Publications Authored by Joyce B van Meurs

Validated inference of smoking habits from blood with a finite DNA methylation marker set.

Eur J Epidemiol 2019 Nov 7;34(11):1055-1074. Epub 2019 Sep 7.

Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1007/s10654-019-00555-w	DOI Listing

November 2019

Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies.

Authors:

Jeroen van Rooij Pooja R Mandaviya Annique Claringbould Janine F Felix Jenny van Dongen Rick Jansen Lude Franke Peter A C 't Hoen Bas Heijmans Joyce B J van Meurs

Genome Biol 2019 Nov 14;20(1):235. Epub 2019 Nov 14.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/s13059-019-1878-x	DOI Listing

November 2019

Intestinal microbiome composition and its relation to joint pain and inflammation.

Authors:

Cindy G Boer Djawad Radjabzadeh Carolina Medina-Gomez Sanzhima Garmaeva Dieuwke Schiphof Pascal Arp Thomas Koet Alexander Kurilshikov Jingyuan Fu M Arfan Ikram Sita Bierma-Zeinstra André G Uitterlinden Robert Kraaij Alexandra Zhernakova Joyce B J van Meurs

Nat Commun 2019 Oct 25;10(1):4881. Epub 2019 Oct 25.

Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/s41467-019-12873-4	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814863	PMC

October 2019

Altered DNA methylation in children born to mothers with rheumatoid arthritis during pregnancy.

Authors:

Hilal Ince-Askan Pooja R Mandaviya Janine F Felix Liesbeth Duijts Joyce B van Meurs Johanna M W Hazes Radboud J E M Dolhain

Ann Rheum Dis 2019 Sep 29;78(9):1198-1204. Epub 2019 May 29.

Department of Rheumatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21493	Publisher Site
http://dx.doi.org/10.1136/annrheumdis-2018-214930	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788924	PMC

September 2019

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals.

Am J Clin Nutr 2019 Aug;110(2):437-450

Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1093/ajcn/nqz031	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669135	PMC

August 2019

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

Authors:

Jun Liu Elena Carnero-Montoro Jenny van Dongen Samantha Lent Ivana Nedeljkovic Symen Ligthart Pei-Chien Tsai Tiphaine C Martin Pooja R Mandaviya Rick Jansen Marjolein J Peters Liesbeth Duijts Vincent W V Jaddoe Henning Tiemeier Janine F Felix Gonneke Willemsen Eco J C de Geus Audrey Y Chu Daniel Levy Shih-Jen Hwang Jan Bressler Rahul Gondalia Elias L Salfati Christian Herder Bertha A Hidalgo Toshiko Tanaka Ann Zenobia Moore Rozenn N Lemaitre Min A Jhun Jennifer A Smith Nona Sotoodehnia Stefania Bandinelli Luigi Ferrucci Donna K Arnett Harald Grallert Themistocles L Assimes Lifang Hou Andrea Baccarelli Eric A Whitsel Ko Willems van Dijk Najaf Amin André G Uitterlinden Eric J G Sijbrands Oscar H Franco Abbas Dehghan Tim D Spector Josée Dupuis Marie-France Hivert Jerome I Rotter James B Meigs James S Pankow Joyce B J van Meurs Aaron Isaacs Dorret I Boomsma Jordana T Bell Ayşe Demirkan Cornelia M van Duijn

Nat Commun 2019 06 13;10(1):2581. Epub 2019 Jun 13.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/s41467-019-10487-4	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565679	PMC

June 2019

Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer.

Authors:

Fleur S Peters Annemiek M A Peeters Pooja R Mandaviya Joyce B J van Meurs Leo J Hofland Jacqueline van de Wetering Michiel G H Betjes Carla C Baan Karin Boer

Clin Epigenetics 2018 18;10:81. Epub 2018 Jun 18.

1Neprology and Transplantation, Department of Internal Medicine, Rotterdam Transplant Group, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/s13148-018-0519-7	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006560	PMC

May 2019

A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease.

Diabetes 2019 05 1;68(5):1073-1083. Epub 2019 Apr 1.

Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, and Framingham Heart Study, Framingham, MA

View Article

Download full-text PDF	Source
http://dx.doi.org/10.2337/DB18-1193	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477898	PMC

May 2019

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course.

Eur Respir J 2019 Apr 4;53(4). Epub 2019 Apr 4.

Dept of Pediatrics, Division of Respiratory Medicine and Allergology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1183/13993003.01795-2018	DOI Listing

April 2019

Are Bone Mineral Density and Fractures Related to the Incidence and Progression of Radiographic Osteoarthritis of the Knee, Hip, and Hand in Elderly Men and Women? The Rotterdam Study.

Authors:

Arjan P Bergink Fernando Rivadeneira Sita M Bierma-Zeinstra M Carola Zillikens M Arfan Ikram André G Uitterlinden Joyce B J van Meurs

Arthritis Rheumatol 2019 03 9;71(3):361-369. Epub 2019 Feb 9.

Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1002/art.40735	DOI Listing

March 2019

Dissecting the association of autophagy-related genes with cardiovascular diseases and intermediate vascular traits: A population-based approach.

Authors:

Eliana Portilla-Fernandez Mohsen Ghanbari Joyce B J van Meurs A H Jan Danser Oscar H Franco Taulant Muka Anton Roks Abbas Dehghan

PLoS One 2019 25;14(3):e0214137. Epub 2019 Mar 25.

Department of Epidemiology and Biostatistics, Imperial College London, London, England.

View Article

Download full-text PDF	Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214137	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433264	PMC

March 2019

Whole Blood Gene Expression Associated With Clinical Biological Age.

Authors:

Honghuang Lin Kathryn L Lunetta Qiang Zhao Pooja R Mandaviya Jian Rong Emelia J Benjamin Roby Joehanes Daniel Levy Joyce B J van Meurs Martin G Larson Joanne M Murabito

J Gerontol A Biol Sci Med Sci 2019 01;74(1):81-88

National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Massachusetts.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1093/gerona/gly164	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298179	PMC

January 2019

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults.

