Julie C Fitzgerald

Julie C Fitzgerald

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Major Adverse Kidney Events in Pediatric Sepsis.

Clin J Am Soc Nephrol 2019 May 18;14(5):664-672. Epub 2019 Apr 18.

Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.2215/CJN.12201018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500940PMC
May 2019

Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis.

J Surg Res 2019 May 7;242:100-110. Epub 2019 May 7.

Division of Critical Care Medicine, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.

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https://linkinghub.elsevier.com/retrieve/pii/S00224804193019
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http://dx.doi.org/10.1016/j.jss.2019.04.011DOI Listing
May 2019

Vancomycin Prescribing and Therapeutic Drug Monitoring in Children With and Without Acute Kidney Injury After Cardiac Arrest.

Paediatr Drugs 2019 Apr;21(2):107-112

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, 3401 Civic Center Blvd, 6th Floor Wood Building, Room 6117, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s40272-019-00328-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526504PMC
April 2019

Comparison of Methods for Identification of Pediatric Severe Sepsis and Septic Shock in the Virtual Pediatric Systems Database.

Crit Care Med 2019 Feb;47(2):e129-e135

Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000003541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336511PMC
February 2019

Risk factors and inpatient outcomes associated with acute kidney injury at pediatric severe sepsis presentation.

Pediatr Nephrol 2018 Oct 14;33(10):1781-1790. Epub 2018 Jun 14.

Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s00467-018-3981-8DOI Listing
October 2018

Hospital Variation in Intensive Care Resource Utilization and Mortality in Newly Diagnosed Pediatric Leukemia.

Pediatr Crit Care Med 2018 06;19(6):e312-e320

Division of Pediatric Critical Care Medicine, Department of Pediatrics and Public Health Sciences, Penn State Hershey Milton S. Hershey Medical Center, Hershey, PA.

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http://dx.doi.org/10.1097/PCC.0000000000001525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986594PMC
June 2018

Taking meaning from numbers in regional epidemiological data.

Lancet Child Adolesc Health 2018 06 28;2(6):381-382. Epub 2018 Apr 28.

Division of Pediatric Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Pediatric Sepsis Program at the Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(18)30132-9DOI Listing
June 2018

Hypofibrinogenemia Is Associated With Poor Outcome and Secondary Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome in Pediatric Severe Sepsis.

Pediatr Crit Care Med 2018 05;19(5):397-405

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://Insights.ovid.com/crossref?an=00130478-201805000-0000
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http://dx.doi.org/10.1097/PCC.0000000000001507DOI Listing
May 2018

Site Variability in Regulatory Oversight for an International Study of Pediatric Sepsis.

Pediatr Crit Care Med 2018 Apr;19(4):e180-e188

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/PCC.0000000000001455DOI Listing
April 2018

Improving Recognition of Pediatric Severe Sepsis in the Emergency Department: Contributions of a Vital Sign-Based Electronic Alert and Bedside Clinician Identification.

Ann Emerg Med 2017 Dec 2;70(6):759-768.e2. Epub 2017 Jun 2.

Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.annemergmed.2017.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698118PMC
December 2017

High Levels of Morbidity and Mortality Among Pediatric Hematopoietic Cell Transplant Recipients With Severe Sepsis: Insights From the Sepsis PRevalence, OUtcomes, and Therapies International Point Prevalence Study.

Pediatr Crit Care Med 2017 Dec;18(12):1114-1125

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1097/PCC.0000000000001338DOI Listing
December 2017

Identifying Risk for Acute Kidney Injury in Infants and Children Following Cardiac Arrest.

Pediatr Crit Care Med 2017 Oct;18(10):e446-e454

1Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 2Division of Nephrology, Hypertension, and Pheresis, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 3Department of Surgery, Washington University School of Medicine, St. Louis, MO. 4Department of Political Science, Washington University School of Medicine, St. Louis, MO. 5Department of Biostatistics, Washington University School of Medicine, St. Louis, MO. 6Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 7Department of Neurology, Washington University School of Medicine, St. Louis, MO. 8Department of Pediatrics, University of Utah, Salt Lake City, UT. 9Division of Critical Care Medicine, Department of Pediatrics, CS Mott Children's Hospital, University of Michigan, Ann Arbor, MI. 10Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1097/PCC.0000000000001280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628129PMC
October 2017

The Epidemiology of Hospital Death Following Pediatric Severe Sepsis: When, Why, and How Children With Sepsis Die.

