Publications by authors named "Juan Jose Lozano"

100Publications

Prognostic classifier for predicting biochemical recurrence in localized prostate cancer patients after radical prostatectomy.

Urol Oncol 2020 Nov 11. Epub 2020 Nov 11.

Laboratory and Department of Urology, Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2020.10.075DOI Listing
November 2020

Variability in Cerebrospinal Fluid MicroRNAs Through Life.

Mol Neurobiol 2020 Oct 16;57(10):4134-4142. Epub 2020 Jul 16.

Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Medicine and Nursing, University of The Basque Country (UPV/EHU), 48940, Leioa, Bizkaia, Spain.

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http://dx.doi.org/10.1007/s12035-020-02011-3DOI Listing
October 2020

Phosphoinositide 3-Kinase-Regulated Pericyte Maturation Governs Vascular Remodeling.

Circulation 2020 Aug 29;142(7):688-704. Epub 2020 May 29.

Vascular Biology and Signalling Group, ProCURE, Oncobell Program, Institut d´Investigació Biomèdica de Bellvitge (IDIBELL), Gran Via de l'Hospitalet 199, 08908 L´Hospitalet de Llobregat, Barcelona, Spain (A.M.F., P.V., P.K., A.M.-R., A.A.-U., M.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.042354DOI Listing
August 2020

MiR-93 is related to poor prognosis in pancreatic cancer and promotes tumor progression by targeting microtubule dynamics.

Oncogenesis 2020 May 4;9(5):43. Epub 2020 May 4.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd)/ Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41389-020-0227-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198506PMC
May 2020

Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.

J Med Genet 2020 Oct 13;57(10):677-682. Epub 2020 Mar 13.

Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic, Barcelona, Spain

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http://dx.doi.org/10.1136/jmedgenet-2019-106374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525772PMC
October 2020

CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications.

Elife 2020 Jan 15;9. Epub 2020 Jan 15.

Gastrointestinal and Pancreatic Oncology Team, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.7554/eLife.50267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010409PMC
January 2020

Validation of miR-1228-3p as Housekeeping for MicroRNA Analysis in Liquid Biopsies from Colorectal Cancer Patients.

Biomolecules 2019 12 20;10(1). Epub 2019 Dec 20.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) /Hospital Clínic of Barcelona/Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.3390/biom10010016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022916PMC
December 2019

Identification and Validation of MicroRNA Profiles in Fecal Samples for Detection of Colorectal Cancer.

Gastroenterology 2020 03 14;158(4):947-957.e4. Epub 2019 Oct 14.

Gastroenterology Department, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.10.005DOI Listing
March 2020

Analysis of A 6-Mirna Signature in Serum from Colorectal Cancer Screening Participants as Non-Invasive Biomarkers for Advanced Adenoma and Colorectal Cancer Detection.

Cancers (Basel) 2019 Oct 12;11(10). Epub 2019 Oct 12.

Gastrointestinal and Pancreatic Oncology Research Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD)/Hospital Clínic of Barcelona/Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Spain.

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http://dx.doi.org/10.3390/cancers11101542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827108PMC
October 2019

New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease.

Cells 2019 09 10;8(9). Epub 2019 Sep 10.

Liver Vascular Biology Research Group, Barcelona Hepatic Hemodynamic Laboratory, IDIBAPS Biomedical Research Institute, CIBEREHD, 08036 Barcelona, Spain.

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https://www.mdpi.com/2073-4409/8/9/1062
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http://dx.doi.org/10.3390/cells8091062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770035PMC
September 2019

Aging Influences Hepatic Microvascular Biology and Liver Fibrosis in Advanced Chronic Liver Disease.

Aging Dis 2019 Aug 1;10(4):684-698. Epub 2019 Aug 1.

1Liver Vascular Biology Research Group, Barcelona Hepatic Hemodynamic Laboratory, IDIBAPS Biomedical Research Institute, University of Barcelona Medical School, Barcelona, Spain.

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http://dx.doi.org/10.14336/AD.2019.0127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675529PMC
August 2019

Novel Circulating miRNA Signatures for Early Detection of Pancreatic Neoplasia.

Clin Transl Gastroenterol 2019 04;10(4):e00029

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD)/Hospital Clínic of Barcelona/Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Catalonia, Spain.

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http://Insights.ovid.com/crossref?an=01720094-201904000-0000
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http://dx.doi.org/10.14309/ctg.0000000000000029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602779PMC
April 2019

Quantitative analysis of somatically acquired and constitutive uniparental disomy in gastrointestinal cancers.

