Publications by authors named "Julien Lescar"

131Publications

Crystal structure of the periplasmic sensor domain of histidine kinase VbrK suggests indirect sensing of β-lactam antibiotics.

J Struct Biol 2020 Nov 2;212(2):107610. Epub 2020 Sep 2.

Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, 138602, Singapore; NTU Institute of Structural Biology, Nanyang Technological University, 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 637551, Singapore. Electronic address:

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November 2020

Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism.

Biochem Biophys Res Commun 2020 Nov 30;532(3):370-376. Epub 2020 Aug 30.

Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, 138602, Singapore; NTU Institute of Structural Biology, Nanyang Technological University, 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore. Electronic address:

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November 2020

Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3.

Antiviral Res 2020 10 5;182:104900. Epub 2020 Aug 5.

Lee Kong Chian School of Medicine, Nanyang Technological University, EMB 03-07, 59 Nanyang Drive, 636921, Singapore; NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 636921, Singapore. Electronic address:

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October 2020

Tagging Transferrin Receptor with a Disulfide FRET Probe To Gauge the Redox State in Endosomal Compartments.

Anal Chem 2020 09 3;92(18):12460-12466. Epub 2020 Aug 3.

School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore.

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September 2020

Temporal release of a three-component protein subunit vaccine from polymer multilayers.

J Control Release 2020 01 20;317:130-141. Epub 2019 Nov 20.

Interdisciplinary Research Group in Infectious Diseases, Singapore-MIT Alliance for Research and Technology, Singapore; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address:

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January 2020

Structure of the human metapneumovirus polymerase phosphoprotein complex.

Nature 2020 01 7;577(7789):275-279. Epub 2019 Nov 7.

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.

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January 2020

Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis.

J Mol Biol 2019 09 2;431(19):3690-3705. Epub 2019 Aug 2.

Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, 138602, Singapore; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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September 2019

Backbone resonance assignment for the full length tRNA-(NG37) methyltransferase of Pseudomonas aeruginosa.

Biomol NMR Assign 2019 10 7;13(2):327-332. Epub 2019 Jun 7.

Experimental Drug Development Centre, 10 Biopolis Road, #05-01, Singapore, 138670, Singapore.

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October 2019

Structural determinants for peptide-bond formation by asparaginyl ligases.

Proc Natl Acad Sci U S A 2019 06 23;116(24):11737-11746. Epub 2019 May 23.

School of Biological Sciences, Nanyang Technological University, 637551 Singapore;

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June 2019

Pellino1 specifically binds to phospho-Thr18 of p53 and is recruited to sites of DNA damage.

Biochem Biophys Res Commun 2019 06 12;513(3):714-720. Epub 2019 Apr 12.

School of Biological Sciences, Nanyang Technological University, Singapore. Electronic address:

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June 2019