Julie R Brahmer

Julie R Brahmer

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Julie R Brahmer

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Challenge of Rechallenge: When to Resume Immunotherapy Following an Immune-Related Adverse Event.

J Clin Oncol 2019 Oct 28;37(30):2714-2718. Epub 2019 Aug 28.

Johns Hopkins Medicine Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.19.01623DOI Listing
October 2019

The emerging role of epigenetic therapeutics in immuno-oncology.

Nat Rev Clin Oncol 2019 Sep 23. Epub 2019 Sep 23.

Department of Oncology, The Johns Hopkins School of Medicine, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA.

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http://www.nature.com/articles/s41571-019-0266-5
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http://dx.doi.org/10.1038/s41571-019-0266-5DOI Listing
September 2019

Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer.

N Engl J Med 2019 Sep 28. Epub 2019 Sep 28.

From the Memorial Sloan Kettering Cancer Center, New York (M.D.H.); Hospital Universitario Doce de Octubre, Centro Nacional de Investigaciones Oncológicas, Universidad Complutense, and Centro de Investigación Biomédica en Red de Cáncer, Madrid (L.P.-A.), Hospital Universitario Virgen Del Rocio, Seville (R.B.C.), and the Catalan Institute of Oncology-Germans Trias i Pujol Hospital, Badalona (E.C.C.) - all in Spain; Ambulatorium Chemioterapii, Bydgoszcz, Poland (B.Z.); the Asan Medical Center (S.-W.K.) and the Samsung Medical Center at Sungkyunkwan University School of Medicine (K.P.) - both in Seoul, South Korea; the Institute of Oncology Prof. Dr. Alexandru Trestioreanu, Bucharest, Romania (A.A.); the Hospital Italiano de Buenos Aires, Buenos Aires (L.L.); Instituto Jalisciense de Cancerologia, Guadalajara, Mexico (E.M.J.); the Saitama Cancer Center, Saitama, Japan (H.S.); Matrai Gyogyintezet, Matrahaza, Hungary (I.A.); Limoges University Hospital, Limoges (A.V.), and Aix-Marseille University, National Center for Scientific Research, INSERM, Centre de Recherche en Cancérologie de Marseille, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.) - all in France; Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland (S.P.); Sotiria General Hospital, National and Kapodistrian University of Athens, Athens (K.S.); Lung Clinic Grosshansdorf, Airway Research Center North, German Center of Lung Research, Grosshansdorf, Germany (M.R.); Fox Chase Cancer Center, Philadelphia (H.B.); Johns Hopkins Kimmel Cancer Center, Baltimore (J.R.B.); Princess Alexandra Hospital, Brisbane, QLD, Australia (K.J.O.); Bristol-Myers Squibb, Princeton, NJ (W.J.G., P.B., S.K.R., R.S.K., F.E.N.); and Winship Cancer Institute, Emory University, Atlanta (S.S.R.).

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http://dx.doi.org/10.1056/NEJMoa1910231DOI Listing
September 2019

A pooled analysis of two phase II trials evaluating metformin plus platinum-based chemotherapy in advanced non-small cell lung cancer.

Cancer Treat Res Commun 2019 10;20:100150. Epub 2019 May 10.

Johns Hopkins Sidney Kimmel Cancer Center at Sibley Memorial Hospital, Washington, DC, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24682942193004
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http://dx.doi.org/10.1016/j.ctarc.2019.100150DOI Listing
May 2019

Clinical presentation of immune checkpoint inhibitor-induced inflammatory arthritis differs by immunotherapy regimen.

Semin Arthritis Rheum 2018 12 22;48(3):553-557. Epub 2018 Mar 22.

Johns Hopkins University, Division of Rheumatology, 5501 Hopkins Bayview Circle, Suite 1.B.1, Baltimore, MD.

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http://dx.doi.org/10.1016/j.semarthrit.2018.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150859PMC
December 2018

Reply to D.L. Kimpel et al.

J Clin Oncol 2018 09 18;36(26):2744. Epub 2018 Jul 18.

Maria E. Suarez-Almazor, The University of Texas MD Anderson Cancer Center, Houston, TX; John A. Thompson, Seattle Cancer Care Alliance, Seattle, WA; and Julie R. Brahmer, The Johns Hopkins University, Baltimore, MD.

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http://ascopubs.org/doi/10.1200/JCO.2018.79.1798
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http://dx.doi.org/10.1200/JCO.2018.79.1798DOI Listing
September 2018

Treatment of Complications from Immune Checkpoint Inhibition in Patients with Lung Cancer.

