Publications by authors named "Juliet Taylor"

54Publications

STING-Mediated Autophagy Is Protective against HO-Induced Cell Death.

Int J Mol Sci 2020 Sep 25;21(19). Epub 2020 Sep 25.

Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, Melbourne 3010, Australia.

View Article and Find Full Text PDF
September 2020

Abrogation of type-I interferon signalling alters the microglial response to Aβ.

Sci Rep 2020 02 21;10(1):3153. Epub 2020 Feb 21.

Department of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, Australia.

View Article and Find Full Text PDF
February 2020

The use of bioactive matrices in regenerative therapies for traumatic brain injury.

Acta Biomater 2020 01 18;102:1-12. Epub 2019 Nov 18.

Department of Pharmacology and Therapeutics, The University of Melbourne, Level 8, Building 181, Grattan Street, Parkville, VIC 3010, Australia. Electronic address:

View Article and Find Full Text PDF
January 2020

Inflammation in Traumatic Brain Injury: Roles for Toxic A1 Astrocytes and Microglial-Astrocytic Crosstalk.

Neurochem Res 2019 Jun 19;44(6):1410-1424. Epub 2019 Jan 19.

The Florey Institute of Neuroscience and Mental Health, Parkville, VIC, 3051, Australia.

View Article and Find Full Text PDF
June 2019

STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury.

J Neuroinflammation 2018 Nov 21;15(1):323. Epub 2018 Nov 21.

Neuropharmacology Laboratory, Department of Pharmacology & Therapeutics, University of Melbourne, Parkville, Melbourne, 3010, Australia.

View Article and Find Full Text PDF
November 2018

The involvement of microglia in Alzheimer's disease: a new dog in the fight.

Br J Pharmacol 2019 09 18;176(18):3533-3543. Epub 2018 Dec 18.

Neuropharmacology Laboratory, Department of Pharmacology and Therapeutics, University of Melbourne, Melbourne, VIC, Australia.

View Article and Find Full Text PDF
September 2019

Generation and characterisation of a parkin-Pacrg knockout mouse line and a Pacrg knockout mouse line.

Sci Rep 2018 05 14;8(1):7528. Epub 2018 May 14.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Children's Research Institute, Flemington Road, Parkville, Victoria, Australia.

View Article and Find Full Text PDF
May 2018

Type-I interferon pathway in neuroinflammation and neurodegeneration: focus on Alzheimer's disease.

J Neural Transm (Vienna) 2018 05 4;125(5):797-807. Epub 2017 Jul 4.

Neuropharmacology Laboratory, Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, VIC, Australia.

View Article and Find Full Text PDF
May 2018

Type-I interferon signalling through IFNAR1 plays a deleterious role in the outcome after stroke.

Neurochem Int 2017 Sep 22;108:472-480. Epub 2017 Jun 22.

Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, Australia. Electronic address:

View Article and Find Full Text PDF
September 2017

Type-I interferons mediate the neuroinflammatory response and neurotoxicity induced by rotenone.

J Neurochem 2017 04;141(1):75-85

Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, Victoria, Australia.

View Article and Find Full Text PDF
April 2017

Type-1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease.

Glia 2016 09 12;64(9):1590-604. Epub 2016 Jul 12.

Neuropharmacology Laboratory, Department of Pharmacology & Therapeutics, University of Melbourne, Parkville, Melbourne, 3010, Australia.

View Article and Find Full Text PDF
September 2016

Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype.

Acta Neuropathol Commun 2016 07 11;4(1):72. Epub 2016 Jul 11.

Department of Pharmacology and Therapeutics, University of Melbourne, 8th floor, Medical building, Grattan St, Parkville, Melbourne, 3010, Victoria, Australia.

View Article and Find Full Text PDF
July 2016

Evidence for the recruitment of autophagic vesicles in human brain after stroke.

Neurochem Int 2016 06 27;96:62-8. Epub 2016 Feb 27.

Department of Pharmacology & Therapeutics, University of Melbourne, Parkville, Australia. Electronic address:

View Article and Find Full Text PDF
June 2016

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease.

