Juan Garcia-Vallejo

Juan Garcia-Vallejo

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Juan Garcia-Vallejo

Juan Garcia-Vallejo

Publications by authors named "Juan Garcia-Vallejo"

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74Publications

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OMIP-054: Broad Immune Phenotyping of Innate and Adaptive Leukocytes in the Brain, Spleen, and Bone Marrow of an Orthotopic Murine Glioblastoma Model by Mass Cytometry.

Cytometry A 2019 Apr 31;95(4):422-426. Epub 2019 Jan 31.

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology & Immunology, Amsterdam Infection & Immunity Institute and Cancer Center Amsterdam, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/cyto.a.23725
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http://dx.doi.org/10.1002/cyto.a.23725DOI Listing
April 2019

Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I.

Front Immunol 2018 14;9:1231. Epub 2018 Jun 14.

Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.01231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010527PMC
June 2018

Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity.

Front Immunol 2018 7;9:990. Epub 2018 May 7.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.00990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949514PMC
May 2018

Neuroinflammation: Microglia and T Cells Get Ready to Tango.

Front Immunol 2017 25;8:1905. Epub 2018 Jan 25.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2017.01905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788906PMC
January 2018

Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin inducing T cell anergy.

Sci Rep 2017 Apr 24;7:46748. Epub 2017 Apr 24.

Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.

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http://dx.doi.org/10.1038/srep46748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402274PMC
April 2017

Immune Regulates CD11c Cells by Interacting with the Macrophage Gal/GalNAc Lectin.

Front Immunol 2017 15;8:264. Epub 2017 Mar 15.

Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República , Montevideo , Uruguay.

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http://dx.doi.org/10.3389/fimmu.2017.00264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350155PMC
March 2017

A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K.

Cell Mol Life Sci 2016 12 16;73(24):4685-4699. Epub 2016 Jun 16.

Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country (UPV/EHU), Leioa, Spain.

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http://dx.doi.org/10.1007/s00018-016-2292-0DOI Listing
December 2016

New roles for CD14 and IL-β linking inflammatory dendritic cells to IL-17 production in memory CD4 T cells.

Immunol Cell Biol 2016 11 23;94(10):907-916. Epub 2016 Aug 23.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1038/icb.2016.66
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http://dx.doi.org/10.1038/icb.2016.66DOI Listing
November 2016

Human cytomegalovirus-based immunotherapy to treat glioblastoma: Into the future.

Oncoimmunology 2016 25;5(9):e1214791. Epub 2016 Jul 25.

Department of Molecular Cell Biology and Immunology, VUmc , Amsterdam, the Netherlands.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2016.1
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http://dx.doi.org/10.1080/2162402X.2016.1214791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048761PMC
July 2016

Apoptotic vesicles as tumor vaccine.

Immunotherapy 2016 7;8(1):5-8. Epub 2015 Dec 7.

Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2217/imt.15.96DOI Listing
June 2016

N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.

Mol Cell Proteomics 2016 Jan 4;15(1):124-40. Epub 2015 Nov 4.

From the ‡Center for Proteomics and Metabolomics, ‖Department of Molecular Cell Biology and Immunology and **Division of BioAnalytical Chemistry, VU University Medical Center, Amsterdam, The Netherlands;

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http://dx.doi.org/10.1074/mcp.M115.051235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762531PMC
January 2016

A new cellular target for Yersinia pestis.

Immunol Cell Biol 2015 Oct 30;93(9):769-70. Epub 2015 Jun 30.

Department of Molecular Cell Biology & Immunology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/icb.2015.60DOI Listing
October 2015

MPLA incorporation into DC-targeting glycoliposomes favours anti-tumour T cell responses.

J Control Release 2015 Oct 4;216:37-46. Epub 2015 Jul 4.

Department of Molecular Cell Biology and Immunology, VU University Medical Center (VUmc), Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.06.033DOI Listing
October 2015

mTOR Inhibition Per Se Induces Nuclear Localization of FOXP3 and Conversion of Invariant NKT (iNKT) Cells into Immunosuppressive Regulatory iNKT Cells.

J Immunol 2015 Sep 3;195(5):2038-45. Epub 2015 Aug 3.

Department of Medical Oncology, VU University Medical Center, 1081 HV Amsterdam, the Netherlands; and

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http://dx.doi.org/10.4049/jimmunol.1402710DOI Listing
September 2015

DC-SIGN: The Strange Case of Dr. Jekyll and Mr. Hyde.

Immunity 2015 Jun;42(6):983-5

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam MF-B242, 1081BT, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.05.021DOI Listing
June 2015

The Consequences of Multiple Simultaneous C-Type Lectin-Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN.

Front Immunol 2015 10;6:87. Epub 2015 Mar 10.

Department of Molecular Cell Biology and Immunology, VU University Medical Center , Amsterdam , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2015.00087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354414PMC
March 2015

Effective targeting of DC-SIGN by α-fucosylamide functionalized gold nanoparticles.