Authors:

Priyanka Parmar Estelle Lowry Giovanni Cugliari Matthew Suderman Rory Wilson Ville Karhunen Toby Andrew Petri Wiklund Matthias Wielscher Simonetta Guarrera Alexander Teumer Benjamin Lehne Lili Milani Niek de Klein Pashupati P Mishra Phillip E Melton Pooja R Mandaviya Silva Kasela Jana Nano Weihua Zhang Yan Zhang Andre G Uitterlinden Annette Peters Ben Schöttker Christian Gieger Denise Anderson Dorret I Boomsma Hans J Grabe Salvatore Panico Jan H Veldink Joyce B J van Meurs Leonard van den Berg Lawrence J Beilin Lude Franke Marie Loh Marleen M J van Greevenbroek Matthias Nauck Mika Kähönen Mikko A Hurme Olli T Raitakari Oscar H Franco P Eline Slagboom Pim van der Harst Sonja Kunze Stephan B Felix Tao Zhang Wei Chen Trevor A Mori Amelie Bonnefond Bastiaan T Heijmans Taulant Muka Jaspal S Kooner Krista Fischer Melanie Waldenberger Philippe Froguel Rae-Chi Huang Terho Lehtimäki Wolfgang Rathmann Caroline L Relton Giuseppe Matullo Hermann Brenner Niek Verweij Shengxu Li John C Chambers Marjo-Riitta Järvelin Sylvain Sebert

EBioMedicine 2018 Dec 13;38:206-216. Epub 2018 Nov 13.

Center for Life Course Health Research, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Medical Research Centre (MRC) Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland. Electronic address:

View Article

Download full-text PDF	Source
https://linkinghub.elsevier.com/retrieve/pii/S23523964183048	Publisher Site
http://dx.doi.org/10.1016/j.ebiom.2018.10.066	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306313	PMC

December 2018

Meta-analysis of epigenome-wide association studies of cognitive abilities.

Mol Psychiatry 2018 11 8;23(11):2133-2144. Epub 2018 Jan 8.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/s41380-017-0008-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035894	PMC

November 2018

DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis.

Authors:

Cavin K Ward-Caviness Jennifer E Huffman Karl Everett Marine Germain Jenny van Dongen W David Hill Min A Jhun Jennifer A Brody Mohsen Ghanbari Lei Du Nicholas S Roetker Paul S de Vries Melanie Waldenberger Christian Gieger Petra Wolf Holger Prokisch Wolfgang Koenig Christopher J O'Donnell Daniel Levy Chunyu Liu Vinh Truong Philip S Wells David-Alexandre Trégouët Weihong Tang Alanna C Morrison Eric Boerwinkle Kerri L Wiggins Barbara McKnight Xiuqing Guo Bruce M Psaty Nona Sotoodenia Dorret I Boomsma Gonneke Willemsen Lannie Ligthart Ian J Deary Wei Zhao Erin B Ware Sharon L R Kardia Joyce B J Van Meurs Andre G Uitterlinden Oscar H Franco Per Eriksson Anders Franco-Cereceda James S Pankow Andrew D Johnson France Gagnon Pierre-Emmanuel Morange Eco J C de Geus John M Starr Jennifer A Smith Abbas Dehghan Hanna M Björck Nicholas L Smith Annette Peters

Blood 2018 10 24;132(17):1842-1850. Epub 2018 Jul 24.

Institute of Epidemiology II, Helmholtz Center of Munich, Neuherberg, Germany.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1182/blood-2018-02-831347	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202911	PMC

October 2018

Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain.

PLoS Genet 2018 09 27;14(9):e1007601. Epub 2018 Sep 27.

Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1371/journal.pgen.1007601	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159857	PMC

September 2018

An Epigenome-Wide Association Study of Obesity-Related Traits.

Authors:

Klodian Dhana Kim V E Braun Jana Nano Trudy Voortman Ellen W Demerath Weihua Guan Myriam Fornage Joyce B J van Meurs Andre G Uitterlinden Albert Hofman Oscar H Franco Abbas Dehghan

Am J Epidemiol 2018 08;187(8):1662-1669

Department of Epidemiology, Erasmus University Medical Center.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1093/aje/kwy025	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070087	PMC

August 2018

Epigenetic changes in umbilical cord mesenchymal stromal cells upon stimulation and culture expansion.

Authors:

Samantha F H De Witte Fleur S Peters Ana Merino Sander S Korevaar Joyce B J Van Meurs Lisa O'Flynn Steve J Elliman Philip N Newsome Karin Boer Carla C Baan Martin J Hoogduijn

Cytotherapy 2018 07 20;20(7):919-929. Epub 2018 Jun 20.

Nephrology and Transplantation. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.jcyt.2018.05.005	DOI Listing

July 2018

Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α.

JAMA Cardiol 2018 06;3(6):463-472

College of Public Health, University of Kentucky, Lexington.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1001/jamacardio.2018.0510	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100733	PMC

June 2018

A systematic analysis highlights multiple long non-coding RNAs associated with cardiometabolic disorders.

Authors:

Mohsen Ghanbari Marjolein J Peters Paul S de Vries Cindy G Boer Jeroen G J van Rooij Yu-Chi Lee Vinod Kumar André G Uitterlinden M Arfan Ikram Cisca Wijmenga Jose M Ordovas Caren E Smith Joyce B J van Meurs Stefan J Erkeland Oscar H Franco Abbas Dehghan

J Hum Genet 2018 Apr 30;63(4):431-446. Epub 2018 Jan 30.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/s10038-017-0403-x	DOI Listing

April 2018

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

Nat Genet 2018 04 20;50(4):549-558. Epub 2018 Mar 20.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/s41588-018-0079-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896734	PMC

April 2018

DNA methylation signatures of educational attainment.

Authors:

Jenny van Dongen Marc Jan Bonder Koen F Dekkers Michel G Nivard Maarten van Iterson Gonneke Willemsen Marian Beekman Ashley van der Spek Joyce B J van Meurs Lude Franke Bastiaan T Heijmans Cornelia M van Duijn P Eline Slagboom Dorret I Boomsma

NPJ Sci Learn 2018 23;3. Epub 2018 Mar 23.

1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/s41539-018-0020-2	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220239	PMC

March 2018

COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression.