J Neurochem 2016 Feb 18;136(3):457-74. Epub 2015 Nov 18.

Department of Pharmacology and Therapeutics, University of Melbourne, Melbourne, Victoria, Australia.

View Article and Find Full Text PDF
February 2016

Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro.

J Neuroinflammation 2015 Apr 12;12:71. Epub 2015 Apr 12.

Department of Pharmacology and Therapeutics, University of Melbourne, 8th floor, Medical building, Grattan St, Parkville, Melbourne, 3010, VIC, Australia.

View Article and Find Full Text PDF
April 2015

The contribution of astrocytes and microglia to traumatic brain injury.

Br J Pharmacol 2016 Feb 24;173(4):692-702. Epub 2015 Apr 24.

Neuropharmacology Laboratory, Department of Pharmacology, University of Melbourne, Melbourne, Vic., Australia.

View Article and Find Full Text PDF
February 2016

Disrupted auto-regulation of the spliceosomal gene SNRPB causes cerebro-costo-mandibular syndrome.

Nat Commun 2014 Jul 22;5:4483. Epub 2014 Jul 22.

1] Department of Medical Genetics, University of Calgary, Calgary, Alberta, Canada T2N 4N1 [2] Alberta Children's Hospital Research Institute for Child and Maternal Health, Calgary, Alberta, Canada T3B 6A8 [3] Department of Computer Science, University of Toronto, Ontario, Canada. [4].

View Article and Find Full Text PDF
July 2014

A turner syndrome patient carrying a mosaic distal x chromosome marker.

Case Rep Genet 2014 17;2014:597314. Epub 2014 Mar 17.

Diagnostic Genetics, LabPlus, Auckland City Hospital, P.O. Box 110031, Auckland 1148, New Zealand.

View Article and Find Full Text PDF
April 2014

A case of 17q21.31 microduplication and 7q31.33 microdeletion, associated with developmental delay, microcephaly, and mild dysmorphic features.

Case Rep Genet 2014 4;2014:658570. Epub 2014 Feb 4.

Diagnostic Genetics, LabPlus, Auckland City Hospital, P.O. Box 110031, Auckland 1148, New Zealand.

View Article and Find Full Text PDF
March 2014

Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells.

J Neuroinflammation 2014 Mar 6;11:43. Epub 2014 Mar 6.

Department of Pharmacology, University of Melbourne, 8th floor, Medical building, Grattan St, Parkville 3010, VIC, Australia.

View Article and Find Full Text PDF
March 2014

Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease.

Neurobiol Aging 2014 May 29;35(5):1012-23. Epub 2013 Oct 29.

Department of Pharmacology, University of Melbourne, Melbourne, Victoria, Australia. Electronic address:

View Article and Find Full Text PDF
May 2014

Delineation of 2q32q35 deletion phenotypes: two apparent "proximal" and "distal" syndromes.

Case Rep Genet 2013 9;2013:823451. Epub 2013 Jun 9.

Diagnostic Genetics, LabPlus, Auckland City Hospital, P.O. Box 110031, Auckland 1148, New Zealand.

View Article and Find Full Text PDF
July 2013

Neuroinflammation and oxidative stress: co-conspirators in the pathology of Parkinson's disease.

Neurochem Int 2013 Apr 4;62(5):803-19. Epub 2013 Jan 4.

Neuropharmacology Laboratory, Department of Pharmacology, University of Melbourne, Victoria, Australia.

View Article and Find Full Text PDF
April 2013

Parkin co-regulated gene is involved in aggresome formation and autophagy in response to proteasomal impairment.

Exp Cell Res 2012 Oct 28;318(16):2059-70. Epub 2012 May 28.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Victoria, Australia.

View Article and Find Full Text PDF
October 2012

A newborn with likely Okamoto syndrome.

Clin Dysmorphol 2010 Apr;19(2):103-6

Auckland City Hospital, New Zealand.

View Article and Find Full Text PDF
April 2010

Expression and localization of the Parkin co-regulated gene in mouse CNS suggests a role in ependymal cilia function.

Neurosci Lett 2009 Aug 20;460(1):97-101. Epub 2009 May 20.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.

