Julie Secombe

Julie Secombe

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Julie Secombe

Julie Secombe

Publications by authors named "Julie Secombe"

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20Publications

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Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance.

Cell Host Microbe 2019 04 19;25(4):537-552.e8. Epub 2019 Mar 19.

Department of Pathogen Biology-Microbiology Division, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, China; Key Laboratory of Pathogen of Jiangsu Province, Center of Global Health, Nanjing Medical University, Nanjing 211166, China; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China; Key Laboratory of Holistic Integrative Enterology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.02.003DOI Listing
April 2019

The Histone Demethylase KDM5 Is Essential for Larval Growth in .

Genetics 2018 07 15;209(3):773-787. Epub 2018 May 15.

Department of Genetics, Albert Einstein College of Medicine, Bronx, New York 10461

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http://dx.doi.org/10.1534/genetics.118.301004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028249PMC
July 2018

A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5.

Cell Rep 2018 02;22(9):2359-2369

Department of Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA; Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854480PMC
February 2018

Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling.

Nat Commun 2016 08 10;7:12331. Epub 2016 Aug 10.

Departamento de Ciências Biomédicas e Medicina, and Center for Biomedical Research, Universidade do Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.

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http://dx.doi.org/10.1038/ncomms12331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987523PMC
August 2016

The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif.

Cell Rep 2015 Dec 7;13(10):2219-31. Epub 2015 Dec 7.

Department of Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247150129
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http://dx.doi.org/10.1016/j.celrep.2015.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684901PMC
December 2015

KDM5 interacts with Foxo to modulate cellular levels of oxidative stress.

PLoS Genet 2014 Oct 16;10(10):e1004676. Epub 2014 Oct 16.

Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199495PMC
October 2014

Myc-dependent genome instability and lifespan in Drosophila.

PLoS One 2013 6;8(9):e74641. Epub 2013 Sep 6.

Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074641PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765364PMC
July 2014

The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth.

Development 2013 Dec 30;140(23):4776-87. Epub 2013 Oct 30.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle 98109, WA, USA.

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http://dx.doi.org/10.1242/dev.096941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833434PMC
December 2013

Myc in stem cell behaviour: insights from Drosophila.

Adv Exp Med Biol 2013 ;786:269-85

Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Melbourne, 3010, VIC, Australia.

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http://dx.doi.org/10.1007/978-94-007-6621-1_15DOI Listing
September 2013

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.

Science 2011 Sep;333(6051):1881-5

Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/science.1206022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204309PMC
September 2011

Essential functions of the histone demethylase lid.

PLoS Genet 2010 Nov 24;6(11):e1001221. Epub 2010 Nov 24.

Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1371/journal.pgen.1001221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991268PMC
November 2010

The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection.

Cell Cycle 2007 Jun 14;6(11):1324-8. Epub 2007 Jun 14.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

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http://dx.doi.org/10.4161/cc.6.11.4269DOI Listing
June 2007

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth.

Genes Dev 2007 Mar 20;21(5):537-51. Epub 2007 Feb 20.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1101/gad.1523007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820896PMC
March 2007

Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.

J Biol Chem 2004 Apr 9;279(17):17126-33. Epub 2004 Feb 9.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

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http://dx.doi.org/10.1074/jbc.M310097200DOI Listing
April 2004

Myc: a weapon of mass destruction.

Cell 2004 Apr;117(2):153-6

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/s0092-8674(04)00336-8DOI Listing
April 2004

Drosophila cyclin E interacts with components of the Brahma complex.

EMBO J 2002 Jul;21(13):3377-89

Peter MacCallum Cancer Institute, Locked bag 1, A'Beckett Street, Melbourne, Victoria 8006, Australia.

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http://dx.doi.org/10.1093/emboj/cdf334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126084PMC
July 2002

Analysis of Drosophila cyclin EI and II function during development: identification of an inhibitory zone within the morphogenetic furrow of the eye imaginal disc that blocks the function of cyclin EI but not cyclin EII.

Dev Biol 2002 Jan;241(1):157-71

Center for the Molecular Genetics of Development and Department of Molecular Biosciences, University of Adelaide, Adelaide, South Australia, 5005, Australia.

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http://dx.doi.org/10.1006/dbio.2001.0496DOI Listing
January 2002