Juan I Arostegui

Juan I Arostegui

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Juan I Arostegui

Juan I Arostegui

Publications by authors named "Juan I Arostegui"

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Acquired Cold Urticaria vs. Autoinflammatory Diseases, Genetic and Clinical Profile and Differential Diagnosis: Study of a Cohort of Patients in a Tertiary Reference Centre.

Acta Derm Venereol 2019 08 13. Epub 2019 Aug 13.

Department of Dermatology, Hospital del Mar- Institut Mar d'Investigacions Mèdiques, Universitat Autònoma de Barcelona (UAB), ES-08003 Barcelona, Spain.

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http://dx.doi.org/10.2340/00015555-3292DOI Listing
August 2019

MCC950 closes the active conformation of NLRP3 to an inactive state.

Nat Chem Biol 2019 06 13;15(6):560-564. Epub 2019 May 13.

Biomedical Research Institute of Murcia (IMIB-Arrixaca), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.

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http://www.nature.com/articles/s41589-019-0278-6
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http://dx.doi.org/10.1038/s41589-019-0278-6DOI Listing
June 2019

Chronic urticaria in infants as the first manifestation of autoinflammatory disease.

Pediatr Dermatol 2018 Nov 30;35(6):e337-e340. Epub 2018 Aug 30.

Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

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http://dx.doi.org/10.1111/pde.13619DOI Listing
November 2018

Evolving M-protein pattern in patients with smoldering multiple myeloma: impact on early progression.

Leukemia 2018 06 2;32(6):1427-1434. Epub 2018 Feb 2.

Department of Hematology, Amyloidosis and Myeloma Unit, Hospital Clínic, IDIBAPS, University of Barcelona, Villarroel 170, 08036, Barcelona, Spain.

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http://www.nature.com/articles/s41375-018-0013-4
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http://dx.doi.org/10.1038/s41375-018-0013-4DOI Listing
June 2018

Prognostic impact of immunoparesis at diagnosis and after treatment onset in patients with light-chain amyloidosis.

Amyloid 2017 Dec 20;24(4):245-252. Epub 2017 Oct 20.

a Department of Hematology , Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/13506129.2017.1390451DOI Listing
December 2017

Cryopyrin-associated Periodic Syndromes in Italian Patients: Evaluation of the Rate of Somatic NLRP3 Mosaicism and Phenotypic Characterization.

J Rheumatol 2017 Nov 15;44(11):1667-1673. Epub 2017 Sep 15.

From these departments of the Istituto Giannina Gaslini, Genoa: Unità Operativa Complessa (UOC) Genetica Medica, UO Pediatria II, Laboratorio Fisiopatologia dell'Uremia, Core facilities, and Neuroradiology Unit; Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Burlo Garofolo, Trieste; Department of Pediatrics, Immunology and Rheumatology Section, University of Pisa, Pisa; Division of Rheumatology, Department of Pediatric Medicine, Bambino Gesù Children's Hospital, IRCCS, Rome; Pediatric Clinic, Azienda Socio Sanitaria Territoriale (ASST) Spedali Civili and University of Brescia, Brescia; Amyloidosis Research and Treatment Centre, Biotechnology Research Laboratories, Fondazione IRCCS Policlinico San Matteo, Pavia; Department of Pediatrics, Azienda G. Martino, University of Messina, Messina; Department of Pediatrics, Immunology and Rheumatology, University of Torino, Torino; Cell Biology Unit, IRCCS L'Azienda Ospedaliera Universitaria (AOU) San Martino, San Martino, Italy; Department of Immunology, Hospital Clínic-Institut d'Investigacions Biomdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.3899/jrheum.170041DOI Listing
November 2017

Impact of Autologous Stem Cell Transplantation on the Incidence and Outcome of Oligoclonal Bands in Patients with Light-Chain Amyloidosis.

Biol Blood Marrow Transplant 2017 Aug 18;23(8):1269-1275. Epub 2017 Apr 18.

Amyloidosis and Myeloma Unit, Department of Hematology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791173040
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http://dx.doi.org/10.1016/j.bbmt.2017.04.012DOI Listing
August 2017

Efficacy of anakinra in an adult patient with recurrent pericarditis and cardiac tamponade as initial manifestations of tumor necrosis factor receptor-associated periodic syndrome due to the R92Q TNFRSF1A variant.

Int J Rheum Dis 2017 Apr 19;20(4):510-514. Epub 2016 Dec 19.

Department of Internal Medicine, Bellvitge University Hospital-IDIBELL, L'Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1111/1756-185X.13029DOI Listing
April 2017

DNA demethylation of inflammasome-associated genes is enhanced in patients with cryopyrin-associated periodic syndromes.

