Publications by authors named "Julia Kowal"

30Publications

Structure of the human lipid exporter ABCB4 in a lipid environment.

Nat Struct Mol Biol 2020 01 23;27(1):62-70. Epub 2019 Dec 23.

Department of Biology, ETH Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1038/s41594-019-0354-3DOI Listing
January 2020

Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.

Science 2019 12;366(6471):1372-1375

Institute of Molecular Biology and Biophysics, Eidgenössische Technische Hochschule (ETH), CH-8093 Zürich, Switzerland.

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http://dx.doi.org/10.1126/science.aaz3505DOI Listing
December 2019

Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.

Nat Commun 2019 04 12;10(1):1722. Epub 2019 Apr 12.

Center for Cellular Imaging and NanoAnalytics, Biozentrum, University of Basel, Mattenstrasse 26, CH-4058, Basel, Switzerland.

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http://dx.doi.org/10.1038/s41467-019-09661-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461647PMC
April 2019

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.

Science 2019 02;363(6428):753-756

Institute of Molecular Biology and Biophysics, ETH Zürich, Otto-Stern-Weg 5, 8093 Zürich, Switzerland.

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http://dx.doi.org/10.1126/science.aav7102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800160PMC
February 2019

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.

Nature 2018 11 7;563(7731):426-430. Epub 2018 Nov 7.

Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zurich, Switzerland.

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http://www.nature.com/articles/s41586-018-0680-3
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http://dx.doi.org/10.1038/s41586-018-0680-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379061PMC
November 2018

Image processing techniques for high-resolution structure determination from badly ordered 2D crystals.

J Struct Biol 2018 08 22;203(2):120-134. Epub 2018 Apr 22.

Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, CH-4058 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2018.03.013DOI Listing
August 2018

Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.

Nat Struct Mol Biol 2018 04 2;25(4):333-340. Epub 2018 Apr 2.

Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41594-018-0049-1DOI Listing
April 2018

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.

Proc Natl Acad Sci U S A 2018 02 13;115(9):E1973-E1982. Epub 2018 Feb 13.

Institute of Molecular Biology and Biophysics, ETH Zürich, 8093 Zürich, Switzerland;

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http://dx.doi.org/10.1073/pnas.1717044115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834697PMC
February 2018

Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation.

Science 2018 02 4;359(6375):545-550. Epub 2018 Jan 4.

Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zurich, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1126/science.aar5140DOI Listing
February 2018

High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.

Structure 2018 01 14;26(1):20-27.e3. Epub 2017 Dec 14.

Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, WRO-1058, Mattenstrasse 26, 4058 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.str.2017.11.012DOI Listing
January 2018

Lipid Internal Dynamics Probed in Nanodiscs.

Chemphyschem 2017 Oct 30;18(19):2651-2657. Epub 2017 Jun 30.

CBMN, CNRS., University of Bordeaux, IECB, All. Geoffroy Saint-Hilaire, 34600, Pessac, France.

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http://dx.doi.org/10.1002/cphc.201700450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697661PMC
October 2017

Structure of the human multidrug transporter ABCG2.

Nature 2017 06 29;546(7659):504-509. Epub 2017 May 29.

Institute of Molecular Biology and Biophysics, ETH Zürich, Otto-Stern-Weg 5, 8093 Zürich, Switzerland.

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http://www.nature.com/doifinder/10.1038/nature22345
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http://dx.doi.org/10.1038/nature22345DOI Listing
June 2017

Robust image alignment for cryogenic transmission electron microscopy.

J Struct Biol 2017 03 27;197(3):279-293. Epub 2016 Dec 27.

Center for Cellular Imaging and NanoAnalytics, Biozentrum, Universität Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.jsb.2016.12.006DOI Listing
March 2017

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I.

Nat Struct Mol Biol 2017 02 26;24(2):187-193. Epub 2016 Dec 26.

Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/nsmb.3345DOI Listing
February 2017

Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels.

