Juli Feigon

Juli Feigon

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Juli Feigon

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Structural Biology of Telomerase.

Cold Spring Harb Perspect Biol 2019 Dec 2;11(12). Epub 2019 Dec 2.

Department of Chemistry and Biochemistry, University of California Los Angeles (UCLA), Los Angeles, California 90095-1569.

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http://dx.doi.org/10.1101/cshperspect.a032383DOI Listing
December 2019

Structural basis of 7SK RNA 5'-γ-phosphate methylation and retention by MePCE.

Nat Chem Biol 2019 02 17;15(2):132-140. Epub 2018 Dec 17.

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41589-018-0188-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339579PMC
February 2019

Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.

Proc Natl Acad Sci U S A 2018 07 26;115(28):E6457-E6466. Epub 2018 Jun 26.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569

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http://dx.doi.org/10.1073/pnas.1806276115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048529PMC
July 2018

Structure of Telomerase with Telomeric DNA.

Cell 2018 05;173(5):1179-1190.e13

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.04.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995583PMC
May 2018

Structural biology of telomerase and its interaction at telomeres.

Curr Opin Struct Biol 2017 12 18;47:77-87. Epub 2017 Jul 18.

Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, CA 90095-1569, USA. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564310PMC
December 2017

Progress in Human and Tetrahymena Telomerase Structure Determination.

Annu Rev Biophys 2017 05 15;46:199-225. Epub 2017 Mar 15.

Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569; email: , ,

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http://dx.doi.org/10.1146/annurev-biophys-062215-011140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508521PMC
May 2017

Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes.

J Biol Chem 2017 Jan 28;292(1):217-228. Epub 2016 Nov 28.

From the Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202 and

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http://dx.doi.org/10.1074/jbc.M116.763664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217681PMC
January 2017

Structure and folding of the Tetrahymena telomerase RNA pseudoknot.

Nucleic Acids Res 2017 Jan 29;45(1):482-495. Epub 2016 Nov 29.

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, USA

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http://dx.doi.org/10.1093/nar/gkw1153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224487PMC
January 2017

hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA.

Nucleic Acids Res 2016 Nov 26;44(20):9977-9989. Epub 2016 Sep 26.

Department of Chemistry and Biochemistry, P.O. Box 951569, University of California, Los Angeles, CA 90095-1569, USA

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http://dx.doi.org/10.1093/nar/gkw833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175362PMC
November 2016

Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human.

Proc Natl Acad Sci U S A 2016 08 16;113(35):E5125-34. Epub 2016 Aug 16.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569; University of California Los Angeles-Department of Energy Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095

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http://dx.doi.org/10.1073/pnas.1607411113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024593PMC
August 2016

Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres.

FEBS J 2016 06 17;283(11):2044-50. Epub 2016 Mar 17.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/febs.13691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899323PMC
June 2016

Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.

Science 2015 Oct 15;350(6260):aab4070. Epub 2015 Oct 15.

Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. California Nanosystems Institute, UCLA, Los Angeles, CA 90095, USA. UCLA-U.S. Department of Energy (DOE) Institute of Genomics and Proteomics, UCLA, Los Angeles, CA 90095, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.aab4070
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http://dx.doi.org/10.1126/science.aab4070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687456PMC
October 2015

Back to the future of RNA structure.

Authors:
Juli Feigon

RNA 2015 Apr;21(4):611-2

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095-1569, USA

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http://dx.doi.org/10.1261/rna.050716.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371303PMC
April 2015

Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1.

J Mol Biol 2015 Feb 29;427(4):807-823. Epub 2014 Dec 29.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA; University of California Los Angeles-Department of Energy (UCLA-DOE) Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2014.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323627PMC
February 2015

Structure and function of preQ riboswitches.

Biochim Biophys Acta 2014 Oct 4;1839(10):939-950. Epub 2014 May 4.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA; UCLA-DOE Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S18749399140010
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http://dx.doi.org/10.1016/j.bbagrm.2014.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177978PMC
October 2014

Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function.

