Judit Marsillach

Judit Marsillach

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Judit Marsillach

Judit Marsillach

Publications by authors named "Judit Marsillach"

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Evaluating the link between Paraoxonase-1 levels and Alzheimer's disease development.

Minerva Med 2019 Jun 11;110(3):238-250. Epub 2018 Oct 11.

Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.23736/S0026-4806.18.05875-5DOI Listing
June 2019

Paraoxonase-1 and Early-Life Environmental Exposures.

Ann Glob Health 2016 Jan-Feb;82(1):100-10

Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA; Department of Genome Sciences, University of Washington, Seattle, WA. Electronic address:

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http://dx.doi.org/10.1016/j.aogh.2016.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916371PMC
January 2018

Metals and Paraoxonases.

Adv Neurobiol 2017 ;18:85-111

Department of Medicine (Division of Medical Genetics), University of Washington, 4225 Roosevelt Way NE, Suite 100, Seattle, WA, 98105, USA.

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http://link.springer.com/10.1007/978-3-319-60189-2_5
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http://dx.doi.org/10.1007/978-3-319-60189-2_5DOI Listing
December 2017

Developmental expression of paraoxonase 2.

Chem Biol Interact 2016 Nov 7;259(Pt B):168-174. Epub 2016 Apr 7.

Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, United States; Dept. of Neuroscience, University of Parma, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055469PMC
http://dx.doi.org/10.1016/j.cbi.2016.04.001DOI Listing
November 2016

Paraoxonases-1, -2 and -3: What are their functions?

Chem Biol Interact 2016 Nov 26;259(Pt B):51-62. Epub 2016 May 26.

Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA; Department of Neuroscience, University of Parma, Parma, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2016.05.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391248PMC
November 2016

Announcing our finalists.

Bioanalysis 2015 7;7(13):1667-73. Epub 2015 Jul 7.

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http://dx.doi.org/10.4155/bio.15.90DOI Listing
April 2016

Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase.

PLoS One 2014 15;9(10):e110054. Epub 2014 Oct 15.

Department of Medicine (Division of Medical Genetics), University of Washington, Seattle, Washington, United States; Department of Genome Sciences, University of Washington, Seattle, Washington, United States.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110054PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198189PMC
June 2015

Paraoxonase-3 is depleted from the high-density lipoproteins of autoimmune disease patients with subclinical atherosclerosis.

J Proteome Res 2015 May 13;14(5):2046-54. Epub 2015 Mar 13.

¶Kidney Research Institute, University of Washington, 325 Ninth Avenue, Seattle, Washington 98104, United States.

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http://dx.doi.org/10.1021/pr5011586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434596PMC
May 2015

Paraoxonase-1 inhibits oxidized low-density lipoprotein-induced metabolic alterations and apoptosis in endothelial cells: a nondirected metabolomic study.

Mediators Inflamm 2013 22;2013:156053. Epub 2013 May 22.

Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C Sant Joan, 43201 Reus, Catalonia, Spain.

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http://dx.doi.org/10.1155/2013/156053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674710PMC
December 2013

Impaired paraoxonase-1 status in obese children. Relationships with insulin resistance and metabolic syndrome.

Clin Biochem 2013 Dec 10;46(18):1830-6. Epub 2013 Sep 10.

Unitat de Pediatria, Institut d'Investigació Sanitària Pere Virgili, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2013.08.020DOI Listing
December 2013

Pharmacogenetics of paraoxonase activity: elucidating the role of high-density lipoprotein in disease.

Pharmacogenomics 2013 Sep;14(12):1495-515

Departments of Genome Sciences & Medicine (Division of Medical Genetics), University of Washington School of Medicine, Box 357720, University of Washington, Seattle, WA 98195-7720, USA.

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http://dx.doi.org/10.2217/pgs.13.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888096PMC
September 2013

Paraoxonase-1 is associated with corneal endothelial cell alterations in patients with chronic obstructive pulmonary disease.

Invest Ophthalmol Vis Sci 2013 Aug 28;54(8):5852-8. Epub 2013 Aug 28.