Nat Commun 2016 09 20;7:12789. Epub 2016 Sep 20.

INSERM U1006, Aix-Marseille Université, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille 13009, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034309PMC
http://dx.doi.org/10.1038/ncomms12789DOI Listing
September 2016

Preparation and Characterization of Stable α-Synuclein Lipoprotein Particles.

J Biol Chem 2016 Apr 4;291(16):8516-27. Epub 2016 Feb 4.

From the Laboratory of Physical Chemistry and Structural Biology Laboratory, The Salk Institute, La Jolla, California 92037 and

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http://dx.doi.org/10.1074/jbc.M115.707968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861424PMC
April 2016

Functional surface engineering by nucleotide-modulated potassium channel insertion into polymer membranes attached to solid supports.

Biomaterials 2014 Aug 6;35(26):7286-94. Epub 2014 Jun 6.

Chemistry Department, University of Basel, Klingelbergstrasse 80, 4056 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.05.043DOI Listing
August 2014

2dx_automator: implementation of a semiautomatic high-throughput high-resolution cryo-electron crystallography pipeline.

J Struct Biol 2014 May 28;186(2):302-7. Epub 2014 Mar 28.

Center for Cellular Imaging and NanoAnalytics, Biozentrum, University of Basel, CH-4058 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2014.03.016DOI Listing
May 2014

Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.

Nat Commun 2014 ;5:3106

Center for Cellular Imaging and NanoAnalytics, Biozentrum, University of Basel, Mattenstrasse 26, CH-4058 Basel, Switzerland.

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http://dx.doi.org/10.1038/ncomms4106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086158PMC
October 2015

Single particle 3D reconstruction for 2D crystal images of membrane proteins.

J Struct Biol 2014 Mar 29;185(3):267-77. Epub 2013 Dec 29.

Center for Cellular Imaging and NanoAnalytics, Biozentrum, University Basel, 4058 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2013.12.011DOI Listing
March 2014

Children must be protected from the tobacco industry's marketing tactics.