Int J Cancer 2019 02 3;144(3):513-524. Epub 2018 Dec 3.

Gastrointestinal and Pancreatic Oncology Group, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Catalonia, Spain.

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http://doi.wiley.com/10.1002/ijc.31936
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http://dx.doi.org/10.1002/ijc.31936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635747PMC
February 2019

Urine Gene Expression Profiles in Bladder Pain Syndrome Patients Treated with Triamcinolone.

Eur Urol Focus 2020 03 11;6(2):390-396. Epub 2018 Oct 11.

Department and Laboratory of Urology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.euf.2018.10.001DOI Listing
March 2020

Validation of Urine-based Gene Classifiers for Detecting Bladder Cancer in a Chinese Study.

J Cancer 2018 6;9(17):3208-3215. Epub 2018 Aug 6.

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.

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http://www.jcancer.org/v09p3208.htm
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http://dx.doi.org/10.7150/jca.24506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134826PMC
August 2018

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis.

Cell Stem Cell 2018 Jul 28;23(1):101-113.e7. Epub 2018 Jun 28.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.05.027DOI Listing
July 2018

Mutational Signatures in Cancer (MuSiCa): a web application to implement mutational signatures analysis in cancer samples.

BMC Bioinformatics 2018 06 14;19(1):224. Epub 2018 Jun 14.

Gastroenterology Department, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12859-018-2234-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001047PMC
June 2018

Molecular profiling of subclinical inflammatory lesions in long-term surviving adult liver transplant recipients.

J Hepatol 2018 09 28;69(3):626-634. Epub 2018 Apr 28.

Institute of Liver Studies, King's College Hospital, MRC Transplant Centre, King's College London University, London, England, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.04.012DOI Listing
September 2018

Prognostic value of circulating microRNAs in upper tract urinary carcinoma.

Oncotarget 2018 Mar 30;9(24):16691-16700. Epub 2018 Mar 30.

Department and Laboratory of Urology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.24672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908279PMC
March 2018

Deciphering microRNA targets in pancreatic cancer using miRComb R package.

Oncotarget 2018 Jan 8;9(5):6499-6517. Epub 2018 Jan 8.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.18632/oncotarget.24034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814228PMC
January 2018

Near-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness.

FASEB J 2018 07 8;32(7):3502-3517. Epub 2018 Feb 8.

Gastrointestinal and Pancreatic Oncology Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic de Barcelona, Barcelona, Spain.

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https://www.fasebj.org/doi/10.1096/fj.201700247RR
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http://dx.doi.org/10.1096/fj.201700247RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998968PMC
July 2018

The specialized proresolving lipid mediator maresin 1 protects hepatocytes from lipotoxic and hypoxia-induced endoplasmic reticulum stress.

FASEB J 2017 12 2;31(12):5384-5398. Epub 2017 Aug 2.

Department of Biochemistry and Molecular Genetics, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain;

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http://dx.doi.org/10.1096/fj.201700394RDOI Listing
December 2017

Up-regulation of EP and EP receptors in human tolerogenic dendritic cells boosts the immunosuppressive activity of PGE.

J Leukoc Biol 2017 09 19;102(3):881-895. Epub 2017 Jun 19.

Centro de Investigación Biomédica en Red, Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain;

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http://doi.wiley.com/10.1189/jlb.2A1216-526R
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http://dx.doi.org/10.1189/jlb.2A1216-526RDOI Listing
September 2017

Urinary cell microRNA-based prognostic classifier for non-muscle invasive bladder cancer.

Oncotarget 2017 Mar;8(11):18238-18247

Laboratory and Department of Urology, Hospital Clínic de Barcelona, Centre de Recerca Biomèdica CELLEX, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

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http://www.oncotarget.com/fulltext/15315
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http://dx.doi.org/10.18632/oncotarget.15315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392323PMC
March 2017

Pharmacogenomic analyzis of the responsiveness of gastrointestinal tumor cell lines to drug therapy: A transportome approach.

Pharmacol Res 2016 11 9;113(Pt A):364-375. Epub 2016 Sep 9.

Molecular Pharmacology and Experimental Therapeutics (MPET), Department of Biochemistry and Molecular Biology, Institute of Biomedicine (IBUB), University of Barcelona, Spain; Oncology Program, National Biomedical Research Institute on Liver and Gastrointestinal Diseases (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10436618163047
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http://dx.doi.org/10.1016/j.phrs.2016.09.007DOI Listing
November 2016

Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue.