Pediatr Crit Care Med 2017 Sep;18(9):823-830

1Division of Critical Care Medicine, Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Division of Emergency Medicine, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 3Division of Critical Care Medicine, Nationwide Children's Hospital, The Ohio State University School of Medicine, Columbus, OH. 4Division of Pediatric Critical Care Medicine, Department of Pediatrics, Penn State Hershey Children's Hospital, Penn State University College of Medicine, Hershey, PA.

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http://Insights.ovid.com/crossref?an=00130478-201709000-0000
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http://dx.doi.org/10.1097/PCC.0000000000001222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581233PMC
September 2017

The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary.

Pediatr Crit Care Med 2017 09;18(9):884-890

1No institution affiliation. 2Department of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 3Department of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 4Department of Pediatric Critical Care, Riley Hospital for Children, Indiana University, Bloomington, IN. 5Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 6Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX. 7Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX. 8Pediatric Critical Care Medicine, Covenant Women and Children's Hospital, Texas Tech University, Lubbock, TX. 9Department of Pediatrics, Division of Pediatric Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL. 10Division of Pediatric Critical Care, University of British Columbia, Vancouver, BC, Canada. 11Department of Pediatrics, Division of Pediatric Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI. 12Department of Pediatrics, Baylor College of Medicine, Houston, TX. 13Department of Pediatrics, Saint Barnabas Medical Center, Livingston, NJ. 14Division of Emergency Medicine and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 15Intensive Care & Bioethics, Great Ormond St Hospital for Sick Children, London, United Kingdom. 16Pediatric Critical Care Medicine, Department of Pediatrics, Stollery Children's Hospital/University of Alberta, Edmonton, AB, Canada. 17Department of Pediatrics, Division of Pediatric Critical Care Medicine, Duke Children's, Durham, NC. 18Departments of Pediatrics and Critical Care, Clinical Epidemiology and Biostatistics, McMaster University, Pediatric Intensive Care Unit, McMaster Children's Hospital, Hamilton, ON, Canada. 19Beth Israel Medical Center, Hartsdale, NY. 20Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI. 21Departments of Pediatrics and Biochemistry, Washington University in Saint Louis School of Medicine, St. Louis, MO. 22Department of Pediatrics, Centre mère-enfant Soleil du CHU de Québec-Université Laval, Québec City, QC, Canada. 23Department of Inpatient Pediatrics, Kaiser Santa Clara Medical Center, Santa Clara, CA. 24Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine and The Children's Hospital of Philadelphia, Philadelphia, PA. 25Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Mott C.S. Children's Hospital, Ann Arbor, MI. 26Division of Critical Care, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA. 27Department of Pediatrics-Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD. 28Division of Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, NY. 29Department of Pediatrics, Division of Critical Care Medicine, Nationwide Children's Hospital, Columbus, OH. 30Department of Critical Care Medicine, Children's Mercy Hospital, Kansas City, MO. 31Department of Pediatrics, Texas Tech University Health Sciences Center, El Paso, TX. 32Division of Pediatric Critical Care, University of Florida, Jacksonville, FL 33Bon Secours St. Mary's Hospital, Glen Allen, VA. 34Department of Pediatrics/Division of Pediatric Critical Care, University of Rochester School of Medicine and Dentistry, Rochester, NY. 35Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. 36Department of Pediatrics, Division of Critical Care, Stanford University School of Medicine, Palo Alto, CA. 37Pediatric Critical Care Medicine, The Children's Hospital at Montefiore, The Pediatric Hospital for Albert Einstein College of Medicine, Bronx, NY. 38Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada. 39Department of Pediatrics, Naval Medical Center San Diego and University of California San Diego School of Medicine, San Diego, CA. 40Department of Pediatrics and Pediatric Critical Care Medicine, The Valley Hospital, Ridgewood, NJ. 41Cardiothoracic ICU, National University Hospital, Singapore. 42Paediatric ICU, The Royal Children's Hospital, Parkville, VIC, Australia. 43Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia. 44Children's Hospital of Pittsburgh, Pittsburgh, PA. 45Department of Pediatrics, Medical College of Georgia at Augusta University, Augusta, GA. 46Department of Pediatrics, Division of Critical Care Medicine, University of Michigan, Ann Arbor, MI. 47Department of Pharmacy Practice, Loma Linda University School of Pharmacy, Loma Linda, CA. 48Division of Emergency Medicine, Ann and Robert Lurie Children's Hospital of Chicago, Feinberg School of Medicine at Northwestern University, Chicago, IL. 49UCL Great Ormond Street Institute of Child Health and Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children, NHS Trust, London, United Kingdom. 50Pediatric Intensive Care and Emergency Services, Apollo Children's Hospital, Chennai, India. 51Department of Pediatrics, Division of Pediatric Critical Care, Duke University School of Nursing and School of Medicine, Durham, NC. 52Pediatrics School of Medicine, Austral University, Pcia de Buenos Aires, Argentina. 53Departments of Pediatrics and Emergency Medicine, University of Colorado School of Medicine, Aurora, CO. 54Critical Care and Transport, Nemours Children's Hospital, Orlando, FL. 55Department of Pediatrics, Critical Care Medicine, Albert Einstein College of Medicine, Bronx, NY. 56Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 57Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Washington School of Medicine, Seattle, WA. 58Departments of Pediatrics & Anesthesiology, Sinai Hospital/NAPA, Baltimore, MD. 59Department of Pediatrics, University of Maryland Medical School, Baltimore, MD.

