Dr Julian C Shillcock, PhD - Blue Brain Project, Ecole Polytechnique Fédérale de Lausane - Senior Scientific Collaborator

Dr Julian C Shillcock

PhD

Blue Brain Project, Ecole Polytechnique Fédérale de Lausane

Senior Scientific Collaborator

Lausanne, Vaud | Switzerland

Main Specialties: Biology

Additional Specialties: Biophysics


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Dr Julian C Shillcock, PhD - Blue Brain Project, Ecole Polytechnique Fédérale de Lausane - Senior Scientific Collaborator

Dr Julian C Shillcock

PhD

Introduction

Julian received his PhD at Simon Fraser University in Canada for work on Monte Carlo simulations of liquid crystal phase transitions and the elastic properties of fluid and polymerized membranes.

He was a Group Leader at the Max Planck Institute of Colloids and Interfaces, Germany for five years applying coarse-grained simulation techniques - principally Dissipative Particle Dynamics (DPD) and Brownian Dynamics - to equilibrium and dynamic properties of fluid lipid membranes. A major target of this research was to reveal the molecular rearrangements that occur during vesicle fusion. During this time, he developed a commercially-available, parallel DPD code that is being used by several universities.

He was an Associate Professor at MEMPHYS in the Department of Physics and Chemistry, University of Southern Denmark. He has also worked in industry, designing and writing software for communication satellite simulations (British Aerospace, 1986-1990), and fluid simulation software (Accelrys, Inc., 1998-1999).

He joined the Blue Brain Project in 2011, and uses mesoscale simulation techniques, together with theoretical analysis and collaborations with experimentalists, to study the dynamics of cellular processes. Current projects include simulating the formation of the post-synaptic density in dendritic spines, and measuring its properties in vitro using super resolution microscopic techniques; and developing theoretical models of the supramolecular organisation of synapses.

Primary Affiliation: Blue Brain Project, Ecole Polytechnique Fédérale de Lausane - Lausanne, Vaud , Switzerland

Specialties:

Additional Specialties:

Research Interests:


View Dr Julian C Shillcock’s Resume / CV

Education

Jul 1995
Simon Fraser University
PhD
May 1984
Simon Fraser University
MSc
Jun 1982
Kings College London
B.Sc (Hons)

Publications

9Publications

125Reads

1Profile Views

83PubMed Central Citations

Clustering on Membranes: Fluctuations and More.

Trends Cell Biol 2018 05 1;28(5):405-415. Epub 2018 Mar 1.

Blue Brain Project, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2018.01.009DOI Listing
May 2018
21 Reads
4 Citations
12.010 Impact Factor

Mechanism of Shiga Toxin Clustering on Membranes.

ACS Nano 2017 01 16;11(1):314-324. Epub 2016 Dec 16.

Ecole polytechnique fédérale de Lausanne (EPFL) , 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/acsnano.6b05706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348102PMC
January 2017
32 Reads
10 Citations
12.881 Impact Factor

Reconstructing the brain: from image stacks to neuron synthesis.

Brain Inform 2016 Dec 24;3(4):205-209. Epub 2016 Feb 24.

Allen Institute for Brain Science, Seattle, WA, 98109, USA.

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http://dx.doi.org/10.1007/s40708-016-0041-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106405PMC
December 2016
15 Reads
1 Citation

Vesicles and vesicle fusion: coarse-grained simulations.

Methods Mol Biol 2013 ;924:659-97

École polytechnique fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/978-1-62703-017-5_26DOI Listing
February 2013
10 Reads
4 Citations

Spontaneous vesicle self-assembly: a mesoscopic view of membrane dynamics.

Langmuir 2012 Jan 8;28(1):541-7. Epub 2011 Dec 8.

MEMPHYS, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark.

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http://dx.doi.org/10.1021/la2033803DOI Listing
January 2012
10 Reads
2 Citations
4.460 Impact Factor

Insight or illusion? Seeing inside the cell with mesoscopic simulations.

HFSP J 2008 Feb 30;2(1):1-6. Epub 2008 Jan 30.

MEMPHYS - Centre for Biomembrane Physics, University of Southern Denmark, Campusvej 55 5230 Odense M, Denmark.

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http://dx.doi.org/10.2976/1.2833599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640998PMC
February 2008
6 Reads
8 Citations

The computational route from bilayer membranes to vesicle fusion.

J Phys Condens Matter 2006 Jul 28;18(28):S1191-219. Epub 2006 Jun 28.

Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germanyhttp://www.mpikg.mpg.de/th.

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http://dx.doi.org/10.1088/0953-8984/18/28/S06DOI Listing
July 2006
8 Reads
6 Citations
2.350 Impact Factor

Tension-induced fusion of bilayer membranes and vesicles.

Nat Mater 2005 Mar 13;4(3):225-8. Epub 2005 Feb 13.

Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germany.

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http://dx.doi.org/10.1038/nmat1333DOI Listing
March 2005
7 Reads
48 Citations
36.425 Impact Factor