Juan Sainz

Juan Sainz

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Juan Sainz

Juan Sainz

Publications by authors named "Juan Sainz"

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Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma.

Leukemia 2019 Sep 9;33(9):2324-2330. Epub 2019 Apr 9.

ProfilExpert, Lyon, France.

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http://dx.doi.org/10.1038/s41375-019-0452-6DOI Listing
September 2019

Trends in survival of multiple myeloma: a thirty-year population-based study in a single institution.

Cancer Epidemiol 2015 Oct 12;39(5):693-9. Epub 2015 Aug 12.

Monoclonal Gammopathies Unit, University Hospital Virgen de las Nieves, Granada, Spain; Department of Hematology, University Hospital Virgen de las Nieves, Granada, Spain; Genomic Oncology Area, GENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS, Granada, Spain; Instituto de Investigación Biosanitaria de Granada (Ibs.GRANADA), Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.

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http://dx.doi.org/10.1016/j.canep.2015.08.002DOI Listing
October 2015

Genetic variants within immune-modulating genes influence the risk of developing rheumatoid arthritis and anti-TNF drug response: a two-stage case-control study.

Pharmacogenet Genomics 2015 Sep;25(9):432-43

aGenomic Oncology Area bArea of Genomic Medicine, GENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government Departments of cRheumatology dImmunology, Virgen de las Nieves University Hospital, Granada eDepartment of Rheumatology, Reina Sofía Hospital/Maimónides Institut for Biomedical Research of CórdobaI (IMIBIC)/University of Córdoba, Córdoba fRheumatology Unit, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain gRheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa hDepartment of Rheumatology, Santa Maria Hospital-CHLN, Lisbon, Portugal iRheumatology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

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http://dx.doi.org/10.1097/FPC.0000000000000155DOI Listing
September 2015

Transplantation-Associated Thrombotic Microangiopathy in Patients Treated With Sirolimus and Cyclosporine as Salvage Therapy for Graft-Versus-Host Disease.

Ann Pharmacother 2015 Sep 9;49(9):986-94. Epub 2015 Jul 9.

Department of Hematology, Hospital Universitario Virgen de las Nieves, Granada, Spain Genyo, Pfizer-University of Granada-Junta de Andalucía, Granada, Spain.

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http://dx.doi.org/10.1177/1060028015593369DOI Listing
September 2015

Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium.

Endocr Relat Cancer 2015 Aug 22;22(4):545-59. Epub 2015 Jun 22.

Genomic Oncology AreaGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS, Granada, 18016 Granada, SpainHematology DepartmentVirgen de las Nieves University Hospital, Granada, SpainGenomic Epidemiology GroupGerman Cancer Research Center (DKFZ), Heidelberg, GermanyDepartment of BiologyUniversity of Pisa, Pisa, ItalyDepartment of HematologyHospital Universitario Doce de Octubre, Madrid, SpainArea of Genomic MedicineGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Granada, SpainSemmelweis UniversityBudapest, HungaryHaematology DepartmentUniversity Hospital of Salamanca and IBSAL, Salamanca, SpainMedical University of LodzLodz, PolandINSERM UMR 1052/CNRS 5286Université Claude Bernard Lyon I, Lyon, FranceMorales Meseguer General University HospitalMurcia, SpainHaematoloy ClinikHolly Cross Cancer Center, Kielce, PolandINSERMU900, Genetic Epidemiology of Cancers team, Institut Curie, Mines ParisTech, Paris, FranceLife and Health Sciences Research Institute (ICVS)School of Health Sciences, University of Minho, Braga, PortugalICVS/3B's - PT Government Associate LaboratoryBraga/Guimarães, PortugalMolecular Oncology Research CenterBarretos Cancer Hospital, Barretos, BrazilIDIBELL - Catalan Institute of OncologyUniversity of Barcelona, Barcelona 08907, SpainDepartment of HematologyCracow University Hospital, Cracow, PolandOrgan CenterHospital of Southern Jutland, DK-6200 Aabenraa, DenmarkFaculty of Health SciencesInstitute of Regional Health Research, University of Southern Denmark, DK-5000 Odense C, DenmarkUO HematologyDepartment of Internal and Experimental Medicine, University of Pisa, Pisa, ItalyClinic of Biochemistry and ImmunologyLaboratory Center, Hospital of Southern Jutland, Aabenraa, DenmarkDepartment of HaematologyRigshospitalet and Roskilde Hospital, Copenhagen University, Copenhagen, Denmark Genomic Oncology AreaGENYO, Cen

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http://dx.doi.org/10.1530/ERC-15-0029DOI Listing
August 2015

Genetic variants within the TNFRSF1B gene and susceptibility to rheumatoid arthritis and response to anti-TNF drugs: a multicenter study.