Nucleic Acids Res 2014 Mar 11;42(5):3395-408. Epub 2013 Dec 11.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569, USA, Advanced Analysis Center, Korea Institute of Science and Technology, Seoul, 136-791, Republic of Korea and Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1093/nar/gkt1276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950677PMC
March 2014

Structural determinants for ligand capture by a class II preQ1 riboswitch.

Proc Natl Acad Sci U S A 2014 Feb 27;111(6):E663-71. Epub 2014 Jan 27.

Department of Chemistry and Biochemistry and University of California Los Angeles-Department of Energy Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1400126111
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http://dx.doi.org/10.1073/pnas.1400126111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926045PMC
February 2014

Progress in structural studies of telomerase.

Curr Opin Struct Biol 2014 Feb 4;24:115-24. Epub 2014 Feb 4.

Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, CA 90095, USA; California Nanosystems Institute, University of California Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2014.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984607PMC
February 2014

Molecular mechanism of GTPase activation at the signal recognition particle (SRP) RNA distal end.

J Biol Chem 2013 Dec 22;288(51):36385-97. Epub 2013 Oct 22.

From the Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125 and.

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http://dx.doi.org/10.1074/jbc.M113.513614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868752PMC
December 2013

Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub.

Mol Cell Biol 2013 Oct 5;33(19):3962-71. Epub 2013 Aug 5.

Department of Molecular and Cell Biology, University of California, Berkeley, California, USA.

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http://dx.doi.org/10.1128/MCB.00792-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811867PMC
October 2013

Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo.

Proc Natl Acad Sci U S A 2013 Jul 17;110(27):10970-5. Epub 2013 Jun 17.

Department of Chemistry and Biochemistry and Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1073/pnas.1309590110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704002PMC
July 2013

The architecture of Tetrahymena telomerase holoenzyme.

Nature 2013 Apr 3;496(7444):187-92. Epub 2013 Apr 3.

Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature12062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817743PMC
April 2013

xRRM: a new class of RRM found in the telomerase La family protein p65.

RNA Biol 2013 Mar 17;10(3):353-9. Epub 2013 Jan 17.

Department of Chemistry and Biochemistry and the Molecular Biology Institute; University of California; Los Angeles, CA USA.

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http://dx.doi.org/10.4161/rna.23608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672277PMC
March 2013

Intrinsic dynamics of an extended hydrophobic core in the S. cerevisiae RNase III dsRBD contributes to recognition of specific RNA binding sites.

J Mol Biol 2013 Feb 28;425(3):546-62. Epub 2012 Nov 28.

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.jmb.2012.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557707PMC
February 2013

Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4 T) in the presence of Cs+ ions.

Angew Chem Int Ed Engl 2012 Aug 5;51(32):7952-5. Epub 2012 Jul 5.

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095-1569, USA.

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http://doi.wiley.com/10.1002/anie.201203459
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http://dx.doi.org/10.1002/anie.201203459DOI Listing
August 2012

Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65.

Mol Cell 2012 Jul 14;47(1):16-26. Epub 2012 Jun 14.

Department of Chemistry, and the Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.molcel.2012.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398246PMC
July 2012

Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain.

Angew Chem Int Ed Engl 2012 Jun 27;51(24):5876-9. Epub 2012 Apr 27.

Department of Chemistry and Biochemistry, Center for Molecular Biology of RNA, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1002/anie.201200526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483790PMC
June 2012

Architecture of human telomerase RNA.

Proc Natl Acad Sci U S A 2011 Dec 15;108(51):20325-32. Epub 2011 Aug 15.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1073/pnas.1100279108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251123PMC
December 2011

Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.

J Mol Biol 2011 Sep 25;411(5):927-42. Epub 2011 Jun 25.

Department of Chemistry and Biochemistry, and the Molecular Biology Institute, PO Box 951569,University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.jmb.2011.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156286PMC
September 2011

Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs.

Structure 2011 Jul;19(7):999-1010

Department of Chemistry and Biochemistry, P.O. Box 951569, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.str.2011.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143303PMC
July 2011

Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics.

J Am Chem Soc 2011 Apr 16;133(14):5190-3. Epub 2011 Mar 16.

Department of Chemistry and Biochemistry , University of California, Los Angeles, California 90095-1569, USA.