Curr Treat Options Oncol 2018 08 13;19(9):46. Epub 2018 Aug 13.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Bayview, Johns Hopkins University, 4940 Eastern Avenue, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1007/s11864-018-0562-9DOI Listing
August 2018

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.

J Clin Oncol 2018 06 14;36(17):1714-1768. Epub 2018 Feb 14.

Julie R. Brahmer, Johns Hopkins Kimmel Cancer Center; Jennifer S. Mammen, Johns Hopkins University, Baltimore, MD; Christina Lacchetti, American Society of Clinical Oncology, Alexandria; Alexander Spira, Virginia Cancer Specialists and US Oncology Research, Fairfax, VA; Bryan J. Schneider, University of Michigan Health System, Ann Arbor, MI; Michael B. Atkins, Georgetown Lombardi Comprehensive Cancer Center; Cristina A. Reichner, Georgetown University; Laura D. Porter, Colon Cancer Alliance; Washington, DC; Kelly J. Brassil, Aung Naing, Loretta J. Nastoupil, Maria E. Suarez-Almazor, and Yinghong Wang, MD Anderson Cancer Center, Houston, TX; Jeffrey M. Caterino, The Ohio State University Wexner Medical Center, Columbus, OH; Ian Chau, The Royal Marsden Hospital and Institute of Cancer Research, London and Surrey, United Kingdom; Marc S. Ernstoff and Igor Puzanov, Roswell Park Cancer Institute, Buffalo; Bianca D. Santomasso and Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center; Jeffrey S. Weber, New York University Langone Medical Center, New York, NY; Pamela Ginex, Oncology Nursing Society, Pittsburgh, PA; Jennifer M. Gardner, Seattle Cancer Care Alliance and University of Washington, Seattle, WA; Sigrun Hallmeyer, Oncology Specialists SC, Park Ridge, IL; Jennifer Holter Chakrabarty, University of Oklahoma, Stephenson Cancer Center, Oklahoma City, OK; Natasha B. Leighl, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; David F. McDermott, Beth Israel Deaconess Medical Center; Carole Seigel, Massachusetts General Hospital Cancer Center, Boston, MA; John A. Thompson, Seattle Cancer Care Alliance, University of Washington, and the Fred Hutchinson Cancer Research Center, Seattle, WA; and Tanyanika Phillips, CHRISTUS St Frances Cabrini Cancer Center, Alexandria, LA.

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http://dx.doi.org/10.1200/JCO.2017.77.6385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481621PMC
June 2018

Neoadjuvant PD-1 Blockade in Resectable Lung Cancer.

N Engl J Med 2018 May 16;378(21):1976-1986. Epub 2018 Apr 16.

From the Bloomberg-Kimmel Institute for Cancer Immunotherapy and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore (P.M.F., K.N.S., V.A., T.R.C., M.Z., S.C.Y., S.B., R.J.B., J.N., K.A.M., F.V., H.G., J.Z., J.X.C., H.Y.C., J.-W.S., R.B.S., J.W., E.G., H.W., G.L.R., J.M.T., V.E.V., S.L.T., J.R.B., D.M.P.); Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine (J.E.C., M.D.H., D.R.J., M.J.V., N.R., Z.O., V.R., J.D.W., T.M.) and the Ludwig Collaborative (J.D.W., T.M.) - all in New York; the Parker Institute for Cancer Immunotherapy, San Francisco (J.D.W., T.M.); and Swim Across America Laboratory, Charlotte, NC (J.D.W., T.M.).

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http://www.nejm.org/doi/10.1056/NEJMoa1716078
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http://dx.doi.org/10.1056/NEJMoa1716078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223617PMC
May 2018

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline Summary.

J Oncol Pract 2018 04 8;14(4):247-249. Epub 2018 Mar 8.

Johns Hopkins Kimmel Cancer Center, Baltimore, MD; American Society of Clinical Oncology, Alexandria, VA; University of Washington; and Fred Hutchinson Cancer Research Center, Seattle, WA.

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http://dx.doi.org/10.1200/JOP.18.00005DOI Listing
April 2018

Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Oncotarget 2017 Nov 20;8(57):96684-96696. Epub 2017 May 20.

Department of Pathology, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA.

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http://dx.doi.org/10.18632/oncotarget.18042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722514PMC
November 2017

Cutaneous Eruptions in Patients Receiving Immune Checkpoint Blockade: Clinicopathologic Analysis of the Nonlichenoid Histologic Pattern.