J Immunol 2016 10 19;197(8):3360-3370. Epub 2016 Sep 19.

Department of Biochemistry and Molecular Genetics, Hospital Clínic, August Pi i Sunyer Biomedical Research Institute, Barcelona 08036, Spain;

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http://dx.doi.org/10.4049/jimmunol.1502522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101161PMC
October 2016

Simvastatin Attenuates Liver Injury in Rodents with Biliary Cirrhosis Submitted to Hemorrhage/Resuscitation.

Shock 2017 03;47(3):370-377

*Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), University of Barcelona, Barcelona, Spain †Division of Gastroenterology, Department of Medicine, University of Santa Catarina, Florianópolis, Brazil ‡CIBERehd (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas), Madrid, Spain §Swiss Liver Center, Inselspital, Bern University, Bern, Switzerland ||Division of Gastroenterology (Liver Unit), Department of Medicine, University of Alberta, CEGIIR, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1097/SHK.0000000000000734DOI Listing
March 2017

MicroRNAs for Detection of Pancreatic Neoplasia: Biomarker Discovery by Next-generation Sequencing and Validation in 2 Independent Cohorts.

Ann Surg 2017 06;265(6):1226-1234

*Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD)/Hospital Clínic of Barcelona/ Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Catalonia, Spain †Bioinformatics Platform, CIBEREHD/Barcelona, Catalonia, Spain ‡Pathology Department, Hospital Clínic of Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1097/SLA.0000000000001809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434964PMC
June 2017

Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.

Gut 2016 09 10;65(9):1535-45. Epub 2016 May 10.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.

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http://dx.doi.org/10.1136/gutjnl-2015-311314DOI Listing
September 2016

The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.

Eur J Hum Genet 2016 10 11;24(10):1501-5. Epub 2016 May 11.

Gastroenterology Department, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/ejhg.2016.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027689PMC
October 2016

Genetic Variants Associated with Colorectal Adenoma Susceptibility.

PLoS One 2016 14;11(4):e0153084. Epub 2016 Apr 14.

Department of Gastroenterology, Hospital del Mar, IMIM (Hospital del Mar Medical Research Institute), Pompeu Fabra University, Passeig Marítim 25-29, 08003, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153084PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831735PMC
August 2016

MiRComb: An R Package to Analyse miRNA-mRNA Interactions. Examples across Five Digestive Cancers.

PLoS One 2016 11;11(3):e0151127. Epub 2016 Mar 11.

Bioinformatics Platform, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151127PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788200PMC
December 2016

Using gene expression from urine sediment to diagnose prostate cancer: development of a new multiplex mRNA urine test and validation of current biomarkers.

BMC Cancer 2016 Feb 9;16:76. Epub 2016 Feb 9.

Laboratory and Department of Urology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12885-016-2127-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746764PMC
February 2016

Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma.

Gut 2017 03 11;66(3):530-540. Epub 2015 Dec 11.

Liver Cancer Translational Research Laboratory, Barcelona Clinic Liver Cancer (BCLC) Group, Liver Unit and Pathology Department, IDIBAPS, Hospital Clínic, CIBERehd, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1136/gutjnl-2015-309501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600200PMC
March 2017

Metabolomics as a diagnostic tool for idiopathic non-cirrhotic portal hypertension.

Liver Int 2016 07 27;36(7):1051-8. Epub 2015 Oct 27.

Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, Institut de Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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https://www.liverpool.ac.uk/pfg/PDF/05_Whitfield_Metab.pdf
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http://doi.wiley.com/10.1111/liv.12972
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http://dx.doi.org/10.1111/liv.12972DOI Listing
July 2016

Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response.

PLoS One 2015 19;10(8):e0136106. Epub 2015 Aug 19.

Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, Medical Research Council (MRC) Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London University, King's College Hospital, Denmark Hill, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136106PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542211PMC
May 2016

Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer.

Carcinogenesis 2015 Oct 4;36(10):1103-10. Epub 2015 Aug 4.

Unitat de Biologia Cellular i Genètica Mèdica, Departament de Biologia Cellular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Catalonia 08193, Spain, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Catalonia 08193, Spain,

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http://dx.doi.org/10.1093/carcin/bgv115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598814PMC
October 2015

Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells.

Sci Rep 2015 Jun 22;5:11549. Epub 2015 Jun 22.

1] Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain [2] Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain [3] Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.

