Juan J Calvete

Juan J Calvete

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Juan J Calvete

Publications by authors named "Juan J Calvete"

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Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite.

Sci Transl Med 2020 May;12(542)

Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.

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http://dx.doi.org/10.1126/scitranslmed.aay8314DOI Listing
May 2020

Venomics and antivenomics of the poorly studied Brazil's lancehead, (Hoge, 1954), from the Brazilian State of Pará.

J Venom Anim Toxins Incl Trop Dis 2020 17;26:e20190103. Epub 2020 Apr 17.

Center for the Study of Biomolecules Applied to Health (CEBio), Oswaldo Cruz Foundation Rondônia, Porto Velho, RO, Brazil.

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http://dx.doi.org/10.1590/1678-9199-JVATITD-2019-0103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179968PMC
April 2020

The Harderian gland transcriptomes of Caraiba andreae, Cubophis cantherigerus and Tretanorhinus variabilis, three colubroid snakes from Cuba.

Genomics 2019 12 1;111(6):1720-1727. Epub 2018 Dec 1.

CIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, Porto 4450-208, Portugal; Department of Biology, University of Porto, Rua do Campo Alegre, s/n, Porto 4169-007, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2018.11.026DOI Listing
December 2019

Comparative venomics of Brazilian coral snakes: Micrurus frontalis, Micrurus spixii spixii, and Micrurus surinamensis.

Toxicon 2019 Aug 12;166:39-45. Epub 2019 May 12.

Centro de Estudos de Biomoléculas Aplicadas a Saúde (CEBio), Fundação Oswaldo Cruz de Rondônia (Fiocruz Rondônia), Porto Velho, RO, Brazil; Programa de Pós-graduação em Biologia Experimental (PGBIOEXP), Universidade Federal de Rondônia (UNIR), e Programa de Pós-graduação em Biodiversidade e Biotecnologia, Rede BIONORTE, Porto Velho, RO, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2019.05.001DOI Listing
August 2019

New insights into the phylogeographic distribution of the 3FTx/PLA venom dichotomy across genus Micrurus in South America.

J Proteomics 2019 05 1;200:90-101. Epub 2019 Apr 1.

Evolutionary and Translational Venomics Laboratory, CSIC, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2019.03.014DOI Listing
May 2019

Journal of Proteomics turns 10: Happy anniversary! and beyond.

Authors:
Juan J Calvete

J Proteomics 2019 04;198:iii

Evolutionary and Translational Venomics Laboratory, CSIC, Valencia, Spain.

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http://dx.doi.org/10.1016/j.jprot.2019.03.002DOI Listing
April 2019

Venom from Russia: Venomics, Bioactivities and Preclinical Assessment of Microgen Antivenom.

Toxins (Basel) 2019 02 1;11(2). Epub 2019 Feb 1.

Laboratorio de Venómica Evolutiva y Traslacional, CSIC, Jaime Roig 11, 46010 Valencia, Spain.

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http://dx.doi.org/10.3390/toxins11020090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409582PMC
February 2019

Enhanced Universal Quantification of Biomolecules Using Element MS and Generic Standards: Application to Intact Protein and Phosphoprotein Determination.

Anal Chem 2019 01 11;91(1):1105-1112. Epub 2018 Dec 11.

Department of Physical and Analytical Chemistry , University of Oviedo , Julián Clavería 8 , 33006 Oviedo , Spain.

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http://dx.doi.org/10.1021/acs.analchem.8b04731DOI Listing
January 2019

A novel pentameric phospholipase A myotoxin (PophPLA) from the venom of the pit viper Porthidium ophryomegas.

Int J Biol Macromol 2018 Oct 7;118(Pt A):1-8. Epub 2018 Jun 7.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2018.06.028DOI Listing
October 2018

Venom gland transcriptomics and microRNA profiling of juvenile and adult yellow-bellied sea snake, Hydrophis platurus, from Playa del Coco (Guanacaste, Costa Rica).

Toxicon 2018 Oct 4;153:96-105. Epub 2018 Sep 4.

