Julien Sage

Julien Sage

UNVERIFIED PROFILE

Are you Julien Sage?   Register this Author

Register author
Julien Sage

Julien Sage

Publications by authors named "Julien Sage"

Are you Julien Sage?   Register this Author

100Publications

2488Reads

18Profile Views

Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix.

Mol Cell 2019 May 11;74(4):758-770.e4. Epub 2019 Apr 11.

Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2019.03.020DOI Listing
May 2019

Taking SCLC on a Bad LSD(1) Trip One NOTCH Further.

Authors:
Jun Kim Julien Sage

Trends Mol Med 2019 Apr 6;25(4):261-264. Epub 2019 Mar 6.

Department of Pediatrics, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmed.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511648PMC
April 2019

Road map for fibrolamellar carcinoma: progress and goals of a diversified approach.

J Hepatocell Carcinoma 2019 31;6:41-48. Epub 2019 Jan 31.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/JHC.S194764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362920PMC
January 2019

Beyond the Cell Cycle: Enhancing the Immune Surveillance of Tumors Via CDK4/6 Inhibition.

Mol Cancer Res 2018 10 22;16(10):1454-1457. Epub 2018 Jun 22.

Department of Pediatrics, Stanford University School of Medicine, Stanford, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-18-0201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170710PMC
October 2018

Cancer origins-genetics rules the day.

Science 2018 10;362(6410):30-31

Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aav1044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404521PMC
October 2018

Non-canonical functions of the RB protein in cancer.

Nat Rev Cancer 2018 07;18(7):442-451

Massachusetts General Hospital Cancer Center, Laboratory of Molecular Oncology, Harvard Medical School, Charlestown, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41568-018-0008-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693677PMC
July 2018

Tumor heterogeneity in small cell lung cancer defined and investigated in pre-clinical mouse models.

Transl Lung Cancer Res 2018 Feb;7(1):21-31

Department of Pediatrics, Stanford University, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://tlcr.amegroups.com/article/view/18906/15081
Publisher Site
http://dx.doi.org/10.21037/tlcr.2018.01.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835592PMC
February 2018

[Dual tumor suppressive and oncogenic roles for Notch signaling in small cell lung cancer].

Med Sci (Paris) 2018 Jan 31;34(1):24-26. Epub 2018 Jan 31.

Departments of pediatrics and genetics, Stanford university, 265 campus drive, Stanford, CA 94305, États-Unis.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/20183401007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476324PMC
January 2018

CD47 is not Over-Expressed in Fibrolamellar Hepatocellular Carcinoma.

Ann Clin Lab Sci 2017 Aug;47(4):395-402

Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA

View Article

Download full-text PDF

Source
August 2017

G1 cyclins protect pluripotency.

Nat Cell Biol 2017 03;19(3):149-150

Stanford University Medical Center, Departments of Pediatrics and Genetics, Stanford Medical School, SIM1 Building, 265 Campus Drive, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/ncb3480
Publisher Site
http://dx.doi.org/10.1038/ncb3480DOI Listing
March 2017

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

Cancer Cell 2017 02;31(2):286-299

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313262PMC
February 2017

An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes.

J Gene Med 2017 Jan;19(1-2)

Department of Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jgm.2940
Publisher Site
http://dx.doi.org/10.1002/jgm.2940DOI Listing
January 2017

Relationship between anti-depressant use and lung cancer survival.

Cancer Treat Res Commun 2017 29;10:33-39. Epub 2017 Jan 29.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ctarc.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603309PMC
January 2017

Novel functions for the transcription factor E2F4 in development and disease.

Cell Cycle 2016 Dec 18;15(23):3183-3190. Epub 2016 Oct 18.

a Departments of Pediatrics and Genetics , Stanford University , Stanford , CA , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15384101.2016.1234551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176148PMC
December 2016

Essential role for the planarian intestinal GATA transcription factor in stem cells and regeneration.

Dev Biol 2016 10 16;418(1):179-188. Epub 2016 Aug 16.

Department of Pediatrics, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055475PMC
http://dx.doi.org/10.1016/j.ydbio.2016.08.015DOI Listing
October 2016

Is the Canonical RAF/MEK/ERK Signaling Pathway a Therapeutic Target in SCLC?

J Thorac Oncol 2016 08 29;11(8):1233-1241. Epub 2016 Apr 29.

