Julie A Schneider

Julie A Schneider

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Julie A Schneider

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Religious Orders Study and Rush Memory and Aging Project.

J Alzheimers Dis 2018 ;64(s1):S161-S189

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.3233/JAD-179939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380522PMC
June 2019

Neurofibrillary Tangles and Conversion to Mild Cognitive Impairment with Certain Antihypertensives.

J Alzheimers Dis 2019 Jun 6. Epub 2019 Jun 6.

Johns Hopkins University School of Medicine, Department of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.3233/JAD-190011DOI Listing
June 2019

Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease.

J Cell Sci 2019 Jun 14. Epub 2019 Jun 14.

Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA

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http://dx.doi.org/10.1242/jcs.229054DOI Listing
June 2019

Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults.

Neurobiol Aging 2019 05 31;77:104-111. Epub 2019 Jan 31.

Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Diagnostic Radiology, Rush University Medical Center, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486844PMC
May 2019

Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology.

Neuroepidemiology 2019 May 8:1-8. Epub 2019 May 8.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.

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http://dx.doi.org/10.1159/000500157DOI Listing
May 2019

Sex differences in mixed neuropathologies in community-dwelling older adults.

Brain Res 2019 May 22;1719:11-16. Epub 2019 May 22.

Rush Alzheimer's Disease Center, United States; Rush University Medical Center, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S00068993193028
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http://dx.doi.org/10.1016/j.brainres.2019.05.028DOI Listing
May 2019

Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies.

Neurology 2019 Apr 20;92(16):e1821-e1830. Epub 2019 Mar 20.

From the Rush Alzheimer's Disease Center (A.S.B., L.Y., R.S.W., S.E.L., S.N., L.L.B., J.A.S., D.A.B.), and Departments of Neurological Sciences (A.S.B., L.Y., R.S.W., S.E.L., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., L.L.B.), and Pathology (Neuropathology) (S.N., J.A.S.), Rush University Medical Center, Chicago, IL; Departments of Neurology, Molecular and Human Genetics, Neuroscience, and Program in Developmental Biology (J.M.S.), Baylor College of Medicine, Houston, TX; and Jan and Dan Duncan Neurological Research Institute (J.M.S.), Texas Children's Hospital, Houston.

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http://dx.doi.org/10.1212/WNL.0000000000007315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550497PMC
April 2019

Scam Awareness Related to Incident Alzheimer Dementia and Mild Cognitive Impairment: A Prospective Cohort Study.

Ann Intern Med 2019 Apr 16. Epub 2019 Apr 16.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois (P.A.B., L.Y., J.A.S., R.S.W., D.A.B.).

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http://dx.doi.org/10.7326/M18-2711DOI Listing
April 2019

Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.

JAMA Neurol 2019 Apr 22. Epub 2019 Apr 22.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamaneurol.2019.0834DOI Listing
April 2019

White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities.

Alzheimers Dement (N Y) 2019 9;5:107-117. Epub 2019 Apr 9.

Molecular & Clinical Sciences Research Institute, St George's University of London and Department of Neurology, St George's University Hospitals NHS Foundation Trust, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S23528737193000
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http://dx.doi.org/10.1016/j.trci.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461571PMC
April 2019

Education and cognitive reserve in old age.

Neurology 2019 Mar 6;92(10):e1041-e1050. Epub 2019 Feb 6.

From the Departments of Neurological Sciences (R.S.W., L.Y., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., M.L., P.A.B.), and Pathology (J.A.S.), Rush University Medical Center, Rush Alzheimer's Disease Center, Chicago, IL.

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http://dx.doi.org/10.1212/WNL.0000000000007036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442015PMC
March 2019

The time for multiple biomarkers in studies of cognitive aging and dementia is now.

Neurology 2019 Mar 27;92(12):551-552. Epub 2019 Feb 27.

From the Rush Alzheimer's Disease Center and Departments of Pathology and Neurological Sciences (J.A.S.), Rush University Medical Center, Chicago, IL; and Department of Neurology (A.V.), Massachusetts General Hospital Stroke Research Center, Harvard Medical School, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000007120DOI Listing
March 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gena Roschupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults.