Hum Mol Genet 2018 01;27(2):396-405

Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1093/hmg/ddx390	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886099	PMC

January 2018

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.

Authors:

Melissa A Richard Tianxiao Huan Symen Ligthart Rahul Gondalia Min A Jhun Jennifer A Brody Marguerite R Irvin Riccardo Marioni Jincheng Shen Pei-Chien Tsai May E Montasser Yucheng Jia Catriona Syme Elias L Salfati Eric Boerwinkle Weihua Guan Thomas H Mosley Jan Bressler Alanna C Morrison Chunyu Liu Michael M Mendelson André G Uitterlinden Joyce B van Meurs Oscar H Franco Guosheng Zhang Yun Li James D Stewart Joshua C Bis Bruce M Psaty Yii-Der Ida Chen Sharon L R Kardia Wei Zhao Stephen T Turner Devin Absher Stella Aslibekyan John M Starr Allan F McRae Lifang Hou Allan C Just Joel D Schwartz Pantel S Vokonas Cristina Menni Tim D Spector Alan Shuldiner Coleen M Damcott Jerome I Rotter Walter Palmas Yongmei Liu Tomáš Paus Steve Horvath Jeffrey R O'Connell Xiuqing Guo Zdenka Pausova Themistocles L Assimes Nona Sotoodehnia Jennifer A Smith Donna K Arnett Ian J Deary Andrea A Baccarelli Jordana T Bell Eric Whitsel Abbas Dehghan Daniel Levy Myriam Fornage

Am J Hum Genet 2017 Dec 30;101(6):888-902. Epub 2017 Nov 30.

Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA; Human Genetics Center, School of Public Health, University of Texas Health Science Center, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.ajhg.2017.09.028	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812919	PMC

December 2017

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes.

PLoS One 2017 30;12(10):e0182472. Epub 2017 Oct 30.

Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182472	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662081	PMC

November 2017

Epigenome-Wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis.

Authors:

Jana Nano Mohsen Ghanbari Wenshi Wang Paul S de Vries Klodian Dhana Taulant Muka André G Uitterlinden Joyce B J van Meurs Albert Hofman Oscar H Franco Qiuwei Pan Sarwa Darwish Murad Abbas Dehghan

Gastroenterology 2017 10 15;153(4):1096-1106.e2. Epub 2017 Jun 15.

Department of Biostatistics and Epidemiology, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1053/j.gastro.2017.06.003	DOI Listing

October 2017

Population-specific genetic variation in large sequencing data sets: why more data is still better.

Authors:

Jeroen G J van Rooij Mila Jhamai Pascal P Arp Stephan C A Nouwens Marijn Verkerk Albert Hofman M Arfan Ikram Annemieke J Verkerk Joyce B J van Meurs Fernando Rivadeneira André G Uitterlinden Robert Kraaij

Eur J Hum Genet 2017 10 19;25(10):1173-1175. Epub 2017 Jul 19.

Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ejhg.2017.110	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602011	PMC

October 2017

Early- and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn.

Authors:

Emilie M Herzog Alex J Eggink Sten P Willemsen Roderick C Slieker Kim P J Wijnands Janine F Felix Jun Chen Andrew Stubbs Peter J van der Spek Joyce B van Meurs Régine P M Steegers-Theunissen

Placenta 2017 Oct 30;58:122-132. Epub 2017 Aug 30.

Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre Rotterdam, Postbus 2040, 3000 CA Rotterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.placenta.2017.08.070	DOI Listing

October 2017

Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity.

Authors:

George L Sutphin Grant Backer Susan Sheehan Shannon Bean Caroline Corban Teresa Liu Marjolein J Peters Joyce B J van Meurs Joanne M Murabito Andrew D Johnson Ron Korstanje

Aging Cell 2017 08 12;16(4):672-682. Epub 2017 Apr 12.

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1111/acel.12595	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506438	PMC

August 2017

Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study.

Authors:

Kim V E Braun Klodian Dhana Paul S de Vries Trudy Voortman Joyce B J van Meurs Andre G Uitterlinden Albert Hofman Frank B Hu Oscar H Franco Abbas Dehghan

Clin Epigenetics 2017 7;9:15. Epub 2017 Feb 7.

Department of Epidemiology, Erasmus University Medical Center, Dr. Molewaterplein 50, Office NA2906, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/s13148-016-0304-4	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297218	PMC

July 2017

Asymptomatic radiographic hip osteoarthritis is associated with gait differences, especially in women: A population-based study.

Authors:

Vincentius J A Verlinden Marjolein de Kruijf Sita M A Bierma-Zeinstra Albert Hofman André G Uitterlinden M Arfan Ikram Joyce B J van Meurs Jos N van der Geest

Gait Posture 2017 05 16;54:248-254. Epub 2017 Mar 16.

Department of Neuroscience, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.gaitpost.2017.03.009	DOI Listing

May 2017

Cam Deformity and Acetabular Dysplasia as Risk Factors for Hip Osteoarthritis.

Authors:

Fatemeh Saberi Hosnijeh Maria E Zuiderwijk Mathijs Versteeg Hieronymus T W Smeele Albert Hofman André G Uitterlinden Rintje Agricola Edwin H G Oei Jan H Waarsing Sita M Bierma-Zeinstra Joyce B J van Meurs

Arthritis Rheumatol 2017 01 2;69(1):86-93. Epub 2016 Dec 2.

Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1002/art.39929	DOI Listing

January 2017

Identification of context-dependent expression quantitative trait loci in whole blood.

Nat Genet 2017 01 5;49(1):139-145. Epub 2016 Dec 5.

University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ng.3737	DOI Listing

January 2017

Disease variants alter transcription factor levels and methylation of their binding sites.

