Juan R Cubillos-Ruiz

Juan R Cubillos-Ruiz

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Juan R Cubillos-Ruiz

Juan R Cubillos-Ruiz

Publications by authors named "Juan R Cubillos-Ruiz"

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36Publications

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Dendritic Cell Metabolism and Function in Tumors.

Authors:
Paolo Giovanelli Tito A Sandoval Juan R Cubillos-Ruiz

Trends Immunol 2019 Aug 10;40(8):699-718. Epub 2019 Jul 10.

Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.06.004DOI Listing
August 2019

Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.

Authors:
Yu Cao Jimena Trillo-Tinoco Rosa A Sierra Carmen Anadon Wenjie Dai Eslam Mohamed Ling Cen Tara L Costich Anthony Magliocco Douglas Marchion Richard Klar Sven Michel Frank Jaschinski Richard R Reich Shikhar Mehrotra Juan R Cubillos-Ruiz David H Munn Jose R Conejo-Garcia Paulo C Rodriguez

Nat Commun 2019 Aug 15;10(1):3680. Epub 2019 Aug 15.

Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1038/s41467-019-11563-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695448PMC
August 2019

Somatic mutations and cell identity linked by Genotyping of Transcriptomes.

Authors:
Anna S Nam Kyu-Tae Kim Ronan Chaligne Franco Izzo Chelston Ang Justin Taylor Robert M Myers Ghaith Abu-Zeinah Ryan Brand Nathaniel D Omans Alicia Alonso Caroline Sheridan Marisa Mariani Xiaoguang Dai Eoghan Harrington Alessandro Pastore Juan R Cubillos-Ruiz Wayne Tam Ronald Hoffman Raul Rabadan Joseph M Scandura Omar Abdel-Wahab Peter Smibert Dan A Landau

Nature 2019 07 3;571(7765):355-360. Epub 2019 Jul 3.

New York Genome Center, New York, NY, USA.

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http://www.nature.com/articles/s41586-019-1367-0
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http://dx.doi.org/10.1038/s41586-019-1367-0DOI Listing
July 2019

IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.

Authors:
Sahil Chopra Paolo Giovanelli Perla Abigail Alvarado-Vazquez Sara Alonso Minkyung Song Tito A Sandoval Chang-Suk Chae Chen Tan Miriam M Fonseca Silvia Gutierrez Leandro Jimenez Kotha Subbaramaiah Takao Iwawaki Philip J Kingsley Lawrence J Marnett Andrew V Kossenkov Mariano Sanchez Crespo Andrew J Dannenberg Laurie H Glimcher E Alfonso Romero-Sandoval Juan R Cubillos-Ruiz

Science 2019 07;365(6450)

Weill Cornell Graduate School of Medical Sciences, Cornell University. New York, NY 10065, USA.

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http://dx.doi.org/10.1126/science.aau6499DOI Listing
July 2019

Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns.

Authors:
Saioa Márquez José Javier Fernández Cristina Mancebo Carmen Herrero-Sánchez Sara Alonso Tito A Sandoval Macarena Rodríguez Prados Juan R Cubillos-Ruiz Olimpio Montero Nieves Fernández Mariano Sánchez Crespo

Cell Rep 2019 Apr;27(2):525-536.e4

Instituto de Biología y Genética Molecular, CSIC-Universidad de Valladolid, 47003 Valladolid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193034
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http://dx.doi.org/10.1016/j.celrep.2019.03.033DOI Listing
April 2019

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.

Authors:
Yu Cao Jimena Trillo-Tinoco Rosa A Sierra Carmen Anadon Wenjie Dai Eslam Mohamed Ling Cen Tara L Costich Anthony Magliocco Douglas Marchion Richard Klar Sven Michel Frank Jaschinski Richard R Reich Shikhar Mehrotra Juan R Cubillos-Ruiz David H Munn Jose R Conejo-Garcia Paulo C Rodriguez

Nat Commun 2019 03 20;10(1):1280. Epub 2019 Mar 20.

Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1038/s41467-019-09263-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426975PMC
March 2019

Endoplasmic Reticulum Stress Responses in Intratumoral Immune Cells: Implications for Cancer Immunotherapy.

Authors:
Minkyung Song Juan R Cubillos-Ruiz

Trends Immunol 2019 02 3;40(2):128-141. Epub 2019 Jan 3.

Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714906183022
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http://dx.doi.org/10.1016/j.it.2018.12.001DOI Listing
February 2019

PolyGlcNAc-containing exopolymers enable surface penetration by non-motile Enterococcus faecalis.

