Judy H Cho

Judy H Cho

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Judy H Cho

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Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.

Cell 2019 Sep 29;178(6):1493-1508.e20. Epub 2019 Aug 29.

Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.08.008DOI Listing
September 2019

Genetic Factors and the Intestinal Microbiome Guide Development of Microbe-Based Therapies for Inflammatory Bowel Diseases.

Gastroenterology 2019 06 14;156(8):2174-2189. Epub 2019 Mar 14.

Department of Pathology, University of California-San Diego, La Jolla, California; Chiba University and University of California-San Diego Center for Mucosal Immunology, Allergy, and Vaccines (CU-UCSD cMAV), La Jolla, California. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568267PMC
June 2019

Gut microbiota density influences host physiology and is shaped by host and microbial factors.

Elife 2019 01 22;8. Epub 2019 Jan 22.

Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, United States.

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https://elifesciences.org/articles/40553
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http://dx.doi.org/10.7554/eLife.40553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342524PMC
January 2019

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.

Gastroenterology 2017 01 28;152(1):206-217.e2. Epub 2016 Sep 28.

Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.09.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164948PMC
January 2017

The Promise of Epigenetics. Has It Delivered New Insights?

Authors:
Judy H Cho

Dig Dis 2016 16;34(1-2):12-9. Epub 2016 Mar 16.

Genetics and Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA.

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http://dx.doi.org/10.1159/000442919DOI Listing
December 2016

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF.

Gastroenterology 2016 10 1;151(4):710-723.e2. Epub 2016 Jul 1.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037012PMC
October 2016

Genetic Predictors of Benign Course of Ulcerative Colitis-A North American Inflammatory Bowel Disease Genetics Consortium Study.

Inflamm Bowel Dis 2016 10;22(10):2311-6

*Division of Gastroenterology, McGill University Health Center, Montreal, Quebec, Canada; †Montreal Heart Institute, Montreal, Quebec, Canada; ‡Université de Montréal, Montreal, Quebec, Canada; §Division of Gastroenterology, Mount Sinai Hospital, Toronto, Ontario, Canada; ‖Division of Gastroenterology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; ¶Section of Digestive Diseases, Yale University, New Haven, Connecticut; **Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; ††Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; ‡‡Translational Genomics Group, F. Widjaja Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; §§Division of Gastroenterology, University of Chicago, Chicago, Illinois; and ‖‖Meyerhoff Inflammatory Bowel Diseases Center, Division of Gastroenterology, Johns Hopkins School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1097/MIB.0000000000000913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098421PMC
October 2016

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Nat Commun 2016 08 9;7:12342. Epub 2016 Aug 9.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1038/ncomms12342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980482PMC
August 2016

Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease.

Inflamm Bowel Dis 2016 Jan;22(1):20-7

*Department of Pediatrics and †Center for Research Informatics, The University of Chicago, Chicago, Illinois; ‡Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom; §Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; ‖Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; ¶F. Widjaja Family Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; **Department of Genetics and Genomic Sciences and ††Zane Cohen Centre for Digestive Diseases, Department of Medicine, Mount Sinai Hospital, The University of Toronto, Toronto, Ontario, Canada; and ‡‡Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1097/MIB.0000000000000610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679526PMC
January 2016

Genetics of Inflammatory Bowel Diseases.

Gastroenterology 2015 Oct 7;149(5):1163-1176.e2. Epub 2015 Aug 7.

Departments of Genetics and Medicine, Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://ac.els-cdn.com/S0016508511002009/1-s2.0-S001650851100
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http://www.cell.com/trends/immunology/pdf/S1471-4906(13)0005
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http://ac.els-cdn.com/S0016508502158963/1-s2.0-S001650850215
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http://dx.doi.org/10.1053/j.gastro.2015.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915781PMC
October 2015

Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes.

Hum Mol Genet 2015 Jul 1;24(14):4147-57. Epub 2015 May 1.

Department of Genetics and Genomic Sciences, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA,

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http://dx.doi.org/10.1093/hmg/ddv142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560067PMC
July 2015

Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies.

Nat Med 2015 Jul 29;21(7):730-8. Epub 2015 Jun 29.

Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.

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http://search.proquest.com/openview/318418030fdad9cf1b913ae5
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http://dx.doi.org/10.1038/nm.3897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716342PMC
July 2015

Bridging the gap between host immune response and intestinal dysbiosis in inflammatory bowel disease: does immunoglobulin A mark the spot?