Authors:

Marc Jan Bonder René Luijk Daria V Zhernakova Matthijs Moed Patrick Deelen Martijn Vermaat Maarten van Iterson Freerk van Dijk Michiel van Galen Jan Bot Roderick C Slieker P Mila Jhamai Michael Verbiest H Eka D Suchiman Marijn Verkerk Ruud van der Breggen Jeroen van Rooij Nico Lakenberg Wibowo Arindrarto Szymon M Kielbasa Iris Jonkers Peter van 't Hof Irene Nooren Marian Beekman Joris Deelen Diana van Heemst Alexandra Zhernakova Ettje F Tigchelaar Morris A Swertz Albert Hofman André G Uitterlinden René Pool Jenny van Dongen Jouke J Hottenga Coen D A Stehouwer Carla J H van der Kallen Casper G Schalkwijk Leonard H van den Berg Erik W van Zwet Hailiang Mei Yang Li Mathieu Lemire Thomas J Hudson P Eline Slagboom Cisca Wijmenga Jan H Veldink Marleen M J van Greevenbroek Cornelia M van Duijn Dorret I Boomsma Aaron Isaacs Rick Jansen Joyce B J van Meurs Peter A C 't Hoen Lude Franke Bastiaan T Heijmans

Nat Genet 2017 01 5;49(1):131-138. Epub 2016 Dec 5.

Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ng.3721	DOI Listing

January 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Authors:

Simone Wahl Alexander Drong Benjamin Lehne Marie Loh William R Scott Sonja Kunze Pei-Chien Tsai Janina S Ried Weihua Zhang Youwen Yang Sili Tan Giovanni Fiorito Lude Franke Simonetta Guarrera Silva Kasela Jennifer Kriebel Rebecca C Richmond Marco Adamo Uzma Afzal Mika Ala-Korpela Benedetta Albetti Ole Ammerpohl Jane F Apperley Marian Beekman Pier Alberto Bertazzi S Lucas Black Christine Blancher Marc-Jan Bonder Mario Brosch Maren Carstensen-Kirberg Anton J M de Craen Simon de Lusignan Abbas Dehghan Mohamed Elkalaawy Krista Fischer Oscar H Franco Tom R Gaunt Jochen Hampe Majid Hashemi Aaron Isaacs Andrew Jenkinson Sujeet Jha Norihiro Kato Vittorio Krogh Michael Laffan Christa Meisinger Thomas Meitinger Zuan Yu Mok Valeria Motta Hong Kiat Ng Zacharoula Nikolakopoulou Georgios Nteliopoulos Salvatore Panico Natalia Pervjakova Holger Prokisch Wolfgang Rathmann Michael Roden Federica Rota Michelle Ann Rozario Johanna K Sandling Clemens Schafmayer Katharina Schramm Reiner Siebert P Eline Slagboom Pasi Soininen Lisette Stolk Konstantin Strauch E-Shyong Tai Letizia Tarantini Barbara Thorand Ettje F Tigchelaar Rosario Tumino Andre G Uitterlinden Cornelia van Duijn Joyce B J van Meurs Paolo Vineis Ananda Rajitha Wickremasinghe Cisca Wijmenga Tsun-Po Yang Wei Yuan Alexandra Zhernakova Rachel L Batterham George Davey Smith Panos Deloukas Bastiaan T Heijmans Christian Herder Albert Hofman Cecilia M Lindgren Lili Milani Pim van der Harst Annette Peters Thomas Illig Caroline L Relton Melanie Waldenberger Marjo-Riitta Järvelin Valentina Bollati Richie Soong Tim D Spector James Scott Mark I McCarthy Paul Elliott Jordana T Bell Giuseppe Matullo Christian Gieger Jaspal S Kooner Harald Grallert John C Chambers

Nature 2017 01 21;541(7635):81-86. Epub 2016 Dec 21.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/nature20784	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570525	PMC

January 2017

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations.

Diabetes 2016 Dec 13;65(12):3794-3804. Epub 2016 Sep 13.

Program in Bioinformatics, Boston University, Boston, MA

View Article

Download full-text PDF	Source
http://dx.doi.org/10.2337/db16-0470	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127245	PMC

December 2016

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.

Authors:

Symen Ligthart Carola Marzi Stella Aslibekyan Michael M Mendelson Karen N Conneely Toshiko Tanaka Elena Colicino Lindsay L Waite Roby Joehanes Weihua Guan Jennifer A Brody Cathy Elks Riccardo Marioni Min A Jhun Golareh Agha Jan Bressler Cavin K Ward-Caviness Brian H Chen Tianxiao Huan Kelly Bakulski Elias L Salfati Giovanni Fiorito Simone Wahl Katharina Schramm Jin Sha Dena G Hernandez Allan C Just Jennifer A Smith Nona Sotoodehnia Luke C Pilling James S Pankow Phil S Tsao Chunyu Liu Wei Zhao Simonetta Guarrera Vasiliki J Michopoulos Alicia K Smith Marjolein J Peters David Melzer Pantel Vokonas Myriam Fornage Holger Prokisch Joshua C Bis Audrey Y Chu Christian Herder Harald Grallert Chen Yao Sonia Shah Allan F McRae Honghuang Lin Steve Horvath Daniele Fallin Albert Hofman Nicholas J Wareham Kerri L Wiggins Andrew P Feinberg John M Starr Peter M Visscher Joanne M Murabito Sharon L R Kardia Devin M Absher Elisabeth B Binder Andrew B Singleton Stefania Bandinelli Annette Peters Melanie Waldenberger Giuseppe Matullo Joel D Schwartz Ellen W Demerath André G Uitterlinden Joyce B J van Meurs Oscar H Franco Yii-Der Ida Chen Daniel Levy Stephen T Turner Ian J Deary Kerry J Ressler Josée Dupuis Luigi Ferrucci Ken K Ong Themistocles L Assimes Eric Boerwinkle Wolfgang Koenig Donna K Arnett Andrea A Baccarelli Emelia J Benjamin Abbas Dehghan

Genome Biol 2016 12 12;17(1):255. Epub 2016 Dec 12.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/s13059-016-1119-5	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151130	PMC

December 2016

Blood RNA expression profiles undergo major changes during the seventh decade.

Authors:

Marius Gheorghe Claudia Schurmann Marjolein J Peters André G Uitterlinden Albert Hofman Reiner Biffar Georg Homuth Uwe Völker Joyce B J van Meurs Vered Raz

Oncotarget 2016 Nov;7(44):71353-71361

Department of Human and Clinical Genetics, Leiden University Medical Centre, Leiden, 2300 RC, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.18632/oncotarget.12098	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342083	PMC

November 2016

A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking.