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http://dx.doi.org/10.1021/ja111769gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085290PMC
April 2011

Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA.

Proc Natl Acad Sci U S A 2010 Nov 21;107(44):18761-8. Epub 2010 Oct 21.

Department of Chemistry and Biochemistry, Molecular Biology Institute, PO Box 951569, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1073/pnas.1013269107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973926PMC
November 2010

Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA.

Nucleic Acids Res 2010 Oct 16;38(19):6746-56. Epub 2010 Jun 16.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/nar/gkq525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965242PMC
October 2010

Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA.

Mol Cell 2009 Mar 12;33(6):784-90. Epub 2009 Mar 12.

UCLA-DOE Institute for Genomics and Proteomics, University of California, Los Angeles, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.02.019DOI Listing
March 2009

Structure and functional studies of the CS domain of the essential H/ACA ribonucleoparticle assembly protein SHQ1.

J Biol Chem 2009 Jan 19;284(3):1906-16. Epub 2008 Nov 19.

Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1074/jbc.M807337200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615527PMC
January 2009

Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA.

J Mol Biol 2008 Dec 11;384(5):1249-61. Epub 2008 Oct 11.

Department of Chemistry and Biochemistry, P.O. Box 951569, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.jmb.2008.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660571PMC
December 2008

Structural and functional characterization of human telomerase RNA processing and cajal body localization signals.

Mol Cell 2007 Sep;27(6):869-81

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.molcel.2007.07.017DOI Listing
September 2007

H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification.

Proc Natl Acad Sci U S A 2007 Apr 5;104(16):6655-60. Epub 2007 Apr 5.

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1073/pnas.0701534104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871841PMC
April 2007

Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function.

RNA 2006 Aug 29;12(8):1475-85. Epub 2006 Jun 29.

Department of Molecular Biology and Biochemistry, University of South Bohemia, Czech Republic.

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http://dx.doi.org/10.1261/rna.112306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524899PMC
August 2006

Structure and function of telomerase RNA.

Curr Opin Struct Biol 2006 Jun 18;16(3):307-18. Epub 2006 May 18.

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/j.sbi.2006.05.005DOI Listing
June 2006

Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element.

Nucleic Acids Res 2006 1;34(3):816-25. Epub 2006 Feb 1.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1093/nar/gkj481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360744PMC
February 2006

Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.

RNA 2006 Jan;12(1):40-52

Department of Chemistry and Biochemistry, 607 Charles Young Drive East, P.O. Box 951569, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1261/rna.2221606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370884PMC
January 2006

Characterization of the cation and temperature dependence of DNA quadruplex hydrogen bond properties using high-resolution NMR.

J Am Chem Soc 2005 Oct;127(41):14466-72

Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, U.K.

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http://dx.doi.org/10.1021/ja0540369DOI Listing
October 2005

Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop.

J Mol Biol 2005 Aug;351(1):1-8

Jules Stein Eye Institute, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.jmb.2005.06.007DOI Listing
August 2005

Structure determination of protein/RNA complexes by NMR.

Methods Enzymol 2005 ;394:525-45

Department of Chemistry and Biochemistry, University of California, Los Angeles 90095, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)94022-6DOI Listing
June 2005

Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function.

Mol Cell 2005 Mar;17(5):671-82

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, USA

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http://dx.doi.org/10.1016/j.molcel.2005.01.017DOI Listing
March 2005

Structure of the XPC binding domain of hHR23A reveals hydrophobic patches for protein interaction.

Protein Sci 2004 Sep;13(9):2370-7

Department of Chemistry and Biochemistry, 405 Hilgard Avenue, P.O. Box 951569, University of California, Los Angeles, California 90095-1569, USA.

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http://dx.doi.org/10.1110/ps.04824304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2280024PMC
September 2004

Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III.

Proc Natl Acad Sci U S A 2004 Jun 18;101(22):8307-12. Epub 2004 May 18.

Department of Chemistry and Biochemistry and Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1073/pnas.0402627101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420390PMC
June 2004

Contributions of the RNA-binding and linker domains and RNA structure to the specificity and affinity of the nucleolin RBD12/NRE interaction.

