Judith C Deutekom

Judith C T van Deutekom

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Judith C Deutekom

Judith C T van Deutekom

Publications by authors named "Judith C T van Deutekom"

30Publications

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1PubMed Central Citations

Dose-dependent pharmacokinetic profiles of 2'-O-methyl phosphorothioate antisense oligonucleotidesin mdx mice.

Nucleic Acid Ther 2013 Jun 2;23(3):228-37. Epub 2013 May 2.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands .

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http://dx.doi.org/10.1089/nat.2012.0398DOI Listing
June 2013

Development of antisense-mediated exon skipping as a treatment for duchenne muscular dystrophy.

Ann N Y Acad Sci 2009 Sep;1175:71-9

Duchenne Muscular Dystrophy Genetic Therapy Group, Department of Human Genetics, Leiden University, Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04973.xDOI Listing
September 2009

Antisense-mediated exon skipping to correct IL-12Rbeta1 deficiency in T cells.

Blood 2009 May 3;113(19):4548-55. Epub 2009 Mar 3.

Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1182/blood-2008-12-196220DOI Listing
May 2009

Assessment of the feasibility of exon 45-55 multiexon skipping for Duchenne muscular dystrophy.

BMC Med Genet 2008 Dec 1;9:105. Epub 2008 Dec 1.

DMD Genetic Therapy Group, Department of Human Genetics, Leiden University, Medical Center, Postzone S4-P, PO Box 9600, 2300RC, Leiden, The Netherlands.

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http://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2350-9-105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2611974PMC
December 2008

Generation and characterization of transgenic mice with the full-length human DMD gene.

J Biol Chem 2008 Feb 13;283(9):5899-907. Epub 2007 Dec 13.

Center for Human and Clinical Genetics, Leiden University Medical Center, Postal Zone S4-P, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M709410200
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http://dx.doi.org/10.1074/jbc.M709410200DOI Listing
February 2008

Antisense-induced exon skipping for duplications in Duchenne muscular dystrophy.

BMC Med Genet 2007 Jul 5;8:43. Epub 2007 Jul 5.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1186/1471-2350-8-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931584PMC
July 2007

Exploring the frontiers of therapeutic exon skipping for Duchenne muscular dystrophy by double targeting within one or multiple exons.

Mol Ther 2006 Sep 6;14(3):401-7. Epub 2006 Jun 6.

DMD Genetic Therapy Group, Center for Human and Clinical Genetics, Leiden University Medical Center, RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.ymthe.2006.02.022DOI Listing
September 2006

Entries in the Leiden Duchenne muscular dystrophy mutation database: an overview of mutation types and paradoxical cases that confirm the reading-frame rule.

Muscle Nerve 2006 Aug;34(2):135-44

Leiden University Medical Center, Department of Human Genetics, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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http://doi.wiley.com/10.1002/mus.20586
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http://dx.doi.org/10.1002/mus.20586DOI Listing
August 2006

Gene expression profiling to monitor therapeutic and adverse effects of antisense therapies for Duchenne muscular dystrophy.

Pharmacogenomics 2006 Apr;7(3):281-97

Leiden University Medical Center, Center for Human and Clinical Genetics, Room S-04-003, Postbus 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.2217/14622416.7.3.281DOI Listing
April 2006

Gene therapy: the 'pro-sense' approach to Duchenne muscular dystrophy.

Eur J Hum Genet 2005 May;13(5):518-9

Center for Human and Clinical Genetics, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands.

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http://dx.doi.org/10.1038/sj.ejhg.5201381DOI Listing
May 2005

Large-scale gene expression analysis of human skeletal myoblast differentiation.

Neuromuscul Disord 2004 Sep;14(8-9):507-18

Center for Human and Clinical Genetics, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S096089660400092
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http://dx.doi.org/10.1016/j.nmd.2004.03.008DOI Listing
September 2004

Antisense-induced multiexon skipping for Duchenne muscular dystrophy makes more sense.

Am J Hum Genet 2004 Jan 16;74(1):83-92. Epub 2003 Dec 16.

Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181915PMC
http://dx.doi.org/10.1086/381039DOI Listing
January 2004

Advances in Duchenne muscular dystrophy gene therapy.

Nat Rev Genet 2003 Oct;4(10):774-83

Center for Human and Clinical Genetics, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands.

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http://www.nature.com/articles/nrg1180
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http://dx.doi.org/10.1038/nrg1180DOI Listing
October 2003

Therapeutic antisense-induced exon skipping in cultured muscle cells from six different DMD patients.

Hum Mol Genet 2003 Apr;12(8):907-14

Center for Human and Clinical Genetics, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddg100DOI Listing
April 2003

Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy.

Neuromuscul Disord 2002 Oct;12 Suppl 1:S71-7

Department of Human Genetics, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands.

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http://dx.doi.org/10.1016/s0960-8966(02)00086-xDOI Listing
October 2002