Juan Cadiñanos

Juan Cadiñanos

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Juan Cadiñanos

Juan Cadiñanos

Publications by authors named "Juan Cadiñanos"

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36Publications

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A novel molecular diagnostics platform for somatic and germline precision oncology.

Mol Genet Genomic Med 2017 Jul 23;5(4):336-359. Epub 2017 Apr 23.

Instituto de Medicina Oncológica y Molecular de Asturias (IMOMA) S. A.Avda. Richard Grandío s/n33193OviedoSpain.

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http://dx.doi.org/10.1002/mgg3.291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511795PMC
July 2017

Disentangling -cooperating tumor suppressor gene networks in cancer.

Mol Cell Oncol 2017 4;4(4):e1325550. Epub 2017 May 4.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, UK.

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http://dx.doi.org/10.1080/23723556.2017.1325550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540202PMC
May 2017

Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas.

Nat Commun 2013 ;4:2531

1] Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo 33006, Spain [2].

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http://dx.doi.org/10.1038/ncomms3531DOI Listing
May 2014

Novel germline CDKN2A mutation associated with head and neck squamous cell carcinomas and melanomas.

Head Neck 2013 Mar 15;35(3):E80-4. Epub 2011 Nov 15.

Instituto de Medicina Oncológica y Molecular de Asturias, Asturias, Spain.

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http://dx.doi.org/10.1002/hed.21911DOI Listing
March 2013

Novel germline SDHD deletion associated with an unusual sympathetic head and neck paraganglioma.

Head Neck 2011 Aug 22;33(8):1233-40. Epub 2010 Mar 22.

Instituto de Medicina Oncológica y Molecular de Asturias, Asturias, Spain.

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http://dx.doi.org/10.1002/hed.21384DOI Listing
August 2011

Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.

EMBO J 2011 Jun 26;30(11):2219-32. Epub 2011 Apr 26.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1038/emboj.2011.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117645PMC
June 2011

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.

Nature 2011 Jan 28;469(7328):102-6. Epub 2010 Nov 28.

Belfer Institute for Applied Cancer Science and Departments of Medical Oncology, Medicine and Genetics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature09603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057569PMC
January 2011

Premature aging in mice activates a systemic metabolic response involving autophagy induction.

Hum Mol Genet 2008 Jul 28;17(14):2196-211. Epub 2008 Apr 28.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1093/hmg/ddn120DOI Listing
July 2008

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Nat Med 2008 Jul 29;14(7):767-72. Epub 2008 Jun 29.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, calle Fernando, Bongera s/n, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1038/nm1786DOI Listing
July 2008

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice.

J Cell Biol 2008 Apr 31;181(1):27-35. Epub 2008 Mar 31.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://jcb.rupress.org/content/181/1/27.full.pdf
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http://www.jcb.org/lookup/doi/10.1083/jcb.200801096
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http://dx.doi.org/10.1083/jcb.200801096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287278PMC
April 2008

Generation of an inducible and optimized piggyBac transposon system.

Nucleic Acids Res 2007 18;35(12):e87. Epub 2007 Jun 18.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK.

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http://dx.doi.org/10.1093/nar/gkm446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919496PMC
August 2007

From immature lamin to premature aging: molecular pathways and therapeutic opportunities.

Cell Cycle 2005 Dec 23;4(12):1732-5. Epub 2005 Dec 23.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.4161/cc.4.12.2202DOI Listing
December 2005

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

Nature 2005 Sep 3;437(7058):564-8. Epub 2005 Aug 3.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1038/nature04019DOI Listing
September 2005

AtFACE-2, a functional prenylated protein protease from Arabidopsis thaliana related to mammalian Ras-converting enzymes.

J Biol Chem 2003 Oct 19;278(43):42091-7. Epub 2003 Aug 19.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Campus del Christo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1074/jbc.M306700200DOI Listing
October 2003

Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans.

Biochem J 2003 Mar;370(Pt 3):1047-54

Departamento de Bioqumica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Campus del Cristo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1042/BJ20021514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223240PMC
March 2003

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

Nat Genet 2002 May 1;31(1):94-9. Epub 2002 Apr 1.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://www.nature.com/articles/ng871
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http://dx.doi.org/10.1038/ng871DOI Listing
May 2002