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http://dx.doi.org/10.1097/PCC.0000000000001259DOI Listing
September 2017

Sepsis-associated in-hospital cardiac arrest: Epidemiology, pathophysiology, and potential therapies.

J Crit Care 2017 08 31;40:128-135. Epub 2017 Mar 31.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34th Street & Civic Center Boulevard, Suite 8566, Philadelphia 19104, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2017.03.023DOI Listing
August 2017

Response to letter to the editor: Sepsis-associated in-hospital cardiac arrest.

J Crit Care 2017 08 21;40:291. Epub 2017 Jun 21.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34(th) Street & Civic Center Boulevard, Suite 8566, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2017.05.037DOI Listing
August 2017

Association of Delayed Antimicrobial Therapy with One-Year Mortality in Pediatric Sepsis.

Shock 2017 07;48(1):29-35

*Division of Critical Care Medicine, Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania †Division of Emergency Medicine, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania ‡McCourt School of Public Policy and Department of Government, Georgetown University, Washington DC §Division of Emergency Medicine, Department of Pediatrics, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois ||Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania ¶Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania #Division of Pediatric Critical Care Medicine, Penn State Hershey Children's Hospital, Penn State University College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1097/SHK.0000000000000833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468469PMC
July 2017

American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock.

Crit Care Med 2017 06;45(6):1061-1093

1No institution affiliation. 2Department of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 3Department of Pediatric Critical Care, Riley Hospital for Children, Indiana University, IN. 4Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 5Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX. 6Pediatric Critical Care Medicine, Covenant Women and Children's Hospital, Texas Tech University, Lubbock, TX. 7Division of Pediatric Critical Care Medicine, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL. 8Division of Pediatric Critical Care, University of British Columbia, Vancouver, BC, Canada. 9Division of Pediatric Critical Care Medicine, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI. 10Department of Pediatrics, Baylor College of Medicine, Houston, TX. 11Department of Pediatrics, Saint Barnabas Medical Center, Livingston, NJ. 12Division of Emergency Medicine and Center for Pediatric Clinical Effectiveness, University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA. 13Intensive Care & Bioethics, Great Ormond St Hospital for Sick Children, London, United Kingdom. 14Pediatric Critical Care Medicine, Department of Pediatrics, Stollery Children's Hospital/University of Alberta, Edmonton, AB, Canada. 15Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke Children's, Durham, NC. 16Departments of Pediatrics and Critical Care, Clinical Epidemiology and Biostatistics, McMaster University, Pediatric Intensive Care Unit, McMaster Children's Hospital, Hamilton, ON, Canada. 17Beth Israel Medical Center, Hartsdale, NY. 18Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI. 19Departments of Pediatrics and Biochemistry, Washington University in Saint Louis School of Medicine, Saint Louis, MO. 20Department of Pediatrics, Centre mère-enfant Soleil du CHU de Québec-Université Laval, Québec City, QC, Canada. 