Am J Surg Pathol 2017 Oct;41(10):1381-1389

Departments of *Dermatology ‡Pathology §Oncology, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center ∥The Brady Urologic Institute, Johns Hopkins University School of Medicine, Baltimore, MD Departments of †Medicine, Thoracic Oncology Service ¶Pathology #Dermatology, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/PAS.0000000000000900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657299PMC
October 2017

Pembrolizumab in Non-Small-Cell Lung Cancer.

N Engl J Med 2017 03;376(10):997

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD

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http://dx.doi.org/10.1056/NEJMc1615559DOI Listing
March 2017

Immune Checkpoint Therapy in Non-Small Cell Lung Cancer.

Cancer J 2016 Mar-Apr;22(2):81-91

From the Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD.

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http://dx.doi.org/10.1097/PPO.0000000000000178DOI Listing
January 2017

Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer.

N Engl J Med 2016 11 8;375(19):1823-1833. Epub 2016 Oct 8.

From Lung Clinic Grosshansdorf, Airway Research Center North, German Center of Lung Research, Grosshansdorf, Germany (M.R.); Hospital Universitario Insular de Gran Canaria, Las Palmas, Spain (D.R.-A.); Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, ON, Canada (A.G.R.); Westmead Hospital and the University of Sydney, Sydney (R.H.), and Southern Medical Day Care Centre, Wollongong, NSW (A.T.) - both in Australia; Jász-Nagykun-Szolnok County Hospital, Szolnok (T.C.), and Országos Korányi TBC és Pulmonológiai Intézet, Budapest (A.F.) - both in Hungary; Meir Medical Center, Kfar-Saba (M.G.), and Davidoff Cancer Center, Tel Aviv University, Petah Tikva (N.P.) - both in Israel; St. James's Hospital and Cancer Trials Ireland, Dublin (S.C.); the Royal Marsden Hospital, Sutton, Surrey, United Kingdom (M.O.); MedStar Franklin Square Hospital (S.R.) and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (J.R.B.) - both in Baltimore; Okayama University Hospital, Okayama, Japan (K.H.); and Merck, Kenilworth, NJ (M.A.L., G.M.L., Y.S., R.R.).

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http://dx.doi.org/10.1056/NEJMoa1606774DOI Listing
November 2016

Immunotherapy for Lung Cancer: No Longer an Abstract Concept.

Semin Respir Crit Care Med 2016 10 12;37(5):771-782. Epub 2016 Oct 12.

Division of Upper Aerodigestive, Department of Oncology, Sidney Kimmel Cancer Center at Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1055/s-0036-1592298DOI Listing
October 2016

Nivolumab in Combination With Platinum-Based Doublet Chemotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2016 09 27;34(25):2969-79. Epub 2016 Jun 27.

Naiyer A. Rizvi and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; Julie R. Brahmer, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Rosalyn A. Juergens, Juravinski Cancer Centre at McMaster University, Hamilton; Scott A. Laurie, Ottawa Hospital Cancer Centre, Ottawa; Frances A. Shepherd, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Hossein Borghaei, Fox Chase Cancer Center, Philadelphia, PA; Scott Gettinger, Yale Cancer Center, New Haven, CT; Laura Q. Chow, University of Washington, Seattle, WA; David E. Gerber, University of Texas Southwestern Medical Center, Dallas, TX; Jonathan W. Goldman, University of California, Los Angeles, Los Angeles, CA; Allen C. Chen, Yun Shen, Faith E. Nathan, and Christopher T. Harbison, Bristol-Myers Squibb, Princeton, NJ; and Scott Antonia, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

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http://ascopubs.org/doi/10.1200/JCO.2016.66.9861
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http://dx.doi.org/10.1200/JCO.2016.66.9861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569693PMC
September 2016

Using Immune Checkpoint Inhibitors in Lung Cancer.

Oncology (Williston Park) 2016 08;30(8):713-21

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August 2016

Identifying and addressing the toxicity of checkpoint inhibitors in lung cancer.

Authors:
Julie R Brahmer

Clin Adv Hematol Oncol 2016 Mar;14(3):165-7

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medicine, Baltimore, Maryland.

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March 2016

Nivolumab: targeting PD-1 to bolster antitumor immunity.