Alzheimers Dement 2019 Feb 12;15(2):258-266. Epub 2018 Oct 12.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA; Department of Pathology, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2018.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368888PMC
February 2019

In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies.

Neurobiol Aging 2019 02 25;74:171-181. Epub 2018 Oct 25.

Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183037
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331233PMC
February 2019

Cognitive decline after elective and nonelective hospitalizations in older adults.

Neurology 2019 Feb 11;92(7):e690-e699. Epub 2019 Jan 11.

From the Rush Alzheimer's Disease Center (B.D.J., R.S.W., A.W.C., P.A.B., R.C.S., M.L., D.A.B., J.A.S.), Departments of Internal Medicine (B.D.J.), Neurological Sciences (R.S.W., A.W.C., M.L., D.A.B., J.A.S.), Behavioral Sciences (R.S.W., P.A.B.), Family Medicine (R.C.S.), and Pathology (J.A.S.), Rush University Medical Center, Chicago, IL; Center for Quality of Aging (E.W.E.), Vanderbilt Medical School, Nashville; Division of Allergy, Pulmonary, and Critical Care Medicine (E.W.E.), Vanderbilt University, Nashville; and Veterans Affairs Tennessee Valley Geriatric Research, Education, and Clinical Center (GRECC) (E.W.E.), Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.

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http://dx.doi.org/10.1212/WNL.0000000000006918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382369PMC
February 2019

Physical activity, common brain pathologies, and cognition in community-dwelling older adults.

Neurology 2019 Feb 16;92(8):e811-e822. Epub 2019 Jan 16.

From the Rush Alzheimer's Disease Center (A.S.B., L.Y., R.S.W., R.J.D., C.G., S.E.L., J.A.S., D.A.B.), and Departments of Neurological Sciences (A.S.B., L.Y., R.S.W., C.G., S.E.L., J.A.S., D.A.B.), Radiology (R.J.D.), Psychology (R.S.W.), and Pathology (Neuropathology) (J.A.S.), Rush University Medical Center, Chicago, IL; and Department of Neurology (A.L.), University of Toronto, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000006954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396972PMC
February 2019

Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.

Neurology 2019 Feb 23;92(8):e831-e840. Epub 2019 Jan 23.

From the Departments of Neurological Sciences (R.S.W., J.Y., L.Y., S.E.L., A.W.C., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., P.A.B.), and Pathology (J.A.S.), Rush University Medical Center, Rush Alzheimer's Disease Center, Chicago, IL.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396970PMC
February 2019

Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology.

Mol Psychiatry 2019 Feb 18. Epub 2019 Feb 18.

Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Vic, Australia.

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http://dx.doi.org/10.1038/s41380-019-0375-7DOI Listing
February 2019

Risk Aversion and Alzheimer Disease in Old Age.

Am J Geriatr Psychiatry 2019 Feb 21. Epub 2019 Feb 21.

Behavioral Sciences (RSW, PAB).

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http://dx.doi.org/10.1016/j.jagp.2019.02.011DOI Listing
February 2019

Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies.

Ann Neurol 2019 Jan 19;85(1):114-124. Epub 2018 Dec 19.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL.

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http://dx.doi.org/10.1002/ana.25380DOI Listing
January 2019

Spinal motor neurons and motor function in older adults.

J Neurol 2019 Jan 16;266(1):174-182. Epub 2018 Nov 16.

Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, Suite #1000; 1750 West Harrison Street, Chicago, IL, 60612, USA.

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http://link.springer.com/10.1007/s00415-018-9118-y
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http://dx.doi.org/10.1007/s00415-018-9118-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344292PMC
January 2019

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Alzheimers Dement 2019 01;15(1):158-167

Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Alzheimer's Disease Research Center, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.07.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338083PMC
January 2019

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.

Nat Commun 2019 01 24;10(1):409. Epub 2019 Jan 24.

Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, 630 West 168th Street, New York, NY, 10032, USA.

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http://dx.doi.org/10.1038/s41467-018-08279-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345810PMC
January 2019

Sex differences in Alzheimer's disease and common neuropathologies of aging.

Acta Neuropathol 2018 12 17;136(6):887-900. Epub 2018 Oct 17.

Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W Harrison, Suite 1000, Chicago, IL, USA.

