Julio Martin

Julio Martin

UNVERIFIED PROFILE

Are you Julio Martin?   Register this Author

Register author
Julio Martin

Julio Martin

Publications by authors named "Julio Martin"

Are you Julio Martin?   Register this Author

55Publications

949Reads

45Profile Views

The Q Site of Cytochrome is a Promiscuous Drug Target in and .

ACS Infect Dis 2020 Mar 30;6(3):515-528. Epub 2020 Jan 30.

Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsinfecdis.9b00426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076694PMC
March 2020

Identification of Small Molecules Disrupting the Ubiquitin Proteasome System in Malaria.

ACS Infect Dis 2019 12 7;5(12):2105-2117. Epub 2019 Nov 7.

Tres Cantos Medicines Development Campus, Diseases of the Developing World . GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , 28760 Madrid , Spain.

View Article

Download full-text PDF

Source
https://pubs.acs.org/doi/10.1021/acsinfecdis.9b00216
Publisher Site
http://dx.doi.org/10.1021/acsinfecdis.9b00216DOI Listing
December 2019

The differential diagnoses of uterine leiomyomas and leiomyosarcomas using DNA and RNA sequencing.

Am J Obstet Gynecol 2019 10 20;221(4):320.e1-320.e23. Epub 2019 May 20.

Igenomix Foundation-Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain; Department of Pediatrics, Obstetrics and Gynecology, School of Medicine, University of Valencia, Valencia, Spain; Department of Obstetrics and Gynecology, School of Medicine, Stanford University, Stanford, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2019.05.018DOI Listing
October 2019

Novel chemical starting points for drug discovery in leishmaniasis and Chagas disease.

Int J Parasitol Drugs Drug Resist 2019 08 22;10:58-68. Epub 2019 May 22.

Calibr at Scripps Research, La Jolla, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpddr.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545338PMC
August 2019

Relative Contributions of and Bacteriophage to Bacterial Cell Death under Various Environmental Conditions.

mBio 2018 08 7;9(4). Epub 2018 Aug 7.

School of the Environment, Florida Agricultural and Mechanical University, Tallahassee, Florida, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/mBio.01202-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083911PMC
August 2018

Complex Interplay between Sphingolipid and Sterol Metabolism Revealed by Perturbations to the Leishmania Metabolome Caused by Miltefosine.

Antimicrob Agents Chemother 2018 05 26;62(5). Epub 2018 Apr 26.

Centre for Metabolomics and Bioanalysis (CEMBIO), Facultad de Farmacia, Universidad CEU San Pablo, Campus Montepríncipe, Boadilla del Monte, Madrid, Spain

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02095-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923112PMC
May 2018

Metabolic Clustering Analysis as a Strategy for Compound Selection in the Drug Discovery Pipeline for Leishmaniasis.

ACS Chem Biol 2018 05 24;13(5):1361-1369. Epub 2018 Apr 24.

Centre for Metabolomics and Bioanalysis (CEMBIO) , Facultad de Farmacia, Universidad CEU San Pablo , Campus Montepríncipe, Boadilla del Monte , 28668 Madrid , Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschembio.8b00204DOI Listing
May 2018

Efforts Aimed To Reduce Attrition in Antimalarial Drug Discovery: A Systematic Evaluation of the Current Antimalarial Targets Portfolio.

ACS Infect Dis 2018 04 24;4(4):568-576. Epub 2018 Jan 24.

Tres Cantos Medicines Development Campus, DDW , GlaxoSmithKline , Severo Ochoa, 2 , 28760 Tres Cantos , Madrid , Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsinfecdis.7b00211DOI Listing
April 2018

Unravelling the rate of action of hits in the Leishmania donovani box using standard drugs amphotericin B and miltefosine.

PLoS Negl Trop Dis 2017 May 25;11(5):e0005629. Epub 2017 May 25.

Kinetoplastids DPU, Diseases of the Developing World (DDW), GlaxoSmithKline, Tres Cantos, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0005629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462473PMC
May 2017

A Replicative In Vitro Assay for Drug Discovery against Leishmania donovani.

Antimicrob Agents Chemother 2016 06 23;60(6):3524-32. Epub 2016 May 23.

Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.01781-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879429PMC
June 2016

Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology.

Fertil Steril 2015 Nov 3;104(5):1286-93. Epub 2015 Sep 3.

