Juha Saharinen

Juha Saharinen

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Juha Saharinen

Juha Saharinen

Publications by authors named "Juha Saharinen"

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Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R König Kay-Tee Khaw Lee M Kaplan Åsa Johansson A Cecile J W Janssens Wilmar Igl G Kees Hovingh Christian Hengstenberg Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Leif C Groop Elena Gonzalez Nelson B Freimer Jeanette Erdmann Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Ulf de Faire Gabriel Crawford Yii-der I Chen Mark J Caulfield S Matthijs Boekholdt Themistocles L Assimes Thomas Quertermous Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Herman A Taylor Stacey B Gabriel Hilma Holm Vilmundur Gudnason Ronald M Krauss Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt David P Strachan Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Sekar Kathiresan

PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1002607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315470PMC
September 2012

Inter-tissue networks between the basal forebrain, hippocampus, and prefrontal cortex in a model for depression caused by disturbed sleep.

J Neurogenet 2012 Sep 11;26(3-4):397-412. Epub 2012 Jul 11.

Public Health Genomics Unit and Institute for Molecular Medicine FIMM, National Institute for Health and Welfare, Helsinki, Finland.

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http://dx.doi.org/10.3109/01677063.2012.694932DOI Listing
September 2012

Biological, clinical and population relevance of 95 loci for blood lipids.

Authors:
Tanya M Teslovich Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Samuli Ripatti Daniel I Chasman Cristen J Willer Christopher T Johansen Sigrid W Fouchier Aaron Isaacs Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Yurii S Aulchenko Gudmar Thorleifsson Mary F Feitosa John Chambers Marju Orho-Melander Olle Melander Toby Johnson Xiaohui Li Xiuqing Guo Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Kijoung Song Jing Hua Zhao Xin Yuan Jian'an Luan Claudia Lamina Andreas Ziegler Weihua Zhang Robert Y L Zee Alan F Wright Jacqueline C M Witteman James F Wilson Gonneke Willemsen H-Erich Wichmann John B Whitfield Dawn M Waterworth Nicholas J Wareham Gérard Waeber Peter Vollenweider Benjamin F Voight Veronique Vitart Andre G Uitterlinden Manuela Uda Jaakko Tuomilehto John R Thompson Toshiko Tanaka Ida Surakka Heather M Stringham Tim D Spector Nicole Soranzo Johannes H Smit Juha Sinisalo Kaisa Silander Eric J G Sijbrands Angelo Scuteri James Scott David Schlessinger Serena Sanna Veikko Salomaa Juha Saharinen Chiara Sabatti Aimo Ruokonen Igor Rudan Lynda M Rose Robert Roberts Mark Rieder Bruce M Psaty Peter P Pramstaller Irene Pichler Markus Perola Brenda W J H Penninx Nancy L Pedersen Cristian Pattaro Alex N Parker Guillaume Pare Ben A Oostra Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Thomas Meitinger Ruth McPherson Mark I McCarthy Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Massimo Mangino Patrik K E Magnusson Gavin Lucas Robert Luben Ruth J F Loos Marja-Liisa Lokki Guillaume Lettre Claudia Langenberg Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Florian Kronenberg Inke R König Kay-Tee Khaw Jaakko Kaprio Lee M Kaplan Asa Johansson Marjo-Riitta Jarvelin A Cecile J W Janssens Erik Ingelsson Wilmar Igl G Kees Hovingh Jouke-Jan Hottenga Albert Hofman Andrew A Hicks Christian Hengstenberg Iris M Heid Caroline Hayward Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Ulf Gyllensten Candace Guiducci Leif C Groop Elena Gonzalez Christian Gieger Nelson B Freimer Luigi Ferrucci Jeanette Erdmann Paul Elliott Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Eco J C de Geus Ulf de Faire Gabriel Crawford Francis S Collins Yii-der I Chen Mark J Caulfield Harry Campbell Noel P Burtt Lori L Bonnycastle Dorret I Boomsma S Matthijs Boekholdt Richard N Bergman Inês Barroso Stefania Bandinelli Christie M Ballantyne Themistocles L Assimes Thomas Quertermous David Altshuler Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Linda S Adair Herman A Taylor Ingrid B Borecki Stacey B Gabriel James G Wilson Hilma Holm Unnur Thorsteinsdottir Vilmundur Gudnason Ronald M Krauss Karen L Mohlke Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt Jerome I Rotter Eric Boerwinkle David P Strachan Vincent Mooser Kari Stefansson Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Cornelia M van Duijn Leena Peltonen Gonçalo R Abecasis Michael Boehnke Sekar Kathiresan

Nature 2010 Aug;466(7307):707-13

Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/nature09270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039276PMC
August 2010

Gene expression patterns in a rodent model for depression.

Eur J Neurosci 2010 Apr 6;31(8):1465-73. Epub 2010 Apr 6.

Institute for Molecular Medicine FIMM, National Institute for Health and Welfare, Biomedicum, Helsinki, Finland.

