Julio Benítez

Julio Benítez

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Julio Benítez

Julio Benítez

Publications by authors named "Julio Benítez"

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Modeling Motor Neuron Resilience in ALS Using Stem Cells.

Stem Cell Reports 2019 Jun 9;12(6):1329-1341. Epub 2019 May 9.

Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711193013
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http://dx.doi.org/10.1016/j.stemcr.2019.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565614PMC
June 2019

Engineering Human Epidermal Growth Receptor 2-Targeting Hepatitis B Virus Core Nanoparticles for siRNA Delivery and .

ACS Appl Nano Mater 2018 Jul 20;1(7):3269-3282. Epub 2018 Jun 20.

Institute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, U.K.

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http://pubs.acs.org/doi/10.1021/acsanm.8b00480
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http://dx.doi.org/10.1021/acsanm.8b00480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312360PMC
July 2018

LCM-Seq: A Method for Spatial Transcriptomic Profiling Using Laser Capture Microdissection Coupled with PolyA-Based RNA Sequencing.

Methods Mol Biol 2018 ;1649:95-110

Department of Neuroscience, Karolinska Institutet, Retzius v. 8, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1007/978-1-4939-7213-5_6DOI Listing
June 2018

Revealing allele-specific gene expression by single-cell transcriptomics.

Int J Biochem Cell Biol 2017 09 31;90:155-160. Epub 2017 May 31.

Department of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.05.029DOI Listing
September 2017

Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons.

Stem Cell Reports 2017 09 24;9(3):742-751. Epub 2017 Aug 24.

Department of Experimental Medical Science and Lund Stem Cell Center BMC, Lund University, 22632 Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599255PMC
September 2017

Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands.

J Inorg Biochem 2017 01 9;166:162-172. Epub 2016 Nov 9.

Cátedra de Química Inorgánica, Facultad de Química, Universidad de la República, Gral. Flores 2124, 11800, Montevideo, Uruguay. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01620134163038
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http://dx.doi.org/10.1016/j.jinorgbio.2016.11.010DOI Listing
January 2017

Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS.

Sci Rep 2016 05 16;6:25960. Epub 2016 May 16.

Department of Neuroscience, Karolinska Institutet, Retzius v. 8, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1038/srep25960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867585PMC
May 2016

Exploring Oxidovanadium(IV) Complexes as YopH Inhibitors: Mechanism of Action and Modeling Studies.

ACS Med Chem Lett 2015 Oct 31;6(10):1035-40. Epub 2015 Aug 31.

Centro de Biologia Molecular Estrutural-CEBIME, Universidade Federal de Santa Catarina , Campus Trindade, 88040-900 Florianópolis, Santa Catarina, Brasil.

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http://dx.doi.org/10.1021/acsmedchemlett.5b00267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641580PMC
October 2015

CYP2C8*3 polymorphism and donor age are associated with allograft dysfunction in kidney transplant recipients treated with calcineurin inhibitors.

J Clin Pharmacol 2013 Apr 20;53(4):427-34. Epub 2013 Feb 20.

Division of Pharmacology, Department of Medical and Surgical Therapeutics, Medical School, University of Extremadura, Badajoz, Spain.

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http://dx.doi.org/10.1002/jcph.15DOI Listing
April 2013

ABCB1 polymorphisms are associated with cyclosporine-induced nephrotoxicity and gingival hyperplasia in renal transplant recipients.

Eur J Clin Pharmacol 2013 Mar 11;69(3):385-93. Epub 2012 Aug 11.

Department of Surgical and Medical Therapeutics, Division of Pharmacology, Medical School, University of Extremadura, Av. Elvas s/n 06071, Badajoz, Spain.

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http://link.springer.com/10.1007/s00228-012-1355-x
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http://dx.doi.org/10.1007/s00228-012-1355-xDOI Listing
March 2013

Haplotypes in the 5'-untranslated region of the CYP1A2 gene are inversely associated with lung cancer risk but do not correlate with caffeine metabolism.

Environ Mol Mutagen 2013 Mar 9;54(2):124-32. Epub 2012 Nov 9.

Department of Medical & Surgical Therapeutics, Division of Pharmacology, Medical School, University of Extremadura, Badajoz, Spain.

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http://dx.doi.org/10.1002/em.21747DOI Listing
March 2013

Comparative cytochrome p450 in vitro inhibition by atypical antipsychotic drugs.

ISRN Pharmacol 2013 13;2013:792456. Epub 2013 Feb 13.

Department of Medical and Surgical Therapeutics, Division of Pharmacology, Medical School, University of Extremadura, Av. Elvas s/n, 06071 Badajoz, Spain.

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http://dx.doi.org/10.1155/2013/792456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586484PMC
March 2013

Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation.

Transpl Int 2012 Apr 28;25(4):471-80. Epub 2012 Feb 28.

Department of Medical and Surgical Therapeutics, Medical School, University of Extremadura, Badajoz, Spain.

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http://dx.doi.org/10.1111/j.1432-2277.2012.01446.xDOI Listing
April 2012

GST polymorphisms interact with dietary factors to modulate lung cancer risk: study in a high-incidence area.

Nutr Cancer 2010 ;62(6):750-8

Department of Pharmacology, Medical School, University of Extremadura, Badajoz, Spain.

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http://dx.doi.org/10.1080/01635581003605946DOI Listing
November 2010

Pharmacogenetic testing and therapeutic drug monitoring are complementary tools for optimal individualization of drug therapy.

Eur J Clin Pharmacol 2010 Aug 27;66(8):755-74. Epub 2010 Jun 27.

Department of Medical and Surgical Therapeutics, Division of Clinical Pharmacology, Medical School, University of Extremadura, 06071 Badajoz, Spain.