Authors:
Yusibeska Ramos Jorge Rocha Ana L Hael Jordi van Gestel Hera Vlamakis Colette Cywes-Bentley Juan R Cubillos-Ruiz Gerald B Pier Michael S Gilmore Roberto Kolter Diana K Morales

PLoS Pathog 2019 02 11;15(2):e1007571. Epub 2019 Feb 11.

Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386517PMC
February 2019

IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity.

Authors:
Minkyung Song Tito A Sandoval Chang-Suk Chae Sahil Chopra Chen Tan Melanie R Rutkowski Mahesh Raundhal Ricardo A Chaurio Kyle K Payne Csaba Konrad Sarah E Bettigole Hee Rae Shin Michael J P Crowley Juan P Cerliani Andrew V Kossenkov Ievgen Motorykin Sheng Zhang Giovanni Manfredi Dmitriy Zamarin Kevin Holcomb Paulo C Rodriguez Gabriel A Rabinovich Jose R Conejo-Garcia Laurie H Glimcher Juan R Cubillos-Ruiz

Nature 2018 10 10;562(7727):423-428. Epub 2018 Oct 10.

Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.

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http://www.nature.com/articles/s41586-018-0597-x
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http://dx.doi.org/10.1038/s41586-018-0597-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237282PMC
October 2018

Unfolding anti-tumor immunity: ER stress responses sculpt tolerogenic myeloid cells in cancer.

Authors:
Juan R Cubillos-Ruiz Eslam Mohamed Paulo C Rodriguez

J Immunother Cancer 2017 17;5. Epub 2017 Jan 17.

Department of Medicine, Georgia Cancer Center, Augusta University, 1410 Laney Walker Blvd, Room CN-4114, Augusta, GA 30912 USA.

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http://dx.doi.org/10.1186/s40425-016-0203-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240216PMC
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.

Authors:
Haiying Zhang Daniela Freitas Han Sang Kim Kristina Fabijanic Zhong Li Haiyan Chen Milica Tesic Mark Henrik Molina Alberto Benito Martin Linda Bojmar Justin Fang Sham Rampersaud Ayuko Hoshino Irina Matei Candia M Kenific Miho Nakajima Anders Peter Mutvei Pasquale Sansone Weston Buehring Huajuan Wang Juan Pablo Jimenez Leona Cohen-Gould Navid Paknejad Matthew Brendel Katia Manova-Todorova Ana Magalhães José Alexandre Ferreira Hugo Osório André M Silva Ashish Massey Juan R Cubillos-Ruiz Giuseppe Galletti Paraskevi Giannakakou Ana Maria Cuervo John Blenis Robert Schwartz Mary Sue Brady Héctor Peinado Jacqueline Bromberg Hiroshi Matsui Celso A Reis David Lyden

Nat Cell Biol 2018 03 19;20(3):332-343. Epub 2018 Feb 19.

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.

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http://www.nature.com/articles/s41556-018-0040-4
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http://dx.doi.org/10.1038/s41556-018-0040-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931706PMC
March 2018

Dendritic cell rehab: new strategies to unleash therapeutic immunity in ovarian cancer.

Authors:
Chang-Suk Chae Eli Teran-Cabanillas Juan R Cubillos-Ruiz

Cancer Immunol Immunother 2017 Aug 18;66(8):969-977. Epub 2017 Feb 18.

Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, USA.

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http://dx.doi.org/10.1007/s00262-017-1958-2DOI Listing
August 2017

Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells.

Authors:
Saioa Márquez José Javier Fernández Eli Terán-Cabanillas Carmen Herrero Sara Alonso Alicia Azogil Olimpio Montero Takao Iwawaki Juan R Cubillos-Ruiz Nieves Fernández Mariano Sánchez Crespo

Front Immunol 2017 19;8:639. Epub 2017 Jun 19.

Instituto de Biología y Genética Molecular, CSIC-Universidad de Valladolid, Valladolid, Spain.

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http://dx.doi.org/10.3389/fimmu.2017.00639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475432PMC
June 2017

Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer.

Authors:
Juan R Cubillos-Ruiz Sarah E Bettigole Laurie H Glimcher

Cell 2017 02;168(4):692-706

Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02215, USA; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333759PMC
February 2017

State-of-the-art of regulatory dendritic cells in cancer.

Authors:
Jose R Conejo-Garcia Melanie R Rutkowski Juan R Cubillos-Ruiz

Pharmacol Ther 2016 08 23;164:97-104. Epub 2016 Apr 23.

Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.pharmthera.2016.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942379PMC
August 2016

Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment.

Authors:
Juan R Cubillos-Ruiz Sarah E Bettigole Laurie H Glimcher

Clin Cancer Res 2016 05 15;22(9):2121-6. Epub 2016 Mar 15.