Bioconjug Chem 2014 Dec 24;25(12):2244-51. Epub 2014 Nov 24.

CNR-Institute of Molecular Science and Technologies (ISTM) , via Golgi 19, I-20133 Milan, Italy.

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http://dx.doi.org/10.1021/bc500467uDOI Listing
December 2014

DCIR interacts with ligands from both endogenous and pathogenic origin.

Immunol Lett 2014 Mar-Apr;158(1-2):33-41. Epub 2013 Nov 14.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2013.11.007DOI Listing
November 2014

Understanding the biology of antigen cross-presentation for the design of vaccines against cancer.

Front Immunol 2014 8;5:149. Epub 2014 Apr 8.

Department of Molecular Cell Biology and Immunology, VU University Medical Center , Amsterdam , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2014.00149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986565PMC
June 2014

Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors.

Cell 2014 Feb;156(4):744-58

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), 1428 Buenos Aires, Argentina; Laboratorio de Glicómica. Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.01.043DOI Listing
February 2014

Analytical tools for the study of cellular glycosylation in the immune system.

Front Immunol 2013 Dec 11;4:451. Epub 2013 Dec 11.

Department of Molecular Cell Biology and Immunology, VU University Medical Center , Amsterdam , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2013.00451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858669PMC
December 2013

The physiological role of DC-SIGN: a tale of mice and men.

Trends Immunol 2013 Oct 20;34(10):482-6. Epub 2013 Apr 20.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, 1081BT, The Netherlands.

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http://dx.doi.org/10.1016/j.it.2013.03.001DOI Listing
October 2013

Glycan-based DC-SIGN targeting vaccines to enhance antigen cross-presentation.

Mol Immunol 2013 Sep 14;55(2):143-5. Epub 2012 Nov 14.

Department of Molecular Cell Biology & Immunology, Faculty of Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2012.10.031DOI Listing
September 2013

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion.

J Leukoc Biol 2013 Aug 6;94(2):315-23. Epub 2013 Jun 6.

VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, the Netherlands.

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http://doi.wiley.com/10.1189/jlb.1012520
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http://dx.doi.org/10.1189/jlb.1012520DOI Listing
August 2013

Enhanced glycan nanoprofiling by weak anion exchange preparative chromatography, mild acid desialylation, and nanoliquid chromatography-mass spectrometry with nanofluorescence detection.

Electrophoresis 2013 Aug 26;34(16):2350-6. Epub 2013 Jul 26.

Department of Molecular Cell Biology & Immunology, Faculty of Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/elps.201200657DOI Listing
August 2013

Skin-resident antigen-presenting cells: instruction manual for vaccine development.

Front Immunol 2013 20;4:157. Epub 2013 Jun 20.

Department of Molecular Cell Biology and Immunology, VU University Medical Center , Amsterdam , Netherlands.

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http://journal.frontiersin.org/article/10.3389/fimmu.2013.00
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http://dx.doi.org/10.3389/fimmu.2013.00157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687254PMC
June 2013

Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells.

Front Immunol 2013 6;4:103. Epub 2013 May 6.

Department of Molecular Cell Biology and Immunology, VU University Medical Center Amsterdam, Netherlands ; Centre for Specialized Nutrition, Danone Research Wageningen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2013.00103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644800PMC
May 2013

Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells.

Mol Immunol 2013 Apr 24;53(4):387-97. Epub 2012 Oct 24.

Department of Molecular Cell Biology & Immunology, Faculty of Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2012.09.012DOI Listing
April 2013

Glycodendrimers prevent HIV transmission via DC-SIGN on dendritic cells.

Int Immunol 2013 Apr 4;25(4):221-33. Epub 2013 Jan 4.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/intimm/dxs115DOI Listing
April 2013

Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines.

Oncoimmunology 2013 Feb;2(2):e23040

Department of Molecular Cell Biology and Immunology; VU University Medical Center; Amsterdam, The Netherlands.

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http://dx.doi.org/10.4161/onci.23040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601176PMC
February 2013

BODIPY-labeled DC-SIGN-targeting glycodendrons efficiently internalize and route to lysosomes in human dendritic cells.

Biomacromolecules 2012 Oct 7;13(10):3209-19. Epub 2012 Sep 7.

Glycosystems Laboratory, Instituto de Investigaciones Químicas, Universidad de Sevilla, Seville, Spain.

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http://dx.doi.org/10.1021/bm300998cDOI Listing
October 2012

Online nanoliquid chromatography-mass spectrometry and nanofluorescence detection for high-resolution quantitative N-glycan analysis.

Anal Biochem 2012 Apr 28;423(1):153-62. Epub 2012 Jan 28.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, 1007 MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ab.2012.01.015DOI Listing
April 2012

Sortase A as a tool for high-yield histatin cyclization.

FASEB J 2011 Aug 27;25(8):2650-8. Epub 2011 Apr 27.

Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU Amsterdam, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1096/fj.11-182212DOI Listing
August 2011

Campylobacter jejuni lipooligosaccharides modulate dendritic cell-mediated T cell polarization in a sialic acid linkage-dependent manner.

Infect Immun 2011 Jul 18;79(7):2681-9. Epub 2011 Apr 18.

Department of Molecular Cell Biology and Immunology, Vrije Universiteit Medical Center, PO Box 7057, 1007MB Amsterdam, Netherlands.

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http://dx.doi.org/10.1128/IAI.00009-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191980PMC
July 2011

Targeting glycan modified OVA to murine DC-SIGN transgenic dendritic cells enhances MHC class I and II presentation.

Mol Immunol 2009 Dec 8;47(2-3):164-74. Epub 2009 Oct 8.

Department of Molecular Cell Biology and Immunology, VU Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2009.09.026DOI Listing
December 2009

TLR triggering on tolerogenic dendritic cells results in TLR2 up-regulation and a reduced proinflammatory immune program.

J Immunol 2009 Sep 31;183(5):2984-94. Epub 2009 Jul 31.

Department of Molecular Cell Biology and Immunology, Vrije University Medical Center, Amsterdam, The Netherlands.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0801155
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http://dx.doi.org/10.4049/jimmunol.0801155DOI Listing
September 2009

Interaction of polysialic acid with CCL21 regulates the migratory capacity of human dendritic cells.

PLoS One 2009 Sep 14;4(9):e6987. Epub 2009 Sep 14.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006987PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737307PMC
September 2009

Endogenous ligands for C-type lectin receptors: the true regulators of immune homeostasis.

Immunol Rev 2009 Jul;230(1):22-37

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1111/j.1600-065X.2009.00786.x
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http://dx.doi.org/10.1111/j.1600-065X.2009.00786.xDOI Listing
July 2009

Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses.

Immunol Cell Biol 2008 Oct 5;86(7):580-7. Epub 2008 Aug 5.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/icb.2008.55DOI Listing
October 2008

Nuclear targeting of beta-catenin and p120ctn during thrombin-induced endothelial barrier dysfunction.

Cardiovasc Res 2008 Sep 19;79(4):679-88. Epub 2008 May 19.

Department for Physiology, VU University Medical Center, Institute for Cardiovascular Research, van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvn127DOI Listing
September 2008

Glycan modification of the tumor antigen gp100 targets DC-SIGN to enhance dendritic cell induced antigen presentation to T cells.

Int J Cancer 2008 Feb;122(4):839-46

Department of Molecular Cell Biology and Immunology, VU Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/ijc.23101DOI Listing
February 2008

Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins.

J Immunol 2007 Dec;179(12):8216-24

Department of Molecular Cell Biology and Immunology, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.179.12.8216DOI Listing
December 2007

The glycosylation of thymic microenvironments. A microscopic study using plant lectins.

Immunol Lett 2007 May 17;110(1):65-73. Epub 2007 Apr 17.

Department of Molecular Cell Biology & Immunology, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.imlet.2007.03.005DOI Listing
May 2007

Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation.

Mol Immunol 2007 Apr 22;44(10):2605-15. Epub 2007 Jan 22.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S016158900600731
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http://dx.doi.org/10.1016/j.molimm.2006.12.012DOI Listing
April 2007

Gene expression analysis of glycosylation-related genes by real-time polymerase chain reaction.

Methods Mol Biol 2006 ;347:187-209

Department of Molecular Cell Biology and Immunology, Free University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1385/1-59745-167-3:187DOI Listing
January 2007

Specificity of DC-SIGN for mannose- and fucose-containing glycans.

FEBS Lett 2006 Nov 16;580(26):6123-31. Epub 2006 Oct 16.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Van der Boechorstsraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.febslet.2006.10.009DOI Listing
November 2006

Recognition of tumor glycans by antigen-presenting cells.

Curr Opin Immunol 2006 Feb 21;18(1):105-11. Epub 2005 Nov 21.

Department of Molecular Cell Biology and Immunology, Vrije Universiteit Medical Center Amsterdam, PO Box 7057, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.coi.2005.11.001DOI Listing
February 2006

Tumor necrosis factor-alpha up-regulates the expression of beta1,4-galactosyltransferase I in primary human endothelial cells by mRNA stabilization.

J Biol Chem 2005 Apr 24;280(13):12676-82. Epub 2005 Jan 24.

Department of Molecular Cell Biology and Immunology, Vrije Universiteit Medical Centre, 1007 MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M410093200DOI Listing
April 2005

Detection and removal of fat particles from postoperative salvaged blood in orthopedic surgery.

Transfusion 2002 Jan;42(1):66-75

International Multidisciplinary Autotransfusion Study Group (GIEMSA), Department of Hematology, University Hospital Virgen de la Victoria, School of Medicine, University of Málaga, 29071-Málaga, Spain.

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January 2002