Future Oncol 2015 23;11(9):1307-26. Epub 2015 Mar 23.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.2217/fon.15.52DOI Listing
February 2016

Oligometastatic Adenocarcinoma of the Lung: A Therapeutic Opportunity for Long-Term Survival.

Cureus 2015 Dec 16;7(12):e409. Epub 2015 Dec 16.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins.

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http://dx.doi.org/10.7759/cureus.409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725613PMC
December 2015

Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update.

J Clin Oncol 2015 Oct 31;33(30):3488-515. Epub 2015 Aug 31.

Gregory A. Masters, Helen F. Graham Cancer Center, Newark, DE; Sarah Temin, American Society of Clinical Oncology, Alexandria; Sherman Baker Jr, Virginia Commonwealth University; David Trent, Virginia Cancer Center, Richmond, VA; Christopher G. Azzoli, Massachusetts General Hospital Cancer Center, Boston, MA; Giuseppe Giaccone, Lombardi Cancer Center, Georgetown University, Washington, DC; Julie R. Brahmer and Thomas J. Smith, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; Peter M. Ellis, Juravinski Cancer Centre, Hamilton, Ontario, Canada; Ajeet Gajra, Upstate Medical University, Syracuse, NY; Nancy Rackear, Uniting Against Lung Cancer, Fort Lauderdale, FL; Joan H. Schiller, University of Texas Southwestern; David H. Johnson, University of Texas Southwestern Medical Center at Dallas, Dallas; and John R. Strawn, patient representative, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2015.62.1342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019421PMC
October 2015

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.

N Engl J Med 2015 Oct 27;373(17):1627-39. Epub 2015 Sep 27.

From the Fox Chase Cancer Center, Philadelphia (H.B.); Hospital Universitario Virgen del Rocio, Seville (L.P.-A.), Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona (E.F.), and Hospital de Madrid, Norte Sanchinarro, Madrid (E.H.) - all in Spain; Vanderbilt-Ingram Cancer Center (L.H.), and Sarah Cannon Research Institute and Tennessee Oncology (D.R.S.) - both in Nashville; Thoraxklinik, Heidelberg University Hospital, Heidelberg (M.S.) and Robert-Bosch-Krankenhaus Stuttgart, Gerlingen (M.K.) - both in Germany; Duke University Medical Center, Durham, NC (N.E.R.); University of Washington, Seattle (L.Q.C.); University of Chicago Medicine and Biological Sciences, Chicago (E.E.V.); Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.), Centre Léon Bérard, Lyon (J.F.), and Centre Hospitalier Universitaire de Rennes, Rennes (H.L.) - all in France; Instituto Nacional de Cancerologia, Mexico City (O.A.); Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS, Meldola, Forlì-Cesena (M.A.B.), and Ospedale di Perugia, Perugia (L.C.) - both in Italy; N.N. Blokhin Russian Cancer Research Center, Moscow (E.P.); University of Texas Southwestern Medical Center, Dallas (D.E.G.); Yale Comprehensive Cancer Center, New Haven, CT (S.N.G.); Memorial Sloan Kettering Cancer Center, New York (C.M.R., N.R.); University of Texas M.D. Anderson Cancer Center, Houston (G.R.B.); H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (S.J.A.); Bristol-Myers Squibb, Princeton, NJ (C.D., C.T.H., F.G.F.); and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore (J.R.B.).

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http://dx.doi.org/10.1056/NEJMoa1507643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705936PMC
October 2015

Survival, Durable Response, and Long-Term Safety in Patients With Previously Treated Advanced Renal Cell Carcinoma Receiving Nivolumab.

J Clin Oncol 2015 Jun 30;33(18):2013-20. Epub 2015 Mar 30.

David F. McDermott, Beth Israel Deaconess Medical Center; Toni K. Choueiri, Dana-Farber Cancer Institute/Brigham and Women's Hospital; Igor Puzanov and F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Charles G. Drake, Julie R. Brahmer, Hans J. Hammers, Suzanne L. Topalian, and Drew M. Pardoll, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; Mario Sznol, Yale University School of Medicine and Smilow Cancer Center, Yale-New Haven Hospital, New Haven, CT; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; David C. Smith, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Richard D. Carvajal, Memorial Sloan-Kettering Cancer Center, New York, NY; Jon M. Wigginton, Georgia D. Kollia, Ashok Gupta, Dan McDonald, and Vindira Sankar, Bristol-Myers Squibb, Princeton, NJ; Jeffrey A. Sosman, Vanderbilt-Ingram Cancer Center, Nashville, TN; and Michael B. Atkins, Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC.

