Judith V M G Bovée

Judith V M G Bovée

UNVERIFIED PROFILE

Are you Judith V M G Bovée?   Register this Author

Register author
Judith V M G Bovée

Judith V M G Bovée

Publications by authors named "Judith V M G Bovée"

Are you Judith V M G Bovée?   Register this Author

100Publications

2602Reads

31Profile Views

Soft tissue aneurysmal bone cyst: six new cases with imaging details, molecular pathology, and review of the literature.

Skeletal Radiol 2019 Jul 2;48(7):1059-1067. Epub 2019 Jan 2.

Department of Radiology, C-2-S, Leiden University Medical Center, PO Box 9600, 2300RC, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00256-018-3135-xDOI Listing
July 2019

Conventional chondrosarcoma with focal clear cell change: a clinicopathological and molecular analysis.

Histopathology 2019 Jul 11. Epub 2019 Jul 11.

Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.13952DOI Listing
July 2019

Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway.

J Bone Oncol 2019 Apr 29;15:100222. Epub 2019 Jan 29.

Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbo.2019.100222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360255PMC
April 2019

Molecular Pathology of Bone Tumors.

J Mol Diagn 2019 Mar 18;21(2):171-182. Epub 2018 Dec 18.

Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2018.11.002DOI Listing
March 2019

Does CSF1 overexpression or rearrangement influence biological behaviour in tenosynovial giant cell tumours of the knee?

Histopathology 2019 Jan 11;74(2):332-340. Epub 2018 Nov 11.

Department of Cell and Chemical biology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/his.13744
Publisher Site
http://dx.doi.org/10.1111/his.13744DOI Listing
January 2019

Prevalence and Clinical Features of Mazabraud Syndrome: A Multicenter European Study.

J Bone Joint Surg Am 2019 Jan;101(2):160-168

Department of Orthopaedic Surgery (B.C.J.M., M.A.J.v.d.S., and S.P.D.D.), Endocrinology Division, Department of Medicine (N.M.A.-D. and N.A.T.H.), and Department of Pathology (J.V.M.G.B.), Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2106/JBJS.18.00062DOI Listing
January 2019

Jason L. Hornick: Practical soft tissue pathology: a diagnostic approach, 2nd edition.

Virchows Arch 2018 Dec 29;473(6):785-786. Epub 2018 Aug 29.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-018-2440-zDOI Listing
December 2018

Successful disinfection of femoral head bone graft using high hydrostatic pressure.

Cell Tissue Bank 2018 Sep 20;19(3):333-340. Epub 2017 Dec 20.

Department of Medical Microbiology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10561-017-9678-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133176PMC
September 2018

Molecular Analysis of Gene Fusions in Bone and Soft Tissue Tumors by Anchored Multiplex PCR-Based Targeted Next-Generation Sequencing.

J Mol Diagn 2018 09 20;20(5):653-663. Epub 2018 Aug 20.

Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2018.05.007DOI Listing
September 2018

Low-grade central fibroblastic osteosarcoma may be differentiated from its mimicker desmoplastic fibroma by genetic analysis.

Clin Sarcoma Res 2018 23;8:16. Epub 2018 Aug 23.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

View Article

Download full-text PDF

Source
https://clinicalsarcomaresearch.biomedcentral.com/articles/1
Publisher Site
http://dx.doi.org/10.1186/s13569-018-0104-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106748PMC
August 2018

Telatinib Is an Effective Targeted Therapy for Pseudomyogenic Hemangioendothelioma.

Clin Cancer Res 2018 06 6;24(11):2678-2687. Epub 2018 Mar 6.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-17-3512DOI Listing
June 2018

The role of metabolic enzymes in mesenchymal tumors and tumor syndromes: genetics, pathology, and molecular mechanisms.

Lab Invest 2018 04 16;98(4):414-426. Epub 2018 Jan 16.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41374-017-0003-6DOI Listing
April 2018

IWR-1, a tankyrase inhibitor, attenuates Wnt/β-catenin signaling in cancer stem-like cells and inhibits in vivo the growth of a subcutaneous human osteosarcoma xenograft.

Cancer Lett 2018 02 8;414:1-15. Epub 2017 Nov 8.

