Jun Ishihara

Jun Ishihara

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Jun Ishihara

Jun Ishihara

Publications by authors named "Jun Ishihara"

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New entry to the enantioselective formation of substituted cyclohexenes bearing an all-carbon quaternary stereogenic center.

Chirality 2020 03 20;32(3):273-281. Epub 2020 Jan 20.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.

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http://dx.doi.org/10.1002/chir.23173DOI Listing
March 2020

Establishment of Novel High-Standard Chemiluminescent Assay for NTPase in Two Protozoans and Its High-Throughput Screening.

Mar Drugs 2020 Mar 13;18(3). Epub 2020 Mar 13.

Center for Therapeutic Innovation, Gene Research Center for Frontiers Life Sciences, Nagasaki University, Graduate School of Biomedical Sciences, 1-12-14 Sakamoto, Nagasaki 852-8523, Japan.

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http://dx.doi.org/10.3390/md18030161DOI Listing
March 2020

Novel Reporter System Monitoring IL-18 Specific Signaling Can Be Applied to High-Throughput Screening.

Mar Drugs 2020 Jan 17;18(1). Epub 2020 Jan 17.

Center for Therapeutic Innovation, Gene Research Center for Frontiers Life Sciences, Nagasaki University, Graduate School of Biomedical Sciences, 1-12-14 Sakamoto, Nagasaki 852-8523-0022, Japan.

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http://dx.doi.org/10.3390/md18010060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024245PMC
January 2020

A neonatal case of HDR syndrome and a vascular ring with a novel mutation.

Hum Genome Var 2019 23;6:55. Epub 2019 Dec 23.

2Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo Japan.

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http://dx.doi.org/10.1038/s41439-019-0087-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928020PMC
December 2019

Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies.

Sci Adv 2019 11 6;5(11):eaay1971. Epub 2019 Nov 6.

Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1126/sciadv.aay1971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834392PMC
November 2019

Anti-myelin Oligodendrocyte Glycoprotein Antibody-positive Optic Neuritis in a Girl With Ulcerative Colitis.

J Pediatr Gastroenterol Nutr 2019 Oct;69(4):e117

Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume.

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http://dx.doi.org/10.1097/MPG.0000000000002281DOI Listing
October 2019

Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy.

Sci Adv 2019 08 14;5(8):eaaw6081. Epub 2019 Aug 14.

Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1126/sciadv.aaw6081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693903PMC
August 2019

Laboratory values in Japanese children with newly diagnosed inflammatory bowel disease.

Pediatr Int 2019 Jul;61(7):720-725

Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, Japan.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13892
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http://dx.doi.org/10.1111/ped.13892DOI Listing
July 2019

Total Synthesis of Lajollamycin B.

Chemistry 2019 Jun 15;25(33):7927-7934. Epub 2019 May 15.

Medical Innovation Center, Nagasaki University, Bunkyo-machi, Nagasaki, 852-8521, Japan.

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http://dx.doi.org/10.1002/chem.201901069DOI Listing
June 2019

Synthetic Studies on Spirolides A and B: Formation of the Upper Carbon Framework Based on a Lewis Acid Template-Catalyzed Diels-Alder Reaction.

Chemistry 2019 Jan 20;25(6):1543-1552. Epub 2018 Dec 20.

Medical Innovation Center, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki, 852-8521, Japan.

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http://doi.wiley.com/10.1002/chem.201804977
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http://dx.doi.org/10.1002/chem.201804977DOI Listing
January 2019

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.

Mol Cancer Ther 2018 11 10;17(11):2399-2411. Epub 2018 Aug 10.

Institute for Molecular Engineering, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0091DOI Listing
November 2018

Ionic Liquid-Mediated Hydrofluorination of o-Azaxylylenes Derived from 3-Bromooxindoles.

Org Lett 2017 05 28;19(10):2572-2575. Epub 2017 Apr 28.