View Article and Find Full Text PDF
August 2009

Molecular analysis of the PArkin co-regulated gene and association with male infertility.

Fertil Steril 2010 May 6;93(7):2262-8. Epub 2009 Mar 6.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Children's Research Institute, Melbourne, 3052, Victoria, Australia.

View Article and Find Full Text PDF
May 2010

Analysis of PArkin Co-Regulated Gene in a Taiwanese-ethnic Chinese cohort with early-onset Parkinson's disease.

Parkinsonism Relat Disord 2009 Jul 3;15(6):417-21. Epub 2009 Feb 3.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Victoria, Australia.

View Article and Find Full Text PDF
July 2009

Identification and validation of control cell lines for accurate parkin dosage analysis.

J Neurosci Methods 2009 Jan 5;176(2):68-71. Epub 2008 Sep 5.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.

View Article and Find Full Text PDF
January 2009

Lack of evidence for association of a parkin promoter polymorphism with early-onset Parkinson's disease in a Chinese population.

Parkinsonism Relat Disord 2009 Feb 2;15(2):149-52. Epub 2008 Apr 2.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Melbourne, Australia.

View Article and Find Full Text PDF
February 2009

Regional and cellular localisation of Parkin co-regulated gene in developing and adult mouse brain.

Brain Res 2008 Mar 30;1201:177-86. Epub 2008 Jan 30.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Melbourne, Victoria, 3052, Australia.

View Article and Find Full Text PDF
March 2008

Parkin Co-Regulated Gene (PACRG) is regulated by the ubiquitin-proteasomal system and is present in the pathological features of Parkinsonian diseases.

Neurobiol Dis 2007 Aug 18;27(2):238-47. Epub 2007 May 18.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Children's Research Institute, Melbourne, Victoria 3052, Australia.

View Article and Find Full Text PDF
August 2007

Potential contribution of NF-kappaB in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemia-reperfusion injury.

Stroke 2006 Jun 20;37(6):1533-8. Epub 2006 Apr 20.

Centre for Functional Genomics and Human Disease, Monash Institute of Medical Research, Monash University, Melbourne, Australia.

View Article and Find Full Text PDF
June 2006

Reactive oxygen species and the modulation of stroke.

Free Radic Biol Med 2005 Jun;38(11):1433-44

Centre for Functional Genomics & Human Disease, Monash Institute of Reproduction and Development, Monash University, Melbourne, VIC 3168, Australia.

View Article and Find Full Text PDF
June 2005

Monolysocardiolipins accumulate in Barth syndrome but do not lead to enhanced apoptosis.

J Lipid Res 2005 Jun 1;46(6):1182-95. Epub 2005 Apr 1.

Laboratory of Genetic Metabolic Diseases, Department of Clinical Chemistry, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands.

View Article and Find Full Text PDF
June 2005

Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death.

J Neurochem 2005 Jan;92(2):283-93

Centre for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Monash University, Melbourne, Australia.

View Article and Find Full Text PDF
January 2005

Akt phosphorylation and NFkappaB activation are counterregulated under conditions of oxidative stress.

Exp Cell Res 2004 Nov;300(2):463-75

Centre for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Monash University, Melbourne, Victoria, Australia.

View Article and Find Full Text PDF
November 2004

Impact of oxidative stress on neuronal survival.

Clin Exp Pharmacol Physiol 2004 Jul;31(7):397-406

Centre for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Monash University, Melbourne, Victoria, Australia.

View Article and Find Full Text PDF
July 2004

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death.

Free Radic Biol Med 2004 Jan;36(1):53-64

Centre for Functional Genomics and Human Disease, Monash University, Monash Medical Centre, Clayton, Victoria, Australia.

View Article and Find Full Text PDF
January 2004

Glutathione peroxidase-1 contributes to the neuroprotection seen in the superoxide dismutase-1 transgenic mouse in response to ischemia/reperfusion injury.

J Cereb Blood Flow Metab 2003 Jan;23(1):19-22

Center for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Monash University, Melbourne, Australia.

View Article and Find Full Text PDF
January 2003