org/10.1155/2017/6909415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613470PMC
July 2018

Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes.

Epigenetics 2017 ;12(11):991-1003

a Epigenetics in Human Health and Disease Laboratory, Department of Diabetes, Central Clinical School, Faculty of Medicine, Monash University , Melbourne , Victoria , Australia.

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http://dx.doi.org/10.1080/15592294.2017.1371892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788408PMC
December 2018

NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy.

Diabetes 2017 10 26;66(10):2691-2703. Epub 2017 Jul 26.

JDRF Danielle Alberti Memorial Centre for Diabetic Complications, Diabetic Complications Division, Baker IDI Heart and Diabetes Institute, Melbourne, Australia

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http://dx.doi.org/10.2337/db16-1585DOI Listing
October 2017

silencing by in postural tachycardia syndrome.

JCI Insight 2017 03 23;2(6):e90183. Epub 2017 Mar 23.

Central Clinical School, Faculty of Medicine, Monash University, Victoria, Australia.

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http://dx.doi.org/10.1172/jci.insight.90183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358482PMC
March 2017

Current perspectives in Set7 mediated stem cell differentiation.

Noncoding RNA 2016 Dec 4;2(4). Epub 2016 Dec 4.

Epigenetics in Human Health and Disease Laboratory, Baker IDI Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.3390/ncrna2040014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831927PMC
December 2016

Set7 mediated interactions regulate transcriptional networks in embryonic stem cells.

Nucleic Acids Res 2016 Nov 20;44(19):9206-9217. Epub 2016 Jul 20.

Epigenetics in Human Health and Disease Laboratory, Baker IDI Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia

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http://dx.doi.org/10.1093/nar/gkw621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100561PMC
November 2016

Pharmacological inhibition of arginine and lysine methyltransferases induces nuclear abnormalities and suppresses angiogenesis in human endothelial cells.

Biochem Pharmacol 2016 Dec 19;121:18-32. Epub 2016 Sep 19.

Epigenetics in Human Health and Disease Laboratory, Baker IDI Heart & Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia; Epigenomics Profiling Facility, Baker IDI Heart & Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia; Central Clinical School, Faculty of Medicine, Monash University, Victoria, Australia.

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http://dx.doi.org/10.1016/j.bcp.2016.09.013DOI Listing
December 2016

Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling.

Arterioscler Thromb Vasc Biol 2016 Feb 29;36(2):295-307. Epub 2015 Dec 29.

From the Diabetic Complications Laboratory (S.P.G., E.D.M., K.K., P.C., M.E.C., K.A.M.J.-D.), Epigenetics Laboratory (J.O., A.E.-O.), and Diabetes and Dyslipidaemia Group (A.C.C.), Baker IDI Heart and Diabetes Institute, Melbourne, Australia; Faculty of Medicine, Monash University, Melbourne, Australia (S.P.G., E.D.M., K.A.M.J.-D.); Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands (E.A.L.B.); Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom (R.M.T.); and Department of Pharmacology, Cardiovascular Research Institute Maastricht (CARIM), Faculty of Medicine, Health, and Life Science, Maastricht University, Maastricht, The Netherlands (H.H.H.W.S.).

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http://atvb.ahajournals.org/content/36/2/295.full.pdf
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http://atvb.ahajournals.org/lookup/doi/10.1161/ATVBAHA.115.3
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http://dx.doi.org/10.1161/ATVBAHA.115.307012DOI Listing
February 2016

Deep sequencing reveals novel Set7 networks.

Cell Mol Life Sci 2014 Nov 30;71(22):4471-86. Epub 2014 May 30.

Epigenetics in Human Health and Disease Laboratory, Baker IDI Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, VIC, 3004, Australia.

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http://dx.doi.org/10.1007/s00018-014-1651-yDOI Listing
November 2014

Endothelial transcriptome in response to pharmacological methyltransferase inhibition.

