Publications by authors named "Julie L Boerner"

29Publications

Role of TET1 and 5hmC in an Obesity-Linked Pathway Driving Cancer Stem Cells in Triple-Negative Breast Cancer.

Mol Cancer Res 2020 Sep 10. Epub 2020 Sep 10.

Barbara Ann Karmanos Cancer Institute and Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan.

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http://dx.doi.org/10.1158/1541-7786.MCR-20-0359DOI Listing
September 2020

Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer.

Breast Cancer Res 2020 04 15;22(1):37. Epub 2020 Apr 15.

Department of Oncology, Karmanos Cancer Institute Wayne State University, 4100 John R Street, Detroit, MI, 48201, USA.

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http://dx.doi.org/10.1186/s13058-020-01270-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160960PMC
April 2020

Downregulation of Rap1Gap: A Switch from DCIS to Invasive Breast Carcinoma via ERK/MAPK Activation.

Neoplasia 2018 09 22;20(9):951-963. Epub 2018 Aug 22.

Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2018.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106701PMC
September 2018

Abrogating phosphorylation of eIF4B is required for EGFR and mTOR inhibitor synergy in triple-negative breast cancer.

Breast Cancer Res Treat 2014 Sep 17;147(2):283-93. Epub 2014 Aug 17.

Departments of Oncology, Wayne State University, 4100 John R. St, Detroit, MI, 48201, USA.

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http://link.springer.com/10.1007/s10549-014-3102-8
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http://dx.doi.org/10.1007/s10549-014-3102-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171954PMC
September 2014

A targeted enzyme approach to sensitization of tyrosine kinase inhibitor-resistant breast cancer cells.

Exp Cell Res 2012 Oct 8;318(16):2014-21. Epub 2012 Jun 8.

Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

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http://dx.doi.org/10.1016/j.yexcr.2012.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858180PMC
October 2012

Src family kinases mediate epidermal growth factor receptor signaling from lipid rafts in breast cancer cells.

Cancer Biol Ther 2011 Oct 15;12(8):718-26. Epub 2011 Oct 15.

Department of Pharmacology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.

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http://dx.doi.org/10.4161/cbt.12.8.16907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218526PMC
October 2011

Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.

J Cell Physiol 2011 Sep;226(9):2316-28

Department of Pharmacology, Wayne State University, Detroit, Michigan, USA.

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http://dx.doi.org/10.1002/jcp.22570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103760PMC
September 2011

EGFR/Met association regulates EGFR TKI resistance in breast cancer.

J Mol Signal 2010 Jul 12;5. Epub 2010 Jul 12.

Karmanos Cancer Institute at Wayne State University, John R, St, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1186/1750-2187-5-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911419PMC
July 2010

Epidermal growth factor receptor translocation to the mitochondria: regulation and effect.

J Biol Chem 2009 Dec 19;284(52):36592-604. Epub 2009 Oct 19.

Department of Microbiology and the Cancer Center, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1074/jbc.M109.000760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794774PMC
December 2009

RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia.

Blood 2009 Sep 28;114(13):2744-52. Epub 2009 Jul 28.

Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1182/blood-2008-09-179812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756129PMC
September 2009

Role of Src family kinases in acquired resistance to EGFR therapies in cancer.

Authors:
Julie L Boerner

Cancer Biol Ther 2009 Apr;8(8):704-6

Karmanos Cancer Institute and Department of Pharmacology, Wayne State University, Detroit, MI 48201 USA.

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http://dx.doi.org/10.4161/cbt.8.8.8183DOI Listing
April 2009

Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells.

Mol Cancer Res 2007 Aug 1;5(8):847-61. Epub 2007 Aug 1.

Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-06-0427DOI Listing
August 2007

Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis.

Mol Carcinog 2005 Dec;44(4):262-73

Department of Microbiology, The Cancer Center, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1002/mc.20138DOI Listing
December 2005

Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II.

Mol Cell Biol 2004 Aug;24(16):7059-71

Department of Microbiology and Cancer Center, University of Virginia Health System, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1128/MCB.24.16.7059-7071.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC479738PMC
August 2004

Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.

Oncogene 2003 Oct;22(43):6679-89

Tumor Biology Program, Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First St SW, Rochester, MI 55905, USA.

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http://www.nature.com/articles/1206830
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http://dx.doi.org/10.1038/sj.onc.1206830DOI Listing
October 2003

Ligand-independent oncogenic signaling by the epidermal growth factor receptor: v-ErbB as a paradigm.

Exp Cell Res 2003 Mar;284(1):111-21

Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/s0014-4827(02)00096-4DOI Listing
March 2003

STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor.

J Biol Chem 2003 Jan 11;278(3):1671-9. Epub 2002 Nov 11.

Departments of Internal Medicine and Microbiology and the Cancer Center, University of Virginia Health System, Charlottesville, Virginia 22908.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M207289200
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http://dx.doi.org/10.1074/jbc.M207289200DOI Listing
January 2003