Pharmacogenet Genomics 2015 Jul;25(7):323-33

aGenomic Oncology Area, GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada Departments of bImmunology cRheumatology, Virgen de las Nieves University Hospital, Granada dRheumatology Department, Reina Sofía Hospital, IMIBIC, University of Córdoba, Córdoba eRheumatology Unit, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain fRheumatology Research Unit, Molecular Medicine Institute, Medicine Faculty of Lisbon University gRheumatology Department, Santa Maria Hospital - CHLN, Lisbon, Portugal hRheumatology Department, University of Medicine and Pharmacy 'Iuliu Hatieganu' Cluj-Napoca, Romania.

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http://dx.doi.org/10.1097/FPC.0000000000000140DOI Listing
July 2015

GWAS-identified common variants for obesity are not associated with the risk of developing colorectal cancer.

Cancer Epidemiol Biomarkers Prev 2014 Jun 24;23(6):1125-8. Epub 2014 Mar 24.

Authors' Affiliations: Division of Molecular Genetic Epidemiology, Division of Clinical Epidemiology and Aging Research, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany; and Center for Primary Health Care Research, Clinical Research Center, Lund University, Malmö, SwedenAuthors' Affiliations: Division of Molecular Genetic Epidemiology, Division of Clinical Epidemiology and Aging Research, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany; and Center for Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden

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http://dx.doi.org/10.1158/1055-9965.EPI-13-1354DOI Listing
June 2014

Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.

Cancer Epidemiol Biomarkers Prev 2014 Apr 12;23(4):670-4. Epub 2014 Feb 12.

Authors' Affiliations: Genomic Epidemiology Group, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Hematology, Cracow University Hospital, Cracow; Medical University of Łodz; Laboratory of Clinical and Transplant Immunology and Genetics, Copernicus Memorial Hospital, Łodz; Rzeszow Regional Hospital, Rzeszow; Holycross Cancer Center, Kielce, Poland; Department of Hematology, Hospital Universitario Doce de Octubre, Madrid; Morales Meseguer General University Hospital, Murcia; University Hospital of Salamanca, Salamanca; Genomic Oncology Area, GENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government; Hematology Department, Virgen de las Nieves University Hospital, Granada; IDIBELL-Catalan Institute of Oncology, University of Barcelona, Barcelona, Spain; Semmelweis University, Budapest, Hungary; Institut National de la Santé et de la Recherche Medicale (INSERM) UMR 1052/CNRS 5286, Université Claude Bernard Lyon I, Lyon; Genetic Epidemiology of Cancer team, INSERM, U900, Institut Curie, Mines ParisTech, Paris, France; Department of Biology, University of Pisa, Pisa, Italy; Clinic of Immunology, Laboratory Center, Hospital of Southern Jutland, Sønderborg; Organ Center, Hospital of Southern Jutland, Aabenraa; Institute of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense C; National Research Centre for the Working Environment, Copenhagen; Roskilde Hospital, Copenhagen University, Roskilde, Denmark; Life and Health Sciences Research Institute, University of Minho, Braga; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal; UO Hematology, Department of Internal and Experimental Medicine, University of Pisa, Pisa, Italy; and Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-1115DOI Listing
April 2014

Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome.

Int J Cancer 2013 Nov 29;133(10):2325-33. Epub 2013 May 29.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.28251DOI Listing
November 2013

Dectin-1 and DC-SIGN polymorphisms associated with invasive pulmonary Aspergillosis infection.

PLoS One 2012 27;7(2):e32273. Epub 2012 Feb 27.

Genomic Oncology Area, Genyo, Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research, Granada, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032273PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288082PMC
August 2012

Genome-wide gene expression analysis in mouse embryonic stem cells.

Int J Dev Biol 2011 ;55(10-12):995-1006

Genomic Oncology Area, GENYO (Pfizer-University of Granada-Andalusian Goverment Centre for Genomics and Oncological Research), Granada, Spain.

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http://dx.doi.org/10.1387/ijdb.103123jsDOI Listing
May 2012

Effect of type 2 diabetes predisposing genetic variants on colorectal cancer risk.