Evolutionary and Translational Venomics Laboratory, Consejo Superior de Investigaciones Científicas (CSIC), Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2018.08.016DOI Listing
October 2018

Snake venomics - from low-resolution toxin-pattern recognition to toxin-resolved venom proteomes with absolute quantification.

Authors:
Juan J Calvete

Expert Rev Proteomics 2018 07 20;15(7):555-568. Epub 2018 Jul 20.

a Evolutionary and Translational Venomics Laboratory , CSIC , Valencia , Spain.

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http://dx.doi.org/10.1080/14789450.2018.1500904DOI Listing
July 2018

Toxin-resolved antivenomics-guided assessment of the immunorecognition landscape of antivenoms.

Toxicon 2018 Jun 25;148:107-122. Epub 2018 Apr 25.

Evolutionary and Translational Venomics Laboratory, Consejo Superior de Investigaciones Científicas (CSIC), Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2018.04.015DOI Listing
June 2018

Translational Venomics: Third-Generation Antivenomics of Anti-Siamese Russell's Viper, Daboia siamensis, Antivenom Manufactured in Taiwan CDC's Vaccine Center.

Trop Med Infect Dis 2018 Jun 15;3(2). Epub 2018 Jun 15.

Evolutionary and Translational Venomics Laboratory, Consejo Superior de Investigaciones Científicas (CSIC), 46010 Valencia, Spain.

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http://dx.doi.org/10.3390/tropicalmed3020066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073718PMC
June 2018

A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins.

Plant Biotechnol J 2018 03 22;16(3):727-736. Epub 2017 Sep 22.

Instituto de Biología Molecular y Celular de Plantas (IBMCP), Agencia Estatal Consejo Superior de Investigaciones Científicas, Universidad Politécnica de Valencia, Valencia, Spain.

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http://dx.doi.org/10.1111/pbi.12823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814581PMC
March 2018

Snakebite envenoming.

Nat Rev Dis Primers 2017 10 5;3:17079. Epub 2017 Oct 5.

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http://dx.doi.org/10.1038/nrdp.2017.79DOI Listing
October 2017

Integrated Venomics and Venom Gland Transcriptome Analysis of Juvenile and Adult Mexican Rattlesnakes Crotalus simus, C. tzabcan, and C. culminatus Revealed miRNA-modulated Ontogenetic Shifts.

J Proteome Res 2017 09 7;16(9):3370-3390. Epub 2017 Aug 7.

Instituto de Biomedicina de Valencia , Consejo Superior de Investigaciones Científicas, Jaime Roig 11, 46010 Valencia, Spain.

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http://dx.doi.org/10.1021/acs.jproteome.7b00414DOI Listing
September 2017

Snakebite envenoming.

Nat Rev Dis Primers 2017 Sep 14;3:17063. Epub 2017 Sep 14.

Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/nrdp.2017.63DOI Listing
September 2017

Erratum to "Absolute venomics: Absolute quantification of intact venom proteins through elemental mass spectrometry".

J Proteomics 2017 08;165:138-140

Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (CSIC), Jaume Roig 11, 46010 Valencia, Spain.

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http://dx.doi.org/10.1016/j.jprot.2017.07.009DOI Listing
August 2017

Absolute venomics: Absolute quantification of intact venom proteins through elemental mass spectrometry.

J Proteomics 2017 07 2;164:33-42. Epub 2017 Jun 2.

Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (CSIC), Jaume Roig 11, 46010 Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2017.06.001DOI Listing
July 2017

Drought Tolerance in Seed Sources As Identified by Distinctive Physiological and Molecular Markers.

Front Plant Sci 2017 24;8:1202. Epub 2017 Jul 24.

Instituto de Biología Molecular y Celular de Plantas, Universitat Politècnica de València - Consejo Superior de Investigaciones CientíficasValencia, Spain.

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http://dx.doi.org/10.3389/fpls.2017.01202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523154PMC
July 2017

Third Generation Antivenomics: Pushing the Limits of the In Vitro Preclinical Assessment of Antivenoms.