Biochemistry 2004 Jun;43(22):6937-47

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, California 90095-1569, USA.

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http://dx.doi.org/10.1021/bi049904dDOI Listing
June 2004

Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.

J Mol Biol 2004 Apr;337(4):799-816

Department of Chemistry and Biochemistry, Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360400138
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http://dx.doi.org/10.1016/j.jmb.2004.01.056DOI Listing
April 2004

Specificity of the interaction between ubiquitin-associated domains and ubiquitin.

J Biol Chem 2004 Mar 5;279(12):11926-36. Epub 2004 Jan 5.

Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M312865200
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http://dx.doi.org/10.1074/jbc.M312865200DOI Listing
March 2004

DNA A-tract bending in three dimensions: solving the dA4T4 vs. dT4A4 conundrum.

Proc Natl Acad Sci U S A 2004 Feb 22;101(5):1177-82. Epub 2004 Jan 22.

National Center for Biomolecular Research, NMR Laboratory, Faculty of Science, Masaryk University, Kotlárská 2, CZ-611 37 Brno, Czech Republic.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0308143100
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http://dx.doi.org/10.1073/pnas.0308143100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC337026PMC
February 2004

New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes.

J Biomol NMR 2004 Jan;28(1):59-67

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, U.S.A.

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http://dx.doi.org/10.1023/B:JNMR.0000012861.95939.05DOI Listing
January 2004

YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA.

RNA 2003 Dec;9(12):1446-55

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370499PMC
http://dx.doi.org/10.1261/rna.5152303DOI Listing
December 2003

Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin.

Nucleic Acids Res 2003 Nov;31(22):6461-72

Department of Chemistry and Biochemistry, and Molecular Biology Institute, University of California, Los Angeles, CA 90095-1569, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC275560PMC
http://dx.doi.org/10.1093/nar/gkg866DOI Listing
November 2003

Structural determinants for the binding of ubiquitin-like domains to the proteasome.

EMBO J 2003 Sep;22(18):4634-45

Department of Chemistry and Biochemistry, 405 Hilgard Avenue, PO Box 951569, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1093/emboj/cdg467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC212733PMC
September 2003

Monitoring RNA base structure and dynamics using site-directed spin labeling.

Biochemistry 2003 Jun;42(22):6772-83

Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1021/bi027222pDOI Listing
June 2003

Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA.

Proc Natl Acad Sci U S A 2003 Jan 13;100(2):449-54. Epub 2003 Jan 13.

Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1073/pnas.242720799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC141015PMC
January 2003

The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding.

J Mol Biol 2002 Oct;323(2):263-84

Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1016/s0022-2836(02)00938-5DOI Listing
October 2002

Characterization of divalent cation localization in the minor groove of the A(n)T(n) and T(n)A(n) DNA sequence elements by (1)H NMR spectroscopy and manganese(II).

Biochemistry 2002 Aug;41(31):9900-10

Department of Chemistry and Biochemistry, University of California, 405 Hilgard Avenue, Los Angeles, CA 90095-1569, USA.

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http://dx.doi.org/10.1021/bi020159jDOI Listing
August 2002

Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions.

J Mol Biol 2002 Jun;319(5):1243-55

Department of Chemistry and Biochemistry, Molecular Biology Institute, University of California at Los Angeles, 90095-1569, USA.

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http://dx.doi.org/10.1016/S0022-2836(02)00302-9DOI Listing
June 2002

Determination of the glycosidic torsion angles in uniformly 13C-labeled nucleic acids from vicinal coupling constants 3J(C2)/4-H1' and 3J(C6)/8-H1'.

J Biomol NMR 2002 May;23(1):1-12

National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Koltlárská Brno, Czech Republic.

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http://dx.doi.org/10.1023/a:1015389118506DOI Listing
May 2002

Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A.

Biochemistry 2002 Apr;41(17):5404-14

Department of Biological Chemistry, UCLA School of Medicine, Los Angeles, California 90095-1737, USA.

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http://dx.doi.org/10.1021/bi012077lDOI Listing
April 2002