Ophthalmology Service, Hospital Universitari Sant Joan de Reus, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Catalonia, Spain.

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http://dx.doi.org/10.1167/iovs.13-11951DOI Listing
August 2013

Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity.

Toxicology 2013 May 31;307:115-22. Epub 2012 Jul 31.

Dept. of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0300483X120028
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http://dx.doi.org/10.1016/j.tox.2012.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516631PMC
May 2013

Protein adducts as biomarkers of exposure to organophosphorus compounds.

Toxicology 2013 May 20;307:46-54. Epub 2012 Dec 20.

Departments of Medicine (Division of Medical Genetics) and Genome Sciences, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.tox.2012.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747771PMC
May 2013

Paraoxonase-1 deficiency is associated with severe liver steatosis in mice fed a high-fat high-cholesterol diet: a metabolomic approach.

J Proteome Res 2013 Apr 8;12(4):1946-55. Epub 2013 Mar 8.

Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili , Reus, Spain.

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http://dx.doi.org/10.1021/pr400050uDOI Listing
April 2013

Proteomic analysis of adducted butyrylcholinesterase for biomonitoring organophosphorus exposures.

Chem Biol Interact 2013 Mar 2;203(1):85-90. Epub 2012 Nov 2.

Dept of Medicine (Division of Medical Genetics), University of Washington, 98195 Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.cbi.2012.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108156PMC
March 2013

Serum paraoxonase-3 concentration is associated with insulin sensitivity in peripheral artery disease and with inflammation in coronary artery disease.

Atherosclerosis 2012 Feb 22;220(2):545-51. Epub 2011 Nov 22.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C. Sant Joan s/n, 43201 Reus, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.11.021DOI Listing
February 2012

Serum paraoxonase-3 concentration in HIV-infected patients. Evidence for a protective role against oxidation.

J Lipid Res 2012 Jan 14;53(1):168-74. Epub 2011 Oct 14.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1194/jlr.P018457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243473PMC
January 2012

Serum paraoxonase-3 concentration is associated with the severity of hepatic impairment in patients with chronic liver disease.

Clin Biochem 2011 Nov 10;44(16):1320-4. Epub 2011 Aug 10.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2011.08.003DOI Listing
November 2011

Biomarkers of organophosphorus (OP) exposures in humans.

Neurotoxicology 2011 Oct 8;32(5):656-60. Epub 2011 Jul 8.

Department of Medicine, Division Medical Genetics, University of Washington, Seattle, WA 98195-7720, United States.

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http://dx.doi.org/10.1016/j.neuro.2011.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279568PMC
October 2011

Interrelationships between paraoxonase-1 and monocyte chemoattractant protein-1 in the regulation of hepatic inflammation.

Adv Exp Med Biol 2010 ;660:5-18

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, C. Sant Joan s/n, 43201-Reus, Catalunya, Spain.

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http://dx.doi.org/10.1007/978-1-60761-350-3_2DOI Listing
September 2011

Measurement of serum PON-3 concentration: method evaluation, reference values, and influence of genotypes in a population-based study.

J Lipid Res 2011 May 17;52(5):1055-61. Epub 2011 Feb 17.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Catalonia, Spain.

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http://dx.doi.org/10.1194/jlr.D014134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073463PMC
May 2011

Immunohistochemical analysis of paraoxonases-1 and 3 in human atheromatous plaques.

Eur J Clin Invest 2011 Mar 21;41(3):308-14. Epub 2010 Oct 21.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, Reus, Catalunya, Spain.

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http://dx.doi.org/10.1111/j.1365-2362.2010.02411.xDOI Listing
March 2011

Paraoxonase-1 in female infertility: a possible role against oxidative stress-induced inflammation.

Fertil Steril 2010 Aug 25;94(3):1132-4. Epub 2010 Jan 25.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Reus, Catalunya, Spain.

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http://dx.doi.org/10.1016/j.fertnstert.2009.11.043DOI Listing
August 2010

Decreased paraoxonase-1 activity is associated with alterations of high-density lipoprotein particles in chronic liver impairment.

Lipids Health Dis 2010 May 14;9:46. Epub 2010 May 14.