Nishiisahaya Hospital , 3015 Kaizu, Isahaya, Nagasaki 854-0063, Japan.

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http://dx.doi.org/10.1021/acs.orglett.7b00887DOI Listing
May 2017

Unified synthesis of tirandamycins and streptolydigins.

Chem Commun (Camb) 2015 Dec;51(95):17004-7

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1039/c5cc07749dDOI Listing
December 2015

Total Synthesis of (-)-N-Methylwelwitindolinone C Isothiocyanate Based on a Pd-Catalyzed Tandem Enolate Coupling Strategy.

Org Lett 2015 Aug 27;17(15):3918-21. Epub 2015 Jul 27.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/acs.orglett.5b01952DOI Listing
August 2015

Stripe-patterned thermo-responsive cell culture dish for cell separation without cell labeling.

Small 2015 Feb 19;11(6):681-7. Epub 2014 Sep 19.

Institute of Advanced Biomedical Engineering and Science (TWIns), Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

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http://dx.doi.org/10.1002/smll.201400787DOI Listing
February 2015

Lewis acid template-catalyzed asymmetric diels-alder reaction.

J Org Chem 2015 Feb 29;80(4):2037-41. Epub 2015 Jan 29.

Graduate School of Biomedical Sciences, Nagasaki University , 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/acs.joc.5b00055DOI Listing
February 2015

Total synthesis of marinomycin A based on a direct dimerization strategy.

Angew Chem Int Ed Engl 2014 Aug 24;53(32):8459-62. Epub 2014 Jun 24.

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521 (Japan).

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http://dx.doi.org/10.1002/anie.201404408DOI Listing
August 2014

Total synthesis of oxazolomycins.

Chem Rec 2014 Aug 28;14(4):663-77. Epub 2014 Jul 28.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, 852-8521, Japan.

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http://dx.doi.org/10.1002/tcr.201402009DOI Listing
August 2014

The absolute configuration for inthomycin C: revision of previously published work with a reinstatement of the (3R)-configuration for (-)-inthomycin C.

Org Lett 2014 Jul 24;16(13):3536-9. Epub 2014 Jun 24.

The School of Chemistry and Chemical Engineering and the Centre for Cancer Research and Cell Biology (CCRCB), The Queen's University Belfast , Stranmillis Road, Belfast BT9 5AG, Northern Ireland, United Kingdom.

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http://dx.doi.org/10.1021/ol501484tDOI Listing
July 2014

Total synthesis of (-)-dihydrosporothriolide utilizing an indium-mediated Reformatsky-Claisen rearrangement.

J Org Chem 2014 Jun 11;79(12):5908-13. Epub 2014 Jun 11.

Graduate School of Biomedical Sciences, Nagasaki University , 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/jo5008948DOI Listing
June 2014

A role for c-Kit in the maintenance of undifferentiated human mesenchymal stromal cells.

Biomaterials 2014 Apr 24;35(11):3618-26. Epub 2014 Jan 24.

Section of Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan; Global Center of Excellence Program, International Research Center for Molecular Science in Tooth and Bone Diseases (GCOE Program), Tokyo Medical and Dental University, Japan.

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http://dx.doi.org/10.1016/j.biomaterials.2014.01.031DOI Listing
April 2014

Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3.

Int J Hematol 2014 Apr 22;99(4):393-406. Epub 2014 Feb 22.

Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan.

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http://dx.doi.org/10.1007/s12185-014-1534-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412171PMC
April 2014

Formal [4 + 1]-cycloaddition of homopropargyl alcohols to diazo dicarbonyl compounds giving substituted tetrahydrofurans.

Org Lett 2014 Feb 13;16(3):1004-7. Epub 2014 Jan 13.

Graduate School of Biomedical Sciences, Nagasaki University , Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/ol403746rDOI Listing
February 2014

Total synthesis of (-)-ophiodilactone A and (-)-ophiodilactone B.