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http://dx.doi.org/10.1007/s00401-018-1920-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279593PMC
December 2018

Watershed microinfarct pathology and cognition in older persons.

Neurobiol Aging 2018 10 30;70:10-17. Epub 2018 May 30.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Pathology (Neuropathology), Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378107PMC
October 2018

Fractal regulation and incident Alzheimer's disease in elderly individuals.

Alzheimers Dement 2018 09 4;14(9):1114-1125. Epub 2018 May 4.

Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA, USA; Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201319PMC
September 2018

Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults.

Neurobiol Aging 2018 09 23;69:177-184. Epub 2018 May 23.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424332PMC
September 2018

Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study.

Lancet Neurol 2018 09 6;17(9):773-781. Epub 2018 Aug 6.

The Broad Institute of MIT and Harvard, Cambridge, MA, USA; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30251-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154505PMC
September 2018

The Revised National Alzheimer's Coordinating Center's Neuropathology Form-Available Data and New Analyses.

J Neuropathol Exp Neurol 2018 Aug;77(8):717-726

Sanders-Brown Center on Aging, Division of Neuropathology, Department of Pathology, University of Kentucky, Lexington, Kentucky.

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http://dx.doi.org/10.1093/jnen/nly049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044344PMC
August 2018

Late-life blood pressure association with cerebrovascular and Alzheimer disease pathology.

Neurology 2018 Aug 11;91(6):e517-e525. Epub 2018 Jul 11.

From the Rush Alzheimer's Disease Center (Z.A., A.W.C., M.L., R.C.S., L.L.B., D.A.B., J.A.S.), and Departments of Neurological Sciences (Z.A., A.W.C., M.L., L.L.B., D.A.B., J.A.S.), Family Medicine (R.C.S.), Behavioral Sciences (L.L.B.), and Pathology (J.A.S.), Rush University Medical Center, Chicago, IL.

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http://dx.doi.org/10.1212/WNL.0000000000005951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105052PMC
August 2018

Spinal Lewy body pathology in older adults without an antemortem diagnosis of Parkinson's disease.

Brain Pathol 2018 07 27;28(4):560-568. Epub 2017 Oct 27.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL.

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http://dx.doi.org/10.1111/bpa.12560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874164PMC
July 2018

Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.

Mol Neurodegener 2018 07 24;13(1):38. Epub 2018 Jul 24.

Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, 630 West 168th Street, PH 19 - 302, New York, NY, 10032, USA.

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http://dx.doi.org/10.1186/s13024-018-0272-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057096PMC
July 2018

Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age.

Neurobiol Dis 2018 06 26;114:31-44. Epub 2018 Feb 26.

BC Mental Health and Addictions Research Institute, 938 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC, V6T 2A1, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09699961183003
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http://dx.doi.org/10.1016/j.nbd.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483375PMC
June 2018

Neurodegenerative disease and cognitive retest learning.

Neurobiol Aging 2018 06 29;66:122-130. Epub 2018 Mar 29.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383720PMC
June 2018

ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.

Neurology 2018 Jun 11;90(24):e2127-e2134. Epub 2018 May 11.

From Rush Alzheimer's Disease Center (S.O., A.S.B., L.Y., J.F., C.G., J.A.S., D.A.B.) and Departments of Neurological Sciences (A.S.B., L.Y., J.A.S., D.A.B.) and Pathology (J.F., J.A.S.), Rush University Medical Center, Chicago, IL; Shariati Hospital (S.O.), Tehran University of Medical Sciences, Iran; Department of Geriatrics (J.F.), University of Sao Paulo Medical School, Brazil; University Hospital (V.H.), University of Western Ontario, London, Canada; Broad Institute (P.L.D.J.), Cambridge, MA; Center for Translational & Systems Neuroimmunology (P.L.D.J.), Department of Neurology, Columbia University Medical Center, New York, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996834PMC
June 2018

Brain pathology is related to total daily physical activity in older adults.

Neurology 2018 May 25;90(21):e1911-e1919. Epub 2018 Apr 25.