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http://dx.doi.org/10.1200/JCO.2014.58.1041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517051PMC
June 2015

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2015 Jun 20;33(18):2004-12. Epub 2015 Apr 20.

Scott N. Gettinger and Mario Sznol, Yale Cancer Center, New Haven, CT; Leora Horn, David P. Carbone, and Jeffrey A. Sosman, Vanderbilt University Medical Center; David R. Spigel, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Leena Gandhi, David M. Jackman, and F. Stephen Hodi, Dana-Farber Cancer Institute; Rebecca S. Heist and Lecia V. Sequist, Massachusetts General Hospital Cancer Center; David F. McDermott, Beth Israel Deaconess Medical Center, Boston, MA; Scott J. Antonia and Mary C. Pinder-Schenck, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Naiyer A. Rizvi, Richard D. Carvajal, and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; David C. Smith, University of Michigan, Ann Arbor, MI; Philip Leming, Christ Hospital Cancer Center, Cincinnati, OH; Suzanne L. Topalian, Drew M. Pardoll, and Julie R. Brahmer, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; and Vindira Sankar, Christoph M. Ahlers, Mark Salvati, Jon M. Wigginton, Georgia D. Kollia, and Ashok K. Gupta, Bristol-Myers Squibb, Princeton, NJ.

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http://jco.ascopubs.org/content/early/2015/04/15/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.3708
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http://dx.doi.org/10.1200/JCO.2014.58.3708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672027PMC
June 2015

Immune checkpoint modulation for non-small cell lung cancer.

Clin Cancer Res 2015 May;21(10):2256-62

Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2959DOI Listing
May 2015

Cancer immunotherapy: a future paradigm shift in the treatment of non-small cell lung cancer.

Clin Cancer Res 2015 Mar;21(5):976-84

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1187DOI Listing
March 2015

Nivolumab in NSCLC: latest evidence and clinical potential.

Ther Adv Med Oncol 2015 Mar;7(2):85-96

Department of Haematology-Oncology, National University Cancer Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228.

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http://journals.sagepub.com/doi/10.1177/1758834014567470
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http://dx.doi.org/10.1177/1758834014567470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346216PMC
March 2015

Harnessing the power of the immune system via blockade of PD-1 and PD-L1: a promising new anticancer strategy.

Immunotherapy 2014 ;6(4):459-75

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Cancer Research Building I, Room 186, 401 North Broadway Street, Baltimore, MD 21287, USA.

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https://www.futuremedicine.com/doi/10.2217/imt.14.9
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http://dx.doi.org/10.2217/imt.14.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732706PMC
December 2014

What lies within: novel strategies in immunotherapy for non-small cell lung cancer.

Oncologist 2013 8;18(11):1203-13. Epub 2013 Oct 8.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1634/theoncologist.2013-0171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825306PMC
October 2014

Immunotherapy in the treatment of non-small cell lung cancer.

Lung Cancer 2014 Aug 14;85(2):101-9. Epub 2014 May 14.

Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Surgery, University of Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2014.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332778PMC
August 2014

Reply: Regulatory T cells-an important target for cancer immunotherapy.

Nat Rev Clin Oncol 2014 Jun 29;11(6):307. Epub 2014 Apr 29.

Department of Oncology, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1038/nrclinonc.2013.208-c2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732695PMC
June 2014

New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer.

Clin Cancer Res 2014 May 18;20(9):2244-8. Epub 2014 Mar 18.

Authors' Affiliation: Upper Aerodigestive Malignancies Division, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325981PMC
May 2014

Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab.

J Clin Oncol 2014 Apr 3;32(10):1020-30. Epub 2014 Mar 3.

Suzanne L. Topalian, William H. Sharfman, Julie R. Brahmer, Evan J. Lipson, Janis M. Taube, and Drew M. Pardoll, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Mario Sznol and Harriet M. Kluger, Yale University School of Medicine and Smilow Cancer Center, Yale-New Haven Hospital, New Haven, CT; David F. McDermott, Beth Israel Deaconess Medical Center; Donald P. Lawrence, Massachusetts General Hospital Cancer Center; F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Richard D. Carvajal, Memorial Sloan-Kettering Cancer Center, New York, NY; Michael B. Atkins, Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; Philip D. Leming, The Christ Hospital Cancer Center, Cincinnati, OH; Igor Puzanov and Jeffrey A. Sosman, Vanderbilt University Medical Center, Nashville, TN; David C. Smith, University of Michigan, Ann Arbor, MI; and Jon M. Wigginton, Georgia D. Kollia, and Ashok Gupta, Bristol-Myers Squibb, Princeton, NJ.