Toxins (Basel) 2017 05 10;9(5). Epub 2017 May 10.

Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, Jaime Roig 11, 46010 Valencia, Spain.

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http://dx.doi.org/10.3390/toxins9050158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450706PMC
May 2017

Venom On-a-Chip: A Fast and Efficient Method for Comparative Venomics.

Toxins (Basel) 2017 05 28;9(6). Epub 2017 May 28.

Molecular Ecology and Fisheries Genetics Lab, School of Biological Sciences, Bangor University, Bangor LL57 2UW, UK.

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http://dx.doi.org/10.3390/toxins9060179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488029PMC
May 2017

What killed Karl Patterson Schmidt? Combined venom gland transcriptomic, venomic and antivenomic analysis of the South African green tree snake (the boomslang), Dispholidus typus.

Biochim Biophys Acta Gen Subj 2017 Apr 24;1861(4):814-823. Epub 2017 Jan 24.

Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335903PMC
April 2017

Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms.

J Venom Anim Toxins Incl Trop Dis 2017 28;23:26. Epub 2017 Apr 28.

Structural and Functional Venomics Laboratory, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.

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http://dx.doi.org/10.1186/s40409-017-0117-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408369PMC
April 2017

Protein-species quantitative venomics: looking through a crystal ball.

J Venom Anim Toxins Incl Trop Dis 2017 28;23:27. Epub 2017 Apr 28.

Department of Physical and Analytical Chemistry, University of Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1186/s40409-017-0116-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408492PMC
April 2017

Selection for higher fertility reflects in the seminal fluid proteome of modern domestic chicken.

Comp Biochem Physiol Part D Genomics Proteomics 2017 03 3;21:27-40. Epub 2016 Nov 3.

Department of Clinical and Experimental Medicine, University of Linköping, Linköping, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cbd.2016.10.006DOI Listing
March 2017

Venomics: integrative venom proteomics and beyond.

Authors:
Juan J Calvete

Biochem J 2017 02 20;474(5):611-634. Epub 2017 Feb 20.

Structural and Functional Venomics Laboratory, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain

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http://dx.doi.org/10.1042/BCJ20160577DOI Listing
February 2017

Proteomics and antivenomics of Papuan black snake (Pseudechis papuanus) venom with analysis of its toxicological profile and the preclinical efficacy of Australian antivenoms.

J Proteomics 2017 01 17;150:201-215. Epub 2016 Sep 17.

Charles Campbell Toxinology Centre, School of Medicine & Health Sciences, University of Papua New Guinea, Boroko, NCD, Papua New Guinea; Australian Venom Research Unit, Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.09.007DOI Listing
January 2017

Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis).

J Proteomics 2017 01 21;152:1-12. Epub 2016 Oct 21.

Structural and Functional Venomics Laboratory, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.10.006DOI Listing
January 2017

The challenge of integrating proximate and ultimate causes to reconstruct the natural histories of venoms: the evolutionary link.

Authors:
Juan J Calvete

Expert Rev Proteomics 2016 12 8;13(12):1059-1061. Epub 2016 Oct 8.

a Structural and Functional Venomics Laboratory, Department of Genomics and Proteomics , Instituto de Biomedicina de Valencia (CSIC) , Valencia , Spain.

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http://dx.doi.org/10.1080/14789450.2017.1242416DOI Listing
December 2016

Distribution of RPTLN Genes Across Reptilia: Hypothesized Role for RPTLN in the Evolution of SVMPs.

Integr Comp Biol 2016 11 1;56(5):989-1003. Epub 2016 Jun 1.

Instituto de Biomedicina de Valencia, CSIC, Laboratorio de Venómica Estructural y Funcional, Jaime Roig 11, Valencia, 46010, Spain.

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http://dx.doi.org/10.1093/icb/icw031DOI Listing
November 2016

Identification of the major proteins present in the seminal plasma of European eel, and how hormonal treatment affects their evolution. Correlation with sperm quality.

Comp Biochem Physiol A Mol Integr Physiol 2016 11 22;201:37-45. Epub 2016 Jun 22.