Hum Mol Genet 2016 11;25(21):4611-4623

Boston University’s Framingham Heart Study, Framingham, MA, USA.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1093/hmg/ddw288	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975607	PMC

November 2016

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.

PLoS Genet 2016 Oct 4;12(10):e1006260. Epub 2016 Oct 4.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1371/journal.pgen.1006260	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049763	PMC

October 2016

Epigenetic Signatures of Cigarette Smoking.

Authors:

Roby Joehanes Allan C Just Riccardo E Marioni Luke C Pilling Lindsay M Reynolds Pooja R Mandaviya Weihua Guan Tao Xu Cathy E Elks Stella Aslibekyan Hortensia Moreno-Macias Jennifer A Smith Jennifer A Brody Radhika Dhingra Paul Yousefi James S Pankow Sonja Kunze Sonia H Shah Allan F McRae Kurt Lohman Jin Sha Devin M Absher Luigi Ferrucci Wei Zhao Ellen W Demerath Jan Bressler Megan L Grove Tianxiao Huan Chunyu Liu Michael M Mendelson Chen Yao Douglas P Kiel Annette Peters Rui Wang-Sattler Peter M Visscher Naomi R Wray John M Starr Jingzhong Ding Carlos J Rodriguez Nicholas J Wareham Marguerite R Irvin Degui Zhi Myrto Barrdahl Paolo Vineis Srikant Ambatipudi André G Uitterlinden Albert Hofman Joel Schwartz Elena Colicino Lifang Hou Pantel S Vokonas Dena G Hernandez Andrew B Singleton Stefania Bandinelli Stephen T Turner Erin B Ware Alicia K Smith Torsten Klengel Elisabeth B Binder Bruce M Psaty Kent D Taylor Sina A Gharib Brenton R Swenson Liming Liang Dawn L DeMeo George T O'Connor Zdenko Herceg Kerry J Ressler Karen N Conneely Nona Sotoodehnia Sharon L R Kardia David Melzer Andrea A Baccarelli Joyce B J van Meurs Isabelle Romieu Donna K Arnett Ken K Ong Yongmei Liu Melanie Waldenberger Ian J Deary Myriam Fornage Daniel Levy Stephanie J London

Circ Cardiovasc Genet 2016 Oct 20;9(5):436-447. Epub 2016 Sep 20.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1161/CIRCGENETICS.116.001506	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267325	PMC

October 2016

Determinants for Quantitative Sensory Testing and the Association with Chronic Musculoskeletal Pain in the General Elderly Population.

Authors:

Marjolein de Kruijf Marjolein J Peters Leonie C Jacobs Henning Tiemeier Tamar Nijsten Albert Hofman Andre G Uitterlinden Frank J P M Huygen Joyce B J van Meurs

Pain Pract 2016 09 23;16(7):831-41. Epub 2015 Jul 23.

Department of Internal Medicine, Erasmus MC Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1111/papr.12335	DOI Listing

September 2016

Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length.

Authors:

Dmitry Zubakov Fan Liu Iris Kokmeijer Ying Choi Joyce B J van Meurs Wilfred F J van IJcken André G Uitterlinden Albert Hofman Linda Broer Cornelia M van Duijn Jörn Lewin Manfred Kayser

Forensic Sci Int Genet 2016 09 24;24:33-43. Epub 2016 May 24.

Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.fsigen.2016.05.014	DOI Listing

September 2016

Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition.

Authors:

Kristina Gervin Christian Magnus Page Hans Christian D Aass Michelle A Jansen Heidi Elisabeth Fjeldstad Bettina Kulle Andreassen Liesbeth Duijts Joyce B van Meurs Menno C van Zelm Vincent W Jaddoe Hedvig Nordeng Gunn Peggy Knudsen Per Magnus Wenche Nystad Anne Cathrine Staff Janine F Felix Robert Lyle

Epigenetics 2016 Sep;11(9):690-698

a Department of Medical Genetics , Oslo University Hospital , Oslo , Norway.

View Article

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048717	PMC
http://dx.doi.org/10.1080/15592294.2016.1214782	DOI Listing

September 2016

Lower sex hormone levels are associated with more chronic musculoskeletal pain in community-dwelling elderly women.

Authors:

Marjolein de Kruijf Lisette Stolk M Carola Zillikens Yolanda B de Rijke Sita M A Bierma-Zeinstra Albert Hofman Frank J P M Huygen Andre G Uitterlinden Joyce B J van Meurs

Pain 2016 07;157(7):1425-31

Departments of aInternal MedicinebAnaesthesiologycClinical ChemistrydGeneral Practice, Erasmus MCeOrthopedic Surgery, University Medical Center Rotterdam, the NetherlandsfEpidemiology, Erasmus MC, Rotterdam, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1097/j.pain.0000000000000535	DOI Listing

July 2016

Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes.

Authors:

Symen Ligthart Rebecca V Steenaard Marjolein J Peters Joyce B J van Meurs Eric J G Sijbrands André G Uitterlinden Marc J Bonder Albert Hofman Oscar H Franco Abbas Dehghan

Diabetologia 2016 May 29;59(5):998-1006. Epub 2016 Jan 29.

Department of Epidemiology, Erasmus University Medical Center, P. O. Box 2040, 3000 CA, Rotterdam, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1007/s00125-016-3872-0	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826423	PMC

May 2016

Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis.

Authors:

Marjolein J Peters Yolande F M Ramos Wouter den Hollander Dieuwke Schiphof Albert Hofman André G Uitterlinden Edwin H G Oei P Eline Slagboom Margreet Kloppenburg Johan L Bloem Sita M A Bierma-Zeinstra Ingrid Meulenbelt Joyce B J van Meurs

F1000Res 2016 27;5:109. Epub 2016 Jan 27.

Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.12688/f1000research.7763.1	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837985	PMC

May 2016

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure.

