Juan Carlos Souto

Juan Carlos Souto

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Juan Carlos Souto

Juan Carlos Souto

Publications by authors named "Juan Carlos Souto"

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58Publications

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Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Circulation 2019 01;139(5):620-635

Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438386PMC
January 2019

Short closure time values in PFA-100® are related to venous thrombotic risk. Results from the RETROVE Study.

Thromb Res 2018 09 11;169:57-63. Epub 2018 Jul 11.

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.07.012DOI Listing
September 2018

Erytrocyte-related phenotypes and genetic susceptibility to thrombosis.

Blood Cells Mol Dis 2016 07 13;59:44-8. Epub 2016 Apr 13.

Thrombosis and Hemostasis Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcmd.2016.04.006DOI Listing
July 2016

Age and gender effects on 15 platelet phenotypes in a Spanish population.

Comput Biol Med 2016 Feb 1;69:226-33. Epub 2016 Jan 1.

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, 167, Barcelona 08025, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2015.12.023DOI Listing
February 2016

Genetic determinants of platelet large-cell ratio, immature platelet fraction, and other platelet-related phenotypes.

Thromb Res 2015 Aug 17;136(2):361-6. Epub 2015 Jun 17.

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2015.06.016DOI Listing
August 2015

Cost-effectiveness analysis of dabigatran and anticoagulation monitoring strategies of vitamin K antagonist.

BMC Health Serv Res 2015 Jul 28;15:289. Epub 2015 Jul 28.

Department of Clinical Epidemiology & Biostatistics, CLARITY Research Group, McMaster University Medical Centre 2C9, 1200 Main St W, Hamilton, ON, Canada.

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http://dx.doi.org/10.1186/s12913-015-0934-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515878PMC
July 2015

A genomewide study of body mass index and its genetic correlation with thromboembolic risk. Results from the GAIT project.

Thromb Haemost 2014 Nov 14;112(5):1036-43. Epub 2014 Aug 14.

Juan Carlos Souto, MD, PhD, Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025, Barcelona, Spain, Tel.: +34 93 5537151, Fax: +34 93 5537153, E-mail:

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http://dx.doi.org/10.1160/TH14-03-0275DOI Listing
November 2014

Multilocus genetic risk scores for venous thromboembolism risk assessment.

J Am Heart Assoc 2014 Oct 23;3(5):e001060. Epub 2014 Oct 23.

Grupo de Epidemiología y, Genética Cardiovascular, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain (J.V., R.E.).

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http://dx.doi.org/10.1161/JAHA.114.001060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323784PMC
October 2014

A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels.

Mitochondrion 2014 Sep 18;18:34-40. Epub 2014 Sep 18.

Unit of Genomic of Complex Diseases, Research Institute of Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.mito.2014.09.004DOI Listing
September 2014

Genetic determinants of 5-lipoxygenase pathway in a Spanish population and their relationship with cardiovascular risk.

Atherosclerosis 2012 Sep 13;224(1):129-35. Epub 2012 Jul 13.

Laboratory of Angiology, Vascular Biology and Inflammation, Institute of Biomedical Research (II-B Sant Pau), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.07.001DOI Listing
September 2012

A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI Level and activated partial thromboplastin time.

Arterioscler Thromb Vasc Biol 2012 Aug 14;32(8):2008-16. Epub 2012 Jun 14.

Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1161/ATVBAHA.112.248492DOI Listing
August 2012

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

J Am Coll Cardiol 2012 Aug;60(8):722-9

Population Genomics, deCODE Genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.jacc.2012.01.078DOI Listing
August 2012

Predicting individual risk of venous thrombosis.

Blood 2012 Jul;120(3):500-1

IIB-Sant Pau.

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http://dx.doi.org/10.1182/blood-2012-06-433243DOI Listing
July 2012

Polymorphonuclear neutrophils and cancer: intense and sustained neutrophilia as a treatment against solid tumors.

Med Res Rev 2011 May;31(3):311-63

Department of Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1002/med.20185DOI Listing
May 2011

Disproportionation of rosin on an industrial Pd/C catalyst: reaction pathway and kinetic model discrimination.

Bioresour Technol 2011 Feb 12;102(3):3504-11. Epub 2010 Nov 12.

Departamento Ingeniería Química, Facultad CC Químicas, Universidad Complutense, Madrid, Spain.

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http://dx.doi.org/10.1016/j.biortech.2010.11.022DOI Listing
February 2011

Sequence variation and genetic evolution at the human F12 locus: mapping quantitative trait nucleotides that influence FXII plasma levels.

Hum Mol Genet 2010 Feb 23;19(3):517-25. Epub 2009 Nov 23.