From the Rush Alzheimer's Disease Center (A.S.B., R.J.D., L.Y., R.S.W., J.A.S., D.A.B.), Department of Neurological Sciences (A.S.B., L.Y., R.S.W., J.A.S., D.A.B.), Department of Radiology (R.J.D.), Department of Psychology (R.S.W.), and Department of Pathology (Neuropathology) (J.A.S.), Rush University Medical Center Chicago, IL; and Department of Neurology (A.L.), University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000005552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962918PMC
May 2018

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease.

Acta Neuropathol Commun 2018 05 1;6(1):33. Epub 2018 May 1.

Rush Alzheimer Disease Center, Rush University Medical Center, Suite 1000, 1750 W Harrison Street, Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1186/s40478-018-0531-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928580PMC
May 2018

Financial and Health Literacy Predict Incident Alzheimer's Disease Dementia and Pathology.

J Alzheimers Dis 2017 ;56(4):1485-1493

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.3233/JAD-161132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444544PMC
February 2018

Genetic influence of plasma homocysteine on Alzheimer's disease.

Neurobiol Aging 2018 02 13;62:243.e7-243.e14. Epub 2017 Oct 13.

Kimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Underserved Populations Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.09.033DOI Listing
February 2018

Vascular cognitive impairment.

Nat Rev Dis Primers 2018 Feb 15;4:18003. Epub 2018 Feb 15.

Alzheimer Center, Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, de Boelelaan 1118, 1081 HZ Amsterdam, Netherlands.

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February 2018

Age and the association of dementia-related pathology with trajectories of cognitive decline.

Neurobiol Aging 2018 01 5;61:138-145. Epub 2017 Sep 5.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.08.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721665PMC
January 2018

Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.

Alzheimers Dement 2017 Dec 15;13(12):1380-1388. Epub 2017 Jun 15.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723540PMC
December 2017

Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease.

Mov Disord 2017 Dec 30;32(12):1729-1737. Epub 2017 Oct 30.

Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/mds.27200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778902PMC
December 2017

Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology.

Alzheimer Dis Assoc Disord 2017 Jan-Mar;31(1):41-47

*Rush Alzheimer's Disease Center Departments of †Neurological Sciences ‡Pathology §Behavioral Sciences, Rush University Medical Center, Chicago, IL ∥Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins University, Baltimore, MD ¶Department of Neurology, Harvard Medical School, Interdisciplinary Brain Center, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1097/WAD.0000000000000172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321787PMC
November 2017

Role of APOE ε4 Allele and Incident Stroke on Cognitive Decline and Mortality.

Alzheimer Dis Assoc Disord 2016 Oct-Dec;30(4):318-323

Departments of *Internal Medicine, Rush Institute for Healthy Aging ‡Neurological Sciences §Behavioral Sciences †Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago IL ∥Department of Medicine, University of Minnesota, Minneapolis, MN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117953PMC
November 2017

The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice.

J Neurol Neurosurg Psychiatry 2017 11 26;88(11):982-994. Epub 2017 Aug 26.

Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.1136/jnnp-2016-314697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740546PMC
November 2017

Genetic epistasis regulates amyloid deposition in resilient aging.

Alzheimers Dement 2017 Oct 17;13(10):1107-1116. Epub 2017 Mar 17.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601013PMC
October 2017

Spinal Arteriolosclerosis Is Common in Older Adults and Associated With Parkinsonism.

Stroke 2017 10 20;48(10):2792-2798. Epub 2017 Sep 20.

From the Rush Alzheimer's Disease Center (A.S.B., S.E.L., S.N., A.K., J.A.S., D.A.B.), Department of Neurological Sciences (A.S.B., S.E.L., J.A.S., D.A.B.), and Department of Pathology (Neuropathology) (S.N., J.A.S.), Rush University Medical Center, Chicago, IL; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA (V.G.J.M.V.); and Harvard Medical School, Boston, MA (V.G.J.M.V.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659359PMC
October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Detection, risk factors, and functional consequences of cerebral microinfarcts.

Lancet Neurol 2017 09 14;16(9):730-740. Epub 2017 Jul 14.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30196-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861500PMC
September 2017

Impact of multiple pathologies on the threshold for clinically overt dementia.

Acta Neuropathol 2017 08 9;134(2):171-186. Epub 2017 May 9.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, USA.