Pharmacology and Experimental Therapeutics, IBILI - Faculty of Medicine, University of Coimbra, Coimbra, Azinhaga de Sta. Comba, Celas, 3000-354, Portugal; CNC.IBILI, University of Coimbra, Coimbra, Portugal; CIMAGO, University of Coimbra, Coimbra, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2017.11.004DOI Listing
February 2018

A remarkable response to pazopanib, despite recurrent liver toxicity, in a patient with a high grade endometrial stromal sarcoma, a case report.

BMC Cancer 2018 01 22;18(1):92. Epub 2018 Jan 22.

Department of Medical Oncology, Leiden University Medical Centre, Albinusdreef 2, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-018-3999-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778698PMC
January 2018

NAD Synthesis Pathway Interference Is a Viable Therapeutic Strategy for Chondrosarcoma.

Mol Cancer Res 2017 12 31;15(12):1714-1721. Epub 2017 Aug 31.

Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-17-0293DOI Listing
December 2017

Integrating Morphology and Genetics in the Diagnosis of Cartilage Tumors.

Surg Pathol Clin 2017 Sep;10(3):537-552

Department of Pathology, Leiden University Medical Center, PO Box 9600, L1-Q, 2300 RC Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.path.2017.04.005DOI Listing
September 2017

Vascular Tumors of Bone: The Evolvement of a Classification Based on Molecular Developments.

Surg Pathol Clin 2017 Sep;10(3):621-635

Department of Pathology, Leiden University Medical Center, Postzone L1-Q, Postbus 9600, Leiden 2300 RC, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18759181173006
Publisher Site
http://dx.doi.org/10.1016/j.path.2017.04.003DOI Listing
September 2017

Molecular Pathology of Bone Tumors: What Have We Learned and How Does It Affect Daily Practice?

Surg Pathol Clin 2017 Sep;10(3):xiii-xiv

Professor, Department of Pathology, Leiden University Medical Center, PO Box 9600, L1-Q 2300 RC, Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.path.2017.06.001DOI Listing
September 2017

An experimental guideline for the analysis of histologically heterogeneous tumors by MALDI-TOF mass spectrometry imaging.

Biochim Biophys Acta Proteins Proteom 2017 Jul 8;1865(7):957-966. Epub 2016 Oct 8.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands; Fondazione Pisana per la Scienza ONLUS, Pisa, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbapap.2016.09.020DOI Listing
July 2017

Prognostic Metabolite Biomarkers for Soft Tissue Sarcomas Discovered by Mass Spectrometry Imaging.

J Am Soc Mass Spectrom 2017 02 21;28(2):376-383. Epub 2016 Nov 21.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13361-016-1544-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227002PMC
February 2017

Increased PD-L1 and T-cell infiltration in the presence of HLA class I expression in metastatic high-grade osteosarcoma: a rationale for T-cell-based immunotherapy.

Cancer Immunol Immunother 2017 01 16;66(1):119-128. Epub 2016 Nov 16.

Department of Pathology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00262-016-1925-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222929PMC
January 2017

Cutaneous nodular fasciitis with genetic analysis: a case series.

J Cutan Pathol 2016 Dec;43(12):1143-1149

Department of Pathology and Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cup.12828DOI Listing
December 2016

Panobinostat-A Potential Treatment for Metastasized Ewing Sarcoma? A Case Report.

Pediatr Blood Cancer 2016 10 1;63(10):1840-3. Epub 2016 Jun 1.

Department of Medical Oncology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.26077DOI Listing
October 2016

Molecular Pathogenesis and Diagnostic, Prognostic and Predictive Molecular Markers in Sarcoma.

Surg Pathol Clin 2016 Sep;9(3):457-73

Department of Pathology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.path.2016.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988391PMC
September 2016

Molecular oncogenesis of chondrosarcoma: impact for targeted treatment.

Curr Opin Oncol 2016 07;28(4):314-22

aDepartment of Clinical Oncology bDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCO.0000000000000300DOI Listing
July 2016

High-grade sarcoma diagnosis and prognosis: Biomarker discovery by mass spectrometry imaging.

Proteomics 2016 06;16(11-12):1802-13

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201500514DOI Listing
June 2016

DOG1 expression in giant-cell-containing bone tumours.

Histopathology 2016 May 21;68(6):942-5. Epub 2015 Dec 21.

Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.12873DOI Listing
May 2016

Tissue factor associates with survival and regulates tumour progression in osteosarcoma.

Thromb Haemost 2016 05 14;115(5):1025-33. Epub 2016 Jan 14.