IGenomix, Parc Cientific Univeristat Valencia, Valencia, Spain; Instituto Valenciano de Infertilidad Valencia and Fundación Instituto Valenciano de Infertilidad, Valencia, Spain; Department of Obstetrics and Gynecology, Valencia University, Instituto Universitario IVI/INCLIVA, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fertnstert.2015.07.1166DOI Listing
November 2015

Core muscle activity in a series of balance exercises with different stability conditions.

Gait Posture 2015 Jul 27;42(2):186-92. Epub 2015 May 27.

Research Group in Sport and Health, Department of Physical Education and Sports, University of Valencia, Valencia, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gaitpost.2015.05.008DOI Listing
July 2015

Psychological Intervention in Primary Care After Earthquakes in Lorca, Spain.

Prim Care Companion CNS Disord 2015 26;17(1). Epub 2015 Feb 26.

Mental Health Branch of Murcia Health Service, El Palmar (Mssrs Martin and Garriga) and La Viña Health Centre, Lorca (Ms Egea), Murcia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4088/PCC.14m01691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468883PMC
July 2015

Exercise intensity progression for exercises performed on unstable and stable platforms based on ankle muscle activation.

Gait Posture 2014 18;39(1):404-9. Epub 2013 Aug 18.

Laboratory of Physical Activity and Health, Research Group in Sport and Health, Department of Physical Education and Sports, University of Valencia, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gaitpost.2013.08.006DOI Listing
July 2014

Mining the potential of label-free biosensors for seven-transmembrane receptor drug discovery.

Prog Mol Biol Transl Sci 2013 ;115:123-42

GlaxoSmithKline, Medicines Research Centre, Stevenage, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-394587-7.00003-8DOI Listing
June 2014

[Skin necrosis in a patient with temporal arteritis].

Reumatol Clin 2011 May-Jun;7(3):198-9. Epub 2011 Feb 22.

Servicio de Reumatología, Hospital 12 de Octubre, Madrid, España.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reuma.2010.06.003DOI Listing
April 2012

Self-correction in tripronucleated human embryos.

Fertil Steril 2011 Oct;96(4):951-6

Universitary Institute Instituto Valenciano de Infertilidad Valencia, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fertnstert.2011.07.1087DOI Listing
October 2011

Label-free imaging and temporal signature in phenotypic cellular assays: a new approach to high-content screening.

Authors:
Julio Martin

Curr Protoc Pharmacol 2010 Sep;Chapter 9:Unit 9.13

GlaxoSmithKline, Tres Cantos, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471141755.ph0913s50DOI Listing
September 2010

Pore size dependent dynamics of confined water probed by FIR spectroscopy.

Phys Chem Chem Phys 2010 Jul 11;12(26):6928-32. Epub 2010 May 11.

Instituto de Investigaciones Químicas, Avda. Américo Vespucio, 49, 41092 Seville, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c000985gDOI Listing
July 2010

Temperature-induced water release and uptake in organic porous networks.

J Phys Chem B 2010 May;114(17):5694-9

Instituto de Investigaciones Químicas, Avda. Américo Vespucio, 49, 41092 Seville, Spain.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/jp911930k
Publisher Site
http://dx.doi.org/10.1021/jp911930kDOI Listing
May 2010

Statistics and decision making in high-throughput screening.

Methods Mol Biol 2009 ;565:69-106

Molecular Discovery Research, Glaxo SmithKline, Tres Cantos, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60327-258-2_4DOI Listing
September 2009

Conference Report: update on screening methodologies.

Future Med Chem 2009 May;1(2):253-6

GlaxoSmithKline, Centro de Investigación Básica S.L., Santiago de Grisolia, 4, 28760 Tres Cantos, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/fmc.09.30DOI Listing
May 2009

Heteroparental blastocyst production from microsurgically corrected tripronucleated human embryos.

Fertil Steril 2006 Dec 24;86(6):1601-7. Epub 2006 Oct 24.

IVI Foundation, IVI University, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fertnstert.2006.04.047DOI Listing
December 2006

Distinct dynamic behaviors of water molecules in hydrated pores.

J Am Chem Soc 2006 Aug;128(31):10008-9

Instituto de Bioorganica, Universidad de La Laguna, CSIC, Ctra. Vieja de La Esperanza 2, 38206 La Laguna, Tenerife, Spain.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/ja063223j
Publisher Site
http://dx.doi.org/10.1021/ja063223jDOI Listing
August 2006

Molecular diversity of voltage-gated sodium channel alpha and beta subunit mRNAs in human tissues.

Eur J Pharmacol 2006 Jul 3;541(1-2):9-16. Epub 2006 May 3.