Grupo de Acuicultura y Biodiversidad, Instituto de Ciencia y Tecnología Animal, Universitat Politècnica de València, Camino de Vera s/n. 46022, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2016.06.025DOI Listing
November 2016

Elemental Mass Spectrometry for Absolute Intact Protein Quantification without Protein-Specific Standards: Application to Snake Venomics.

Anal Chem 2016 10 21;88(19):9699-9706. Epub 2016 Sep 21.

Department of Physical and Analytical Chemistry, University of Oviedo , Julián Clavería 8, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1021/acs.analchem.6b02585DOI Listing
October 2016

Top-down venomics of the East African green mamba, Dendroaspis angusticeps, and the black mamba, Dendroaspis polylepis, highlight the complexity of their toxin arsenals.

J Proteomics 2016 09 16;146:148-64. Epub 2016 Jun 16.

Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.06.018DOI Listing
September 2016

Preclinical evaluation of three polyspecific antivenoms against the venom of Echis ocellatus: Neutralization of toxic activities and antivenomics.

Toxicon 2016 Sep 1;119:280-8. Epub 2016 Jul 1.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2016.06.022DOI Listing
September 2016

Insights into the Evolution of a Snake Venom Multi-Gene Family from the Genomic Organization of Echis ocellatus SVMP Genes.

Toxins (Basel) 2016 07 12;8(7). Epub 2016 Jul 12.

Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas, Jaume Roig 11, 46010 València, Spain.

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http://dx.doi.org/10.3390/toxins8070216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963849PMC
July 2016

Constructing comprehensive venom proteome reference maps for integrative venomics.

Expert Rev Proteomics 2015 ;12(5):557-73

b 2 Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.

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http://dx.doi.org/10.1586/14789450.2015.1073590DOI Listing
June 2016

Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii.

Biochimie 2016 Jun 10;125:83-90. Epub 2016 Mar 10.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.

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http://dx.doi.org/10.1016/j.biochi.2016.03.004DOI Listing
June 2016

Venomic Analysis of the Poorly Studied Desert Coral Snake, Micrurus tschudii tschudii, Supports the 3FTx/PLA₂ Dichotomy across Micrurus Venoms.

Toxins (Basel) 2016 06 7;8(6). Epub 2016 Jun 7.

Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, Jaime Roig 11, Valencia 46010, Spain.

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http://dx.doi.org/10.3390/toxins8060178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926144PMC
June 2016

Ecological proteomics: is the field ripe for integrating proteomics into evolutionary ecology research?

J Proteomics 2016 Mar;135:1-3

Instituto de Biomedicina de Valencia, CSIC, Valencia, (Spain). Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.01.020DOI Listing
March 2016

Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids.

Toxicon 2015 Dec 29;107(Pt B):217-33. Epub 2015 Aug 29.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2015.08.016DOI Listing
December 2015

A bright future for integrative venomics.

Toxicon 2015 Dec 2;107(Pt B):159-62. Epub 2015 Nov 2.

Instituto Clodomiro Picado, Universidad de Costa Rica, Costa Rica. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2015.10.024DOI Listing
December 2015

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina.

Toxins (Basel) 2015 Dec 25;8(1). Epub 2015 Dec 25.

Instituto de Biomedicina de Valencia, CSIC, Jaime Roig 11, 46010 Valencia, Spain.

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http://dx.doi.org/10.3390/toxins8010009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728531PMC
December 2015

Evaluation of the preclinical efficacy of four antivenoms, distributed in sub-Saharan Africa, to neutralize the venom of the carpet viper, Echis ocellatus, from Mali, Cameroon, and Nigeria.

Toxicon 2015 Nov 28;106:97-107. Epub 2015 Sep 28.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2015.09.027DOI Listing
November 2015

Computational proteomics: Integrating mass spectral data into a biological context.

J Proteomics 2015 Nov;129:1-2

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2015.10.013DOI Listing
November 2015

A Call for Incorporating Social Research in the Global Struggle against Snakebite.