Henri H. Versteeg, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands, Tel.: +31 715263872, Fax: +31 71526755, E-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1160/TH15-07-0541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428546PMC
May 2016

Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4.

J Cell Physiol 2016 04 9;231(4):876-86. Epub 2015 Sep 9.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.25179DOI Listing
April 2016

CORR Insights(®): Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-β as Involved in the Pathogenesis of Osteosarcoma.

Clin Orthop Relat Res 2016 Jan 12;474(1):190-2. Epub 2015 Nov 12.

Department of Pathology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11999-015-4620-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686491PMC
January 2016

Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling.

Cancer Lett 2016 Jan 11;370(2):286-95. Epub 2015 Nov 11.

Pharmacology and Experimental Therapeutics, IBILI - Faculty of Medicine, University of Coimbra, Coimbra, Portugal; CNC.IBILI, University of Coimbra, Coimbra, Portugal; Center of Investigation in Environment, Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, Coimbra, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2015.11.013DOI Listing
January 2016

Ewing sarcoma: The clinical relevance of the insulin-like growth factor 1 and the poly-ADP-ribose-polymerase pathway.

Eur J Cancer 2016 Jan 5;53:171-80. Epub 2016 Jan 5.

Department of Clinical Oncology, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2015.09.009DOI Listing
January 2016

Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee.

Eur Radiol 2015 Dec 21;25(12):3480-7. Epub 2015 May 21.

Department of Radiology, C2-S, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-015-3764-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636526PMC
December 2015

Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor.

Am J Surg Pathol 2015 Dec;39(12):1701-7

Departments of *Medical Oncology †Pathology ∥Radiation Oncology, Leiden University Medical Centre, Leiden, The Netherlands ‡Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Centre, Nashville, TN §Department of Pathology, Sarcoma Research Center, The University of Texas M.D. Anderson Cancer Center, Houston, TX ¶Robert J. Tomsich Pathology and Laboratory Medicine Institute, and Molecular Genetics, Cleveland Clinic, Taussig Cancer Centre and Lerner Research Institute, Cleveland, OH.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAS.0000000000000510DOI Listing
December 2015

Brain Region-Specific Dynamics of On-Tissue Protein Digestion Using MALDI Mass Spectrometry Imaging.

J Proteome Res 2015 Dec 13;14(12):5348-54. Epub 2015 Nov 13.

Center for Proteomics and Metabolomics, Leiden University Medical Center , Leiden 2333 ZA, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jproteome.5b00849DOI Listing
December 2015

Histology-Guided High-Resolution Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging.

Anal Chem 2015 Dec 4;87(24):11978-83. Epub 2015 Dec 4.

Center for Proteomics and Metabolomics, Leiden University Medical Center , Einthovenweg 20, 2333ZC Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.5b03610DOI Listing
December 2015

Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study.

PLoS One 2014 23;9(7):e103056. Epub 2014 Jul 23.

Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; The Netherlands Genomics Initiative, sponsored by the NCHA, Leiden-Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103056PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108379PMC
November 2015

A translocation t(6;14) in two cases of leiomyosarcoma: Molecular cytogenetic and array-based comparative genomic hybridization characterization.

Cancer Genet 2015 Nov 31;208(11):537-44. Epub 2015 Jul 31.

Department of Molecular Cell Biology, LUMC, Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cancergen.2015.07.005DOI Listing
November 2015

Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin.

Oncotarget 2015 Nov;6(34):36113-25

Division of Toxicology, Leiden/Academic Center for Drug Research, Leiden University, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.5333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742165PMC
November 2015

Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype.

Histopathology 2015 Oct 23;67(4):483-90. Epub 2015 Mar 23.

Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.12666DOI Listing
October 2015

Fusion events lead to truncation of FOS in epithelioid hemangioma of bone.

Genes Chromosomes Cancer 2015 Sep 14;54(9):565-74. Epub 2015 Jul 14.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22269DOI Listing
September 2015

Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.

J Pathol 2015 Jul 30;236(3):348-59. Epub 2015 Mar 30.

Division of Toxicology, Leiden Academic Centre for Drug Research, Leiden University, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/path.4528DOI Listing
July 2015

Current State and Future Challenges of Mass Spectrometry Imaging for Clinical Research.

Anal Chem 2015 Jul 7;87(13):6426-33. Epub 2015 Apr 7.

†Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.5b00416DOI Listing
July 2015

MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis.