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http://dx.doi.org/10.1007/s00401-017-1717-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663642PMC
August 2017

variants are associated with cerebral amyloid angiopathy.

Neurol Genet 2017 Aug 18;3(4):e176. Epub 2017 Jul 18.

Departments of Neurology and Psychiatry (H.-S.Y., C.C.W., H.-U.K., P.L.D.J.), Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences; Department of Neurology (H.-S.Y.), Center for Alzheimer Research and Treatment, Brigham and Women's Hospital; Harvard Medical School (H.-S.Y., H.-U.K.); Harvard T.H. Chan School of Public Health (L.B.C.), Boston; Program in Medical and Population Genetics (H.-S.Y., C.C.W., L.B.C., H.-U.K., P.L.D.J.), Broad Institute, Cambridge, MA; Rush Alzheimer's Disease Center (J.A.S., D.A.B.) and Department of Neurological Sciences (J.A.S., D.A.B.), Rush University Medical Center, Chicago, IL; and Department of Neurology (P.L.D.J.), Center for Translational & Systems Neuroimmunology, Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1212/NXG.0000000000000176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515600PMC
August 2017

The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.

PLoS One 2016 26;11(7):e0157452. Epub 2016 Jul 26.

Program in Translational Neuropsychiatric Genomics, Departments of Neurology & Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961370PMC
July 2017

Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.

Mol Neurodegener 2017 07 1;12(1):51. Epub 2017 Jul 1.

Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, 77 Avenue Louis Pasteur, NRB 168C, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s13024-017-0191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494142PMC
July 2017

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.

PLoS Med 2017 04 25;14(4):e1002287. Epub 2017 Apr 25.

Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404753PMC
April 2017

Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia.

Behav Brain Res 2017 03 3;322(Pt B):233-240. Epub 2016 Sep 3.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2016.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325779PMC
March 2017

TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD.

Neurology 2017 Feb 13;88(7):653-660. Epub 2017 Jan 13.

From the Rush Alzheimer's Disease Center (S.N., L.Y., R.S.W., E.-Y.C., D.A.B., J.A.S.) and Departments of Neurological Sciences (L.Y., R.S.W., D.A.B., J.A.S.), Behavioral Sciences (R.S.W.), and Pathology (Neuropathology) (S.N., J.A.S.), Rush University Medical Center, Chicago, IL.

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http://dx.doi.org/10.1212/WNL.0000000000003610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317379PMC
February 2017

The Relationship of Cerebral Vessel Pathology to Brain Microinfarcts.

Brain Pathol 2017 01 14;27(1):77-85. Epub 2016 Apr 14.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL.

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http://dx.doi.org/10.1111/bpa.12365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974145PMC
January 2017

TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.

Brain 2016 11;139(11):2983-2993

Rush Alzheimer's Disease Center, Rush University Medical Center, Department of Neurological Sciences, 600 s. Paulina Street, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1093/brain/aww224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091047PMC
November 2016

Late-Life Vascular Risk Factors and Alzheimer Disease Neuropathology in Individuals with Normal Cognition.

J Neuropathol Exp Neurol 2016 Oct 11;75(10):955-962. Epub 2016 Aug 11.

From the National Alzheimer's Coordinating Center, University of Washington, Seattle, Washington, USA (LMB, XHZ, WAK), Boston University Alzheimer's Disease and CTE Center (MLA, ACM, RAS), Department of Neurology, Boston University School of Medicine, Boston, MA, USA (MLA, ACM, RAS), Department of Neurology, University of California, San Francisco, CA, USA (LRG), VA Boston Healthcare System, U.S. Department of Veteran Affairs, Boston, MA, USA (ACM), Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA (ACM), Department of Veterans Affairs Medical Center, Bedford, MA, USA (ACM), Department of Neurosurgery and Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA (RAS), Department of Psychological Sciences, Kent State University, Kent, OH, USA (JG), Departments of Pathology and Neurological Science, Rush Alzheimer's Disease Center, Rush University, Chicago, IL, USA (JAS) and University of Southern California, Los Angeles, CA, USA (HC).

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http://dx.doi.org/10.1093/jnen/nlw072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029440PMC
October 2016

White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age.

Ann Clin Transl Neurol 2016 10 1;3(10):791-800. Epub 2016 Sep 1.

Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois; Department of Neurological Sciences Rush University Medical Center Chicago Illinois.

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http://dx.doi.org/10.1002/acn3.343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048389PMC
October 2016

Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.

Alzheimers Dement 2016 09 24;12(9):942-951. Epub 2016 Mar 24.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2016.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014706PMC
September 2016

Postmortem MRI: a novel window into the neurobiology of late life cognitive decline.

Neurobiol Aging 2016 09 6;45:169-177. Epub 2016 Jun 6.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003419PMC
September 2016

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.

Alzheimers Dement 2016 08 23;12(8):882-9. Epub 2016 Jan 23.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Rush University Medical Center, Department of Neurological Sciences, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958598PMC
August 2016

Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study.

Lancet Neurol 2016 08 14;15(9):934-943. Epub 2016 Jun 14.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA; Department of Pathology, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/S1474-4422(16)30029-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969105PMC
August 2016

Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.

Neurology 2016 Aug 1;87(5):489-96. Epub 2016 Jul 1.

From the Department of Geriatrics (J.M.F.), University of Sao Paulo Medical School, Brazil; Department of Pathology (J.M.F., J.A.S.), Rush Alzheimer's Disease Center (J.M.F., L.Y., A.S.B., J.A.S., D.A.B.), and Department of Neurological Sciences (L.Y., A.S.B., J.A.S., D.A.B.), Rush University Medical Center, Chicago, IL; Program in Translational NeuroPsychiatric Genomics (P.L.D.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston; Harvard Medical School (P.L.D.), Boston; and Program in Medical and Population Genetics (P.L.D.), Broad Institute, Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000002909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970661PMC
August 2016

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.

Neurol Genet 2016 Aug 26;2(4):e90. Epub 2016 Jul 26.

Ann Romney Center for Neurologic Diseases (G.C., C.C.W., P.A.W., M.C., J.M.R., L.R.G., N.E.C., K.J.R., L.B.C., P.L.D.J., E.M.B.), Program in Translational NeuroPsychiatric Genomics (G.C., C.C.W., P.A.W., M.C., J.M.R., L.R.G., N.E.C., K.J.R., L.B.C., P.L.D.J., E.M.B.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Center for Alzheimer's Research and Treatment (K.A.J., R.A.S.), Department of Neurology, Brigham and Women's Hospital, Boston, MA; Program in Medical and Population Genetics (G.C., C.C.W., P.A.W., M.C., J.M.R., L.R.G., N.E.C., K.J.R., L.B.C., P.L.D.J., E.M.B.), Broad Institute, Cambridge, MA; Harvard Medical School (G.C., J.M.R., K.J.R., K.A.J., L.B.C., R.A.S., P.L.D.J., E.M.B.), Boston, MA; Department of Neurology (K.A.J., R.A.S.), Massachusetts General Hospital, Boston; and Rush Alzheimer's Disease Center (J.A.S., D.A.B.), Rush University Medical Center, Chicago, IL.

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http://dx.doi.org/10.1212/NXG.0000000000000090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962525PMC
August 2016

The cerebral cortex in cerebral amyloid angiopathy.

Lancet Neurol 2016 07;15(8):778-779

Department of Pathology (Neuropathology), Rush Alzheimer's Disease Center, Rush University Medical Center, Armour Academic Center, Chicago, IL 60612, USA; Department of Neurological Sciences, Rush Alzheimer's Disease Center, Rush University Medical Center, Armour Academic Center, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)30100-4DOI Listing
July 2016

Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.

Neurology 2016 Feb 27;86(8):735-41. Epub 2016 Jan 27.

From the Rush Alzheimer's Disease Center (A.S.B., L.Y., P.A.B., J.A.S., D.A.B.), Neurological Science (A.S.B., L.Y., J.A.S., D.A.B.), Behavioral Sciences (P.A.B.), Pathology (Neuropathology) (J.A.S.), Rush University Medical Center, Chicago, IL; Program in Translational NeuroPsychiatric Genomics (P.L.D.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston; Harvard Medical School (P.L.D.), Boston; and Program in Medical and Population Genetics, Broad Institute (P.L.D.), Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000002387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763800PMC
February 2016