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http://dx.doi.org/10.1038/srep11549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476106PMC
June 2015

MERTK as negative regulator of human T cell activation.

J Leukoc Biol 2015 Apr 26;97(4):751-60. Epub 2015 Jan 26.

*Fundació Clínic per a la Recerca Biomèdica, Barcelona, Spain; Instituto de Medicina Experimental, Academia Nacional de Medicina, Buenos Aires, Argentina; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain; 3ra Cátedra de Farmacologia, Facultad de Medicina, Universidad de Buenos Aires, Argentina; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona, Spain; Department of Gastroenterology, Hospital Clínic de Barcelona, Spain; and Department of Immunobiology, Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1189/jlb.3A0714-334RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370049PMC
April 2015

HCV-induced immune responses influence the development of operational tolerance after liver transplantation in humans.

Sci Transl Med 2014 Jun;6(242):242ra81

Liver Unit, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of Barcelona, Barcelona 08036, Spain. Institute of Liver Studies, MRC Centre for Transplantation, King's College London, London SE5 9RS, UK.

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http://dx.doi.org/10.1126/scitranslmed.3008793DOI Listing
June 2014

The biliary epithelium gives rise to liver progenitor cells.

Hepatology 2014 Oct 21;60(4):1367-77. Epub 2014 Aug 21.

Liver Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.

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http://dx.doi.org/10.1002/hep.27078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410184PMC
October 2014

Epithelial-to-mesenchymal transition mediates docetaxel resistance and high risk of relapse in prostate cancer.

Mol Cancer Ther 2014 May 21;13(5):1270-84. Epub 2014 Mar 21.

Authors' Affiliations: Laboratory of Translational Oncology and Medical Oncology Department; Bioinformatics Platform Department, Centro de Investigación Biomédica en Red-Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS); Laboratory and Department of Urology, Hospital Clínic, Barcelona; Department of Pathology, Hospital Clínic, Universitat de Barcelona; Althia; Tumor Bank, Hospital Clínic-IDIBAPS Biobank, Barcelona; Medical Oncology Department, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona; and Medical Oncology Department, Hospital Parc Taulí, Sabadell, Spain.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0775DOI Listing
May 2014

Identification of blood serum micro-RNAs associated with idiopathic and LRRK2 Parkinson's disease.

J Neurosci Res 2014 Aug 20;92(8):1071-7. Epub 2014 Mar 20.

Laboratory of Neurodegenerative Disorders, Department of Neurology, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)-Centro de Investigación sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/jnr.23377DOI Listing
August 2014

Multiple sporadic colorectal cancers display a unique methylation phenotype.

PLoS One 2014 18;9(3):e91033. Epub 2014 Mar 18.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091033PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958343PMC
December 2014

S-adenosylmethionine levels regulate the schwann cell DNA methylome.

Neuron 2014 Mar;81(5):1024-1039

CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Bizkaia Technology Park, Derio, 48160 Bizkaia, Spain; IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960855PMC
March 2014

New genes emerging for colorectal cancer predisposition.

World J Gastroenterol 2014 Feb;20(8):1961-71

Clara Esteban-Jurado, Anna Abulí, Jenifer Muñoz, Francesc Balaguer, Teresa Ocaña, Antoni Castells, Josep M Piqué, Sergi Castellví-Bel, Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.3748/wjg.v20.i8.1961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934466PMC
February 2014

Prognostic value of microRNA expression pattern in upper tract urothelial carcinoma.

BJU Int 2014 May;113(5):813-21

Department and Laboratory of Urology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/bju.12551DOI Listing
May 2014

Validation study of a noninvasive urine test for diagnosis and prognosis assessment of bladder cancer: evidence for improved models.

J Urol 2014 Jan 2;191(1):261-9. Epub 2013 Jul 2.

Laboratory and Department of Urology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.juro.2013.06.083DOI Listing
January 2014

Genetic susceptibility variants associated with colorectal cancer prognosis.

Carcinogenesis 2013 Oct 27;34(10):2286-91. Epub 2013 May 27.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Catalonia 08036, Spain.

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http://dx.doi.org/10.1093/carcin/bgt179DOI Listing
October 2013

Using microRNA profiling in urine samples to develop a non-invasive test for bladder cancer.

Int J Cancer 2013 Dec 14;133(11):2631-41. Epub 2013 Jun 14.

Laboratory and Department of Urology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.28274DOI Listing
December 2013

Curcumin modulates DNA methylation in colorectal cancer cells.