PLoS Negl Trop Dis 2015 Sep 17;9(9):e0003960. Epub 2015 Sep 17.

Australian Venom Research Unit, Department of Pharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, Australia; Charles Campbell Toxinology Centre, School of Medicine & Health Sciences, University of Papua New Guinea, Port Moresby, Papua New Guinea.

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http://dx.doi.org/10.1371/journal.pntd.0003960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574917PMC
September 2015

The proteome quest to understand biology and disease (HUPO 2014).

J Proteomics 2015 Sep;127(Pt B):223-4

Proteomics Laboratory, Center for Applied Medical Research (CIMA), University of Navarra, CIBERHED, IDISNA, ProteoRed-PRB(2), 31008 Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2015.09.025DOI Listing
September 2015

Quaternary structure of Dioclea grandiflora lectin assessed by equilibrium sedimentation and crystallographic analysis of recombinant mutants.

FEBS Lett 2015 Aug 27;589(18):2290-6. Epub 2015 Jul 27.

Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.07.020DOI Listing
August 2015

Anti-angiogenic activities of snake venom CRISP isolated from Echis carinatus sochureki.

Biochim Biophys Acta 2015 Jun 7;1850(6):1169-79. Epub 2015 Feb 7.

Temple University, College of Engineering, Department of Bioengineering, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2015.02.002DOI Listing
June 2015

Venom Proteomics of Indonesian King Cobra, Ophiophagus hannah: Integrating Top-Down and Bottom-Up Approaches.

J Proteome Res 2015 Jun 27;14(6):2539-56. Epub 2015 Apr 27.

‡Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, 46010 Valencia, Spain.

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http://dx.doi.org/10.1021/acs.jproteome.5b00305DOI Listing
June 2015

NMR structure of bitistatin – a missing piece in the evolutionary pathway of snake venom disintegrins.

FEBS J 2015 Jan 17;282(2):341-60. Epub 2014 Nov 17.

Laboratory of Structural Biochemistry, Centro de Investigación Príncipe Felipe, Valencia, Spain.

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http://dx.doi.org/10.1111/febs.13138DOI Listing
January 2015

Omics meets biology: application to the design and preclinical assessment of antivenoms.

Toxins (Basel) 2014 Dec 15;6(12):3388-405. Epub 2014 Dec 15.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José 11501, Costa Rica.

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http://dx.doi.org/10.3390/toxins6123388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280540PMC
December 2014

Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: an antivenomics and neutralization study.

J Proteomics 2014 Oct 28;110:198-208. Epub 2014 Jun 28.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.06.016DOI Listing
October 2014

Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka.

J Proteomics 2014 Oct 8;110:209-29. Epub 2014 Aug 8.

Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (CSIC), Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.07.019DOI Listing
October 2014

Characterization and cDNA sequence of Bothriechis schlegeliil-amino acid oxidase with antibacterial activity.

Int J Biol Macromol 2014 Aug 26;69:200-7. Epub 2014 May 26.

Consejo Superior de Investigaciones Científicas, Jaume Roig 11, 46010 Valencia, Spain.

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http://dx.doi.org/10.1016/j.ijbiomac.2014.05.039DOI Listing
August 2014

Peptides with in vitro anti-tumor activity from the venom of the Eastern green mamba, Dendroaspis angusticeps (Elapidae).

J Venom Res 2014 19;5:16-21. Epub 2014 Jun 19.

Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102125PMC
July 2014

A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming.

Bull World Health Organ 2014 Jul 4;92(7):526-32. Epub 2014 Mar 4.

Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, Australia .

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http://dx.doi.org/10.2471/BLT.13.132431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121869PMC
July 2014

Immunological profile of antivenoms: preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays.

J Proteomics 2014 Jun 28;105:340-50. Epub 2014 Feb 28.

Instituto de Biomedicina de Valencia, CSIC, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.02.021DOI Listing
June 2014

Next-generation snake venomics: protein-locus resolution through venom proteome decomplexation.

Authors:
Juan J Calvete

Expert Rev Proteomics 2014 Jun 29;11(3):315-29. Epub 2014 Mar 29.

Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas, Jaime Roig 11, 46010 Valencia, Spain +34 963 391 778 +34 963 690 800

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http://dx.doi.org/10.1586/14789450.2014.900447DOI Listing
June 2014

Challenges and prospects of proteomics of non-model organisms.

Authors:
Juan J Calvete

J Proteomics 2014 Jun;105:1-4

Instituto de Biomedicina de Valencia CSIC, Jaime Roig 11, 46010 Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.04.034DOI Listing
June 2014

The expanding universe of mass analyzer configurations for biological analysis.

Authors:
Juan J Calvete

Methods Mol Biol 2014 ;1072:61-81

Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.

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http://dx.doi.org/10.1007/978-1-62703-631-3_6DOI Listing
May 2014

New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India.

Indian J Med Res 2013 ;138:38-59

Global Snakebite Initiative, P.O. Box 193, Herston, Qld, 4029, Australia; Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK, .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767246PMC
April 2014

Phylogeny-based comparative analysis of venom proteome variation in a clade of rattlesnakes (Sistrurus sp.).

PLoS One 2013 24;8(6):e67220. Epub 2013 Jun 24.

Department of Evolution, Ecology and Organismal Biology, Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067220PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691181PMC
February 2014

Venomics of New World pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon.

J Proteomics 2014 Jan 7;96:103-16. Epub 2013 Nov 7.

Laboratorio de Venómica y Proteinómica Estructural, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2013.10.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294458PMC
January 2014

Putting value in biomarker research and reporting.

J Proteomics 2014 Jan;96:A1-3

Laboratorio de Venómica y Proteinómica Estructural, Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.

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http://dx.doi.org/10.1016/j.jprot.2013.12.002DOI Listing
January 2014

Snake venomics: from the inventory of toxins to biology.

Authors:
Juan J Calvete

Toxicon 2013 Dec 9;75:44-62. Epub 2013 Apr 9.

Venomics and Structural Proteomics Laboratory, Instituto de Biomedicina de Valencia, CSIC, Jaume Roig 11, 46010 Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2013.03.020DOI Listing
December 2013

Amino acid sequence and biological characterization of BlatPLA₂, a non-toxic acidic phospholipase A₂ from the venom of the arboreal snake Bothriechis lateralis from Costa Rica.

Toxicon 2013 Oct 16;73:71-80. Epub 2013 Jul 16.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José 11501, Costa Rica.

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http://dx.doi.org/10.1016/j.toxicon.2013.07.008DOI Listing
October 2013

Cytotoxic activities of [Ser⁴⁹]phospholipase A₂ from the venom of the saw-scaled vipers Echis ocellatus, Echis pyramidum leakeyi, Echis carinatus sochureki, and Echis coloratus.

Toxicon 2013 Sep 4;71:96-104. Epub 2013 Jun 4.

Department of Biochemistry, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 17666, United Arab Emirates.

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http://dx.doi.org/10.1016/j.toxicon.2013.05.017DOI Listing
September 2013

Assessing the preclinical efficacy of antivenoms: from the lethality neutralization assay to antivenomics.

Toxicon 2013 Jul 29;69:168-79. Epub 2012 Nov 29.

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.

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http://dx.doi.org/10.1016/j.toxicon.2012.11.016DOI Listing
July 2013

Identification of inhibitors of α2β1 integrin, members of C-lectin type proteins, in Echis sochureki venom.

Toxicol Appl Pharmacol 2013 May 13;269(1):34-42. Epub 2013 Mar 13.

Department of Biology, Temple University, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.1016/j.taap.2013.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627822PMC
May 2013

The continuing saga of snake venom disintegrins.

Authors:
Juan J Calvete

Toxicon 2013 Feb 23;62:40-9. Epub 2012 Sep 23.

Instituto de Biomedicina de Valencia, CSIC, Jaime Roig 11, 46010 Valencia, Spain.

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http://dx.doi.org/10.1016/j.toxicon.2012.09.005DOI Listing
February 2013