Sandra and Edward Meyer Cancer Center, Weill Cornell Medical College, New York, New York. Department of Medicine, Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854763PMC
May 2016

Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy.

Authors:
Juan R Cubillos-Ruiz Laurie H Glimcher

Oncoimmunology 2016 Mar 29;5(3):e1098802. Epub 2015 Oct 29.

Sandra and Edward Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1080/2162402X.2015.1098802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839339PMC
March 2016

ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis.

Authors:
Juan R Cubillos-Ruiz Pedro C Silberman Melanie R Rutkowski Sahil Chopra Alfredo Perales-Puchalt Minkyung Song Sheng Zhang Sarah E Bettigole Divya Gupta Kevin Holcomb Lora H Ellenson Thomas Caputo Ann-Hwee Lee Jose R Conejo-Garcia Laurie H Glimcher

Cell 2015 Jun 11;161(7):1527-38. Epub 2015 Jun 11.

Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674150057
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http://dx.doi.org/10.1016/j.cell.2015.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580135PMC
June 2015

IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.

Authors:
Stanley Adoro Juan R Cubillos-Ruiz Xi Chen Maud Deruaz Vladimir D Vrbanac Minkyung Song Suna Park Thomas T Murooka Timothy E Dudek Andrew D Luster Andrew M Tager Hendrik Streeck Brittany Bowman Bruce D Walker Douglas S Kwon Vanja Lazarevic Laurie H Glimcher

Nat Commun 2015 Jun 25;6:7562. Epub 2015 Jun 25.

Department of Medicine, Weill Cornell Medical College, Cornell University, 1300 York Avenue, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/ncomms8562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481879PMC
June 2015

Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment.

Authors:
Jason R Baird Barbara A Fox Kiah L Sanders Patrick H Lizotte Juan R Cubillos-Ruiz Uciane K Scarlett Melanie R Rutkowski Jose R Conejo-Garcia Steven Fiering David J Bzik

Cancer Res 2013 Jul 23;73(13):3842-51. Epub 2013 May 23.

Department of Microbiology and Immunology, The Geisel School of Medicine at Dartmouth, Norris Cotton Cancer Center, Lebanon, New Hampshire 03756, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702636PMC
July 2013

Reprogramming immune responses via microRNA modulation.

Authors:
Juan R Cubillos-Ruiz Melanie R Rutkowski Julia Tchou Jose R Conejo-Garcia

Microrna Diagn Ther 2013 Apr;1(1)

Tumor Microenvironment and Metastasis Program, The Wistar Institute, 3601 Spruce St, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.2478/micrnat-2013-0001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183223PMC
April 2013

Good things come in small packages: Therapeutic anti-tumor immunity induced by microRNA nanoparticles.

Authors:
Juan R Cubillos-Ruiz Lorenzo F Sempere Jose R Conejo-Garcia

Oncoimmunology 2012 Sep;1(6):968-970

Department of Medicine; Weill Cornell Medical College; New York, NY USA ; The Ragon Institute of MGH; MIT and Harvard; Charlestown, MA USA.

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http://dx.doi.org/10.4161/onci.20020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489762PMC
September 2012

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.

Authors:
Diego A Rodriguez Sebastian Zamorano Fernanda Lisbona Diego Rojas-Rivera Hery Urra Juan R Cubillos-Ruiz Ricardo Armisen Daniel R Henriquez Emily H Cheng Michal Letek Tomas Vaisar Thergiory Irrazabal Christian Gonzalez-Billault Anthony Letai Felipe X Pimentel-Muiños Guido Kroemer Claudio Hetz

EMBO J 2012 May 17;31(10):2322-35. Epub 2012 Apr 17.

Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, Santiago, Chile.

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http://dx.doi.org/10.1038/emboj.2012.84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364744PMC
May 2012

Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer.

Authors:
Juan R Cubillos-Ruiz Jason R Baird Amelia J Tesone Melanie R Rutkowski Uciane K Scarlett Ana L Camposeco-Jacobs Jorge Anadon-Arnillas Noah M Harwood Murray Korc Steven N Fiering Lorenzo F Sempere Jose R Conejo-Garcia

Cancer Res 2012 Apr 3;72(7):1683-93. Epub 2012 Feb 3.

Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, New Hampshire, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319850PMC
April 2012

Ovarian cancer progression is controlled by phenotypic changes in dendritic cells.

Authors:
Uciane K Scarlett Melanie R Rutkowski Adam M Rauwerdink Jennifer Fields Ximena Escovar-Fadul Jason Baird Juan R Cubillos-Ruiz Ana C Jacobs Jorge L Gonzalez John Weaver Steven Fiering Jose R Conejo-Garcia

J Exp Med 2012 Mar 20;209(3):495-506. Epub 2012 Feb 20.