21Department of Inpatient Pediatrics, Kaiser Santa Clara Medical Center, Santa Clara, CA. 22Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA. 23Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Mott C.S. Children's Hospital, Ann Arbor, MI. 24Division of Critical Care, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA. 25Department of Pediatrics-Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD. 26Division of Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, NY. 27Division of Critical Care Medicine, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH. 28Department of Critical Care Medicine, Children's Mercy Hospital, Kansas City, MO. 29Department of Pediatrics, Texas Tech University Health Sciences Center, El Paso, TX. 30Division of Pediatric Critical Care, University of Florida, Jacksonville, FL. 31Bon Secours St. Mary's Hospital, Glen Allen, VA. 32Division of Pediatric Critical Care, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY. 33Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. 34Division of Critical Care, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA. 35Pediatric Critical Care Medicine, The Children's Hospital at Montefiore, The Pediatric Hospital for Albert Einstein College of Medicine, Bronx, NY. 36Department of Pediatrics, University of British Columbia, UBC & BC Children's Hospital Professor in Critical Care-Global Child Health, Vancouver, BC, Canada. 37Department of Pediatrics, Naval Medical Center San Diego and University of California San Diego School of Medicine, San Diego, CA. 38Department of Pediatrics and Pediatric Critical Care Medicine, The Valley Hospital, Ridgewood, NJ. 39Cardiothoracic ICU, National University Hospital, Singapore. 40Paediatric ICU, The Royal Children's Hospital, Melbourne, Australia. 41Department of Paediatrics, University of Melbourne, Melbourne, Australia. 42Children's Hospital of Pittsburgh, Pittsburgh, PA. 43Department of Pediatrics, Medical College of Georgia at Augusta University, Augusta, GA. 44Division of Critical Care Medicine, Department of Pediatrics, University of Michigan, Ann Arbor, MI. 45Department of Pharmacy Practice, Loma Linda University School of Pharmacy, Loma Linda, CA. 46Division of Emergency Medicine, Ann and Robert Lurie Children's Hospital of Chicago, Feinberg School of Medicine at Northwestern University, Chicago, IL. 47UCL Great Ormond Street Institute of Child Health and Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children, NHS Trust, London, United Kingdom. 48Pediatric Intensive Care and Emergency Services, Apollo Children's Hospital, Chennai, India. 49Division of Pediatric Critical Care, Department of Pediatrics, Duke University School of Nursing and School of Medicine, Durham, NC. 50Pediatrics School of Medicine, Austral University, Pcia de Buenos Aires, Argentina. 51Departments of Pediatrics and Emergency Medicine, University of Colorado School of Medicine, Aurora, CO. 52Critical Care and Transport, Nemours Children's Hospital, Orlando, FL. 53Department of Pediatrics, Critical Care Medicine, Albert Einstein College of Medicine, Bronx, NY. 54Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. 55Departments of Pediatrics & Anesthesiology, Sinai Hospital/NAPA, Baltimore, MD. 56Department of Pediatrics, University of Maryland Medical School, Baltimore, MD.

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http://dx.doi.org/10.1097/CCM.0000000000002425DOI Listing
June 2017

The authors reply.

Pediatr Crit Care Med 2017 05;18(5):501-502

Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO; Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA; Division of Critical Care Medicine, Department of Pediatrics, University of Montreal, Montreal, QC, Canada; Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA; Pediatric Critical Care Medicine, Departments of Pediatrics and Public Health Sciences, Penn State University College of Medicine, Hershey, PA; Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA; for the Sepsis Prevalence, Outcomes, and Therapy Study.

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http://dx.doi.org/10.1097/PCC.0000000000001158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506827PMC
May 2017

Pediatric Acute Respiratory Distress Syndrome in Pediatric Allogeneic Hematopoietic Stem Cell Transplants: A Multicenter Study.

