Juan-Pablo Casas

Juan-Pablo Casas

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Juan-Pablo Casas

Juan-Pablo Casas

Publications by authors named "Juan-Pablo Casas"

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Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis.

Circ Cardiovasc Genet 2017 Dec;10(6)

From the Post-Graduate Program in Epidemiology, Federal University of Pelotas, Brazil (M.C.B., A.J.D.B., B.L.H., D.F.F., I.O.O.); MRC Integrative Epidemiology Unit (M.C.B., D.L.S.F., T.R.G., D.A.L.) and Population Health Sciences, Bristol Medical School (M.C.B., D.L.S.F., T.R.G., Y.B.-S., D.A.L.), University of Bristol, United Kingdom; Farr Institute of Health Informatics (J.P.C., A.D.H.), Department of Epidemiology and Public Health (M. Kivimaki, M. Kumari), Department of Women's Cancer, Institute for Women's Health, Faculty of Population Health Sciences (U.M., A.G.-M., E.F.), and Institute of Cardiovascular Science (A.D.H.), University College London, United Kingdom; Institute for Social and Economic Research, University of Essex, United Kingdom (M. Kumari); and Department of Physiology and Pharmacology, Institute of Biology, Federal University of Pelotas, Brazil (I.O.O.).

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736126PMC
December 2017

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

Authors:
Amand F Schmidt Daniel I Swerdlow Michael V Holmes Riyaz S Patel Zammy Fairhurst-Hunter Donald M Lyall Fernando Pires Hartwig Bernardo Lessa Horta Elina Hyppönen Christine Power Max Moldovan Erik van Iperen G Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Tian Liu Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Lise Lotte Nystrup Husemoen Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Kenneth Starup Simonsen Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty H Lester Kirchner Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen Dennis O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Daniel J Smith Tom Meade Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Beverley Balkau Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Paul M Ridker Daniel I Chasman Alex P Reiner Leslie A Lange Marylyn D Ritchie Folkert W Asselbergs Juan-Pablo Casas Brendan J Keating David Preiss Aroon D Hingorani Naveed Sattar

Lancet Diabetes Endocrinol 2017 02 29;5(2):97-105. Epub 2016 Nov 29.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30396-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266795PMC
February 2017

Efficacy and safety of ablation for people with non-paroxysmal atrial fibrillation.

Cochrane Database Syst Rev 2016 11 22;11:CD012088. Epub 2016 Nov 22.

Institute of Health Informatics, University College London, 222 Euston Road, London, UK, NW1 2DA.

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http://dx.doi.org/10.1002/14651858.CD012088.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464287PMC
November 2016

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.

Circ Cardiovasc Genet 2016 Jun 25;9(3):231-9. Epub 2016 Apr 25.

From the MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol (F.D., G.D.S., M.A.-K., D.A.L., T.R.G., N.J.T.); Institute of Cardiovascular Science, University College London, London, United Kingdom (F.D., C.D., J.-P.C.); Computational Medicine, Faculty of Medicine, University of Oulu & Biocenter Oulu, Oulu (M.A.-K., J.K., P.W., P.S., A.J.K.); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio (M.A.-K., J.K., P.S.); Public Health Genomics Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland (J.K.); and Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom (C.D., J.-P.C.).

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http://dx.doi.org/10.1161/CIRCGENETICS.115.001302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920206PMC
June 2016

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase.

J Am Coll Cardiol 2016 Mar;67(10):1200-1210

Computational Medicine, Institute of Health Sciences, University of Oulu and Biocenter Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland; Oulu University Hospital, Oulu, Finland; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom; Computational Medicine, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.12.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783625PMC
March 2016

A qualitative geographical information systems approach to explore how older people over 70 years interact with and define their neighbourhood environment.

Health Place 2015 Nov 27;36:127-33. Epub 2015 Oct 27.

Department of Health Services Research and Policy, Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.healthplace.2015.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676086PMC
November 2015

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts.

Circulation 2015 Mar 8;131(9):774-85. Epub 2015 Jan 8.

