Judy M Coulson

Judy M Coulson

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Judy M Coulson

Judy M Coulson

Publications by authors named "Judy M Coulson"

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Targeting centrosome amplification, an Achilles' heel of cancer.

Biochem Soc Trans 2019 Sep 10. Epub 2019 Sep 10.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YG, U.K.

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http://dx.doi.org/10.1042/BST20190034DOI Listing
September 2019

Isoform-specific Ras signaling is growth factor dependent.

Mol Biol Cell 2019 04 20;30(9):1108-1117. Epub 2019 Feb 20.

Division of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, United Kingdom.

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http://dx.doi.org/10.1091/mbc.E18-10-0676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724511PMC
April 2019

RAS variant signalling.

Biochem Soc Trans 2018 10 3;46(5):1325-1332. Epub 2018 Oct 3.

Division of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, U.K.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST20180173
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http://dx.doi.org/10.1042/BST20180173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195641PMC
October 2018

Recent breakthroughs in metastatic uveal melanoma: a cause for optimism?

Future Oncol 2018 Jun 9;14(14):1335-1338. Epub 2018 May 9.

Liverpool Ocular Oncology Research Group, Department of Molecular & Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, UK.

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http://dx.doi.org/10.2217/fon-2018-0116DOI Listing
June 2018

The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity.

Oncogene 2018 04 12;37(17):2326-2342. Epub 2018 Feb 12.

Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1038/s41388-017-0092-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916918PMC
April 2018

Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics.

Pigment Cell Melanoma Res 2018 03 15;31(2):253-266. Epub 2017 Oct 15.

Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/pcmr.12650DOI Listing
March 2018

New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome.

Cancer Res 2018 01 18;78(1):15-29. Epub 2017 Dec 18.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-2291DOI Listing
January 2018

Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma.

J Pathol Clin Res 2018 Jan 13;4(1):26-38. Epub 2017 Nov 13.

Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.

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http://dx.doi.org/10.1002/cjp2.86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783957PMC
January 2018

Transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle.

FASEB J 2017 12 17;31(12):5268-5282. Epub 2017 Aug 17.

Stem Cells, Ageing, and Molecular Physiology Research Unit, Exercise Metabolism and Adaptation Research Group, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom;

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http://dx.doi.org/10.1096/fj.201700089RRDOI Listing
December 2017

Regulation of the cell cycle and centrosome biology by deubiquitylases.

Biochem Soc Trans 2017 Oct 12;45(5):1125-1136. Epub 2017 Sep 12.

Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, U.K.

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http://dx.doi.org/10.1042/BST20170087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652225PMC
October 2017

Quantification of spatiotemporal patterns of Ras isoform expression during development.

Sci Rep 2017 01 24;7:41297. Epub 2017 Jan 24.

Division of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, L69 3BX, UK.

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http://www.nature.com/articles/srep41297
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http://dx.doi.org/10.1038/srep41297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259795PMC
January 2017

Combined Analyses of the VHL and Hypoxia Signaling Axes in an Isogenic Pairing of Renal Clear Cell Carcinoma Cells.

J Proteome Res 2015 Dec 16;14(12):5263-72. Epub 2015 Nov 16.

Cellular and Molecular Physiology Department, University of Liverpool , Liverpool L69 3BX, United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.5b00692DOI Listing
December 2015

Plasticity of mammary cell boundaries governed by EGF and actin remodeling.

Cell Rep 2014 Sep 18;8(6):1722-1730. Epub 2014 Sep 18.

Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.08.026DOI Listing
September 2014

Decoding RAS isoform and codon-specific signalling.

Biochem Soc Trans 2014 Aug;42(4):742-6

*Division of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, U.K.

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http://dx.doi.org/10.1042/BST20140057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961500PMC
August 2014

Deubiquitylases from genes to organism.

Physiol Rev 2013 Jul;93(3):1289-315

Cellular and Molecular Physiology, Institute of Translational Medicine, and Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.

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http://physrev.physiology.org/content/physrev/93/3/1289.full
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http://physrev.physiology.org/cgi/doi/10.1152/physrev.00002.
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http://dx.doi.org/10.1152/physrev.00002.2013DOI Listing
July 2013

The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit.

Cell Cycle 2013 Jun 20;12(12):1964-77. Epub 2013 May 20.

Cellular & Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.4161/cc.25035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735711PMC
June 2013

Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.

J Biol Chem 2012 Dec 26;287(51):43007-18. Epub 2012 Oct 26.

Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M112.386938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522295PMC
December 2012

Cellular functions of the DUBs.