Authors:

J Gustav Smith Janine F Felix Alanna C Morrison Andreas Kalogeropoulos Stella Trompet Jemma B Wilk Olof Gidlöf Xinchen Wang Michael Morley Michael Mendelson Roby Joehanes Symen Ligthart Xiaoyin Shan Joshua C Bis Ying A Wang Marketa Sjögren Julius Ngwa Jeffrey Brandimarto David J Stott David Aguilar Kenneth M Rice Howard D Sesso Serkalem Demissie Brendan M Buckley Kent D Taylor Ian Ford Chen Yao Chunyu Liu Nona Sotoodehnia Pim van der Harst Bruno H Ch Stricker Stephen B Kritchevsky Yongmei Liu J Michael Gaziano Albert Hofman Christine S Moravec André G Uitterlinden Manolis Kellis Joyce B van Meurs Kenneth B Margulies Abbas Dehghan Daniel Levy Björn Olde Bruce M Psaty L Adrienne Cupples J Wouter Jukema Luc Djousse Oscar H Franco Eric Boerwinkle Laurie A Boyer Christopher Newton-Cheh Javed Butler Ramachandran S Vasan Thomas P Cappola Nicholas L Smith

PLoS Genet 2016 05 5;12(5):e1006034. Epub 2016 May 5.

Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1371/journal.pgen.1006034	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858216	PMC

May 2016

25-Hydroxyvitamin D and osteoarthritis: A meta-analysis including new data.

Authors:

Arjan P Bergink M Carola Zillikens Johannes P T M Van Leeuwen Albert Hofman André G Uitterlinden Joyce B J van Meurs

Semin Arthritis Rheum 2016 Apr 29;45(5):539-46. Epub 2015 Oct 29.

Departments of Internal Medicine, Genetic Laboratory, Erasmus Medical Center, Room Ee579b, PO Box 1738, Rotterdam 3000 DR, The Netherlands. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.semarthrit.2015.09.010	DOI Listing

April 2016

Association between biomarkers of tissue inflammation and progression of osteoarthritis: evidence from the Rotterdam study cohort.

Authors:

Fatemeh Saberi Hosnijeh Anne Sofie Siebuhr Andre G Uitterlinden Edwin H G Oei Albert Hofman Morten A Karsdal Sita M Bierma-Zeinstra Anne C Bay-Jensen Joyce B J van Meurs

Arthritis Res Ther 2016 Apr 1;18:81. Epub 2016 Apr 1.

Department of Internal Medicine, Erasmus University Medical Center, P.O. Box 2040, Rotterdam, 3000, CA, Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/s13075-016-0976-3	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818486	PMC

April 2016

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

Authors:

Bonnie R Joubert Janine F Felix Paul Yousefi Kelly M Bakulski Allan C Just Carrie Breton Sarah E Reese Christina A Markunas Rebecca C Richmond Cheng-Jian Xu Leanne K Küpers Sam S Oh Cathrine Hoyo Olena Gruzieva Cilla Söderhäll Lucas A Salas Nour Baïz Hongmei Zhang Johanna Lepeule Carlos Ruiz Symen Ligthart Tianyuan Wang Jack A Taylor Liesbeth Duijts Gemma C Sharp Soesma A Jankipersadsing Roy M Nilsen Ahmad Vaez M Daniele Fallin Donglei Hu Augusto A Litonjua Bernard F Fuemmeler Karen Huen Juha Kere Inger Kull Monica Cheng Munthe-Kaas Ulrike Gehring Mariona Bustamante Marie José Saurel-Coubizolles Bilal M Quraishi Jie Ren Jörg Tost Juan R Gonzalez Marjolein J Peters Siri E Håberg Zongli Xu Joyce B van Meurs Tom R Gaunt Marjan Kerkhof Eva Corpeleijn Andrew P Feinberg Celeste Eng Andrea A Baccarelli Sara E Benjamin Neelon Asa Bradman Simon Kebede Merid Anna Bergström Zdenko Herceg Hector Hernandez-Vargas Bert Brunekreef Mariona Pinart Barbara Heude Susan Ewart Jin Yao Nathanaël Lemonnier Oscar H Franco Michael C Wu Albert Hofman Wendy McArdle Pieter Van der Vlies Fahimeh Falahi Matthew W Gillman Lisa F Barcellos Ashish Kumar Magnus Wickman Stefano Guerra Marie-Aline Charles John Holloway Charles Auffray Henning W Tiemeier George Davey Smith Dirkje Postma Marie-France Hivert Brenda Eskenazi Martine Vrijheid Hasan Arshad Josep M Antó Abbas Dehghan Wilfried Karmaus Isabella Annesi-Maesano Jordi Sunyer Akram Ghantous Göran Pershagen Nina Holland Susan K Murphy Dawn L DeMeo Esteban G Burchard Christine Ladd-Acosta Harold Snieder Wenche Nystad Gerard H Koppelman Caroline L Relton Vincent W V Jaddoe Allen Wilcox Erik Melén Stephanie J London

Am J Hum Genet 2016 Apr 31;98(4):680-96. Epub 2016 Mar 31.

National Institute of Environmental Health Sciences, NIH, U.S. Department of Health and Human Services, Research Triangle Park, NC 27709, USA. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.ajhg.2016.02.019	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833289	PMC

April 2016

Genetic and environmental influences interact with age and sex in shaping the human methylome.

Authors:

Jenny van Dongen Michel G Nivard Gonneke Willemsen Jouke-Jan Hottenga Quinta Helmer Conor V Dolan Erik A Ehli Gareth E Davies Maarten van Iterson Charles E Breeze Stephan Beck H Eka Suchiman Rick Jansen Joyce B van Meurs Bastiaan T Heijmans P Eline Slagboom Dorret I Boomsma

Nat Commun 2016 Apr 7;7:11115. Epub 2016 Apr 7.

Department of Biological Psychology, VU Amsterdam, Van der Boechorststraat 1, 1081BT Amsterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ncomms11115	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820961	PMC

April 2016

Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.

Blood 2016 Mar 29;127(11):1512-5. Epub 2016 Jan 29.

Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands;

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1182/blood-2015-12-685925	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797027	PMC

March 2016

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns.

Nat Commun 2016 Feb 10;7:10577. Epub 2016 Feb 10.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ncomms10577	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749955	PMC

February 2016

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.

