Judy M Wong

Judy M Y Wong

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Judy M Wong

Judy M Y Wong

Publications by authors named "Judy M Y Wong"

24Publications

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1PubMed Central Citations

Transcriptome-wide identification of transient RNA G-quadruplexes in human cells.

Nat Commun 2018 11 9;9(1):4730. Epub 2018 Nov 9.

Institut de Chimie Moléculaire (ICMUB), UBFC Dijon, CNRS UMR6302, 9, Rue Alain Savary, 21078, Dijon, France.

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http://www.nature.com/articles/s41467-018-07224-8
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http://dx.doi.org/10.1038/s41467-018-07224-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226477PMC
November 2018

Transient Telomerase Inhibition with Imetelstat Impacts DNA Damage Signals and Cell-Cycle Kinetics.

Mol Cancer Res 2018 08 14;16(8):1215-1225. Epub 2018 May 14.

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0772DOI Listing
August 2018

Cellular Detection of G-Quadruplexes by Optical Imaging Methods.

Curr Protoc Cell Biol 2017 Sep 1;76:4.33.1-4.33.19. Epub 2017 Sep 1.

Institut de Chimie Moléculaire, ICMUB CNRS UMR6302, UBFC Dijon, France.

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http://doi.wiley.com/10.1002/cpcb.29
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http://dx.doi.org/10.1002/cpcb.29DOI Listing
September 2017

Quantification of Pseudouridine Levels in Cellular RNA Pools with a Modified HPLC-UV Assay.

Genes (Basel) 2017 Sep 5;8(9). Epub 2017 Sep 5.

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

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http://www.mdpi.com/2073-4425/8/9/219
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http://dx.doi.org/10.3390/genes8090219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615352PMC
September 2017

Real-time and quantitative fluorescent live-cell imaging with quadruplex-specific red-edge probe (G4-REP).

Biochim Biophys Acta Gen Subj 2017 May 10;1861(5 Pt B):1312-1320. Epub 2016 Dec 10.

Institut de Chimie Moléculaire, ICMUB CNRS UMR6302, UBFC Dijon, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2016.11.046DOI Listing
May 2017

Investigation of chromosome X inactivation and clinical phenotypes in female carriers of DKC1 mutations.

Am J Hematol 2016 12 4;91(12):1215-1220. Epub 2016 Nov 4.

Molecular and Cellular Pharmacology Group, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/ajh.24545DOI Listing
December 2016

Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic method.

Sci Rep 2016 08 18;6:32141. Epub 2016 Aug 18.

Institut de Chimie Moléculaire, ICMUB CNRS UMR6302, UBFC, 21078 Dijon, France.

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http://dx.doi.org/10.1038/srep32141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989495PMC
August 2016

Visualization of RNA-Quadruplexes in Live Cells.

J Am Chem Soc 2015 Jul 23;137(26):8521-5. Epub 2015 Jun 23.

†Institute of Molecular Chemistry, University of Dijon, ICMUB CNRS, UMR6302 Dijon, France.

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http://dx.doi.org/10.1021/jacs.5b03413DOI Listing
July 2015

Severity of X-linked dyskeratosis congenita (DKCX) cellular defects is not directly related to dyskerin (DKC1) activity in ribosomal RNA biogenesis or mRNA translation.

Hum Mutat 2013 Dec 21;34(12):1698-707. Epub 2013 Oct 21.

Molecular and Cellular Pharmacology Group, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

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http://doi.wiley.com/10.1002/humu.22447
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http://dx.doi.org/10.1002/humu.22447DOI Listing
December 2013

Structure-function relationship and biogenesis regulation of the human telomerase holoenzyme.

FEBS J 2013 Jul 3;280(14):3194-204. Epub 2013 May 3.

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/febs.12272DOI Listing
July 2013

Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.

Cancer Res 2010 Nov 13;70(21):8684-94. Epub 2010 Sep 13.

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2227DOI Listing
November 2010

Dyskeratosis congenita: the first NIH clinical research workshop.

Pediatr Blood Cancer 2009 Sep;53(3):520-3

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA.

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http://dx.doi.org/10.1002/pbc.22061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739803PMC
September 2009

Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference.

Mol Cell Biol 2008 Oct 18;28(20):6510-20. Epub 2008 Aug 18.

Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA.

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http://dx.doi.org/10.1128/MCB.00777-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577424PMC
October 2008

Telomerase as a clinical target: current strategies and potential applications.

Exp Gerontol 2007 Jan-Feb;42(1-2):102-12. Epub 2006 Jun 30.

Division of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.

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http://dx.doi.org/10.1016/j.exger.2006.05.011DOI Listing
October 2007

Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita.

Genes Dev 2006 Oct 2;20(20):2848-58. Epub 2006 Oct 2.

Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.

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http://www.genesdev.org/cgi/doi/10.1101/gad.1476206
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http://dx.doi.org/10.1101/gad.1476206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1619937PMC
October 2006

The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.

Proc Natl Acad Sci U S A 2005 Jun 31;102(23):8222-7. Epub 2005 May 31.

Department of Medical Oncology and Biostatistical Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0503095102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1149439PMC
June 2005

Telomerase RNA deficiency in peripheral blood mononuclear cells in X-linked dyskeratosis congenita.

Hum Genet 2004 Oct 3;115(5):448-55. Epub 2004 Sep 3.

Department of Molecular and Cell Biology, University of California, Berkeley 94720-3204, USA.

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http://dx.doi.org/10.1007/s00439-004-1178-7DOI Listing
October 2004

Human telomerase reverse transcriptase motifs required for elongation of a telomeric substrate.

J Biol Chem 2003 Dec 17;278(52):52531-6. Epub 2003 Oct 17.

Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720-3204, USA.

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http://dx.doi.org/10.1074/jbc.M311359200DOI Listing
December 2003

Telomere maintenance and disease.

Lancet 2003 Sep;362(9388):983-8

Department of Molecular and Cell Biology, University of California at Berkeley, 401 Barker Hall, Berkeley, CA 94720-3204, USA.

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http://dx.doi.org/10.1016/S0140-6736(03)14369-3DOI Listing
September 2003

Subnuclear shuttling of human telomerase induced by transformation and DNA damage.

Nat Cell Biol 2002 Sep;4(9):731-6

Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3204, USA.

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http://www.nature.com/articles/ncb846
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http://dx.doi.org/10.1038/ncb846DOI Listing
September 2002

Polymorphisms in the human AH receptor.

Chem Biol Interact 2002 Sep;141(1-2):161-87

Division of Clinical Pharmacology, Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8.

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http://dx.doi.org/10.1016/s0009-2797(02)00071-6DOI Listing
September 2002