Clin Gastroenterol Hepatol 2015 May 25;13(5):842-6. Epub 2015 Feb 25.

Division of Pediatric Gastroenterology, Nutrition and Liver Diseases, Department of Pediatrics, Hasbro Children's Hospital/Rhode Island Hospital, Providence, Rhode Island; Warren Alpert School of Medicine at Brown University, Providence, Rhode Island.

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https://linkinghub.elsevier.com/retrieve/pii/S15423565150016
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http://dx.doi.org/10.1016/j.cgh.2015.02.028DOI Listing
May 2015

Effector CD4+ T cell expression signatures and immune-mediated disease associated genes.

PLoS One 2012 8;7(6):e38510. Epub 2012 Jun 8.

Department of Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038510PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371029PMC
February 2015

Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease.

Cell 2014 Aug;158(5):1000-1010

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA; Howard Hughes Medical Institute, Yale University, New Haven, CT 06510, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174347PMC
August 2014

Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele.

Immunity 2014 May;40(5):734-46

Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, CT 06510, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157904PMC
May 2014

Age and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cells.

PLoS One 2013 1;8(3):e57746. Epub 2013 Mar 1.

Department of Medicine and Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057746PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585933PMC
August 2013

Empirical Bayes correction for the Winner's Curse in genetic association studies.

Genet Epidemiol 2013 Jan 25;37(1):60-8. Epub 2012 Sep 25.

Section of Digestive Diseases, Yale School of Medicine, New Haven, Connecticut 06511, USA.

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http://dx.doi.org/10.1002/gepi.21683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048064PMC
January 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Genomics and the multifactorial nature of human autoimmune disease.

N Engl J Med 2011 Oct;365(17):1612-23

Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, CT 06520-8019, USA.

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http://dx.doi.org/10.1056/NEJMra1100030DOI Listing
October 2011

Improved risk prediction for Crohn's disease with a multi-locus approach.

Hum Mol Genet 2011 Jun 22;20(12):2435-42. Epub 2011 Mar 22.

Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1093/hmg/ddr116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298027PMC
June 2011

Recent insights into the genetics of inflammatory bowel disease.

Gastroenterology 2011 May;140(6):1704-12

Department of Medicine and Genetics, Yale University, New Haven, Connecticut, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001650851100200
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http://dx.doi.org/10.1053/j.gastro.2011.02.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947143PMC
May 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010

Assessment of DNA methylation at the interferon regulatory factor 5 (IRF5) promoter region in inflammatory bowel diseases.

Int J Colorectal Dis 2010 May 2;25(5):553-6. Epub 2010 Feb 2.

Section of Pediatric Gastroenterology, Baylor College of Medicine, Houston, TX 77030-2399, USA.

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http://dx.doi.org/10.1007/s00384-010-0874-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751749PMC
May 2010

Genome-wide association studies: present status and future directions.

Authors:
Judy H Cho

Gastroenterology 2010 May 16;138(5):1668-1672.e1. Epub 2010 Mar 16.

Department of Medicine and Genetics, Yale University, New Haven, Connecticut 06510, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.03.028DOI Listing
May 2010

Unraveling the genetics of autoimmunity.

Cell 2010 Mar;140(6):791-7

Department of Immunobiology, Yale University, New Haven, CT 06520, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674100023
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http://dx.doi.org/10.1016/j.cell.2010.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491807PMC
March 2010

