Julio Castaño

Julio Castaño

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Julio Castaño

Julio Castaño

Publications by authors named "Julio Castaño"

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Generation of two transgene-free human iPSC lines from CD133 cord blood cells.

Stem Cell Res 2019 04 28;36:101410. Epub 2019 Feb 28.

Inbiomed Foundation, San Sebastian, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101410DOI Listing
April 2019

Generation, genome edition and characterization of iPSC lines from a patient with coenzyme Q deficiency harboring a heterozygous mutation in COQ4 gene.

Stem Cell Res 2017 10 16;24:144-147. Epub 2016 Sep 16.

Josep Carreras Leukemia Research Institute, Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain; Instituciò Catalana de Recerca I Estudis Avançats (ICREA), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.09.007DOI Listing
October 2017

Autogenous Control of 5′TOP mRNA Stability by 40S Ribosomes.

Mol Cell 2017 07 29;67(1):55-70.e4. Epub 2017 Jun 29.

Metabolism and Cancer Group, Molecular Mechanisms And Experimental Therapy In Oncology Program, Bellvitge Biomedical Research Institute, IDIBELL, 08908 Barcelona, Spain; Division of Hematology/Oncology, Department of Internal Medicine, University of Cincinnati Medical School, Cincinnati, OH 45267-0508, USA; Physiological Sciences Department, Faculty of Medicine and Health Science, University of Barcelona, 08908 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553558PMC
July 2017

Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes.

Stem Cell Reports 2017 06 18;8(6):1573-1586. Epub 2017 May 18.

Josep Carreras Leukemia Research Institute, Department of Biomedicine, School of Medicine, Universitat de Barcelona, Casanova 143, Barcelona 08036, Spain; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), ISCIII, Madrid 28031, Spain; Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona 08010, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470078PMC
June 2017

Efficient Recreation of t(11;22) EWSR1-FLI1 in Human Stem Cells Using CRISPR/Cas9.

Stem Cell Reports 2017 05;8(5):1408-1420

Molecular Cytogenetics Group, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid 28029, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711173016
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http://dx.doi.org/10.1016/j.stemcr.2017.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425785PMC
May 2017

Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the "safe harbor" AAVS1 locus.

Stem Cell Res 2017 05 22;21:137-140. Epub 2017 Apr 22.

Josep Carreras Leukemia Research Institute, Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain; Center for Networked Biomedical Research on Cancer (CIBERONC), ISCIII, Madrid, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.scr.2017.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446316PMC
May 2017

Proinflammatory signals are insufficient to drive definitive hematopoietic specification of human HSCs in vitro.

Exp Hematol 2017 Jan 28;45:85-93.e2. Epub 2016 Sep 28.

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.09.007DOI Listing
January 2017

Fast and Efficient Neural Conversion of Human Hematopoietic Cells.

Curr Protoc Stem Cell Biol 2016 Nov;39(1):1F.15.1-1F.15.20

Center for Regenerative Medicine in Barcelona, (CMRB), Barcelona, Spain.

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http://dx.doi.org/10.1002/cpsc.16DOI Listing
November 2016

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair.

Oncotarget 2016 May;7(21):30440-52

Josep Carreras Leukemia Research Institute, Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.8938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058691PMC
May 2016

Activated KRAS Cooperates with MLL-AF4 to Promote Extramedullary Engraftment and Migration of Cord Blood CD34+ HSPC But Is Insufficient to Initiate Leukemia.

Cancer Res 2016 04 2;76(8):2478-89. Epub 2016 Feb 2.

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain. Instituciò Catalana Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2769DOI Listing
April 2016

Concise review: Generation of neurons from somatic cells of healthy individuals and neurological patients through induced pluripotency or direct conversion.

Stem Cells 2014 Nov;32(11):2811-7

Instituto de Fisiología Celular-Neurociencias, Universidad Nacional Autónoma de México, México, D.F, México; Centro GENYO, Granada, Spain.

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http://dx.doi.org/10.1002/stem.1782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282532PMC
November 2014

Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target.

J Biol Chem 2012 Dec 24;287(52):43472-81. Epub 2012 Oct 24.

Drug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona 08035 Spain.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.428466
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http://dx.doi.org/10.1074/jbc.M112.428466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527934PMC
December 2012

LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells.

Nat Cell Biol 2011 Jun 22;13(6):652-9. Epub 2011 May 22.

Center of Regenerative Medicine in Barcelona, Dr. Aiguader, 88, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1038/ncb2246DOI Listing
June 2011

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

Cancer Res 2009 Sep 8;69(18):7430-8. Epub 2009 Sep 8.

Group of Molecular Oncology, Biochemistry Research Center (CIBBIM-Nanomedicine) and Department of Pathology, Vall d'Hebron Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0706DOI Listing
September 2009

EPH receptors in cancer.

Histol Histopathol 2008 08;23(8):1011-23

Drug Delivery and Targeting Group, Nanomedicine Program, Molecular Biology and Biochemistry Research Center (CIBBIM), Vall d'Hebron Hospital Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.14670/HH-23.1011DOI Listing
August 2008

Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA.

Mol Cell Biol 2007 Mar 28;27(5):1745-57. Epub 2006 Dec 28.

Unitat de Biofísica, Departament Bioquímica i Biologia Molecular, Facultat de Medicina, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain.

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http://dx.doi.org/10.1128/MCB.01974-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820477PMC
March 2007

Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. Implications for the regulation of beta-catenin/Tcf-4-dependent transcription.

J Biol Chem 2006 Jan 23;281(3):1401-11. Epub 2005 Nov 23.

Unitat de Biofísica, Departament de Bioquímica i Biologia Molecular, Facultat de Medicina, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain.

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http://dx.doi.org/10.1074/jbc.M508153200DOI Listing
January 2006

beta-Catenin and plakoglobin N- and C-tails determine ligand specificity.

J Biol Chem 2004 Nov 20;279(48):49849-56. Epub 2004 Sep 20.

Unitat de Biofísica, Departament de Bioquímica i Biologia Molecular, Facultat de Medicina, Universitat Autònoma de Barcelona, E-08193 Bellaterra.

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http://dx.doi.org/10.1074/jbc.M408685200DOI Listing
November 2004

Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription.

Mol Cell Biol 2003 Oct;23(20):7391-402

Unitat de Biofísica, Departament de Bioquímica i Biologia Molecular, Facultat de Medicina, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC230329PMC
http://dx.doi.org/10.1128/mcb.23.20.7391-7402.2003DOI Listing
October 2003

p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction.

Mol Cell Biol 2003 Apr;23(7):2287-97

Unitat de Biofísica, Departament de Bioquímica i Biologia Molecular, Facultat de Medicina, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150740PMC
http://dx.doi.org/10.1128/mcb.23.7.2287-2297.2003DOI Listing
April 2003

Beta-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to beta-catenin.

J Biol Chem 2002 Aug 20;277(35):31541-50. Epub 2002 Jun 20.

Unitat de Biofisica, Departament de Bioquimica i Biologia Molecular, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

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http://dx.doi.org/10.1074/jbc.M204376200DOI Listing
August 2002