Pediatr Crit Care Med 2017 Apr;18(4):304-309

1Division of Critical Care, Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis IN. 2Division of Pediatric Critical Care Medicine, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA. 3Division of Critical Care, Department of Pediatrics, Masonic Children's Hospital, University of Minnesota, Minneapolis, MN. 4Division of Critical Care, Department of Pediatrics, St. Jude's Children's Research Hospital, Memphis, TN. 5Division of Critical Care, Department of Pediatrics, Joseph M Sanzari Children's Hospital at Hackensack University Medical Center, Bergen County, NJ. 6Division of Critical Care, Department of Anesthesia, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 7Department of Biostatistics, Indiana University, Indianapolis IN. 8Division of Critical Care, Department of Pediatrics, Weil Cornell Medical College, New York Presbyterian Hospital, New York City, NY. 9Division of Oncology, Department of Pediatrics, Dana-Farber Cancer Institute Harvard University, Boston, MA. 10Division of Oncology, Department of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY. 11Division of Blood and Marrow Transplant, Department of Pediatrics, Duke Children's Hospital, Duke University, Durham, NC. 12Division of Critical Care, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, OH. 13Division of Critical Care, Department of Pediatrics, Penn State Hershey Children's Hospital, Pennsylvania State University College of Medicine, Hershey, PA. 14Division of Critical Care, Department of Pediatrics, Duke Children's Hospital, Duke University, Durham, NC.

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http://dx.doi.org/10.1097/PCC.0000000000001061DOI Listing
April 2017

Crystalloid Fluid Choice and Clinical Outcomes in Pediatric Sepsis: A Matched Retrospective Cohort Study.

J Pediatr 2017 03 4;182:304-310.e10. Epub 2017 Jan 4.

Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Philadelphia, PA; Division of Infectious Diseases, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.jpeds.2016.11.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525152PMC
March 2017

Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

Crit Care Med 2017 Feb;45(2):e124-e131

1Division of Critical Care Medicine, Department of Anesthesia and Critical Care, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 3Center for Cellular Immunotherapies, Department of Pathology and Laboratory Medicine, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 4Department of Biostatistics and Epidemiology, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 5Division of Hematology-Oncology, Department of Medicine, Abramson Cancer Center, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000002053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452983PMC
February 2017

New or Progressive Multiple Organ Dysfunction Syndrome in Pediatric Severe Sepsis: A Sepsis Phenotype With Higher Morbidity and Mortality.

Pediatr Crit Care Med 2017 01;18(1):8-16

1Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.2Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.3Division of Critical Care Medicine, Department of Pediatrics, University of Montreal, Montreal, QC, Canada.4Pediatric Critical Care Medicine, Departments of Pediatrics and Public Health Sciences, Penn State University College of Medicine, Hershey, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000978DOI Listing
January 2017

Acute Kidney Injury in Pediatric Severe Sepsis: An Independent Risk Factor for Death and New Disability.

Crit Care Med 2016 Dec;44(12):2241-2250

1Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.2Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.3Division of Critical Care Medicine and the Center for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.4Sections of Critical Care and Renal, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX.5Division of Pediatric Critical Care Medicine, Hospital Militar Central, Bogotá, Colombia.6Department of Pediatric Critical Care Medicine, Pablo Tobón Uribe Hospital, Medellín, Colombia.7Department of Pediatrics, State University of New York at Buffalo, Jacobs School of Medicine and Biomedical Sciences, and Division of Pediatric Critical Care, Women and Children's Hospital of Buffalo, Buffalo, NY.8Department of Pediatrics, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.9Paediatric Intensive Care Unit, Department of Child Health, King's College Hospital, London, United Kingdom.10Division of Pediatric Critical Care Medicine, Department of Pediatrics, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA.11Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA.12Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.13Division of Pediatric Critical Care Medicine, Penn State Hershey Children's Hospital, Penn State University College of Medicine, Hershey, PA.

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http://Insights.ovid.com/crossref?an=00003246-201612000-0001
Publisher Site
http://dx.doi.org/10.1097/CCM.0000000000002007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267552PMC
December 2016

2016 Update for the Rogers' Textbook of Pediatric Intensive Care: Recognition and Initial Management of Shock.

Pediatr Crit Care Med 2016 11;17(11):1073-1079

1Department of Anesthesia and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.2Department of Pediatrics, BC Children's Hospital and Sunny Hill Health Centre for Children, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PCC.0000000000000942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389123PMC
November 2016

Combining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids.