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors:
Marcin Imielinski Robert N Baldassano Anne Griffiths Richard K Russell Vito Annese Marla Dubinsky Subra Kugathasan Jonathan P Bradfield Thomas D Walters Patrick Sleiman Cecilia E Kim Aleixo Muise Kai Wang Joseph T Glessner Shehzad Saeed Haitao Zhang Edward C Frackelton Cuiping Hou James H Flory George Otieno Rosetta M Chiavacci Robert Grundmeier Massimo Castro Anna Latiano Bruno Dallapiccola Joanne Stempak Debra J Abrams Kent Taylor Dermot McGovern Gary Silber Iwona Wrobel Antonio Quiros Jeffrey C Barrett Sarah Hansoul Dan L Nicolae Judy H Cho Richard H Duerr John D Rioux Steven R Brant Mark S Silverberg Kent D Taylor M Michael Barmuda Alain Bitton Themistocles Dassopoulos Lisa Wu Datta Todd Green Anne M Griffiths Emily O Kistner Michael T Murtha Miguel D Regueiro Jerome I Rotter L Philip Schumm A Hillary Steinhart Stephen R Targan Ramnik J Xavier Cécile Libioulle Cynthia Sandor Mark Lathrop Jacques Belaiche Olivier Dewit Ivo Gut Simon Heath Debby Laukens Myriam Mni Paul Rutgeerts André Van Gossum Diana Zelenika Denis Franchimont J P Hugot Martine de Vos Severine Vermeire Edouard Louis Lon R Cardon Carl A Anderson Hazel Drummond Elaine Nimmo Tariq Ahmad Natalie J Prescott Clive M Onnie Sheila A Fisher Jonathan Marchini Jilur Ghori Suzannah Bumpstead Rhian Gwillam Mark Tremelling Panos Delukas John Mansfield Derek Jewell Jack Satsangi Christopher G Mathew Miles Parkes Michel Georges Mark J Daly Melvin B Heyman George D Ferry Barbara Kirschner Jessica Lee Jonah Essers Richard Grand Michael Stephens Arie Levine David Piccoli John Van Limbergen Salvatore Cucchiara Dimitri S Monos Stephen L Guthery Lee Denson David C Wilson Straun F A Grant Mark Daly Mark S Silverberg Jack Satsangi Hakon Hakonarson

Nat Genet 2009 Dec 15;41(12):1335-40. Epub 2009 Nov 15.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267927PMC
December 2009

Inflammatory bowel disease.

N Engl J Med 2009 Nov;361(21):2066-78

Department of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMra0804647
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http://dx.doi.org/10.1056/NEJMra0804647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491806PMC
November 2009

IL-23 and autoimmunity: new insights into the pathogenesis of inflammatory bowel disease.

Annu Rev Med 2009 ;60:97-110

Section of Digestive Diseases, Departments of 1Medicine, Yale University, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1146/annurev.med.60.051407.123757DOI Listing
September 2009

Recent progress in inflammatory bowel disease genetics.

Authors:
Judy H Cho

Adv Exp Med Biol 2006 ;579:24-34

University of Chicago, Illinois, USA.

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http://dx.doi.org/10.1007/0-387-33778-4_3DOI Listing
April 2009

The genetics and immunopathogenesis of inflammatory bowel disease.

Authors:
Judy H Cho

Nat Rev Immunol 2008 Jun;8(6):458-66

Inflammatory Bowel Disease Center, Section of Digestive Diseases, Yale University, 333 Cedar Street, LMP 1080, New Haven, Connecticut 06520, USA.

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http://www.nature.com/articles/nri2340
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http://dx.doi.org/10.1038/nri2340DOI Listing
June 2008

Inflammatory bowel disease: genetic and epidemiologic considerations.

Authors:
Judy H Cho

World J Gastroenterol 2008 Jan;14(3):338-47

Inflammatory Bowel Disease Center, Yale University, 300 Cedar Street, New Haven, CT 06519, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679123PMC
http://dx.doi.org/10.3748/wjg.14.338DOI Listing
January 2008

Chronic stimulation of Nod2 mediates tolerance to bacterial products.

Proc Natl Acad Sci U S A 2007 Dec 21;104(49):19440-5. Epub 2007 Nov 21.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.0706097104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148308PMC
December 2007

The genetics of inflammatory bowel disease.

Gastroenterology 2007 Oct;133(4):1327-39

Inflammatory Bowel Disease Center, Section of Digestive Diseases, Yale University, New Haven, Connecticut 06520-8019, USA.

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http://dx.doi.org/10.1053/j.gastro.2007.08.032DOI Listing
October 2007

Bugging of the intestinal mucosa.

N Engl J Med 2007 Aug;357(7):708-10

Department of Medicine, University of Chicago, Chicago, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMcibr073420
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http://dx.doi.org/10.1056/NEJMcibr073420DOI Listing
August 2007

Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease.

Clin Gastroenterol Hepatol 2007 Jul 16;5(7):857-64. Epub 2007 May 16.

Department of Medicine, Palo Alto Veterans Affairs Medical Center and Stanford University Digestive Disease Center, Palo Alto, California 94304, USA.

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http://dx.doi.org/10.1016/j.cgh.2007.02.017DOI Listing
July 2007

Smoking and inflammatory bowel disease: trends in familial and sporadic cohorts.

Inflamm Bowel Dis 2007 May;13(5):573-9

Midwest Gastroenterology Associates, Louisville, Kentucky, USA.

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http://dx.doi.org/10.1002/ibd.20043DOI Listing
May 2007

Inflammatory bowel disease genetics: Nod2.