Instituto de Investigaciones Químicas, Centro de Investigaciones Científicas Isla de la Cartuja, 41092 Sevilla, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejphar.2006.04.025DOI Listing
July 2006

Global gene expression profiling of human endometrial receptivity.

J Reprod Immunol 2004 Aug;63(1):41-9

Instituto Valenciano de Infertilidad (IVI), Plaza de la Policía Local, 3, 46015 Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jri.2004.02.003DOI Listing
August 2004

The leptin system during human endometrial receptivity and preimplantation development.

J Clin Endocrinol Metab 2004 May;89(5):2442-51

Department of Pediatrics, School of Medicine, University of Valencia, 46010 Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2003-032127DOI Listing
May 2004

Cause of hydration/dehydration in condensed organic materials: synthesis of hydrophobic pores.

Org Lett 2004 Mar;6(6):877-80

Instituto de Bioorgánica, Universidad de La Laguna, CSIC, Ctra. Vieja de la Esperanza, 2, 38206 La Laguna, Tenerife, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol036335dDOI Listing
March 2004

A combined approach for gene discovery identifies insulin-like growth factor-binding protein-related protein 1 as a new gene implicated in human endometrial receptivity.

J Clin Endocrinol Metab 2003 Apr;88(4):1849-57

Instituto Valenciano de Infertilidad (IVI-FIVIER), Department of Pediatrics, Obstetrics, and Gynecology, School of Medicine, University of Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2002-020724DOI Listing
April 2003

Controlled incorporation of water molecules into carboxy hydrogen-bond networks: a designed approach.

Org Lett 2003 Mar;5(5):641-4

Instituto de Bioorgánica, Universidad de La Laguna, CSIC, Crta. Vieja de La Esperanza, 2, 38206 La Laguna, Tenerife, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol027332oDOI Listing
March 2003

Human endometrial receptivity: gene regulation.

J Reprod Immunol 2002 May-Jun;55(1-2):131-9

Instituto Valenciano de Infertilidad (IVI), Valencia University, C/ Guardia Civil 23, 46020 Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0165-0378(01)00140-1DOI Listing
October 2002

Methamphetamine-induced dopaminergic neurotoxicity in mice: long-lasting sensitization to the locomotor stimulation and desensitization to the rewarding effects of methamphetamine.

Prog Neuropsychopharmacol Biol Psychiatry 2002 Oct;26(6):1177-83

Department of Psychiatry and Behavioral Sciences (R-629), Gautier Building Room No. 503, 1011 NW 15th Street, University of Miami School of Medicine, Miami, FL 33136, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0278-5846(02)00257-9DOI Listing
October 2002

Magnetic resonance of focal liver lesions in hepatic cirrhosis and chronic hepatitis.

Semin Ultrasound CT MR 2002 Feb;23(1):62-78

Unitat de Diagnòstic d'Alta Tecnologia-Centre Diagnòstic, Corporació Sanitària del Parc Taulí, Sabadell, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0887-2171(02)90029-6DOI Listing
February 2002

Cocaine-induced conditioned place preference in mice: induction, extinction and reinstatement by related psychostimulants.

Neuropsychopharmacology 2002 Jan;26(1):130-4

Department of Psychiatry and Behavioral Sciences, R-629, Gautier Building Room # 503, 1011 NW 15th Street, University of Miami School of Medicine, Miami, FL 33136, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1016/S0893-133X(01)00303-
Publisher Site
http://dx.doi.org/10.1016/S0893-133X(01)00303-7DOI Listing
January 2002

Ring-Closing Metathesis in the Synthesis of Large and Medium-Sized Oxacycles. Application to the Synthesis of Polyoxygenated Macrocycles.

J Org Chem 1999 Jun;64(13):4798-4816

Centro de Investigaciones Científicas Isla de La Cartuja, Instituto de Investigaciones Químicas, CSIC, Sevilla, C) Américo Vespucio, s/n 41092 Seville, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo9901438DOI Listing
June 1999

Simple Designs for the Construction of Complex Trans-Fused Polyether Toxin Frameworks. A Convergent Strategy Based on Hydroxy Ketone Cyclization of C-Linked Oxacycles.

J Org Chem 1996 May;61(9):3003-3016

Centro de Productos Naturales Orgánicos Antonio González, Universidad de La Laguna-CSIC, Carretera de la Esperanza, 2, 38206 La Laguna, Tenerife, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo950547+DOI Listing
May 1996