Departament de Ciències Experimentals i de la Salut, Institute of Evolutionary Biology (UPF-CSIC), Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1093/hmg/ddp517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798724PMC
February 2010

Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels.

Eur J Hum Genet 2008 Nov 18;16(11):1372-9. Epub 2008 Jun 18.

Department of Hematology, Haemostasis and Thrombosis Unit, Hospital de la Santa Creu i Sant Pau, C/Sant Antoni Maria Claret 167, Barcelona, Spain.

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http://www.nature.com/articles/ejhg2008114
Publisher Site
http://dx.doi.org/10.1038/ejhg.2008.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749722PMC
November 2008

A genome-wide exploration suggests an oligogenic model of inheritance for the TAFI activity and its antigen levels.

Hum Genet 2008 Aug 18;124(1):81-8. Epub 2008 Jun 18.

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, C/Sant Antoni M.Claret 167. 08025, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00439-008-0527-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592198PMC
August 2008

Clustering of individuals given SNPs similarity based on normalized mutual information: F7 SNPs in the GAIT sample.

Conf Proc IEEE Eng Med Biol Soc 2007 ;2007:123-6

Centre de Recerca en Enginyeria Biomedica, Dept. d'Eng. Sistemes i Automatica Industrial, Universitat Politecnica de Catalunya, Pau Gargallo, 5, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1109/IEMBS.2007.4352238DOI Listing
March 2008

Plasma homocysteine and the genetics of cardiovascular disease.

Future Cardiol 2006 Mar;2(2):169-78

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Sant Antoni M feminine Claret 167, 08025 Barcelona, Spain.

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http://dx.doi.org/10.2217/14796678.2.2.169DOI Listing
March 2006

The F7 gene and clotting factor VII levels: dissection of a human quantitative trait locus.

Hum Biol 2005 Oct;77(5):561-75

Unitat d'Hemostasia i Trombosi, Departament d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1353/hub.2006.0006DOI Listing
October 2005

A genome search for genetic determinants that influence plasma fibrinogen levels.

Arterioscler Thromb Vasc Biol 2005 Jun 10;25(6):1287-92. Epub 2005 Mar 10.

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1161/01.ATV.0000161927.38739.6fDOI Listing
June 2005

Double heterozygosity for Factor V Leiden and Factor V Cambridge mutations associated with low levels of activated protein C resistance in a Spanish thrombophilic family.

Thromb Haemost 2005 Jun;93(6):1193-5

Hemostasis and Thrombosis Unit, Department of Hematology, Hospital de la Santa Creu i Sant Pau, C/ Sant Antoni Ma Claret, 167, 08025-Barcelona, Spain.

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June 2005

Heritability of hemostasis phenotypes and their correlation with type 2 diabetes status in Mexican Americans.

Hum Biol 2005 Feb;77(1):1-15

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA.

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http://dx.doi.org/10.1353/hub.2005.0034DOI Listing
February 2005

Protein C levels are regulated by a quantitative trait locus on chromosome 16: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project.

Arterioscler Thromb Vasc Biol 2004 Jul 13;24(7):1321-5. Epub 2004 May 13.

Unitat d'Hemostàsia i Trombosi, Departament d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1161/01.ATV.0000132408.13064.09DOI Listing
July 2004

Association after linkage analysis indicates that homozygosity for the 46C-->T polymorphism in the F12 gene is a genetic risk factor for venous thrombosis.

Thromb Haemost 2004 May;91(5):899-904

Unitat d'Hemostasi i Trombosi, Departament d'Hematologia, Hospital de la Santa Creu i Sant Pau, C/ Sant Antoni Ma Claret, 167. 08025, Barcelona, Spain.

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http://dx.doi.org/10.1160/TH03-10-0620DOI Listing
May 2004

Fondaparinux (ARIXTRA) as an alternative anti-thrombotic prophylaxis when there is hypersensitivity to low molecular weight and unfractionated heparins.

Haematologica 2003 Nov;88(11):ECR32

Unitat d'Hemòstasia i Trombosi. Hospital de la Santa Creu i Sant Pau. Barcelona, Spain.

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November 2003

Search for new thrombosis-related genes through intermediate phenotypes. Genetic and household effects.

Pathophysiol Haemost Thromb 2002 Sep-Dec;32(5-6):338-40

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1159/000073593DOI Listing
October 2003

Genome-wide linkage analysis of von Willebrand factor plasma levels: results from the GAIT project.

Thromb Haemost 2003 Mar;89(3):468-74

Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Barcelona. Spain.

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March 2003

Thromboplastin-thrombomodulin-mediated time and serum folate levels are genetically correlated with the risk of thromboembolic disease: results from the GAIT project.

Thromb Haemost 2002 Jan;87(1):68-73

Unitat d'Hemostàsia i Trombosi, Departament d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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January 2002