Authors:
Nicholas Hopkinson Colin Wallis Bernard Higgins Stephen Gaduzo Rebecca Sherrington Sarah Keilty Myra Stern John Britton Andrew Bush John Moxham Karl Sylvester Valerie Griffiths Tim Sutherland Iain Crossingham Raghu Raju Charlotte Spencer Shahideh Safavi Paul Deegan John Seymour Katherine Hickman John Hughes Jason Wieboldt Fizah Shaheen Clive Peedell Nesta Mackenzie David Nicholl Caroline Jolley Gillian Crooks Gillian Crooks Claire Dow Pete Deveson Oliver Bintcliffe Barry Gray Sanjay Kumar Sarah Haney Marianne Docherty Angela Thomas Felix Chua Akshay Dwarakanath Geoffrey Summers Keith Prowse Stephen Lytton Yee Ean Ong Jennifer Graves Tushar Banerjee Peter English Andrew Leonard Martin Brunet Nauman Chaudhry Robert Ian Ketchell Natalie Cummings Jenny Lebus Charles Sharp Chris Meadows Amelie Harle Tara Stewart Diane Parry Suzanne Templeton-Wright John Moore-Gillon James Stratford- Martin Sarvesh Saini Simon Matusiewicz Simon Merritt Lee Dowson Karnan Satkunam Luke Hodgson Eui-Sik Suh Hannah Durrington Emma Browne Nicola Walters Joerg Steier Simon Barry Mark Griffiths Nicholas Hart Marko Nikolic Matthew Berry Ajit Thomas Joy Miller Diarmuid McNicholl Paul Marsden Geoffrey Warwick Laura Barr David Adeboyeku Mohd Shahrin Mohd Noh Paul Griffiths Lisa Davies Jennifer Quint Rebecca Lyall Jonathan Shribman Andrea Collins Jon Goldman Susannah Bloch Alison Gill William Man Anne Christopher Razouqi Yasso Ashwin Rajhan Dinesh Shrikrishna Caroline Moore Gareth Absalom Richard Booton Robert William Fowler Carolyn Mackinlay Elizabeth Sapey Sara Lock Paul Walker Akhilesh Jha Imran Satia Bethia Bradley Naveed Mustfa Raana Haqqee Matt Thomas Anant Patel Anthony Redington Anilkumar Pillai Niall Keaney Stephen Fowler Lesley Lowe Amanda Brennan Douglas Morrison Clare Murray Jenny Hankinson P Dutta Matthew Maddocks Martino Pengo Katrina Curtis Gerrard Rafferty John Hutchinson Ruth Whitfield Steve Turner Ronan Breen Shams-un-nisa Naveed Chris Goode Georgina Esterbrook Liju Ahmed Woolf Walker David Ford Gary Connett Philip Davidson Will Elston Andrew Stanton David Morgan James Myerson David Maxwell Ann Harrris Sonia Parmar Catherine Houghton Robert Winter Zudin Puthucheary Fiona Thomson Sharon Sturney John Harvey Patricia L Haslam Irem Patel David Jennings Simon Range Brendan Mallia-Milanes Anne Collett Paul Tate Richard Russell Johanna Feary Ronan O'Driscoll James Eaden Jonathan Round Emma Sharkey Mary Montgomery Sophie Vaughan Kate Scheele Anna Lithgow Samuel Partridge Richard Chavasse Louise Restrick Sanjay Agrawal Said Abdallah Amruta Lacy-Colson Nick Adams Sally Mitchell Helmy Haja Mydin Ann Ward Sarah Denniston Mark Steel Dipansu Ghosh Stephen Connellan Lucy Rigge Ruth Williams Alison Grove Sadia Anwar Lee Dobson Harold Hosker David Stableforth Neil Greening Tim Howell Georgina Casswell Sarah Davies Georgia Tunnicliffe Philip Mitchelmore Elpida Phitidis Louise Robinson Keith Prowse Mona Bafadhel Grace Robinson Alison Boland Marc Lipman Stephen Bourke Sundeep Kaul Calvin Cowie Ian Forrest Elizabeth Starren Hannah Burke John Furness Angshu Bhowmik Caroline Everett Douglas Seaton Steve Holmes Simon Doe Samuel Parker Annika Graham Ian Paterson Usman Maqsood Chandra Ohri Peter Iles Samuel Kemp Ahsan Iftikhar Chris Carlin Tim Fletcher Peter Emerson Victoria Beasley Michelle Ramsay Robert Buttery Sarah Mungall Stephen Crooks John Ridyard David Ross Alison Guadagno Emma Holden Ian Coutts Kathy Cullen Sally O'Connor Jack Barker Katherine Sloper John Watson Peter Smith Paul Anderson Louise Brown Cyril Nyman Heather Milburn Amelia Clive Matthew Serlin Charlotte Bolton Jonathan Fuld Helen Powell Mark Dayer Ian Woolhouse Adamantia Georgiadi Helen Leonard James Dodd Ian Campbell Gary Ruiz Andrew Zurek James Y Paton Adam Malin Fraser Wood Gareth