From Computational Medicine, Institute of Health Sciences, University of Oulu, Finland (P.W., P.S., T. Tynkkynen, Q.W., M.T., A.J.K., J. Kettunen, M.A.-K.); Department of Chronic Disease Prevention, National Institute for Health and Welfare, Finland (P.W., A.S.H., J. Kettunen, A.J., M.P., V.S.); Institute for Molecular Medicine Finland, University of Helsinki (P.W., A.S.H., M.P., S.P.); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio (P.S., T. Tynkkynen, Q.W., M.T., M.A.-K.); Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, United Kingdom (D.P.-M., J.-P.C.); Institute of Cardiovascular Science, University College London, United Kingdom (T. Tillin, A.D.H., J.-P.C., N.C.); Framingham Heart Study of the National Heart, Lung, and Blood Institute and Boston University School of Medicine, Framingham, MA (A.G., R.S.V.); Genome Analysis Center, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg, Germany (A.A., J.A.); Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (J. Kaikkonen, V.M., O.T.R.); Department of Food and Environmental Sciences, University of Helsinki, Finland (V.M.,); Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Finland (M.K.); Department of Clinical Chemistry, Fimlab Laboratories, and School of Medicine, University of Tampere, Finland (T.L.); Medical Research Council Integrative Epidemiology Unit at the University of Bristol, United Kingdom (D.A.L., T.R.G., M.A.-K.); School of Social and Community Medicine, University of Bristol, United Kingdom (D.A.L., T.R.G., M.A.-K.); Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (N.S.); Hannover Medical School, Hannover Unified Biobank, Germany (T.I.); Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351161PMC
March 2015

The cochrane heart at global heart.

Glob Heart 2014 Dec;9(4):511

Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gheart.2014.12.003DOI Listing
December 2014

Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores.

Genet Epidemiol 2014 Jan 23;38(1):72-83. Epub 2013 Nov 23.

Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.1002/gepi.21777DOI Listing
January 2014

Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials.

Br J Clin Pharmacol 2013 Nov;76(5):649-67

Genetic Epidemiology Group, Department of Epidemiology & Public Health, Division of Population Health, University College London, London, WC1E 6BT, UK; Department of Pharmacy, Royal National Orthopaedic Hospital, Middlesex, HA7 4LP, UK.

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http://dx.doi.org/10.1111/bcp.12083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853525PMC
November 2013

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thromb Haemost 2013 Nov 29;110(5):995-1003. Epub 2013 Aug 29.

MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1160/TH13-02-0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067543PMC
November 2013

Oxygen therapy in acute myocardial infarction – good or bad?

Cochrane Database Syst Rev 2013 Aug 21(8):ED000065. Epub 2013 Aug 21.

The Heart Hospital, University College London Hospitals UCLH, London, UK.

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http://dx.doi.org/10.1002/14651858.ED000065DOI Listing
August 2013

A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array.

Eur J Hum Genet 2013 Jul 28;21(7):779-83. Epub 2012 Nov 28.

MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield Grove, Bristol, UK.

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http://dx.doi.org/10.1038/ejhg.2012.242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682876PMC
July 2013

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Authors:
Daniel I Swerdlow Michael V Holmes Karoline B Kuchenbaecker Jorgen E L Engmann Tina Shah Reecha Sofat Yiran Guo Christina Chung Anne Peasey Roman Pfister Simon P Mooijaart Helen A Ireland Maarten Leusink Claudia Langenberg Ka Wah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos John Hardy Michael A Nalls Yun Rose Li Gordon Lowe Marlene Stewart Suzette J Bielinski Julian Peto Nicholas J Timpson John Gallacher Malcolm Dunlop Richard Houlston Ian Tomlinson Ioanna Tzoulaki Jian'an Luan Jolanda M A Boer Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Luigi Ferrucci Stefania Bandenelli Toshiko Tanaka James F Meschia Andrew Singleton Gerjan Navis Irene Mateo Leach Stephan J L Bakker Ron T Gansevoort Ian Ford Stephen E Epstein Mary Susan Burnett Joe M Devaney J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Yolanda van der Graaf Pim A de Jong Anke-Hilse Mailand-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Jeffrey W Stephens Charles B Eaton Jennifer G Robinson JoAnn E Manson F Gerry Fowkes Timonthy M Frayling Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Susan Redline Leslie A Lange Meena Kumari Nick J Wareham W M Monique Verschuren Emelia J Benjamin John C Whittaker Anders Hamsten Frank Dudbridge J A Chris Delaney Andrew Wong Diana Kuh Rebecca Hardy Berta Almoguera Castillo John J Connolly Pim van der Harst Eric J Brunner Michael G Marmot Christina L Wassel Steve E Humphries Philippa J Talmud Mika Kivimaki Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Hakon Hakonarson Alex P Reiner Brendan J Keating Naveed Sattar Aroon D Hingorani Juan Pablo Casas

Lancet 2012 Mar 14;379(9822):1214-24. Epub 2012 Mar 14.

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http://dx.doi.org/10.1016/S0140-6736(12)60110-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316968PMC
March 2012

Blood pressure loci identified with a gene-centric array.