Angew Chem Int Ed Engl 2014 Jan 11;53(3):757-60. Epub 2013 Dec 11.

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521 (Japan).

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http://dx.doi.org/10.1002/anie.201307835DOI Listing
January 2014

Pediatric mumps with laryngeal edema.

Pediatr Emerg Care 2013 Oct;29(10):1104-6

From the Departments of *Pediatrics, and †Emergency Medicine, Yokohama Municipal Citizen's Hospital, Yokohama, Kanagawa, Japan.

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http://dx.doi.org/10.1097/PEC.0b013e3182a60049DOI Listing
October 2013

Young athlete with sudden cardiac arrest treated with therapeutic hypothermia.

Pediatr Int 2013 Oct;55(5):e123-5

Department of Pediatrics, Yokohama Municipal Citizen's Hospital, Yokohama, Kanagawa, Japan.

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http://dx.doi.org/10.1111/ped.12144DOI Listing
October 2013

Total synthesis of (-)-cinatrin C1 based on an In(OTf)3-catalyzed Conia-Ene reaction.

J Org Chem 2013 Apr 11;78(8):3847-57. Epub 2013 Apr 11.

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/jo400263wDOI Listing
April 2013

A new method for the protection of carboxylic acids with a triisopropylsiloxymethyl group.

Chem Pharm Bull (Tokyo) 2012 ;60(10):1334-9

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1248/cpb.c12-00490DOI Listing
March 2013

Recent developments in the Reformatsky-Claisen rearrangement.

Molecules 2012 Nov 30;17(12):14249-59. Epub 2012 Nov 30.

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.3390/molecules171214249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268371PMC
November 2012

Organocatalytic asymmetric syntheses of inthomycins A, B and C.

Org Biomol Chem 2012 Oct;10(40):8164-74

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-Machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1039/c2ob26084kDOI Listing
October 2012

Stereocontrolled total synthesis of (-)-englerin A.

J Org Chem 2012 Sep 17;77(17):7364-70. Epub 2012 Aug 17.

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/jo301145rDOI Listing
September 2012

Total synthesis of (-)-kaitocephalin based on a Rh-catalyzed C-H amination.

Org Lett 2012 Mar 5;14(6):1644-7. Epub 2012 Mar 5.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, 852-8521, Japan.

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http://dx.doi.org/10.1021/ol300431nDOI Listing
March 2012

Total synthesis of oxazolomycin A.

Org Lett 2011 Oct 2;13(19):5398-401. Epub 2011 Sep 2.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/ol202306dDOI Listing
October 2011

Total synthesis of NW-G01, a cyclic hexapeptide antibiotic, and 34-epi-NW-G01.

Org Lett 2011 Sep 2;13(17):4700-3. Epub 2011 Aug 2.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, 852-8521, Japan.

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http://dx.doi.org/10.1021/ol201912wDOI Listing
September 2011

Ectopic calcification as discernible manifestation in neonates with pseudohypoparathyroidism type 1a.

Int J Endocrinol 2009 ;2009:931057

Department of Endocrinology & Metabolism, Clinical Research Institute, Kanagawa Children's Medical Center, Yokohama 232-8555, Japan.

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http://dx.doi.org/10.1155/2009/931057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778176PMC
July 2011

Clinical efficacy of a novel elimination diet composed of a mixture of amino acids and potatoes in dogs with non-seasonal pruritic dermatitis.

J Vet Med Sci 2010 Nov 25;72(11):1413-21. Epub 2010 Jun 25.

First Department of Veterinary Microbiology, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.

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http://dx.doi.org/10.1292/jvms.10-0014DOI Listing
November 2010

Synthesis and preliminary biological evaluation of 20-epi-eldecalcitol [20-epi-1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3: 20-epi-ED-71].

J Steroid Biochem Mol Biol 2010 Jul 18;121(1-2):25-8. Epub 2010 Mar 18.