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http://dx.doi.org/10.1111/j.1460-9568.2010.07166.xDOI Listing
April 2010

Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells.

Int J Cancer 2009 Aug;125(3):530-40

Department of General Neurology, Laboratory of Molecular Neuro-Oncology, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/ijc.24443DOI Listing
August 2009

Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.

BMC Med Genomics 2008 Nov 11;1:55. Epub 2008 Nov 11.

Biological Mechanisms and Prevention of Work-related Diseases, Health and Work Ability, Finnish Institute of Occupational Health, Topeliuksenkatu 41aA, FI-00250 Helsinki, Finland.

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http://dx.doi.org/10.1186/1755-8794-1-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612681PMC
November 2008

Critical immunological pathways are downregulated in APECED patient dendritic cells.

J Mol Med (Berl) 2008 Oct 4;86(10):1139-52. Epub 2008 Jul 4.

National Public Health Institute and FIMM, Institute for Molecular Medicine Finland, Biomedicum, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00109-008-0374-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685494PMC
October 2008

Functional interaction of AIRE with PIAS1 in transcriptional regulation.

Mol Immunol 2008 Apr;45(7):1847-62

Department of Molecular Medicine, National Public Health Institute, Biomedicum Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland.

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http://linkinghub.elsevier.com/retrieve/pii/S016158900700845
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http://dx.doi.org/10.1016/j.molimm.2007.10.045DOI Listing
April 2008

Unregulated smooth-muscle myosin in human intestinal neoplasia.

Proc Natl Acad Sci U S A 2008 Apr 7;105(14):5513-8. Epub 2008 Apr 7.

Department of Medical Genetics and Division of Pathology, HUSLAB and Haartman Institute, Helsinki University Central Hospital and Genome Scale Biology Program, Biomedicum Helsinki, University of Helsinki, 00014, Helsinki, Finland.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0801213105
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http://dx.doi.org/10.1073/pnas.0801213105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291082PMC
April 2008

CanGEM: mining gene copy number changes in cancer.

Nucleic Acids Res 2008 Jan 11;36(Database issue):D830-5. Epub 2007 Oct 11.

Genome Informatics Unit, Biomedicum Helsinki, Finland.

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http://dx.doi.org/10.1093/nar/gkm802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238975PMC
January 2008

Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response.

J Mol Med (Berl) 2007 Sep 26;85(9):971-83. Epub 2007 May 26.

Department of Molecular Medicine, National Public Health Institute, Biomedicum, Haartmaninkatu 8, 00290, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00109-007-0191-4DOI Listing
September 2007

Neural precursor cells from a fatal human motoneuron disease differentiate despite aberrant gene expression.

Dev Neurobiol 2007 Feb;67(3):270-84

Department of Molecular Medicine, National Public Health Institute, Biomedicum, Helsinki, Finland.

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http://dx.doi.org/10.1002/dneu.20350DOI Listing
February 2007

Identification of pathways regulating cell size and cell-cycle progression by RNAi.

Nature 2006 Feb;439(7079):1009-13

Molecular and Cancer Biology Program, Biomedicum Helsinki, PO Box 63 (Haartmaninkatu 8), FI-00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1038/nature04469DOI Listing
February 2006

Indicative oligodendrocyte dysfunction in spinal cords of human fetuses suffering from a lethal motoneuron disease.

J Neurobiol 2005 Dec;65(3):269-81

Department of Molecular Medicine, National Public Health Institute, Biomedicum, Helsinki, Finland.

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http://doi.wiley.com/10.1002/neu.20185
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http://dx.doi.org/10.1002/neu.20185DOI Listing
December 2005

Infantile onset spinocerebellar ataxia is caused by recessive mutations in mitochondrial proteins Twinkle and Twinky.

Hum Mol Genet 2005 Oct 31;14(20):2981-90. Epub 2005 Aug 31.

Department of Molecular Medicine, National Public Health Institute, University of Helsinki, Finland.

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http://dx.doi.org/10.1093/hmg/ddi328DOI Listing
October 2005

cDNA cloning, expression profile and genomic structure of a novel human transcript on chromosome 10q24, and its analyses as a candidate gene for infantile onset spinocerebellar ataxia.

Gene 2002 Oct;299(1-2):111-5

Department of Molecular Medicine, National Public Health Institute, Biomedicum Helsinki, Haartmaninkatu 8, FIN-00290 Helsinki, Finland.

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http://dx.doi.org/10.1016/s0378-1119(02)01019-3DOI Listing
October 2002

Secretion of human latent TGF-beta-binding protein-3 (LTBP-3) is dependent on co-expression of TGF-beta.

J Cell Sci 2002 Sep;115(Pt 17):3457-68

Departments of Virology and Pathology, Haartman Institute and Biomedicum Helsinki, University of Helsinki and Helsinki University Hospital, FIN-00014 Helsinki, Finland.

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September 2002