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http://dx.doi.org/10.1007/s00228-010-0857-7DOI Listing
August 2010

A novel vanadyl complex with a polypyridyl DNA intercalator as ligand: a potential anti-protozoa and anti-tumor agent.

J Inorg Biochem 2009 Oct 24;103(10):1386-94. Epub 2009 Jul 24.

Cátedra de Química Inorgánica, Facultad de Química, Universidad de la República, Gral. Flores 2124, C. C. 1157, 11800 Montevideo, Uruguay.

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http://dx.doi.org/10.1016/j.jinorgbio.2009.07.013DOI Listing
October 2009

Design of vanadium mixed-ligand complexes as potential anti-protozoa agents.

J Inorg Biochem 2009 Apr 7;103(4):609-16. Epub 2008 Nov 7.

Cátedra de Química Inorgánica, Facultad de Química, Universidad de la República, Gral. Flores 2124, C. C. 1157, Montevideo, Uruguay.

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http://dx.doi.org/10.1016/j.jinorgbio.2008.10.018DOI Listing
April 2009

Effect of neurotransmitters on NADPH-cytochrome P450 reductase in vitro activity.

Drug Metab Lett 2007 Aug;1(3):172-5

Department of Pharmacology, Medical School, University of Extremadura, Badajoz, Spain.

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August 2007

Retinal toxic reactions following photopheresis.

Arch Dermatol 2007 May;143(5):622-5

Department of Hematology, University Hospital Infanta Cristina, Avda Elvas s/n, E-06080 Badajoz, Spain.

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http://dx.doi.org/10.1001/archderm.143.5.622DOI Listing
May 2007

The effect of CYP2J2, CYP3A4, CYP3A5 and the MDR1 polymorphisms and gender on the urinary excretion of the metabolites of the H-receptor antihistamine ebastine: a pilot study.

Br J Clin Pharmacol 2006 Aug;62(2):177-86

Department of Pharmacology and Psychiatry, Medical School and Clinical Pharmacology Unit, Infanta Cristina University Hospital, University of Extremadura, E-06071-Badajoz, Spain.

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http://dx.doi.org/10.1111/j.1365-2125.2006.02578.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885094PMC
August 2006

Differences in CYP3A5*3 genotype distribution and combinations with other polymorphisms between Spaniards and Other Caucasian populations.

Ther Drug Monit 2005 Dec;27(6):819-21

Department of Pharmacology and Psychiatry, Medical School, and Clinical Pharmacology Unit, Infanta Cristina University Hospital, University of Extremadura, Badajoz, Spain.

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http://dx.doi.org/10.1097/01.ftd.0000186914.32038.a0DOI Listing
December 2005

Evaluation of a drug-drug interaction alert structure through the retrospective analysis of statins-macrolides co-prescriptions.

Basic Clin Pharmacol Toxicol 2005 Apr;96(4):289-94

Drug Surveillance Center of Extremadura, Department of Pharmacology and Psychiatry & Clinical Pharmacology Unit, Infanta Cristina University Hospital, Medical School, University of Extremadura, Badajoz, Spain.

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http://dx.doi.org/10.1111/j.1742-7843.2005.pto960403.xDOI Listing
April 2005

Using a computerized drug prescription screening system to trace drug interactions in an outpatient setting.

Ann Pharmacother 2004 Jul-Aug;38(7-8):1301-6. Epub 2004 Jun 3.

Department of Pharmacology and Psychiatry, University of Extremadura Medical School, Badajoz, Spain.

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http://dx.doi.org/10.1345/aph.1D549DOI Listing
October 2004

Potential role of cerebral cytochrome P450 in clinical pharmacokinetics: modulation by endogenous compounds.

Clin Pharmacokinet 2004 ;43(11):693-706

Department of Pharmacology and Psychiatry, Medical School, University of Extremadura, Badajoz, Spain.

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http://dx.doi.org/10.2165/00003088-200443110-00001DOI Listing
September 2004

Early detection of drug interactions utilizing a computerized drug prescription handling system-focus on cerivastatin-gemfibrozil.

Eur J Clin Pharmacol 2004 Feb 21;59(12):917-21. Epub 2004 Jan 21.

Drug Surveillance Center of Extremadura, Department of Pharmacology, Medical School, University of Extremadura, Avenida de Elvas, 06071 Badajoz, Spain.

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http://dx.doi.org/10.1007/s00228-003-0711-2DOI Listing
February 2004

Applicability of an assay for routine monitoring of highly variable concentrations of olanzapine based on HPLC with mass spectrometric detection.

Clin Chem 2003 Dec;49(12):2088-91

Department of Pharmacology and Psychiatry, Extremadura University School of Medicine, E-06071 Badajoz, Spain.

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http://dx.doi.org/10.1373/clinchem.2003.022517DOI Listing
December 2003

Role of the smoking-induced cytochrome P450 (CYP)1A2 and polymorphic CYP2D6 in steady-state concentration of olanzapine.

J Clin Psychopharmacol 2003 Apr;23(2):119-27

Department of Pharmacology and Psychiatry, Extremadura University School of Medicine, Badajoz, Spain.

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http://dx.doi.org/10.1097/00004714-200304000-00003DOI Listing
April 2003

N-acetyltransferase 2 single-nucleotide polymorphisms and risk of gastric carcinoma.

Eur J Clin Pharmacol 2002 May 17;58(2):115-8. Epub 2002 Apr 17.

Gastroenterology Service, Hospital Clínico San Carlos, Medical School, Universidad Complutense, Madrid, Spain.

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http://dx.doi.org/10.1007/s00228-002-0460-7DOI Listing
May 2002