Centre de Recerca Biomèdica, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C, Sant Joan s/n, 43201 Reus, Catalunya, Spain.

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http://dx.doi.org/10.1186/1476-511X-9-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877049PMC
May 2010

Methodological constraints in interpreting serum paraoxonase-1 activity measurements: an example from a study in HIV-infected patients.

Lipids Health Dis 2010 Mar 25;9:32. Epub 2010 Mar 25.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Reus, Catalunya, Spain.

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http://dx.doi.org/10.1186/1476-511X-9-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852375PMC
March 2010

Paraoxonase-1 gene haplotypes are associated with metabolic disturbances, atherosclerosis, and immunologic outcome in HIV-infected patients.

J Infect Dis 2010 Feb;201(4):627-34

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Lleida, Spain.

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http://dx.doi.org/10.1086/650312DOI Listing
February 2010

Hepatic monocyte chemoattractant protein-1 is upregulated by dietary cholesterol and contributes to liver steatosis.

Cytokine 2009 Dec 12;48(3):273-9. Epub 2009 Sep 12.

Centre de Recerca Biomèdica, Hospital Universitari Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, c/Sant Joan s/n, 43201 Reus, Spain.

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http://dx.doi.org/10.1016/j.cyto.2009.08.006DOI Listing
December 2009

Increased PAFAH and oxidized lipids are associated with inflammation and atherosclerosis in hypercholesterolemic pigs.

Arterioscler Thromb Vasc Biol 2009 Dec 1;29(12):2041-6. Epub 2009 Oct 1.

Atherosclerosis and Metabolism Unit, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, Belgium.

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http://dx.doi.org/10.1161/ATVBAHA.109.196592DOI Listing
December 2009

Serum concentrations of extracellular fatty acid synthase in patients with steatohepatitis.

Clin Chem Lab Med 2009 ;47(9):1097-9

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1515/CCLM.2009.259DOI Listing
November 2009

Pharmacological and lifestyle factors modulating serum paraoxonase-1 activity.

Mini Rev Med Chem 2009 Jul;9(8):911-20

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, C. Sant Joan s/n, 43201 Reus, Catalunya, Spain.

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July 2009

The paraoxonases: role in human diseases and methodological difficulties in measurement.

Crit Rev Clin Lab Sci 2009 ;46(2):83-106

Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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http://www.tandfonline.com/doi/full/10.1080/1040836080261087
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http://dx.doi.org/10.1080/10408360802610878DOI Listing
April 2009

The measurement of the lactonase activity of paraoxonase-1 in the clinical evaluation of patients with chronic liver impairment.

Clin Biochem 2009 Jan 21;42(1-2):91-8. Epub 2008 Oct 21.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2008.09.120DOI Listing
January 2009

Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease.

BMC Gastroenterol 2009 Jan 14;9. Epub 2009 Jan 14.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, C, Sant Joan s/n, 43201 Reus, Spain.

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http://dx.doi.org/10.1186/1471-230X-9-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632645PMC
January 2009

Immunohistochemical analysis of paraoxonases-1, 2, and 3 expression in normal mouse tissues.

Free Radic Biol Med 2008 Jul 11;45(2):146-57. Epub 2008 Apr 11.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S08915849080017
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http://dx.doi.org/10.1016/j.freeradbiomed.2008.03.023DOI Listing
July 2008

Serum paraoxonase undergoes inhibition and proteolysis during experimental acute pancreatitis.

J Gastrointest Surg 2008 May 11;12(5):891-9. Epub 2008 Mar 11.

Department of Ischemia and Inflammation, Institut d'Investigacions Biomèdiques de Barcelona (IIBB)-Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, Spain.

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http://dx.doi.org/10.1007/s11605-008-0502-2DOI Listing
May 2008

Measurement of serum paraoxonase-1 activity as a potential biomarker for chronic liver impairment.

Clin Chim Acta 2007 Nov-Dec;386(1-2):114-5. Epub 2007 Jul 25.

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http://dx.doi.org/10.1016/j.cca.2007.07.016DOI Listing
January 2008

Changes in the expression of genes related to apoptosis and fibrosis pathways in CCl4-treated rats.