J Allergy Clin Immunol 2017 01 7;139(1):202-211.e6. Epub 2016 Jul 7.

Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.05.016DOI Listing
January 2017

The inflammasome pathway in stable COPD and acute exacerbations.

ERJ Open Res 2016 Jul 11;2(3). Epub 2016 Jul 11.

Fundació Clinic per a la Recerca Biomèdica, Barcelona, Spain; CIBER Respiratory Diseases (CIBERES), Barcelona, Spain; Institut Respiratori, Hospital Clinic, Barcelona, Spain; Biomedic Research Institute August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1183/23120541.00002-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034597PMC
July 2016

Clues to management of neonatally diagnosed BTK deficiency.

Pediatr Allergy Immunol 2016 06 16;27(4):428-30. Epub 2016 Mar 16.

Department of Pediatric Allergy and Clinical Immunology, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/pai.12549DOI Listing
June 2016

[Schnitzler syndrome: Report of 3 cases].

Med Clin (Barc) 2016 Jun 5;146(11):e63-5. Epub 2016 Mar 5.

Unidad de Amiloidosis y Mieloma, Servicio de Hematología, Hospital Clínic de Barcelona, Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS), Barcelona, España. Electronic address:

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http://dx.doi.org/10.1016/j.medcli.2015.12.016DOI Listing
June 2016

Prognostic Impact of Serum Heavy/Light Chain Pairs in Patients With Monoclonal Gammopathy of Undetermined Significance and Smoldering Myeloma: Long-Term Results From a Single Institution.

Clin Lymphoma Myeloma Leuk 2016 Jun 27;16(6):e71-7. Epub 2016 Feb 27.

Department of Hematology, Amyloidosis and Myeloma Unit, Hospital Clínic, Barcelona, and Institut d'Investigacions Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.clml.2016.02.034DOI Listing
June 2016

Brief Report: First Identification of Intrafamilial Recurrence of Blau Syndrome due to Gonosomal NOD2 Mosaicism.

Arthritis Rheumatol 2016 Apr;68(4):1039-44

Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.

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http://dx.doi.org/10.1002/art.39519DOI Listing
April 2016

Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants.

Sci Rep 2016 Mar 10;6:22889. Epub 2016 Mar 10.

Academic Unit of Ophthalmology, School of Clinical Sciences and School of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TH, UK.

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http://dx.doi.org/10.1038/srep22889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785391PMC
March 2016

Efficacy and safety of canakinumab in cryopyrin-associated periodic syndromes: results from a Spanish cohort.

Clin Exp Rheumatol 2015 Nov-Dec;33(6 Suppl 94):S67-71. Epub 2015 Aug 5.

Department of Immunology-CDB, Hospital Clínic-IDIBAPS, Barcelona, Spain.

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January 2016

Clinical and genetic characterization of the autoinflammatory diseases diagnosed in an adult reference center.

Autoimmun Rev 2016 Jan 21;15(1):9-15. Epub 2015 Aug 21.

Autoinflammatory Diseases Clinical Unit, Department of Autoimmune Diseases, Working Group of Adult Rare Diseases, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.autrev.2015.08.008DOI Listing
January 2016

Somatic NOD2 mosaicism in Blau syndrome.

J Allergy Clin Immunol 2015 Aug 25;136(2):484-7.e2. Epub 2015 Feb 25.

Department of Immunology-CDB, Hospital Clínic-IDIBAPS, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.12.1941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530052PMC
August 2015

Non-Hodgkin lymphoma in pediatric patients with common variable immunodeficiency.

Eur J Pediatr 2015 Aug 10;174(8):1069-76. Epub 2015 Mar 10.

Pediatric Allergy and Clinical Immunology Department, Hospital Sant Joan de Déu-Universitat de Barcelona, Passeig Sant Joan de Déu, 2, 08950, Esplugues de Llobregat, Barcelona, Spain,

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http://dx.doi.org/10.1007/s00431-015-2508-6DOI Listing
August 2015

Blau syndrome: cross-sectional data from a multicentre study of clinical, radiological and functional outcomes.

Rheumatology (Oxford) 2015 Jun 20;54(6):1008-16. Epub 2014 Nov 20.