Annu Rev Med 2007 ;58:401-16

Department of Medicine, Yale University, New Haven, Connecticut 06510, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.med.58.0617
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http://dx.doi.org/10.1146/annurev.med.58.061705.145024DOI Listing
April 2007

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

Science 2006 Dec 26;314(5804):1461-3. Epub 2006 Oct 26.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, University of Pittsburgh Medical Center Presbyterian, Mezzanine Level, C-Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1126/science.1135245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410764PMC
December 2006

Finding inflammatory bowel disease genes will lead to a cure.

Authors:
Judy H Cho

Can J Gastroenterol 2006 Oct;20(10):641-2

Inflammatory Bowel Disease Center, Yale University, New Haven, Connecticut 06519, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660790PMC
http://dx.doi.org/10.1155/2006/561643DOI Listing
October 2006

Functional consequences of NOD2 (CARD15) mutations.

Inflamm Bowel Dis 2006 Jul;12(7):641-50

Department of Medicine, Section of Gastroenterology, University of Chicago, Chicago, Illinois 60637, USA.

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https://academic.oup.com/ibdjournal/article/12/7/641-650/468
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http://dx.doi.org/10.1097/01.MIB.0000225332.83861.5fDOI Listing
July 2006

Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease.

Am J Physiol Gastrointest Liver Physiol 2006 Jun 26;290(6):G1157-63. Epub 2006 Jan 26.

Department of Pathology and Laboratory Medicine, Epithelial Pathobiology Unit, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1152/ajpgi.00544.2005DOI Listing
June 2006

Inducing intestinal growth.

N Engl J Med 2005 Nov;353(21):2297-9

Department of Medicine, University of Chicago, Chicago, USA.

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http://dx.doi.org/10.1056/NEJMcibr053367DOI Listing
November 2005

Advances in the genetics of inflammatory bowel disease.

Authors:
Judy H Cho

Curr Gastroenterol Rep 2004 Dec;6(6):467-73

University of Chicago, 5841 South Maryland Avenue, MC 6084, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s11894-004-0068-4DOI Listing
December 2004

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Sep;10(5):513-20

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1097/00054725-200409000-00004DOI Listing
September 2004

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations.

Hum Mol Genet 2004 Aug 15;13(16):1715-25. Epub 2004 Jun 15.

The Martin Boyer Laboratories, Gastroenterology Section, Department of Medicine, The University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddh182DOI Listing
August 2004

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Jan;10(1):15-22

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/00054725-200401000-00002DOI Listing
January 2004

MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.

Am J Hum Genet 2003 Dec 7;73(6):1282-92. Epub 2003 Nov 7.

The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180394PMC
http://dx.doi.org/10.1086/379927DOI Listing
December 2003

Defining complex contributions of NOD2/CARD15 gene mutations, age at onset, and tobacco use on Crohn's disease phenotypes.

Inflamm Bowel Dis 2003 Sep;9(5):281-9

The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Dept. of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, U.S.A.

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http://dx.doi.org/10.1097/00054725-200309000-00001DOI Listing
September 2003

Significant role of genetics in IBD: the NOD2 gene.

Authors:
Judy H Cho

Rev Gastroenterol Disord 2003 ;3 Suppl 1:S18-22

Committee of Genetics, University of Chicago, Chicago, IL, USA.

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June 2003

The genetics of inflammatory bowel disease.

Gastroenterology 2003 Feb;124(2):521-36

The Martin Boyer Laboratories, Gastroenterology Section, Department of Medicine, University of Chicago Hospitals, Illinois 60637, USA.

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http://dx.doi.org/10.1053/gast.2003.50045DOI Listing
February 2003

Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan.

Gastroenterology 2003 Jan;124(1):140-6

Martin Boyer Laboratories, Gastroenterology Section, Department of Medicine, University of Chicago Hospitals, Chicago, Illinois, USA.

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http://dx.doi.org/10.1053/gast.2003.50019DOI Listing
January 2003

Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage.

Hum Mol Genet 2002 Oct;11(21):2599-606

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1093/hmg/11.21.2599DOI Listing
October 2002

Update on genetics of inflammatory bowel disease.

Curr Opin Gastroenterol 2002 Jul;18(4):410-5

Hôpital Robert Debré and Fondation Jean Dausset, Paris, France.

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http://dx.doi.org/10.1097/00001574-200207000-00003DOI Listing
July 2002