Mol Cell Biochem 2008 Jan 16;308(1-2):101-9. Epub 2007 Oct 16.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, C. Sant Joan s/n, 43201 Reus (Catalunya), Spain.

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http://link.springer.com/10.1007/s11010-007-9617-0
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http://dx.doi.org/10.1007/s11010-007-9617-0DOI Listing
January 2008

Moderately high folic acid supplementation exacerbates experimentally induced liver fibrosis in rats.

Exp Biol Med (Maywood) 2008 Jan;233(1):38-47

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, Reus, Spain.

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http://dx.doi.org/10.3181/0703-RM-59DOI Listing
January 2008

The results in rodent models of atherosclerosis are not interchangeable: the influence of diet and strain.

Atherosclerosis 2007 Dec 24;195(2):e85-92. Epub 2007 Jul 24.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Carrer Sant Joan s/n, 43201-Reus, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2007.06.012DOI Listing
December 2007

Deficiency in monocyte chemoattractant protein-1 modifies lipid and glucose metabolism.

Exp Mol Pathol 2007 Dec 31;83(3):361-6. Epub 2007 Aug 31.

Centre de Recerca Biomèdica, Institut de Recerca en Ciències de la Salut (IRCIS), Hospital Universitari de Sant Joan, C/. Sant Joan s/n, 43201-Reus, Spain.

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http://dx.doi.org/10.1016/j.yexmp.2007.08.003DOI Listing
December 2007

Serum paraoxonase-1 activity and concentration are influenced by human immunodeficiency virus infection.

Atherosclerosis 2007 Sep 30;194(1):175-81. Epub 2006 Aug 30.

Servei de Medicina Interna, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, C. Sant Joan s/n, 43201 Reus, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.07.024DOI Listing
September 2007

Serum paraoxonase-1 in chronic alcoholics: relationship with liver disease.

Clin Biochem 2007 Jun 3;40(9-10):645-50. Epub 2007 Feb 3.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, Reus, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2007.01.020DOI Listing
June 2007

Longitudinal changes in serum paraoxonase-1 activity throughout normal pregnancy.

Clin Chem Lab Med 2006 ;44(7):880-2

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, Reus, Spain.

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http://dx.doi.org/10.1515/CCLM.2006.156DOI Listing
September 2006

Paraoxonase-1 is associated with oxidative stress, fibrosis and FAS expression in chronic liver diseases.

J Hepatol 2006 Jul 6;45(1):51-9. Epub 2006 Feb 6.

DNA Unit, Centre de Diagnòstic Biomèdic, IDIBAPS, Hospital Clínic Universitari,C. Villarroel 170, 08036-Barcelona, Spain.

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http://dx.doi.org/10.1016/j.jhep.2005.12.018DOI Listing
July 2006

Dietary cholesterol and differential monocyte chemoattractant protein-1 gene expression in aorta and liver of apo E-deficient mice.

Biochem Biophys Res Commun 2006 Feb 27;340(4):1078-84. Epub 2005 Dec 27.

Centre de Recerca Biomèdica, Institut de Recerca en Ciències de la Salut (IRCIS), Hospital Universitari de Sant Joan, Calle Sant Joan s/n, 43201-Reus, Spain.

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http://dx.doi.org/10.1016/j.bbrc.2005.12.109DOI Listing
February 2006

The role of circulating monocyte chemoattractant protein-1 as a marker of hepatic inflammation in patients with chronic liver disease.

Clin Biochem 2005 Dec 20;38(12):1138-40. Epub 2005 Oct 20.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, C/. Sant Joan s/n, 43201 Reus, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2005.09.006DOI Listing
December 2005

Genetic association of paraoxonase-1 polymorphisms and chronic hepatitis C virus infection.

Clin Chim Acta 2005 Nov;361(1-2):206-10

DNA Unit, Centre de Diagnòstic Biomèdic, IDIBAPS, Hospital Clínic Universitari, C. Villarroel 170, 08036-Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cccn.2005.05.024DOI Listing
November 2005