Authors:
Toby Johnson Tom R Gaunt Stephen J Newhouse Sandosh Padmanabhan Maciej Tomaszewski Meena Kumari Richard W Morris Ioanna Tzoulaki Eoin T O'Brien Neil R Poulter Peter Sever Denis C Shields Simon Thom Sasiwarang G Wannamethee Peter H Whincup Morris J Brown John M Connell Richard J Dobson Philip J Howard Charles A Mein Abiodun Onipinla Sue Shaw-Hawkins Yun Zhang George Davey Smith Ian N M Day Debbie A Lawlor Alison H Goodall F Gerald Fowkes Gonçalo R Abecasis Paul Elliott Vesela Gateva Peter S Braund Paul R Burton Christopher P Nelson Martin D Tobin Pim van der Harst Nicola Glorioso Hani Neuvrith Erika Salvi Jan A Staessen Andrea Stucchi Nabila Devos Xavier Jeunemaitre Pierre-François Plouin Jean Tichet Peeter Juhanson Elin Org Margus Putku Siim Sõber Gudrun Veldre Margus Viigimaa Anna Levinsson Annika Rosengren Dag S Thelle Claire E Hastie Thomas Hedner Wai K Lee Olle Melander Björn Wahlstrand Rebecca Hardy Andrew Wong Jackie A Cooper Jutta Palmen Li Chen Alexandre F R Stewart George A Wells Harm-Jan Westra Marcel G M Wolfs Robert Clarke Maria Grazia Franzosi Anuj Goel Anders Hamsten Mark Lathrop John F Peden Udo Seedorf Hugh Watkins Willem H Ouwehand Jennifer Sambrook Jonathan Stephens Juan-Pablo Casas Fotios Drenos Michael V Holmes Mika Kivimaki Sonia Shah Tina Shah Philippa J Talmud John Whittaker Chris Wallace Christian Delles Maris Laan Diana Kuh Steve E Humphries Fredrik Nyberg Daniele Cusi Robert Roberts Christopher Newton-Cheh Lude Franke Alice V Stanton Anna F Dominiczak Martin Farrall Aroon D Hingorani Nilesh J Samani Mark J Caulfield Patricia B Munroe

Am J Hum Genet 2011 Dec 17;89(6):688-700. Epub 2011 Nov 17.

Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.

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http://dx.doi.org/10.1016/j.ajhg.2011.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234370PMC
December 2011

Statins for the primary prevention of cardiovascular disease.

Cochrane Database Syst Rev 2011 Jan 19(1):CD004816. Epub 2011 Jan 19.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK, WC1E 7HT.

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http://dx.doi.org/10.1002/14651858.CD004816.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164175PMC
January 2011

Telemonitoring for chronic heart failure: not ready for prime time.

Cochrane Database Syst Rev 2010 Aug 9;2011:ED000008. Epub 2010 Aug 9.

Cochrane Heart Group.

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http://dx.doi.org/10.1002/14651858.ED000008DOI Listing
August 2010

[Normal lung volumes in patients with idiopathic pulmonary fibrosis and emphysema].

Medicina (B Aires) 2008 ;68(4):282-4

Servicio de Neumonología, Hospital Privado Centro Médico de Córdoba.

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July 2009

Ischaemic stroke subtypes and their genetic basis: a comprehensive meta-analysis of small and large vessel stroke.

Eur Neurol 2009 28;61(2):76-86. Epub 2008 Nov 28.

Imperial College Cerebrovascular Research Unit, Department of Clinical Neuroscience, Imperial College London & Hammersmith Hospitals, London, UK.

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https://www.karger.com/Article/FullText/177939
Publisher Site
http://dx.doi.org/10.1159/000177939DOI Listing
April 2009

The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults.

PLoS One 2008 14;3(11):e3691. Epub 2008 Nov 14.

Imperial College Cerebrovascular Research Unit (ICCRU), Department of Clinical Neuroscience, Imperial College London & Hammersmith Hospitals, London, UK.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003691PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579487PMC
February 2009

Relation between the global burden of disease and randomized clinical trials conducted in Latin America published in the five leading medical journals.

PLoS One 2008 Feb 27;3(2):e1696. Epub 2008 Feb 27.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001696PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246037PMC
February 2008

[Lung volume reduction surgery for emphysema. Long term results].

Medicina (B Aires) 2002 ;62(2):115-23

Servicio de Neumonología, Hospital Privado Córdoba, Calle Naciones Unidas 346, 5016 Córdoba, Argentina.

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June 2002