J Cell Sci 2012 Jan;125(Pt 2):277-86

Physiological Laboratory, Institute of Translational Medicine, University of Liverpool, Crown Street, L69 3BX Liverpool, UK.

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http://dx.doi.org/10.1242/jcs.090985DOI Listing
January 2012

Isoform-specific localization of the deubiquitinase USP33 to the Golgi apparatus.

Traffic 2011 Nov 25;12(11):1563-74. Epub 2011 Aug 25.

Physiological Laboratory, Institute of Translational Medicine, Cellular and Molecular Physiology, University of Liverpool, Crown Street, L69 3BX Liverpool, United Kingdom.

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http://dx.doi.org/10.1111/j.1600-0854.2011.01261.xDOI Listing
November 2011

Emerging roles of deubiquitinases in cancer-associated pathways.

IUBMB Life 2010 Feb;62(2):140-57

Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Liverpool, L69 3BX, UK.

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http://dx.doi.org/10.1002/iub.300DOI Listing
February 2010

SCG3 transcript in peripheral blood is a prognostic biomarker for REST-deficient small cell lung cancer.

Clin Cancer Res 2009 Jan;15(1):274-83

Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1163DOI Listing
January 2009

Real-time polymerase chain reaction to follow the response of muscle to training.

Artif Organs 2008 Aug;32(8):630-3

Department of Human Anatomy and Cell Biology, School of Biomedical Sciences, the University of Liverpool, Liverpool, UK.

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http://doi.wiley.com/10.1111/j.1525-1594.2008.00613.x
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http://dx.doi.org/10.1111/j.1525-1594.2008.00613.xDOI Listing
August 2008

Deciphering histone 2A deubiquitination.

Genome Biol 2008 Jan 23;9(1):202. Epub 2008 Jan 23.

Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Crown St, Liverpool L69 3BX, UK.

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http://dx.doi.org/10.1186/gb-2008-9-1-202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395231PMC
January 2008

Site-specific phosphorylation of SCG10 in neuronal plasticity: role of Ser73 phosphorylation by N-methyl D-aspartic acid receptor activation in rat hippocampus.

Neurosci Lett 2006 Apr 20;396(3):241-6. Epub 2005 Dec 20.

Department of Molecular Genetics, National Institute for Longevity Sciences, 36-3 Gengo, Morioka, Oobu, 474-8522, Japan.

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http://dx.doi.org/10.1016/j.neulet.2005.11.043DOI Listing
April 2006

Transcriptional regulation: cancer, neurons and the REST.

Authors:
Judy M Coulson

Curr Biol 2005 Sep;15(17):R665-8

Physiological Laboratory and Department of Human Anatomt & Cell Biology, School of Biomedical Sciences, University of Liverpool, Crown St, Liverpol L69 3BX, UK.

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http://dx.doi.org/10.1016/j.cub.2005.08.032DOI Listing
September 2005

Roles for USF-2 in lung cancer proliferation and bronchial carcinogenesis.

J Pathol 2005 Jun;206(2):151-9

Cancer Research UK Department of Clinical Oncology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1002/path.1775DOI Listing
June 2005

Regulation of the cell-specific calcitonin/calcitonin gene-related peptide enhancer by USF and the Foxa2 forkhead protein.

J Biol Chem 2004 Nov 22;279(48):49948-55. Epub 2004 Sep 22.

Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M406659200
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http://dx.doi.org/10.1074/jbc.M406659200DOI Listing
November 2004

Genetic abnormalities in plasma DNA of patients with lung cancer and other respiratory diseases.

Int J Cancer 2004 Jul;110(6):891-5

Cancer Research UK Department of Clinical Oncology, University of Nottingham and Nottingham City Hospital, Nottingham, United Kingdom.

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http://dx.doi.org/10.1002/ijc.20156DOI Listing
July 2004

Detection of small cell lung cancer by RT-PCR for neuropeptides, neuropeptide receptors, or a splice variant of the neuron restrictive silencer factor.

Methods Mol Med 2003 ;75:335-52

Departments of Physiology and Human Anatomy, University of Liverpool, Liverpool, UK.

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May 2003

Neuroendocrine phenotype of small cell lung cancer.

Methods Mol Med 2003 ;74:61-73

Departments of Physiology and Human Anatomy, University of Liverpool, Liverpool, UK.

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April 2003

Cross-talk between hypoxic and circadian pathways: cooperative roles for hypoxia-inducible factor 1alpha and CLOCK in transcriptional activation of the vasopressin gene.

Mol Cell Neurosci 2003 Mar;22(3):396-404

Molecular Neuroendocrinology Research Group, University Research Center for Neuroendocrinology, University of Bristol, Bristol Royal Infirmary, UK.

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March 2003