Department of Pediatrics, Stanford University, Stanford, California; Department of Genetics, Stanford University, Stanford, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2016.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391975PMC
August 2016

Loss of Pten Disrupts the Thymic Epithelium and Alters Thymic Function.

PLoS One 2016 25;11(2):e0149430. Epub 2016 Feb 25.

Department of Pediatrics, Stanford University, Stanford, CA, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149430PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767252PMC
July 2016

Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.

Cell Rep 2016 07 30;16(3):644-56. Epub 2016 Jun 30.

Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956576PMC
July 2016

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.

Cell 2016 Jul 30;166(2):328-342. Epub 2016 Jun 30.

Cancer Biology Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2016.05.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004630PMC
July 2016

Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase.

Transl Cancer Res 2016 Jun;5(3):330-333

Institute for Advanced Biosciences, INSERM U1209, CNRS UMR5309, Université Grenoble Alpes, 38700 Grenoble Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/tcr.2016.06.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358167PMC
June 2016

Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.

Genes Dev 2016 Apr 17;30(7):772-85. Epub 2016 Mar 17.

Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.275529.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826394PMC
April 2016

Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors.

Proc Natl Acad Sci U S A 2016 Apr 31;113(16):4464-9. Epub 2016 Mar 31.

Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305

View Article

Download full-text PDF

Source
https://www.nanets.net/nanets_cd/2015/pdfs/B4.pdf
Web Search
http://www.pnas.org/lookup/doi/10.1073/pnas.1600007113
Publisher Site
http://dx.doi.org/10.1073/pnas.1600007113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843455PMC
April 2016

Control of Proliferation and Cancer Growth by the Hippo Signaling Pathway.

Mol Cancer Res 2016 Feb 2;14(2):127-40. Epub 2015 Oct 2.

Department of Pediatrics, Stanford University School of Medicine, Stanford, California. Department of Genetics, Stanford University School of Medicine, Stanford, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-15-0305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755889PMC
February 2016

Crosstalk between stem cell and cell cycle machineries.

Curr Opin Cell Biol 2015 Dec 11;37:68-74. Epub 2015 Nov 11.

Department of Pathology, Stanford University, Stanford, CA 94305, USA; Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ceb.2015.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852861PMC
December 2015

Pancreatic cancer takes its Toll.

J Exp Med 2015 Nov;212(12):1988

Stanford University

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.21212insight1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647270PMC
November 2015

Comprehensive genomic profiles of small cell lung cancer.

Nature 2015 Aug 13;524(7563):47-53. Epub 2015 Jul 13.

1] Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany. [2] Department of Pathology, University Hospital Cologne, 50937 Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861069PMC
August 2015

The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung.

J Thorac Oncol 2015 Apr;10(4):553-64

*Hamon Center for Therapeutic Oncology Research and Department of Pathology, UT Southwestern Medical Center, Dallas, TX; †Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX; ‡Cancer Genomics Centre, The Netherlands Cancer Institute, Amsterdam, The Netherlands; §Departments of Pediatrics and Genetics, Stanford University, Stanford, CA; ‖Center for Cancer Research, National Cancer Institute, Bethesda, MD; ¶Division of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA; #David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142; **Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY; and ††Departementd'Anatomie et Cytologie Pathologiques, INSERM Unit 823, Centre Hospitalier Universitaire Albert Michallon, and Institut Albert Bonniot University, Grenoble, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0000000000000459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523224PMC
April 2015

Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis.

Cell Stem Cell 2015 Jan 13;16(1):39-50. Epub 2014 Nov 13.

Department of Pathology, Stanford University, Stanford, CA 94305, USA; Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2014.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389904PMC
January 2015

Cancer: The origin of human retinoblastoma.

Nature 2014 Oct 24;514(7522):312-3. Epub 2014 Sep 24.

Departments of Pediatrics and Genetics, Stanford University, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438154PMC
October 2014

Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo.

Cell Rep 2014 Jul 10;8(2):371-81. Epub 2014 Jul 10.

Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128252PMC
July 2014

From fly wings to targeted cancer therapies: a centennial for notch signaling.

Cancer Cell 2014 Mar;25(3):318-34

Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, NY 10016, USA; NYU Cancer Institute and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY 10016, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2014.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040351PMC
March 2014

A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.

Cancer Discov 2013 Dec 26;3(12):1364-77. Epub 2013 Sep 26.

