Publications by authors named "Julian Huppert"

25Publications

What do the British public think of inequality in health, wealth, and power?

Soc Sci Med 2019 02 12;222:198-206. Epub 2019 Jan 12.

International Economic History, Faculty of History, University of Cambridge, UK.

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http://dx.doi.org/10.1016/j.socscimed.2019.01.006DOI Listing
February 2019

Corrigendum: Identification of multiple genomic DNA sequences which form i-motif structures at neutral pH.

Nucleic Acids Res 2017 12;45(22):13095-13096

School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.

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http://dx.doi.org/10.1093/nar/gkx1178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728391PMC
December 2017

Identification of multiple genomic DNA sequences which form i-motif structures at neutral pH.

Nucleic Acids Res 2017 04;45(6):2951-2959

School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.

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http://dx.doi.org/10.1093/nar/gkx090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605235PMC
April 2017

Distance-dependent duplex DNA destabilization proximal to G-quadruplex/i-motif sequences.

Nucleic Acids Res 2013 Aug 14;41(15):7453-61. Epub 2013 Jun 14.

Cavendish Laboratory, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK, Institute of Inorganic Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland and University of Nice-Sophia Antipolis, UMR 7272 CNRS, Institut de 40 Chimie de Nice, 28 Avenue Valrose, 06108 Nice, France.

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http://dx.doi.org/10.1093/nar/gkt476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753619PMC
August 2013

Stability and structure of long intramolecular G-quadruplexes.

Biochemistry 2012 Apr 5;51(15):3154-61. Epub 2012 Apr 5.

Cavendish Laboratory, University of Cambridge, Cambridge CB3 OHE, UK.

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http://dx.doi.org/10.1021/bi201750gDOI Listing
April 2012

A toolbox for predicting g-quadruplex formation and stability.

J Nucleic Acids 2010 Jun 8;2010. Epub 2010 Jun 8.

Cavendish Laboratory, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK.

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http://dx.doi.org/10.4061/2010/564946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915886PMC
June 2010

Structure, location and interactions of G-quadruplexes.

Authors:
Julian L Huppert

FEBS J 2010 Sep 29;277(17):3452-8. Epub 2010 Jul 29.

Cavendish Laboratory, University of Cambridge, UK.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07758.xDOI Listing
September 2010

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression.

Nucleic Acids Res 2009 Nov 10;37(20):6716-22. Epub 2009 Sep 10.

Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.

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http://dx.doi.org/10.1093/nar/gkp740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777450PMC
November 2009

Direct visualization of G-quadruplexes in DNA using atomic force microscopy.

Nucleic Acids Res 2009 Oct 20;37(18):6269-75. Epub 2009 Aug 20.

Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, UK.

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http://dx.doi.org/10.1093/nar/gkp679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764456PMC
October 2009

Interfacing systems biology and synthetic biology.

Genome Biol 2009 26;10(6):309. Epub 2009 Jun 26.

Centre for Integrated Systems Biology of Ageing and Nutrition (CISBAN) and School of Computing Science, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2009-10-6-309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718492PMC
September 2009

Stable G-quadruplexes are found outside nucleosome-bound regions.

Mol Biosyst 2009 Dec 14;5(12):1713-9. Epub 2009 May 14.

Cavendish Laboratory, University of Cambridge, JJ Thomson Ave, Cambridge, UK.

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http://xlink.rsc.org/?DOI=b905848f
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http://dx.doi.org/10.1039/b905848fDOI Listing
December 2009

Meeting report: second international meeting on quadruplex DNA.

Biochimie 2009 Sep 23;91(9):1059-65. Epub 2009 Jun 23.

Dept of Medical and Molecular Genetics, Indiana University Melvin and Bren Simon Cancer Center, Indiana University Center for Regenerative Biology and Medicine, Indiana University School of Medicine, IB 242 Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1016/j.biochi.2009.06.011DOI Listing
September 2009

Function and targeting of G-quadruplexes.

Curr Opin Mol Ther 2009 Apr;11(2):146-55

University of Cambridge, Cavendish Laboratory, J J Thomson Avenue, Cambridge, UK.

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April 2009

G-quadruplexes: the beginning and end of UTRs.

Nucleic Acids Res 2008 Nov 2;36(19):6260-8. Epub 2008 Oct 2.

Cavendish Laboratory, University of Cambridge, JJ Thompson Ave, Cambridge, UK.

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http://dx.doi.org/10.1093/nar/gkn511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577360PMC
November 2008

Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes.

Chem Soc Rev 2008 Jul 6;37(7):1375-84. Epub 2008 May 6.

Cavendish Laboratory, University of Cambridge, JJ Thomson Ave, Cambridge, UKCB3 0HE.

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http://xlink.rsc.org/?DOI=b702491f
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http://dx.doi.org/10.1039/b702491fDOI Listing
July 2008

Thermodynamic prediction of RNA-DNA duplex-forming regions in the human genome.

Authors:
Julian L Huppert

Mol Biosyst 2008 Jun 30;4(6):686-91. Epub 2008 Apr 30.

Cavendish Laboratory, University of Cambridge, JJ Thomson Avenue, Cambridge, UK.

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http://dx.doi.org/10.1039/b800354hDOI Listing
June 2008

Four-stranded DNA: cancer, gene regulation and drug development.

Philos Trans A Math Phys Eng Sci 2007 Dec;365(1861):2969-84

Cavendish Laboratory, Department of Physics, University of Cambridge, J. J. Thomson Avenue, Cambridge CB3 0HE, UK.

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http://dx.doi.org/10.1098/rsta.2007.0011DOI Listing
December 2007

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:
Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong
June 2007

An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.

Nat Chem Biol 2007 Apr 25;3(4):218-21. Epub 2007 Feb 25.

University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, UK.

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http://dx.doi.org/10.1038/nchembio864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206252PMC
April 2007

G-quadruplexes in promoters throughout the human genome.

Nucleic Acids Res 2007 14;35(2):406-13. Epub 2006 Dec 14.

Cambridge University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.

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http://dx.doi.org/10.1093/nar/gkl1057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802602PMC
March 2007

Putative DNA quadruplex formation within the human c-kit oncogene.

J Am Chem Soc 2005 Aug;127(30):10584-9

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.

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http://dx.doi.org/10.1021/ja050823uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195896PMC
August 2005

Prevalence of quadruplexes in the human genome.

Nucleic Acids Res 2005 24;33(9):2908-16. Epub 2005 May 24.

University Chemical Laboratory, University of Cambridge Lensfield Road, Cambridge CB2 1EW, UK.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gki609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140081PMC
June 2005

Loop-length-dependent folding of G-quadruplexes.

J Am Chem Soc 2004 Dec;126(50):16405-15

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.

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https://pubs.acs.org/doi/10.1021/ja045154j
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http://dx.doi.org/10.1021/ja045154jDOI Listing
December 2004