Authors:

Janine F Felix Jonathan P Bradfield Claire Monnereau Ralf J P van der Valk Evie Stergiakouli Alessandra Chesi Romy Gaillard Bjarke Feenstra Elisabeth Thiering Eskil Kreiner-Møller Anubha Mahajan Niina Pitkänen Raimo Joro Alana Cavadino Ville Huikari Steve Franks Maria M Groen-Blokhuis Diana L Cousminer Julie A Marsh Terho Lehtimäki John A Curtin Jesus Vioque Tarunveer S Ahluwalia Ronny Myhre Thomas S Price Natalia Vilor-Tejedor Loïc Yengo Niels Grarup Ioanna Ntalla Wei Ang Mustafa Atalay Hans Bisgaard Alexandra I Blakemore Amelie Bonnefond Lisbeth Carstensen Johan Eriksson Claudia Flexeder Lude Franke Frank Geller Mandy Geserick Anna-Liisa Hartikainen Claire M A Haworth Joel N Hirschhorn Albert Hofman Jens-Christian Holm Momoko Horikoshi Jouke Jan Hottenga Jinyan Huang Haja N Kadarmideen Mika Kähönen Wieland Kiess Hanna-Maaria Lakka Timo A Lakka Alexandra M Lewin Liming Liang Leo-Pekka Lyytikäinen Baoshan Ma Per Magnus Shana E McCormack George McMahon Frank D Mentch Christel M Middeldorp Clare S Murray Katja Pahkala Tune H Pers Roland Pfäffle Dirkje S Postma Christine Power Angela Simpson Verena Sengpiel Carla M T Tiesler Maties Torrent André G Uitterlinden Joyce B van Meurs Rebecca Vinding Johannes Waage Jane Wardle Eleftheria Zeggini Babette S Zemel George V Dedoussis Oluf Pedersen Philippe Froguel Jordi Sunyer Robert Plomin Bo Jacobsson Torben Hansen Juan R Gonzalez Adnan Custovic Olli T Raitakari Craig E Pennell Elisabeth Widén Dorret I Boomsma Gerard H Koppelman Sylvain Sebert Marjo-Riitta Järvelin Elina Hyppönen Mark I McCarthy Virpi Lindi Niinikoski Harri Antje Körner Klaus Bønnelykke Joachim Heinrich Mads Melbye Fernando Rivadeneira Hakon Hakonarson Susan M Ring George Davey Smith Thorkild I A Sørensen Nicholas J Timpson Struan F A Grant Vincent W V Jaddoe

Hum Mol Genet 2016 Jan 24;25(2):389-403. Epub 2015 Nov 24.

The Generation R Study Group, Department of Pediatrics, Department of Epidemiology.

View Article

Download full-text PDF	Source
http://hmg.oxfordjournals.org/content/early/2015/12/16/hmg.d	Web Search
http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv	Publisher Site
http://dx.doi.org/10.1093/hmg/ddv472	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854022	PMC

January 2016

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

Authors:

Norihiro Kato Marie Loh Fumihiko Takeuchi Niek Verweij Xu Wang Weihua Zhang Tanika N Kelly Danish Saleheen Benjamin Lehne Irene Mateo Leach Alexander W Drong James Abbott Simone Wahl Sian-Tsung Tan William R Scott Gianluca Campanella Marc Chadeau-Hyam Uzma Afzal Tarunveer S Ahluwalia Marc Jan Bonder Peng Chen Abbas Dehghan Todd L Edwards Tõnu Esko Min Jin Go Sarah E Harris Jaana Hartiala Silva Kasela Anuradhani Kasturiratne Chiea-Chuen Khor Marcus E Kleber Huaixing Li Zuan Yu Mok Masahiro Nakatochi Nur Sabrina Sapari Richa Saxena Alexandre F R Stewart Lisette Stolk Yasuharu Tabara Ai Ling Teh Ying Wu Jer-Yuarn Wu Yi Zhang Imke Aits Alexessander Da Silva Couto Alves Shikta Das Rajkumar Dorajoo Jemma C Hopewell Yun Kyoung Kim Robert W Koivula Jian'an Luan Leo-Pekka Lyytikäinen Quang N Nguyen Mark A Pereira Iris Postmus Olli T Raitakari Molly Scannell Bryan Robert A Scott Rossella Sorice Vinicius Tragante Michela Traglia Jon White Ken Yamamoto Yonghong Zhang Linda S Adair Alauddin Ahmed Koichi Akiyama Rasheed Asif Tin Aung Inês Barroso Andrew Bjonnes Timothy R Braun Hui Cai Li-Ching Chang Chien-Hsiun Chen Ching-Yu Cheng Yap-Seng Chong Rory Collins Regina Courtney Gail Davies Graciela Delgado Loi D Do Pieter A Doevendans Ron T Gansevoort Yu-Tang Gao Tanja B Grammer Niels Grarup Jagvir Grewal Dongfeng Gu Gurpreet S Wander Anna-Liisa Hartikainen Stanley L Hazen Jing He Chew-Kiat Heng James E Hixson Albert Hofman Chris Hsu Wei Huang Lise L N Husemoen Joo-Yeon Hwang Sahoko Ichihara Michiya Igase Masato Isono Johanne M Justesen Tomohiro Katsuya Muhammad G Kibriya Young Jin Kim Miyako Kishimoto Woon-Puay Koh Katsuhiko Kohara Meena Kumari Kenneth Kwek Nanette R Lee Jeannette Lee Jiemin Liao Wolfgang Lieb David C M Liewald Tatsuaki Matsubara Yumi Matsushita Thomas Meitinger Evelin Mihailov Lili Milani Rebecca Mills Nina Mononen Martina Müller-Nurasyid Toru Nabika Eitaro Nakashima Hong Kiat Ng Kjell Nikus Teresa Nutile Takayoshi Ohkubo Keizo Ohnaka Sarah Parish Lavinia Paternoster Hao Peng Annette Peters Son T Pham Mohitha J Pinidiyapathirage Mahfuzar Rahman Hiromi Rakugi Olov Rolandsson Michelle Ann Rozario Daniela Ruggiero Cinzia F Sala Ralhan Sarju Kazuro Shimokawa Harold Snieder Thomas Sparsø Wilko Spiering John M Starr David J Stott Daniel O Stram Takao Sugiyama Silke Szymczak W H Wilson Tang Lin Tong Stella Trompet Väinö Turjanmaa Hirotsugu Ueshima André G Uitterlinden Satoshi Umemura Marja Vaarasmaki Rob M van Dam Wiek H van Gilst Dirk J van Veldhuisen Jorma S Viikari Melanie Waldenberger Yiqin Wang Aili Wang Rory Wilson Tien-Yin Wong Yong-Bing Xiang Shuhei Yamaguchi Xingwang Ye Robin D Young Terri L Young Jian-Min Yuan Xueya Zhou Folkert W Asselbergs Marina Ciullo Robert Clarke Panos Deloukas Andre Franke Paul W Franks Steve Franks Yechiel Friedlander Myron D Gross Zhirong Guo Torben Hansen Marjo-Riitta Jarvelin Torben Jørgensen J Wouter Jukema Mika Kähönen Hiroshi Kajio Mika Kivimaki Jong-Young Lee Terho Lehtimäki Allan Linneberg Tetsuro Miki Oluf Pedersen Nilesh J Samani Thorkild I A Sørensen Ryoichi Takayanagi Daniela Toniolo Habibul Ahsan Hooman Allayee Yuan-Tsong Chen John Danesh Ian J Deary Oscar H Franco Lude Franke Bastiaan T Heijman Joanna D Holbrook Aaron Isaacs Bong-Jo Kim Xu Lin Jianjun Liu Winfried März Andres Metspalu Karen L Mohlke Dharambir K Sanghera Xiao-Ou Shu Joyce B J van Meurs Eranga Vithana Ananda R Wickremasinghe Cisca Wijmenga Bruce H W Wolffenbuttel Mitsuhiro Yokota Wei Zheng Dingliang Zhu Paolo Vineis Soterios A Kyrtopoulos Jos C S Kleinjans Mark I McCarthy Richie Soong Christian Gieger James Scott Yik-Ying Teo Jiang He Paul Elliott E Shyong Tai Pim van der Harst Jaspal S Kooner John C Chambers