Departments of 1Pediatrics, 2Genetics, and 5Medicine-Oncology, 3Vincent Coates Mass Spectrometry Laboratory, Stanford University, Stanford; and 4Division of Hematology/Oncology, Department of Internal Medicine, University of California Davis Cancer Center, University of California Davis School of Medicine, Sacramento, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-13-0183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864571PMC
December 2013

Defining a new vision for the retinoblastoma gene: report from the 3rd International Rb Meeting.

Cell Div 2013 Nov 21;8(1):13. Epub 2013 Nov 21.

Departments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1747-1028-8-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866465PMC
November 2013

The RB family is required for the self-renewal and survival of human embryonic stem cells.

Nat Commun 2012 ;3:1244

Department of Pediatrics, Stanford Medical School, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms2254DOI Listing
June 2013

IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.

Nat Med 2013 May 21;19(5):626-630. Epub 2013 Apr 21.

Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190012PMC
May 2013

RB goes mitochondrial.

Genes Dev 2013 May;27(9):975-9

Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.219451.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656326PMC
May 2013

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.

Nat Genet 2012 Oct 2;44(10):1104-10. Epub 2012 Sep 2.

Department of Translational Genomics, University of Cologne, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915822PMC
October 2012

Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer.

Cancer Res 2012 Oct 31;72(20):5418-27. Epub 2012 Aug 31.

McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-2083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473120PMC
October 2012

The retinoblastoma tumor suppressor and stem cell biology.

Authors:
Julien Sage

Genes Dev 2012 Jul;26(13):1409-20

Department of Pediatrics, Department of Genetics, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cancer Institute, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.193730.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403009PMC
July 2012

Genomics: The path to retinoblastoma.

Nature 2012 Jan 18;481(7381):269-70. Epub 2012 Jan 18.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/481269aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438155PMC
January 2012

PDGF signalling controls age-dependent proliferation in pancreatic β-cells.

Nature 2011 Oct 12;478(7369):349-55. Epub 2011 Oct 12.

Department of Developmental Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature10502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503246PMC
October 2011

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.

J Exp Med 2011 Sep 29;208(10):1963-76. Epub 2011 Aug 29.

Department of Genetics, Department of Pediatrics, Stanford University, Stanford, CA, USA; Department of Medical Chemistry, University of Liège, B-4000 Liège, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20110198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182062PMC
September 2011

Newly identified aspects of tumor suppression by RB.

Dis Model Mech 2011 Sep;4(5):581-5

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dmm.008060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180221PMC
September 2011

A dual role for A-type lamins in DNA double-strand break repair.

Cell Cycle 2011 Aug 1;10(15):2549-60. Epub 2011 Aug 1.

Radiation and Cancer Biology Division, Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180193PMC
http://dx.doi.org/10.4161/cc.10.15.16531DOI Listing
August 2011

Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Sci Transl Med 2011 Aug;3(96):96ra77

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, 251 Campus Drive, Stanford, CA 94305-5415, USA.

View Article

Download full-text PDF

Source
http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30013
Publisher Site
http://dx.doi.org/10.1126/scitranslmed.3001318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502016PMC
August 2011

miR than meets the eye.

Genes Dev 2011 Aug;25(16):1663-7

Department of Pediatrics, Stanford University, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://genesdev.cshlp.org/cgi/doi/10.1101/gad.17454011
Publisher Site
http://dx.doi.org/10.1101/gad.17454011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165930PMC
August 2011

Structure and function of the thymic microenvironment.

Front Biosci (Landmark Ed) 2011 Jun 1;16:2461-77. Epub 2011 Jun 1.

Department of Genetics, Coverdell Center, 500 DW Brooks Drive, University of Georgia, Athens, GA 30602, USA.

View Article

Download full-text PDF

Source
June 2011

Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.

PLoS One 2011 May 6;6(5):e19758. Epub 2011 May 6.

Department of Pediatrics, Stanford University, Stanford, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019758PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089631PMC
May 2011

RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo.

Mol Biol Cell 2011 Apr 2;22(7):931-9. Epub 2011 Feb 2.

Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.E10-11-0895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069018PMC
April 2011

Methylation of the retinoblastoma tumor suppressor by SMYD2.

J Biol Chem 2010 Nov 24;285(48):37733-40. Epub 2010 Sep 24.

Departments of Pediatrics, Stanford University, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M110.137612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988378PMC
November 2010

Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle.