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http://dx.doi.org/10.1200/JCO.2013.53.0105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811023PMC
April 2014

New strategies in lung cancer: translating immunotherapy into clinical practice.

Clin Cancer Res 2014 Mar 27;20(5):1067-73. Epub 2014 Jan 27.

Authors' Affiliation: Upper Aerodigestive Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0731DOI Listing
March 2014

Systemic therapy, clinical outcomes, and overall survival in locally advanced or metastatic pulmonary carcinoid: a brief report.

J Thorac Oncol 2014 Mar;9(3):414-8

Departments of *Medical Oncology, †Surgery, and ‡Pathology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland; and §Medical Oncology Branch, National Cancer Institute, Bethesda, Maryland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322909PMC
March 2014

Immune checkpoint blockade: the hope for immunotherapy as a treatment of lung cancer?

Authors:
Julie R Brahmer

Semin Oncol 2014 Feb 12;41(1):126-32. Epub 2013 Dec 12.

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2013.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732704PMC
February 2014

Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer.

Nat Rev Clin Oncol 2014 Jan 19;11(1):24-37. Epub 2013 Nov 19.

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Bunting Blaustein Cancer Research Building, 1650 Orleans Street, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1038/nrclinonc.2013.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086654PMC
January 2014

Targeting the immune system in the treatment of non-small-cell lung cancer.

Curr Treat Options Oncol 2013 Dec;14(4):580-94

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at The Johns Hopkins Hospital, Bunting-Blaustein Cancer Research Building 1, 1650 Orleans St., Room 186, Baltimore, MD, 21287, USA,

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http://dx.doi.org/10.1007/s11864-013-0250-8DOI Listing
December 2013

Immune checkpoint inhibitors: making immunotherapy a reality for the treatment of lung cancer.

Cancer Immunol Res 2013 Aug 22;1(2):85-91. Epub 2013 Jul 22.

Authors' Affiliation: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856021PMC
August 2013

Harnessing the immune system for the treatment of non-small-cell lung cancer.

Authors:
Julie R Brahmer

J Clin Oncol 2013 Mar 11;31(8):1021-8. Epub 2013 Feb 11.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.

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http://ascopubs.org/doi/10.1200/JCO.2012.45.8703
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March 2013

Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody.

Clin Cancer Res 2013 Jan 20;19(2):462-8. Epub 2012 Nov 20.

Department of Oncology, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-2625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548952PMC
January 2013

PD-1-targeted immunotherapy: recent clinical findings.

Authors:
Julie R Brahmer

Clin Adv Hematol Oncol 2012 Oct;10(10):674-5

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.

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October 2012

Antiangiogenic agents in combination with chemotherapy in patients with advanced non-small cell lung cancer.

Cancer Invest 2011 May;29(4):325-37

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University Hospital, Baltimore, Maryland, USA.

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http://dx.doi.org/10.3109/07357907.2011.554476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082199PMC
May 2011

Clinical course of advanced non-small-cell lung cancer patients experiencing hypertension during treatment with bevacizumab in combination with carboplatin and paclitaxel on ECOG 4599.

J Clin Oncol 2010 Feb 19;28(6):949-54. Epub 2010 Jan 19.

Department of Biostatistics and Computational Biology, CLSB 11007, Dana-Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA.

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http://ascopubs.org/doi/10.1200/JCO.2009.25.4482
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http://dx.doi.org/10.1200/JCO.2009.25.4482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834434PMC
February 2010

Concordance of cancer patients' function, symptoms, and supportive care needs.

Qual Life Res 2009 Oct 6;18(8):991-8. Epub 2009 Aug 6.

Johns Hopkins School of Medicine, 624 N. Broadway, Room 657, Baltimore, MD 21205, USA.

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October 2009

Chemotherapy for advanced stage non-small cell lung cancer.

Semin Thorac Cardiovasc Surg 2008 ;20(3):210-6

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231-1000, USA.

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http://dx.doi.org/10.1053/j.semtcvs.2008.09.002DOI Listing
March 2009

Optimizing the dose and schedule of anti-vascular endothelial growth factor antibodies in non-small-cell lung cancer.

Clin Lung Cancer 2008 Mar;9 Suppl 2:S51-6

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.3816/CLC.2008.s.008DOI Listing
March 2008