Crit Care Med 2016 10;44(10):e1000-3

1Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center and Cincinnati Children's Research Foundation, Cincinnati, OH.2Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.3Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH.4UCSF Benioff Children's Hospital Oakland, Oakland, CA.5Children's Hospital of Orange County, Orange, CA.6Children's Mercy Hospital, Kansas City, MO.7Penn State Hershey Children's Hospital, Hershey, PA.8Akron Children's Hospital, Akron, OH.9The Children's Hospital of Philadelphia, Philadelphia, PA.10Texas Children's Hospital and Baylor College of Medicine, Houston, TX.11Miami Children's Hospital, Miami, FL.12CS Mott Children's Hospital at the University of Michigan, Ann Arbor, MI.13Nationwide Children's Hospital, Columbus, OH.14Children's Hospital of Wisconsin, Milwaukee, WI.15Children's National Medical Center, Washington, DC.16Children's Hospital and Clinics of Minnesota, Minneapolis, MN.17Riley Hospital for Children, Indianapolis, IN.18Hackensack University Medical Center, Joseph M. Sanzari Children's Hospital, Hackensack, NJ.19Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.

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http://dx.doi.org/10.1097/CCM.0000000000001833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026540PMC
October 2016

Protocolized Treatment Is Associated With Decreased Organ Dysfunction in Pediatric Severe Sepsis.

Pediatr Crit Care Med 2016 09;17(9):817-22

1Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 2Division of Pediatric Emergency Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 3Department of Anesthesia and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA. 4Department of Anesthesia and Critical Care, Children's Hospital of Philadelphia, Philadelphia, PA. 5Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA. 6Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL. 7Division of Pediatric Emergency Medicine, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.

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http://dx.doi.org/10.1097/PCC.0000000000000858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008999PMC
September 2016

Hyperferritinemic Sepsis: An Opportunity for Earlier Diagnosis and Intervention?

Front Pediatr 2016 2;4:77. Epub 2016 Aug 2.

Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA , USA.

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http://dx.doi.org/10.3389/fped.2016.00077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969285PMC
August 2016

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia.

Cancer Discov 2016 06 13;6(6):664-79. Epub 2016 Apr 13.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Abramson Cancer Center, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Department of Pathology and Laboratory Medicine, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448406PMC
June 2016

Comparison of Pediatric Severe Sepsis Managed in U.S. and European ICUs.

Pediatr Crit Care Med 2016 06;17(6):522-30

1Division of Critical Care Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT. 2Division of Pediatric Critical Care, Departments of Pediatrics and Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA. 3Department of Critical Care and Bioethics, Great Ormond Street Hospital NHS Trust, London, United Kingdom. 4Department of Pediatrics, Royal Hospital for Children, Glasgow, Scotland. 5Intensive Care Department, Sydney Children's Hospital, Randwick, NSW, Australia. 6Department of Pediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia. 7Paediatric Intensive Care Unit, Division of Paediatric Critical Care, Department of Pediatrics, Lady Cilento Children's Hospital, Brisbane, QLD, Australia. 8Department of Pediatric Intensive Care, Hospital El Carmen de Maipu, Universidad Andres Bello, Santiago, Chile. 9Division of Critical Care Medicine, Department of Anesthesia and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 10Department of Political Science, Penn State University, University Park, PA. 11Division of Pediatric Critical Care Medicine, Department of Pediatrics, Penn State Hershey Children's Hospital, Penn State University College of Medicine, Hershey, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399539PMC
June 2016

Pediatric Severe Sepsis/Septic Shock Associated with Healthcare-Associated Infections.

Infect Control Hosp Epidemiol 2016 Apr 16;37(4):483-5. Epub 2015 Dec 16.

1Division of Infectious Diseases and Center for Pediatric Clinical Effectiveness,The Children's Hospital of Philadelphia,Philadelphia,Pennsylvania.

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http://dx.doi.org/10.1017/ice.2015.307DOI Listing
April 2016

Optimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection.