Cell Stem Cell 2010 Aug;7(2):198-213

Baxter Laboratory for Stem Cell Biology, Department of Microbiology & Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19345909100028
Publisher Site
http://dx.doi.org/10.1016/j.stem.2010.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919350PMC
August 2010

RB's original CIN?

Genes Dev 2010 Jul 15;24(13):1329-33. Epub 2010 Jun 15.

Department of Pediatrics, Stanford University, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1948010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895191PMC
July 2010

Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions.

PLoS Genet 2010 Jun 24;6(6):e1001003. Epub 2010 Jun 24.

Departments of Pediatrics and Genetics, Stanford Medical School, Stanford, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1001003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891812PMC
June 2010

Complex transcriptional regulatory networks around the retinoblastoma tumor suppressor gene.

Cell Cycle 2010 May 19;9(9):1663-4. Epub 2010 May 19.

Departments of Pediatrics and Genetics, Cancer Biology Program, Stanford Medical School, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.9.9.11593DOI Listing
May 2010

Regulation of RB transcription in vivo by RB family members.

Mol Cell Biol 2010 Apr 25;30(7):1729-45. Epub 2010 Jan 25.

Department of Pediatrics, Stanford Medical School, 269 Campus Drive, CCSR1215, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.00952-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838078PMC
April 2010

p107 in the public eye: an Rb understudy and more.

Cell Div 2010 Apr 2;5. Epub 2010 Apr 2.

Departments of Pediatrics and Genetics, Stanford Medical School, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1747-1028-5-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861648PMC
April 2010

Keeping an eye on retinoblastoma control of human embryonic stem cells.

J Cell Biochem 2009 Dec;108(5):1023-30

Department of Pediatrics, Stanford Medical School, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.22342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945208PMC
December 2009

The role of the retinoblastoma/E2F1 tumor suppressor pathway in the lesion recognition step of nucleotide excision repair.

DNA Repair (Amst) 2009 Jul 18;8(7):795-802. Epub 2009 Apr 18.

Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA 94305-5151, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dnarep.2009.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700215PMC
July 2009

Cellular mechanisms of tumour suppression by the retinoblastoma gene.

Nat Rev Cancer 2008 Sep;8(9):671-82

Cancer Biology Program, Stanford University School of Medicine, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrc2399DOI Listing
September 2008

GFP reporter mice for the retinoblastoma-related cell cycle regulator p107.

Cell Cycle 2008 Aug 12;7(16):2544-52. Epub 2008 Aug 12.

Department of Pediatrics and Genetics, Cancer Biology Program, Stanford Medical School, Stanford, California, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730771PMC
http://dx.doi.org/10.4161/cc.7.16.6441DOI Listing
August 2008

Hope in sight for retinoblastoma.

Authors:
Julien Sage

Nat Med 2007 Jan;13(1):30-1

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm0107-30DOI Listing
January 2007

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

Genes Dev 2007 Jan;21(1):49-54

Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1499407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1759899PMC
January 2007

The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium.

J Biol Chem 2006 Jan 28;281(1):638-47. Epub 2005 Oct 28.

Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M509053200
Publisher Site
http://dx.doi.org/10.1074/jbc.M509053200DOI Listing
January 2006

C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence.

EMBO J 2005 Sep 18;24(18):3301-12. Epub 2005 Aug 18.

Laboratory of Protein Dynamics and Signaling, NCI-Frederick, Frederick, MD 21702-1201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.emboj.7600789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224679PMC
September 2005

Making young tumors old: a new weapon against cancer?

Authors:
Julien Sage

Sci Aging Knowledge Environ 2005 Aug 17;2005(33):pe25. Epub 2005 Aug 17.

Stanford University School of Medicine, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sageke.2005.33.pe25DOI Listing
August 2005

Cell type-specific effects of Rb deletion in the murine retina.

Genes Dev 2004 Jul 1;18(14):1681-94. Epub 2004 Jul 1.

Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

View Article

Download full-text PDF

Source
http://www.genesdev.org/cgi/doi/10.1101/gad.1203304
Publisher Site
http://dx.doi.org/10.1101/gad.1203304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC478190PMC
July 2004

Cyclin C makes an entry into the cell cycle.

Authors:
Julien Sage

Dev Cell 2004 May;6(5):607-8

Departments of Pediatrics and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
May 2004