Genes Chromosomes Cancer 2015 Jun 31;54(6):361-8. Epub 2015 Mar 31.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22247DOI Listing
June 2015

NY-ESO-1 (CTAG1B) expression in mesenchymal tumors.

Mod Pathol 2015 Apr 21;28(4):587-95. Epub 2014 Nov 21.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2014.155DOI Listing
April 2015

Array CGH analysis identifies two distinct subgroups of primary angiosarcoma of bone.

Genes Chromosomes Cancer 2015 Feb 18;54(2):72-81. Epub 2014 Sep 18.

Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22219DOI Listing
February 2015

An orthotopic mouse model for chondrosarcoma of bone provides an in vivo tool for drug testing.

Virchows Arch 2015 Jan 21;466(1):101-9. Epub 2014 Oct 21.

Department of Pathology, Leiden University Medical Center, Albinusdreef 2, 2333ZA, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-014-1670-yDOI Listing
January 2015

In reply.

Oncologist 2014 Nov;19(11):1208

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2014-0332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221381PMC
November 2014

Outcome of advanced, unresectable conventional central chondrosarcoma.

Cancer 2014 Oct 3;120(20):3159-64. Epub 2014 Jul 3.

Department of Clinical Oncology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.28845DOI Listing
October 2014

Somatic activating ARAF mutations in Langerhans cell histiocytosis.

Blood 2014 May 20;123(20):3152-5. Epub 2014 Mar 20.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2013-06-511139DOI Listing
May 2014

GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.

Nat Genet 2014 May 23;46(5):474-7. Epub 2014 Mar 23.

Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2927DOI Listing
May 2014

The clinical approach toward giant cell tumor of bone.

Oncologist 2014 May 9;19(5):550-61. Epub 2014 Apr 9.

Departments of Orthopedic Surgery, Clinical Oncology, Radiology, and Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://theoncologist.alphamedpress.org/cgi/doi/10.1634/theon
Publisher Site
http://dx.doi.org/10.1634/theoncologist.2013-0432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012970PMC
May 2014

Primary Ewing sarcoma of the iris.

Lancet 2014 Jan 16;383(9913):256. Epub 2013 Aug 16.

Department of Ophthalmology, Leiden University Medical Center, Leiden, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(13)60183-XDOI Listing
January 2014

The CpG island methylator phenotype: what's in a name?

Cancer Res 2013 Oct 25;73(19):5858-68. Epub 2013 Jun 25.

Authors' Affiliations: Departments of Epidemiology and Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht; Department of Surgery, Orbis Medical Center, Sittard-Geleen; Department of Pathology, Leiden University Medical Center, Leiden; Department of Neurology, Erasmus University Medical Center, Erasmus University, Rotterdam, the Netherlands; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium; and The Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-4306DOI Listing
October 2013

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.

Cancer 2013 Oct 31;119(20):3696-702. Epub 2013 Jul 31.

Sarcoma Service, Department of Surgery, Scientific Institute for Research, Hospitalization, and Health Care (IRCCS) Foundation, National Cancer Institute, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.28271DOI Listing
October 2013

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma.

Hematol Oncol Clin North Am 2013 Oct 26;27(5):1021-48. Epub 2013 Aug 26.

Department of Pathology, Leiden University Medical Center, PO Box 9600, L1-Q, Leiden RC 2300, The Netherlands.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08898588130010
Publisher Site
http://dx.doi.org/10.1016/j.hoc.2013.07.012DOI Listing
October 2013

Active TGF-β signaling and decreased expression of PTEN separates angiosarcoma of bone from its soft tissue counterpart.

Mod Pathol 2013 Sep 19;26(9):1211-21. Epub 2013 Apr 19.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2013.56DOI Listing
September 2013

Mediator complex subunit 12 exon 2 mutation analysis in different subtypes of smooth muscle tumors confirms genetic heterogeneity.

Hum Pathol 2013 Aug 19;44(8):1597-604. Epub 2013 Mar 19.

Department of Pathology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2013.01.006DOI Listing
August 2013

Functional profiling of receptor tyrosine kinases and downstream signaling in human chondrosarcomas identifies pathways for rational targeted therapy.

Clin Cancer Res 2013 Jul 28;19(14):3796-807. Epub 2013 May 28.

Ludwig Center at Dana-Farber/Harvard and Center for Sarcoma and Bone Oncology, Department of Medical Oncology, Harvard Medical School, Boston, Massachusetts 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-3647DOI Listing
July 2013