Pediatrics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA, Department of Radiology, Department of Ophthalmology, Catholic University of Leuven (KU Leuven), Leuven, Belgium, Unidad de Reumatologia Pediatrica, Universidad de Barcelona, Barcelona, Spain, Unité d'Immunologie, Hématologie et Rhumatologie Pediatrique, Hospital Necker-Enfants Malades, Inserm U 768, Imagine Foundation, Paris, Rheumatology Practice, Neuilly-sur-Seine, France, Dipartimento di Pediatria, Universita degli Studi di Firenze, Firenze, Italy, Seccion Reumatologia, Universidad de Buenos Aires, Buenos Aires, Argentina, Fundación Biomédica Galicia Sur Hospital Meixoeiro, Hospital do Meixoeiro, Vigo, Spain, Service de Médecine Interne, Hôpital Claude Huriez, Lille, France, Department of Rheumatology, University of Zagreb, Zagreb, Croatia, Department of Paediatrics, Jaslok Hospital, Mumbai, India, Interdisciplinary Uveitis Center, Universitat Klinikum Heidelberg, Heidelberg, Germany, Unidad de Reumatologia Pediatrica, Hospital La Paz, Madrid, Servicio de Rheumatologia, Hospital de Gran Canarias Dr Negrin, Las Palmas, Spain, Instituto de Puericultura e Pediatria Martagao Gesteira (IPPMG), Universidad Federal do Rio de Janeiro, Rio de Janeiro, Brazil, Pédiatrie - Néphrologie, Médecine Interne et Hypertension, Hôpital des Enfants, Toulouse, France, Servicio de Immunologia/Reumatologia, University of Buenos Aires, Buenos Aires, Argentina, Pediatric Clinic, Centre Hospitalier de Luxemburg, Luxembourg, Luxembourg, Division of Pediatrics, Department of Pediatric Immunology and Rheumatology, UMC Utrecht, Utrecht, The Netherlands, Department of Immunology-CDB, Hospital Clinic Barcelona, Spain, Pattern Recognition Receptor Discovery Performance Unit, Immuno-inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA and Department of Pediatric Rheumatology, Catholic University of Leuven (KU Leuven), Leuven, Belgium

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http://dx.doi.org/10.1093/rheumatology/keu437DOI Listing
June 2015

Optic nerve and retinal features in uveitis associated with juvenile systemic granulomatous disease (Blau syndrome).

Acta Ophthalmol 2015 May 10;93(3):253-7. Epub 2014 Sep 10.

Bristol Eye Hospital, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

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http://dx.doi.org/10.1111/aos.12544DOI Listing
May 2015

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

Nat Immunol 2014 Aug 22;15(8):738-48. Epub 2014 Jun 22.

1] Inflammation and Experimental Surgery Unit, CIBERehd, Institute for Bio-Health Research of Murcia, Clinical University Hospital Virgen de la Arrixaca, Murcia, Spain. [2] Faculty of Life Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/ni.2919DOI Listing
August 2014

CIAS1 and NOD2 genes in adult-onset Still's disease.

J Rheumatol 2014 Jul;41(7):1566-7

Department of Rheumatology, Hospital Germans Trias i Pujol, Barcelona, Spain.

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http://dx.doi.org/10.3899/jrheum.131563DOI Listing
July 2014

Hyper-IgD and periodic fever syndrome: a new MVK mutation (p.R277G) associated with a severe phenotype.

Gene 2014 Jun 18;542(2):217-20. Epub 2014 Mar 18.

Pediatric Rheumatology, Hospital Dona Estefânia, CHLC, EPE, Lisbon, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2014.03.031DOI Listing
June 2014

Vasculitis syndromes: New insights into the molecular basis of systemic vasculitis.

Nat Rev Rheumatol 2014 Jun 13;10(6):323-4. Epub 2014 May 13.

Department of Immunology, Biomedical Diagnostic Centre, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomediques August Pi Sunyer (IDIBAPS), Villarroel 170, Barcelona 08036, Spain.

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http://dx.doi.org/10.1038/nrrheum.2014.75DOI Listing
June 2014

Differential humoral responses against heat-shock proteins after autologous stem cell transplantation in multiple myeloma.

Ann Hematol 2014 Jan 12;93(1):107-11. Epub 2013 Nov 12.

Department of Hematology, Amyloidosis and Myeloma Unit, Hospital Clínic, Barcelona, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00277-013-1942-7DOI Listing
January 2014

Massively parallel sequencing reveals maternal somatic IL2RG mosaicism in an X-linked severe combined immunodeficiency family.

J Allergy Clin Immunol 2013 Sep 15;132(3):741-743.e2. Epub 2013 May 15.

Immunology Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.03.038DOI Listing
September 2013

A novel phenotype variant of severe congenital neutropenia caused by G6PC3 deficiency.

Pediatr Blood Cancer 2013 Jul 25;60(7):E29-31. Epub 2013 Feb 25.

Clinical Immunology Service, University Hospital Reina Sofía, Córdoba, Spain.

