Publications by authors named "Juhani Leijala"

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Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam.

Case Rep Psychiatry 2021 5;2021:2140723. Epub 2021 Nov 5.

Department of Psychiatry, Central Hospital of Southern Ostrobothnia, Hanneksenrinne 7, FI-60220 Seinäjoki, Finland.

Benzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications including seizures, suicidal behavior, anxiety, and depression. Guidelines describe tapering protocols for modest doses; however, protocols for exceptionally high-dose BZD withdrawal are not well described. Herein, we describe a BZD tapering protocol for a patient with daily use of high-dose (1800 mg) oxazepam (OXP). The BZD tapering was administered in an inpatient psychiatric hospital, and the outcome was evaluated monthly after discharge for three months. This report describes a unique case of high-dose OXP withdrawal and also outlines an optional protocol to apply when clinicians encounter these unusual cases.
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Source
http://dx.doi.org/10.1155/2021/2140723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589494PMC
November 2021
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