Immunology Program, the Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1084/jem.20111413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302234PMC
March 2012

It never rains but it pours: potential role of butyrophilins in inhibiting anti-tumor immune responses.

Authors:
Juan R Cubillos-Ruiz Jose R Conejo-Garcia

Cell Cycle 2011 Feb 1;10(3):368-9. Epub 2011 Feb 1.

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http://www.tandfonline.com/doi/abs/10.4161/cc.10.3.14565
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115012PMC
http://dx.doi.org/10.4161/cc.10.3.14565DOI Listing
February 2011

Antifungal mechanisms by which a novel Pseudomonas aeruginosa phenazine toxin kills Candida albicans in biofilms.

Authors:
Diana K Morales Nicholas J Jacobs Sathish Rajamani Malathy Krishnamurthy Juan R Cubillos-Ruiz Deborah A Hogan

Mol Microbiol 2010 Dec 18;78(6):1379-92. Epub 2010 Oct 18.

Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2010.07414.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828654PMC
December 2010

CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells.

Authors:
Juan R Cubillos-Ruiz Diana Martinez Uciane K Scarlett Melanie R Rutkowski Yolanda C Nesbeth Ana L Camposeco-Jacobs Jose R Conejo-Garcia

Oncotarget 2010 Sep;1(5):329-38

Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, NH 03756, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992324PMC
http://dx.doi.org/10.18632/oncotarget.165DOI Listing
September 2010

CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells.

Authors:
Yolanda C Nesbeth Diana G Martinez Seiko Toraya Uciane K Scarlett Juan R Cubillos-Ruiz Melanie R Rutkowski Jose R Conejo-Garcia

J Immunol 2010 May 16;184(10):5654-62. Epub 2010 Apr 16.

Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, NH 03756, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0903247
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http://dx.doi.org/10.4049/jimmunol.0903247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874073PMC
May 2010

Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes.

Authors:
Juan R Cubillos-Ruiz Melanie Rutkowski Jose R Conejo-Garcia

Cell Cycle 2010 Jan 26;9(2):260-8. Epub 2010 Jan 26.

Departments of Microbiology and Immunology, Lebanon, NH, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056209PMC
http://dx.doi.org/10.4161/cc.9.2.10430DOI Listing
January 2010

Nanomolecular targeting of dendritic cells for ovarian cancer therapy.

Authors:
Juan R Cubillos-Ruiz Steven Fiering Jose R Conejo-Garcia

Future Oncol 2009 Oct;5(8):1189-92

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http://dx.doi.org/10.2217/fon.09.101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056055PMC
October 2009

In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells.

Authors:
Uciane K Scarlett Juan R Cubillos-Ruiz Yolanda C Nesbeth Diana G Martinez Xavier Engle Andrew T Gewirtz Cory L Ahonen Jose R Conejo-Garcia

Cancer Res 2009 Sep 8;69(18):7329-37. Epub 2009 Sep 8.

Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, New Hampshire, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754806PMC
September 2009

Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity.

Authors:
Juan R Cubillos-Ruiz Xavier Engle Uciane K Scarlett Diana Martinez Amorette Barber Raul Elgueta Li Wang Yolanda Nesbeth Yvon Durant Andrew T Gewirtz Charles L Sentman Ross Kedl Jose R Conejo-Garcia

J Clin Invest 2009 Aug 13;119(8):2231-44. Epub 2009 Jul 13.

Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, New Hampshire, USA.

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http://dx.doi.org/10.1172/JCI37716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719935PMC
August 2009

Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity.

Authors:
Eduardo Huarte Juan R Cubillos-Ruiz Yolanda C Nesbeth Uciane K Scarlett Diana G Martinez Ronald J Buckanovich Fabian Benencia Radu V Stan Tibor Keler Pablo Sarobe Charles L Sentman Jose R Conejo-Garcia

Cancer Res 2008 Sep 3;68(18):7684-91. Epub 2008 Sep 3.

Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, New Hampshire 03766, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742361PMC
September 2008

PILAR is a novel modulator of human T-cell expansion.

Authors:
Eduardo Huarte Juan R Cubillos-Ruiz Yolanda C Nesbeth Uciane K Scarlett Diana G Martinez Xavier A Engle William F Rigby Patricia A Pioli Paul M Guyre Jose R Conejo-Garcia

Blood 2008 Aug 12;112(4):1259-68. Epub 2008 Jun 12.

Department ofMicrobiology and Immunology, Dartmouth Medical School, Lebanon, NH, USA.

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http://www.bloodjournal.org/content/112/4/1259.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2007-12-13
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http://dx.doi.org/10.1182/blood-2007-12-130773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515140PMC
August 2008