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http://dx.doi.org/10.1002/pbc.24499DOI Listing
July 2013

Natural history and prognostic impact of oligoclonal humoral response in patients with multiple myeloma after autologous stem cell transplantation: long-term results from a single institution.

Haematologica 2013 Jul 3;98(7):1142-6. Epub 2013 May 3.

Department of Hematology, Amyloidosis and Myeloma Unit, Hospital Clínic, Barcelona, Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3324/haematol.2013.084350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696619PMC
July 2013

Prognostic impact of serum immunoglobulin heavy/light chain ratio in patients with multiple myeloma in complete remission after autologous stem cell transplantation.

Biol Blood Marrow Transplant 2012 Jul 16;18(7):1076-9. Epub 2012 Mar 16.

Department of Hematology, Amyloidosis and Myeloma Unit, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbmt.2012.03.004DOI Listing
July 2012

[Hereditary systemic autoinflammatory diseases].

Reumatol Clin 2011 Jan-Feb;7(1):45-50. Epub 2010 May 13.

Unidad de Enfermedades Autoinflamatorias, Servicio de Inmunología, Hospital Clínic, Villarroel, Barcelona, España.

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http://dx.doi.org/10.1016/j.reuma.2010.01.010DOI Listing
February 2012

[Pathophysiological mechanisms underlying cryopyrin-associated periodic syndromes: genetic and molecular basis and the inflammasome].

Med Clin (Barc) 2011 Jan;136 Suppl 1:22-8

Unidad de Enfermedades Autoinflamatorias, Servicio de Inmunología, Hospital Clínic de Barcelona, Barcelona, España.

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http://dx.doi.org/10.1016/S0025-7753(11)70005-7DOI Listing
January 2011

Cerebrospinal fluid neopterin and cryopyrin-associated periodic syndrome.

Pediatr Neurol 2009 Dec;41(6):448-50

Department of Neurology, Hospital Sant Joan de Déu, University of Barcelona, 08950 Esplugues de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.pediatrneurol.2009.06.008DOI Listing
December 2009

[Hereditary systemic autoinflammatory diseases. Part II: cryopyrin-associated periodic syndromes, pediatric systemic granulomatosis and PAPA syndrome].

Med Clin (Barc) 2008 Mar;130(11):429-38

Unidad de Enfermedades Autoinflamatorias Sistémicas, Servicio de Inmunología, Centro de Diagnóstico Biomédico (CDB), Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.1157/13117854DOI Listing
March 2008

A fatal Turkish case of CINCA-NOMID syndrome due to the novel Val-351-Leu CIAS1 gene mutation.

Rheumatol Int 2008 Feb 8;28(4):379-83. Epub 2007 Aug 8.

Department of Pediatric Rheumatology, Erciyes University Faculty of Medicine, Talas, Kayseri, Turkey.

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http://dx.doi.org/10.1007/s00296-007-0432-4DOI Listing
February 2008

An unexpectedly high frequency of MEFV mutations in patients with anti-citrullinated protein antibody-negative palindromic rheumatism.

Arthritis Rheum 2007 Aug;56(8):2784-8

Institut d'Investigacions Biomèdiques August Pi i Sunyer, and Servei de Reumatologia, Hospital Clínic de Barcelona, Villaroel 170, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1002/art.22755DOI Listing
August 2007

[Hereditary systemic autoinflammatory diseases. Hereditary periodic fever syndromes].

Med Clin (Barc) 2007 Jul;129(7):267-77

Unidad de Enfermedades Autoinflamatorias Sistémicas, Servicio de Inmunología, Centro de Diagnóstico Biomédico (CDB), Hospital Clínic, Barcelona, España.

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http://dx.doi.org/10.1157/13108350DOI Listing
July 2007

[Tumor necrosis factor receptor associated periodic syndrome (TRAPS). Report of two cases].

Rev Med Chil 2006 Dec 24;134(12):1558-61. Epub 2007 Jan 24.

Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago de Chile.

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http://dx.doi.org//S0034-98872006001200010DOI Listing
December 2006

Association of intermittent hydrarthrosis with MEFV gene mutations.

Arthritis Rheum 2006 Jul;54(7):2334-5

Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.1002/art.21923DOI Listing
July 2006

The west side story: MEFV haplotype in Spanish FMF patients and controls, and evidence of high LD and a recombination "hot-spot" at the MEFV locus.

Hum Mutat 2004 Apr;23(4):399

Servei d'Immunologia, Institut d'Investigacions Biomèdiques Agustí Pi i Sunyer, Hospital Clínic, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/humu.9229DOI Listing
April 2004