ChemMedChem 2014 Aug 21;9(8):1755-62. Epub 2014 May 21.

Epigenetics in Human Health & Disease Laboratory, Baker IDI Heart & Diabetes Institute, The Alfred Medical Research & Education Precinct, Melbourne, Victoria 3004 (Australia); Faculty of Medicine, Nursing & Health Sciences, Monash University, Victoria 3800 (Australia).

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http://dx.doi.org/10.1002/cmdc.201402091DOI Listing
August 2014

Vascular histone deacetylation by pharmacological HDAC inhibition.

Genome Res 2014 Aug 14;24(8):1271-84. Epub 2014 Apr 14.

Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria 3010, Australia; Faculty of Medicine, Monash University, Victoria 3800, Australia

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http://dx.doi.org/10.1101/gr.168781.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120081PMC
August 2014

Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy.

J Am Soc Nephrol 2014 Jun 7;25(6):1237-54. Epub 2014 Feb 7.

Diabetic Complications Division, Juvenile Diabetes Research Foundation Danielle Alberti Memorial Centre for Diabetic Complications, Baker IDI Heart & Diabetes Institute, Melbourne, Victoria, Australia; Department of Medicine, Monash University, Melbourne, Victoria, Australia;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033375PMC
http://dx.doi.org/10.1681/ASN.2013070810DOI Listing
June 2014

The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart.

Nucleic Acids Res 2014 Jan 16;42(2):790-803. Epub 2013 Oct 16.

Epigenetics in Human Health and Disease Laboratory, The Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia, Experimental Cardiology, Baker IDI Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia and Central Clinical School, Faculty of Medicine, Monash University, Victoria, Australia.

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http://dx.doi.org/10.1093/nar/gkt896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902903PMC
January 2014

Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation.

FASEB J 2013 Dec 4;27(12):4940-53. Epub 2013 Sep 4.

1Department of Comparative and Experimental Medicine, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan.

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http://dx.doi.org/10.1096/fj.13-233528DOI Listing
December 2013

Distinguishing hyperglycemic changes by Set7 in vascular endothelial cells.

Circ Res 2012 Apr 8;110(8):1067-76. Epub 2012 Mar 8.

Epigenetics in Human Health and Disease Laboratory, Baker IDI Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1161/CIRCRESAHA.112.266171DOI Listing
April 2012

Epigenetic phenomena linked to diabetic complications.

Nat Rev Endocrinol 2010 Dec 2;6(12):665-75. Epub 2010 Nov 2.

Epigenetics in Human Health and Disease Laboratory, The Alfred Medical Research and Education Precinct, Baker IDI Heart and Diabetes Institute, 5th Floor, 75 Commercial Road, Melbourne, VIC 3004, Australia.

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http://dx.doi.org/10.1038/nrendo.2010.188DOI Listing
December 2010

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes.

Aging (Albany NY) 2010 Oct;2(10):659-68

Baker IDI Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993796PMC
http://dx.doi.org/10.18632/aging.100203DOI Listing
October 2010

Iron-catalyzed, directed oxidative arylation of olefins with organozinc and Grignard reagents.

Org Lett 2010 Jun;12(12):2838-40

Department of Chemistry, School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1021/ol1009448DOI Listing
June 2010

Limited capacity of the nuclear matrix to bind telomere repeat binding factor TRF1 may restrict the proliferation of mortal human fibroblasts.

Hum Mol Genet 2004 Feb 17;13(3):285-93. Epub 2003 Dec 17.

Gene Function Research Center, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8562, Japan.

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http://dx.doi.org/10.1093/hmg/ddh032DOI Listing
February 2004

Basic peptides as functional components of non-viral gene transfer vehicles.

Curr Protein Pept Sci 2003 Apr;4(2):141-50

Gene Function Research Laboratory, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, 305-8562, Japan.

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http://dx.doi.org/10.2174/1389203033487234DOI Listing
April 2003