Hynes David Connell David Spencer Sarah Brown David Smith David Cooper Cecilia O'Kane Alex Hicks Ben Creagh-Brown James Lordan Annabel Nickol Robert Primhak Louise Fleming Duncan Powrie Joanna Brown Zaid Zoumot Sarah Elkin Joanna Szram Anthony Scaffardi Robert Marshall Ian Macdonald Darren Lightbody Ray Farmer Iain Wheatley Paul Radnan Ian Lane Andrew Booth Sean Tilbrook Toby Capstick Lee Hewitt Martin McHugh Christopher Nelson Patrick Wilson Vijay Padmanaban John White John Davison Una O'Callaghan Matthew Hodson John Edwards Colin Campbell Simon Ward Edwina Wooler Elizabeth Ringrose Diana Bridges Matthew Hodson John Edwards Colin Campbell Simon Ward Edwina Wooler Elizabeth Ringrose Diana Bridges Rosalind Backham Kim Randall Tracey Mathieson Alex Long Marilyn Parkes Sarah Clarke Bev Allen Carol Connelly Georgia Forster Jacky Hoadley Katharine Martin Kate Barnham Katie Khan Maureen Munday Catherine Edwards Doreen O'Hara Sally Turner Sue Pieri-Davies Kate Ford Tracey Daniels Joanne Wright Rebecca Towns Karen Fern Jane Butcher Karen Burgin Barbara Winter Debbie Freeman Sandra Olive Linda Gray Kathy Pye Debbie Roots Nicola Cox Carol-Anne Davies Jacquelyne Wicker Kay Hilton Jananee Lloyd Vicky MacBean Marion Wood Julia Kowal Janis Downs Helen Ryan Fran Guyatt Debby Nicoll Elizabeth Lyons Divya Narasimhan Anne Rodman Sandy Walmsley Alison Newey Maria Buxton Maria Dewar Angela Cooper Jacqui Reilly Julie Lloyd Alison Bennett Macmillan Debbie Roots Amy Olley Nia Voase Sarah Martin Iona McCarvill Anne Christensen Rowan Agate Karen Heslop Amber Timlett Karen Hailes Claire Davey Barbara Pawulska Amber Lane Shona Ioakim Alexandra Hough Jo Treharne Helen Jones Alice Winter-Burke Lauren Miller Bronwen Connolly Lyn Bingham Una Fraser Julia Bott Carol Johnston Alison Graham Denise Curry Helen Sumner Carol Ann Costello Charlotte Bartoszewicz Ros Badman Kathryn Williamson Amy Taylor Helen Purcell Emma Barnett Alanna Molloy Laura Crawfurd Nicola Collins Valerie Monaghan Misbah Mir Victoria Lord Janet Stocks Adrian Edwards Trish Greenhalgh Warren Lenney Martin McKee Danny McAuley Azeem Majeed John Cookson Emma Baker Sam Janes Wisia Wedzicha David Lomas Dean Brian Harrison Tony Davison Peter Calverley Robert Wilson Robert Stockley Jon Ayres John Gibson John Simpson Sherwood Burge John Warner Warren Lenney Neil Thomson Peter Davies Ashley Woodcock Mark Woodhead Stephen Spiro Lawrence Ormerod Graham Bothamley Martyn Partridge Michael Shields Hugh Montgomery Anita Simonds Peter Barnes Stephen Durham Sarah Malone Gilda Arabnia Sharon Olivier Karen Gardiner Sheila Edwards

BMJ 2013 Dec 9;347:f7358. Epub 2013 Dec 9.

British Thoracic Society Chronic Obstructive Pulmonary Disease Specialist Advisory Group, National Heart and Lung Institute, Imperial College, London SW3 6NP, UK.

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http://dx.doi.org/10.1136/bmj.f7358DOI Listing
December 2013

Structure of the dodecameric Yersinia enterocolitica secretin YscC and its trypsin-resistant core.

Structure 2013 Dec 24;21(12):2152-61. Epub 2013 Oct 24.

Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University Basel, Mattenstrasse 26, 4058 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.str.2013.09.012DOI Listing
December 2013

Reconstitution of water channel function and 2D-crystallization of human aquaporin 8.

Biochim Biophys Acta 2012 Mar 13;1818(3):839-50. Epub 2011 Dec 13.

Department of Biochemistry and Structural Biology, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/j.bbamem.2011.12.006DOI Listing
March 2012

The 2DX robot: a membrane protein 2D crystallization Swiss Army knife.

J Struct Biol 2010 Mar 4;169(3):370-8. Epub 2009 Dec 4.

Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.jsb.2009.12.001DOI Listing
March 2010