Pediatr Crit Care Med 2016 Apr;17(4):279-86

1Department of Anesthesia, Perioperative and Pain Medicine (Critical Care), Boston Children's Hospital, Boston, MA. 2Departments of Anaesthesia and Pediatrics, Harvard Medical School, Boston, MA. 3Department of Epidemiology, Boston University School of Public Health, Boston, MA. 4Tufts University School of Medicine, Boston, MA. 5Marshfield Clinic Research Foundation, Marshfield, WI. 6Department of Anesthesia and Critical Care, Children's Hospital of Philadelphia, Philadelphia, PA. 7Section of Critical Care Medicine, Department of Pediatrics, Texas Children's Hospital, Houston, TX. 8Pediatric Critical Care Division, Children's Hospital and Medical Center, Omaha, NE. 9Pediatric Critical Care Medicine, Maria Fareri Children's Hospital, Westchester, NY. 10Influenza Division, U.S. Centers for Disease Control and Prevention, Atlanta, GA. 11Battelle Memorial Institute, Atlanta, GA.

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http://dx.doi.org/10.1097/PCC.0000000000000661DOI Listing
April 2016

Invasive Mechanical Ventilation and Mortality in Pediatric Hematopoietic Stem Cell Transplantation: A Multicenter Study.

Pediatr Crit Care Med 2016 Apr;17(4):294-302

1Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN. 2Department of Pediatrics, Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, NJ. 3Department of Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI. 4Department of Anesthesia, Children's Hospital of Philadelphia University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 5Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN. 6Department of Pediatrics, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY. 7Department of Pediatrics, Dana-Farber Cancer Institute, Boston, MA. 8Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY. 9Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA. 10Department of Pediatrics, Duke Children's Hospital, Durham, NC. 11Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH. 12Department of Pediatrics, Pennsylvania State University College of Medicine, Penn State Hershey Children's Hospital, Hershey, PA. 13Department of Public Health, Pennsylvania State University College of Medicine, Penn State Hershey Children's Hospital, Hershey, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000673DOI Listing
April 2016

Comparison of Two Sepsis Recognition Methods in a Pediatric Emergency Department.

Acad Emerg Med 2015 Nov 16;22(11):1298-306. Epub 2015 Oct 16.

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1111/acem.12814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639443PMC
November 2015

Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study.

Crit Care 2015 Sep 16;19:325. Epub 2015 Sep 16.

Division of Critical Care Medicine, Department of Anesthesia and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/s13054-015-1055-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572676PMC
September 2015

Implementation of a pediatric critical care focused bedside ultrasound training program in a large academic PICU.

Pediatr Crit Care Med 2015 Mar;16(3):219-26

1Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA. 2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 3Department of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA. 4Department of Emergency Medicine, The Hospital of The University of Pennsylvania, Philadelphia, PA. 5Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA. 6Division of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000340DOI Listing
March 2015

Delayed antimicrobial therapy increases mortality and organ dysfunction duration in pediatric sepsis.

Crit Care Med 2014 Nov;42(11):2409-17

1Division of Critical Care Medicine, Department of Anesthesia and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Division of Emergency Medicine, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 3Division of Emergency Medicine, Department of Pediatrics, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL. 4The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA. 5Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 6Division of Pediatric Critical Care Medicine, Penn State Hershey Children's Hospital, Penn State University College of Medicine, Hershey, PA.

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http://dx.doi.org/10.1097/CCM.0000000000000509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213742PMC
November 2014

High-frequency percussive ventilation improves oxygenation and ventilation in pediatric patients with acute respiratory failure.

J Crit Care 2014 Apr 22;29(2):314.e1-7. Epub 2013 Nov 22.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2013.11.009DOI Listing
April 2014

Outcome of pediatric acute myeloid leukemia patients receiving intensive care in the United States.

Pediatr Crit Care Med 2014 Feb;15(2):112-20

1Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA. 2Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 3Department of Anesthesia and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA. 4Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 5Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, PA. 6Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Philadelphia, PA. 7Bristol-Myers Squibb, Hopewell, NJ. 8Division of Haematology/Oncology and Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada. 9Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 10Division of Pediatric Critical Care Medicine, Department of Pediatrics and Public Health Sciences, Penn State Hershey Milton S. Hershey Medical Center, Hershey, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407366PMC
February 2014

Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells.

Proc Natl Acad Sci U S A 2006 Mar 10;103(12):4592-7. Epub 2006 Mar 10.

Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Medical School, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.0508685103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450216PMC
March 2006