Graduate School of Biomedical Sciences, Nagasaki University, 1-14, Bunkyomachi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1016/j.jsbmb.2010.03.041DOI Listing
July 2010

Enantio- and stereoselective route to the phoslactomycin family of antibiotics: formal synthesis of (+)-fostriecin and (+)-phoslactomycin B.

Chem Commun (Camb) 2009 Oct 10(39):5907-9. Epub 2009 Aug 10.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1039/b912267bDOI Listing
October 2009

Entry to heterocycles based on indium-catalyzed conia-ene reactions: asymmetric synthesis of (-)-salinosporamide A.

Angew Chem Int Ed Engl 2008 ;47(33):6244-6

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bnkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1002/anie.200801967DOI Listing
September 2008

Asymmetric total synthesis of (+)-phoslactomycin B.

Org Lett 2008 Jun 8;10(11):2139-42. Epub 2008 May 8.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.

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http://dx.doi.org/10.1021/ol8004672DOI Listing
June 2008

Total synthesis of neooxazolomycin.

Angew Chem Int Ed Engl 2007 ;46(35):6703-5

Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1002/anie.200702229DOI Listing
October 2007

A highly stereocontrolled total synthesis of dysiherbaine.

Chem Commun (Camb) 2007 Oct 6(40):4158-60. Epub 2007 Aug 6.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1039/b709627eDOI Listing
October 2007

Synthesis and biological evaluation of a 3-positon epimer of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71).

J Steroid Biochem Mol Biol 2007 Mar 5;103(3-5):222-6. Epub 2007 Jan 5.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1016/j.jsbmb.2006.12.025DOI Listing
March 2007

Beta-isocupreidine-catalyzed Baylis-Hillman reaction of chiral N-boc-alpha-amino aldehydes.

Org Lett 2006 Nov;8(23):5357-60

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki-852-8521, Japan.

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http://dx.doi.org/10.1021/ol0622561DOI Listing
November 2006

Synthesis of putative metabolites of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D(3) (ED-71).

Steroids 2006 Jul 25;71(7):529-40. Epub 2006 Apr 25.

Chemistry Research Department I, Chugai Pharmaceutical Co., Ltd., 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.

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http://dx.doi.org/10.1016/j.steroids.2005.11.001DOI Listing
July 2006

A highly stereocontrolled total synthesis of (-)-neodysiherbaine A.

J Org Chem 2006 May;71(11):4227-31

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/jo060410rDOI Listing
May 2006

Total synthesis of (+)-beta-erythroidine.

Angew Chem Int Ed Engl 2006 Apr;45(17):2731-4

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1002/anie.200600210DOI Listing
April 2006

Total synthesis of viridiofungin A.

Chem Commun (Camb) 2005 May 9(17):2265-7. Epub 2005 Mar 9.

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1039/b500660kDOI Listing
May 2005

A concise route to (+)-lactacystin.

J Org Chem 2004 Oct;69(22):7765-8

Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

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http://dx.doi.org/10.1021/jo048817oDOI Listing
October 2004

Time interval of measles vaccination in patients with Kawasaki disease treated with additional intravenous immune globulin.

Eur J Pediatr 2004 Jan 18;163(1):25-9. Epub 2003 Nov 18.

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.

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http://link.springer.com/10.1007/s00431-003-1335-3
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http://dx.doi.org/10.1007/s00431-003-1335-3DOI Listing
January 2004

Studies aimed at the total synthesis of azadirachtin. A modeled connection of C-8 and C-14 in azadirachtin.

Org Lett 2002 Aug;4(17):2877-80

Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan.

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http://dx.doi.org/10.1021/ol026260yDOI Listing
August 2002

Total Synthesis of (-)-Verrucarol(1).

J Org Chem 1998 Apr;63(8):2679-2688

Department of Applied Chemistry, Keio University, Hiyoshi, Kohoku-ku, Yokohama 223, Japan.

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http://dx.doi.org/10.1021/jo972309fDOI Listing
April 1998