PLoS One 2013 27;8(2):e57709. Epub 2013 Feb 27.

Gastrointestinal Cancer Research Laboratory, Division of Gastroenterology, Baylor Research Institute, Baylor University Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057709PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584082PMC
September 2013

Metabolomics discloses potential biomarkers for the noninvasive diagnosis of idiopathic portal hypertension.

Am J Gastroenterol 2013 Jun 19;108(6):926-32. Epub 2013 Feb 19.

Liver Unit, Hepatic Hemodynamic Laboratory, Institut de Malalties Digestives i Metaboliques, Hospital Clínic-Institut de Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1038/ajg.2013.11DOI Listing
June 2013

Circulating microRNAs as biomarkers of colorectal cancer: results from a genome-wide profiling and validation study.

Clin Gastroenterol Hepatol 2013 Jun 23;11(6):681-8.e3. Epub 2012 Dec 23.

Department of Gastroenterology, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cgh.2012.12.009DOI Listing
June 2013

Gene-expression signature of tumor recurrence in patients with stage II and III colon cancer treated with 5'fluoruracil-based adjuvant chemotherapy.

Int J Cancer 2013 Mar 12;132(5):1090-7. Epub 2012 Aug 12.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, IDIBAPS*, University of Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/ijc.27747DOI Listing
March 2013

Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant.

J Am Soc Nephrol 2012 Apr 26;23(4):597-606. Epub 2012 Jan 26.

Institut National de la Santé Et de la Recherche Médicale UMR643 and Institut de Transplantation Urologie, Néphrologie, Nantes, France.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2011060543
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http://dx.doi.org/10.1681/ASN.2011060543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312506PMC
April 2012

Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis.

Hepatology 2012 Jun 23;55(6):1931-41. Epub 2012 Apr 23.

Liver Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona, Spain.

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http://dx.doi.org/10.1002/hep.25614DOI Listing
June 2012

Colorectal cancers with microsatellite instability display unique miRNA profiles.

Clin Cancer Res 2011 Oct 15;17(19):6239-49. Epub 2011 Aug 15.

Department of Internal Medicine, Division of Gastroenterology, Charles A. Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Center, Dallas, Texas 75246, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186834PMC
October 2011

Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.

Hepatology 2010 Dec 1;52(6):2096-108. Epub 2010 Oct 1.

Division of Gastroenterology and Liver Diseases, University of Southern California Research Center for Liver Diseases, Keck School of Medicine USC, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1002/hep.23919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005187PMC
December 2010

Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis.

Cancer Res 2010 Aug 3;70(16):6609-18. Epub 2010 Aug 3.

Department of Internal Medicine, Division of Gastroenterology, Charles A Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Center, Dallas, Texas 75246, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922409PMC
August 2010

Fecal MicroRNAs as novel biomarkers for colon cancer screening.

Cancer Epidemiol Biomarkers Prev 2010 Jul 15;19(7):1766-74. Epub 2010 Jun 15.

Gastrointestinal Cancer Research Laboratory, Baylor University Medical Center, Dallas, TX 75246, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901410PMC
July 2010

Protection from hepatic lipid accumulation and inflammation by genetic ablation of 5-lipoxygenase.

Prostaglandins Other Lipid Mediat 2010 Jun 21;92(1-4):54-61. Epub 2010 Mar 21.

Department of Biochemistry and Molecular Genetics, Hospital Clínic, IDIBAPS, CIBEK, University of Barcelona, Barcelona 08036, Spain.

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http://dx.doi.org/10.1016/j.prostaglandins.2010.03.001DOI Listing
June 2010

Identification of human specific gene duplications relative to other primates by array CGH and quantitative PCR.

Genomics 2010 Apr 11;95(4):203-9. Epub 2010 Feb 11.

Department of Animal Biology, Plant Biology and Ecology, Faculty of Biosciences, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ygeno.2010.02.003DOI Listing
April 2010

Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer.

PLoS One 2010 Jan 19;5(1):e8777. Epub 2010 Jan 19.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red en el Area temática de Enfermedades Hepáticas y Digestivas, Institut d'investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008777PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808250PMC
January 2010

Gene expression profiling and transplantation tolerance in the clinic.

Transplantation 2009 Aug;88(3 Suppl):S50-3

Liver Unit, Hospital Clinic Barcelona, IDIBAPS, CIBERehd, Villaroel 170, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1097/TP.0b013e3181af7d17DOI Listing
August 2009