Jun Ohashi

Jun Ohashi

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Interferon lambda 1 is associated with dengue severity in Thailand.

Int J Infect Dis 2020 Jan 22. Epub 2020 Jan 22.

Department of Parasitology and Entomology, Faculty of Public Health, Mahidol University, Ratchawithi Road, Bangkok 10400, Thailand. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2020.01.026DOI Listing
January 2020

Analysis of whole Y-chromosome sequences reveals the Japanese population history in the Jomon period.

Sci Rep 2019 Jun 17;9(1):8556. Epub 2019 Jun 17.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1038/s41598-019-44473-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572846PMC
June 2019

Human Biology of Japan.

Ann Hum Biol 2019 Jun;46(4):285-286

Department of Biological Sciences, Graduate School of Science, The University of Tokyo , Tokyo , Japan.

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http://dx.doi.org/10.1080/03014460.2019.1671675DOI Listing
June 2019

microRNA-27a and microRNA-146a SNP in cerebral malaria.

Mol Genet Genomic Med 2019 02 1;7(2):e00529. Epub 2019 Jan 1.

Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1002/mgg3.529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393659PMC
February 2019

Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea.

Sci Rep 2018 04 3;8(1):5565. Epub 2018 Apr 3.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1038/s41598-018-23811-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882878PMC
April 2018

Mitochondrial DNA variations in Austronesian-speaking populations living in the New Georgia Islands, the Western Province of the Solomon Islands.

J Hum Genet 2018 Jan 13;63(1):101-104. Epub 2017 Nov 13.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1038/s10038-017-0372-0DOI Listing
January 2018

A missense variant, rs373863828-A (p.Arg457Gln), of CREBRF and body mass index in Oceanic populations.

J Hum Genet 2017 Sep 13;62(9):847-849. Epub 2017 Apr 13.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2017.44DOI Listing
September 2017

Evidence for Very Recent Positive Selection in Mongolians.

Mol Biol Evol 2017 08;34(8):1936-1946

Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Japan.

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http://dx.doi.org/10.1093/molbev/msx138DOI Listing
August 2017

Evolution of Fseg/Cseg dimorphism in region III of the Plasmodium falciparum eba-175 gene.

Infect Genet Evol 2017 04 27;49:251-255. Epub 2017 Jan 27.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15671348173002
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http://dx.doi.org/10.1016/j.meegid.2017.01.026DOI Listing
April 2017

Elucidating the origin of HLA-B*73 allelic lineage: Did modern humans benefit by archaic introgression?

Immunogenetics 2017 Jan 30;69(1):63-67. Epub 2016 Sep 30.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1007/s00251-016-0952-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203853PMC
January 2017

Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection.

J Med Virol 2017 01 6;89(1):123-129. Epub 2016 Jul 6.

Center for AIDS Research, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1002/jmv.24612DOI Listing
January 2017

Association of PECAM1/CD31 polymorphisms with cerebral malaria.

Int J Mol Epidemiol Genet 2016 1;7(2):87-94. Epub 2016 Jun 1.

Faculty of Tropical Medicine, Mahidol University Bangkok, Thailand.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913224PMC
June 2016

Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system.

Sci Rep 2016 Jan 27;6:19675. Epub 2016 Jan 27.

RIKEN Brain Science Institute, Wako, Saitama, Japan.

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http://dx.doi.org/10.1038/srep19675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728555PMC
January 2016

Human immune system diversity and its implications in diseases.

J Hum Genet 2015 Nov;60(11):655-6

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2015.101DOI Listing
November 2015

Genetic evidence for contribution of human dispersal to the genetic diversity of EBA-175 in Plasmodium falciparum.

Malar J 2015 Aug 1;14:293. Epub 2015 Aug 1.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1186/s12936-015-0820-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522064PMC
August 2015

Lack of association between BSG polymorphisms and cerebral malaria.

Jpn J Infect Dis 2014 ;67(6):432-5

Faculty of Medicine, University of Tsukuba.

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http://dx.doi.org/10.7883/yoken.67.432DOI Listing
July 2015

Diversifying selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium falciparum in Thailand.

PLoS One 2014 28;9(2):e90522. Epub 2014 Feb 28.

Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090522PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938765PMC
June 2015

Insulin administration may trigger type 1 diabetes in Japanese type 2 diabetes patients with type 1 diabetes high-risk HLA class II and the insulin gene VNTR genotype.

J Clin Endocrinol Metab 2014 Sep 27;99(9):E1793-7. Epub 2014 Jun 27.