J Clin Endocrinol Metab 2012 May 14;97(5):E845-51. Epub 2012 Mar 14.

Division of Molecular Genetic Epidemiology, German Cancer Research Center, D-69120 Heidelberg, Germany.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2011-2565DOI Listing
May 2012

Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes.

Endocr Relat Cancer 2011 Jun 8;18(3):371-84. Epub 2011 Jun 8.

Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120 Heidelberg, Germany.

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http://erc.endocrinology-journals.org/cgi/doi/10.1530/ERC-11
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http://dx.doi.org/10.1530/ERC-11-0057DOI Listing
June 2011

Interleukin-10 promoter polymorphism as risk factor to develop invasive pulmonary aspergillosis.

Immunol Lett 2007 Mar 8;109(1):76-82. Epub 2007 Feb 8.

Unidad de Investigación, Servicio de Hematología, Hospital Universitario Virgen de las Nieves, Centro Regional de Transfusión Sanguínea Granada-Almería, Edificio Licinio de la Fuente-Planta Sótano, Dr. Azpitarte, 4, 18012 Granada, Spain.

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http://dx.doi.org/10.1016/j.imlet.2007.01.005DOI Listing
March 2007

Variable number of tandem repeats of TNF receptor type 2 promoter as genetic biomarker of susceptibility to develop invasive pulmonary aspergillosis.

Hum Immunol 2007 Jan 16;68(1):41-50. Epub 2006 Nov 16.

Unidad de Investigación, Servicio de Hematología, Hospital Universitario Virgen de las Nieves, Granada, Spain.

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http://dx.doi.org/10.1016/j.humimm.2006.10.011DOI Listing
January 2007

Penaeus vannamei isotrypsins: purification and characterization.

Comp Biochem Physiol B Biochem Mol Biol 2004 Jun;138(2):155-62

Laboratorio de Bioquímica, Centro de Investigaciones Biológicas del Noroeste. Mar Bermejo No. 195, Col. Playa Palo de Santa Rita, La Paz B.C.S. 23090, Mexico.

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http://dx.doi.org/10.1016/j.cbpc.2004.03.002DOI Listing
June 2004

Gender difference in the role of endothelium-derived relaxing factors modulating renal vascular reactivity.

Eur J Pharmacol 2004 Feb;486(3):281-8

Departamento de Fisiología, Facultad de Medicina, Servicio de Nefrología, Unidad Experimental, E-18012 Granada, Spain.

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http://dx.doi.org/10.1016/j.ejphar.2003.12.036DOI Listing
February 2004

Increased pressor sensitivity to chronic nitric oxide deficiency in hyperthyroid rats.

Hypertension 2003 Aug 23;42(2):220-5. Epub 2003 Jun 23.

Departamento de Fisiología, Facultad de Medicina, E-18012 Granada, Spain.

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http://dx.doi.org/10.1161/01.HYP.0000081944.47230.69DOI Listing
August 2003

Role of endothelium-derived relaxing factors in the renal response to vasoactive agents in hypothyroid rats.

Am J Physiol Endocrinol Metab 2003 Jul 25;285(1):E182-8. Epub 2003 Mar 25.

Departamento de Fisiología, Facultad de Medicina, Hospital Virgen de las Nieves, Granada, Spain.

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http://dx.doi.org/10.1152/ajpendo.00558.2002DOI Listing
July 2003

Chronic blockade of neuronal nitric oxide synthase does not affect long-term control of blood pressure in normal, saline-drinking or deoxycorticosterone-treated rats.

Exp Physiol 2003 Mar;88(2):243-50

Departamento de Fisiología, Facultad de Medicina, Servicio de Nefrología, Unidad Experimental, Hospital Virgen de las Nieves, Granada, Spain.

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March 2003

Nitric oxide synthase activity in hyperthyroid and hypothyroid rats.

Eur J Endocrinol 2002 Jul;147(1):117-22

Departamento de Fisiología de la Facultad de Medicina de Granada, Granada, Spain.

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http://dx.doi.org/10.1530/eje.0.1470117DOI Listing
July 2002

Role of endothelium-derived relaxing factors in adrenomedullin-induced vasodilation in the rat kidney.

Eur J Pharmacol 2002 May;444(1-2):97-102

Departamento de Fisiologi;a, Facultad de Medicina, Unidad de Nefrologi;a Experimental, Hospital Virgen de las Nieves, E-18012, Granada, Spain.

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http://dx.doi.org/10.1016/s0014-2999(02)01605-9DOI Listing
May 2002