Department of Diabetes and Molecular Genetics (W.N., R.K., H.On., H.Os., H.M.), Ehime University Graduate School of Medicine, To-on, Ehime 791-0295, Japan; Department of Internal Medicine (M.N.), Kokogawa W City Hospital, Hyogo 675-8611, Japan; Department of Metabolic Medicine (A.I.), Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan; Department of Internal Medicine (I) (T.H.), Osaka Medical College, Osaka 569-8686, Japan; University of Tsukuba (J.O.), Ibaraki, Japan; 6) Division of Diabetes (K.T.), Department of Internal Medicine, Kurashiki Central Hospital, Kurashiki 710-8602, Japan; Department of Diabetes (T.S.), Kochi Takasu Hospital, Kochi 781-5103, Japan; Sumitomo Hospital (Y.Y.), Osaka 530-0005, Japan; Diabetes Research Center (D.C.), National Center for Global Health and Medicine, Tokyo 162-8655, Japan; Department of Metabolism/Diabetes and Clinical Nutrition (E.K.), Nagasaki University Hospital, Nagasaki 852-8501, Japan; and Shiraishi Hospital Diabetes Center (H.M.), Imabari, Ehime 794-0041, Japan.

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http://dx.doi.org/10.1210/jc.2014-1759DOI Listing
September 2014

Generation of rodent malaria parasites with a high mutation rate by destructing proofreading activity of DNA polymerase δ.

DNA Res 2014 Aug 25;21(4):439-46. Epub 2014 Mar 25.

Laboratory of Malariology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan

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http://dx.doi.org/10.1093/dnares/dsu009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131837PMC
August 2014

Ordered accumulation of mutations conferring resistance to sulfadoxine-pyrimethamine in the Plasmodium falciparum parasite.

J Infect Dis 2014 Jan 6;209(1):130-9. Epub 2013 Aug 6.

Department of Molecular and Cellular Parasitology, Juntendo University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1093/infdis/jit415DOI Listing
January 2014

MxA transcripts with distinct first exons and modulation of gene expression levels by single-nucleotide polymorphisms in human bronchial epithelial cells.

Immunogenetics 2013 Feb 18;65(2):107-14. Epub 2012 Nov 18.

Department of Respiratory Diseases, Research Institute, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00251-012-0663-8DOI Listing
February 2013

High frequency of HLA B62 in fulminant type 1 diabetes with the drug-induced hypersensitivity syndrome.

J Clin Endocrinol Metab 2012 Dec 15;97(12):E2277-81. Epub 2012 Oct 15.

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, To-on, Ehime, 791-0295 Japan.

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http://dx.doi.org/10.1210/jc.2012-2054DOI Listing
December 2012

Association of IFNGR2 gene polymorphisms with pulmonary tuberculosis among the Vietnamese.

Hum Genet 2012 May 6;131(5):675-82. Epub 2011 Nov 6.

Department of Respiratory Diseases, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.

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http://dx.doi.org/10.1007/s00439-011-1112-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325415PMC
May 2012

No evidence for strong recent positive selection favoring the 7 repeat allele of VNTR in the DRD4 gene.

PLoS One 2011 31;6(8):e24410. Epub 2011 Aug 31.

Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024410PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164202PMC
January 2012

Association of ADAMTS13 polymorphism with cerebral malaria.

Malar J 2011 Dec 14;10:366. Epub 2011 Dec 14.

Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1186/1475-2875-10-366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261218PMC
December 2011

The serum leptin level and body mass index in Melanesian and Micronesian Solomon Islanders: focus on genetic factors and urbanization.

Am J Hum Biol 2011 Jul-Aug;23(4):435-44. Epub 2010 Dec 17.

Network for Education and Research on Asia, The University of Tokyo, Institute for Advanced Studies on Asia, The University of Tokyo, Japan.

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http://doi.wiley.com/10.1002/ajhb.21124
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http://dx.doi.org/10.1002/ajhb.21124DOI Listing
October 2011

Cumulative association of eight susceptibility genes with systemic lupus erythematosus in a Japanese female population.

J Hum Genet 2011 Jul 12;56(7):503-7. Epub 2011 May 12.

Molecular and Genetic Epidemiology Laboratory, Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1038/jhg.2011.49DOI Listing
July 2011

Molecular cloning of two novel mucin-like genes in the disease-susceptibility locus for diffuse panbronchiolitis.

Hum Genet 2011 Feb 28;129(2):117-28. Epub 2010 Oct 28.

Department of Respiratory Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.

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http://dx.doi.org/10.1007/s00439-010-0906-4DOI Listing
February 2011

The impact of natural selection on an ABCC11 SNP determining earwax type.

Mol Biol Evol 2011 Jan 11;28(1):849-57. Epub 2010 Oct 11.

Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1093/molbev/msq264DOI Listing
January 2011

IFNGR1 polymorphisms in Thai malaria patients.

Infect Genet Evol 2009 Dec 25;9(6):1406-9. Epub 2009 Aug 25.

Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1016/j.meegid.2009.08.004DOI Listing
December 2009

Mapping human genetic diversity in Asia.

Science 2009 Dec;326(5959):1541-5

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http://dx.doi.org/10.1126/science.1177074DOI Listing
December 2009

Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria.

Malar J 2009 Oct 19;8:232. Epub 2009 Oct 19.

Doctoral Programme in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1186/1475-2875-8-232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770543PMC
October 2009

The absolute counting of red cell-derived microparticles with red cell bead by flow rate based assay.

Cytometry B Clin Cytom 2009 May;76(3):191-8

Department of Medical Technology, Faculty of Allied Health Science, Naresuan University, Phitsanulok, Thailand.

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http://dx.doi.org/10.1002/cyto.b.20465DOI Listing
May 2009

A practical case-control association test for detecting a susceptibility allele at a copy number variation locus.

Authors:
Jun Ohashi

J Hum Genet 2009 Mar 6;54(3):169-73. Epub 2009 Feb 6.

Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.

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http://www.nature.com/articles/jhg20098
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http://dx.doi.org/10.1038/jhg.2009.8DOI Listing
March 2009

Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.

Arthritis Res Ther 2008 19;10(5):R113. Epub 2008 Sep 19.

Molecular and Genetic Epidemiology Laboratory, Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.

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http://dx.doi.org/10.1186/ar2516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592800PMC
February 2009

Lack of association of the HbE variant with protection from cerebral malaria in Thailand.

Biochem Genet 2008 Dec 12;46(11-12):708-11. Epub 2008 Sep 12.

Department of Human Genetics, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1007/s10528-008-9185-3DOI Listing
December 2008

Linkage disequilibrium structure of the 5q31-33 region in a Thai population.

J Hum Genet 2008 24;53(9):850-856. Epub 2008 Jun 24.

Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1007/s10038-008-0309-8DOI Listing
November 2008

Appropriate data cleaning methods for genome-wide association study.

J Hum Genet 2008 12;53(10):886-893. Epub 2008 Aug 12.

Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1007/s10038-008-0322-yDOI Listing
November 2008

Association and interaction analyses of NRG1 and ERBB4 genes with schizophrenia in a Japanese population.

J Hum Genet 2008 14;53(10):929-935. Epub 2008 Aug 14.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan.

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http://www.nature.com/doifinder/10.1007/s10038-008-0332-9
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http://dx.doi.org/10.1007/s10038-008-0332-9DOI Listing
November 2008

Association study of the 15q11-q13 maternal expression domain in Japanese autistic patients.

Am J Med Genet B Neuropsychiatr Genet 2008 Oct;147B(7):1008-12

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan.

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http://dx.doi.org/10.1002/ajmg.b.30690DOI Listing
October 2008

A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia.

Hum Genet 2008 Sep 13;124(2):179-85. Epub 2008 Aug 13.

Data Analysis Fusion Team, Computational Science Research Program, RIKEN, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00439-008-0537-1DOI Listing
September 2008

Gene flow and natural selection in oceanic human populations inferred from genome-wide SNP typing.

Mol Biol Evol 2008 Aug 3;25(8):1750-61. Epub 2008 Jun 3.

Department of Forensic Medicine, Tokai University School of Medicine, Kanagawa, Japan.

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http://dx.doi.org/10.1093/molbev/msn128DOI Listing
August 2008

Serum resistin is positively correlated with the accumulation of metabolic syndrome factors in type 2 diabetes.

Clin Endocrinol (Oxf) 2008 Jul 1;69(1):74-80. Epub 2008 Jul 1.

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, Ehime Prefectural Hospital, Ehime, Japan.

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http://doi.wiley.com/10.1111/j.1365-2265.2007.03154.x
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http://dx.doi.org/10.1111/j.1365-2265.2007.03154.xDOI Listing
July 2008

No association between the ryanodine receptor 3 gene and autism in a Japanese population.

Psychiatry Clin Neurosci 2008 Jun;62(3):341-4

Department of Neuropsychiatry, Graduate School of Medicine, Univerisity of Tokyo, Bunkyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1440-1819.2008.01802.xDOI Listing
June 2008

Serum resistin is reduced by glucose and meal loading in healthy human subjects.

Metabolism 2008 Feb;57(2):149-56

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.metabol.2007.08.018DOI Listing
February 2008

Distribution of HLA alleles and haplotypes in Jinuo and Wa populations in Southwest China.

Hum Immunol 2008 Jan 26;69(1):58-65. Epub 2007 Dec 26.

Institute of Medical Biology, Chinese Academy of Medical Sciences, Kunming, China.

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http://dx.doi.org/10.1016/j.humimm.2007.11.007DOI Listing
January 2008