Nat Genet 2015 11 21;47(11):1282-1293. Epub 2015 Sep 21.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ng.3405	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719169	PMC

November 2015

The effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjects.

Authors:

Dieuwertje E G Kok Rosalie A M Dhonukshe-Rutten Carolien Lute Sandra G Heil André G Uitterlinden Nathalie van der Velde Joyce B J van Meurs Natasja M van Schoor Guido J E J Hooiveld Lisette C P G M de Groot Ellen Kampman Wilma T Steegenga

Clin Epigenetics 2015 14;7:121. Epub 2015 Nov 14.

Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/s13148-015-0154-5	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644301	PMC

November 2015

Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis.

Ann Rheum Dis 2015 Oct 13;74(10):1861-7. Epub 2014 Jun 13.

University of California at Davis, Sacramento, California, USA.

View Article

Download full-text PDF	Source
http://ard.bmj.com/content/74/10/1861.full.pdf	Web Search
http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2013-20502	Publisher Site
http://dx.doi.org/10.1136/annrheumdis-2013-205020	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449305	PMC

October 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:

Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/nature14878	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714	PMC

October 2015

The transcriptional landscape of age in human peripheral blood.

Authors:

Marjolein J Peters Roby Joehanes Luke C Pilling Claudia Schurmann Karen N Conneely Joseph Powell Eva Reinmaa George L Sutphin Alexandra Zhernakova Katharina Schramm Yana A Wilson Sayuko Kobes Taru Tukiainen Yolande F Ramos Harald H H Göring Myriam Fornage Yongmei Liu Sina A Gharib Barbara E Stranger Philip L De Jager Abraham Aviv Daniel Levy Joanne M Murabito Peter J Munson Tianxiao Huan Albert Hofman André G Uitterlinden Fernando Rivadeneira Jeroen van Rooij Lisette Stolk Linda Broer Michael M P J Verbiest Mila Jhamai Pascal Arp Andres Metspalu Liina Tserel Lili Milani Nilesh J Samani Pärt Peterson Silva Kasela Veryan Codd Annette Peters Cavin K Ward-Caviness Christian Herder Melanie Waldenberger Michael Roden Paula Singmann Sonja Zeilinger Thomas Illig Georg Homuth Hans-Jörgen Grabe Henry Völzke Leif Steil Thomas Kocher Anna Murray David Melzer Hanieh Yaghootkar Stefania Bandinelli Eric K Moses Jack W Kent Joanne E Curran Matthew P Johnson Sarah Williams-Blangero Harm-Jan Westra Allan F McRae Jennifer A Smith Sharon L R Kardia Iiris Hovatta Markus Perola Samuli Ripatti Veikko Salomaa Anjali K Henders Nicholas G Martin Alicia K Smith Divya Mehta Elisabeth B Binder K Maria Nylocks Elizabeth M Kennedy Torsten Klengel Jingzhong Ding Astrid M Suchy-Dicey Daniel A Enquobahrie Jennifer Brody Jerome I Rotter Yii-Der I Chen Jeanine Houwing-Duistermaat Margreet Kloppenburg P Eline Slagboom Quinta Helmer Wouter den Hollander Shannon Bean Towfique Raj Noman Bakhshi Qiao Ping Wang Lisa J Oyston Bruce M Psaty Russell P Tracy Grant W Montgomery Stephen T Turner John Blangero Ingrid Meulenbelt Kerry J Ressler Jian Yang Lude Franke Johannes Kettunen Peter M Visscher G Gregory Neely Ron Korstanje Robert L Hanson Holger Prokisch Luigi Ferrucci Tonu Esko Alexander Teumer Joyce B J van Meurs Andrew D Johnson

Nat Commun 2015 Oct 22;6:8570. Epub 2015 Oct 22.

The National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ncomms9570	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639797	PMC

October 2015

Markers of atherosclerosis in relation to presence and progression of knee osteoarthritis: a population-based cohort study.

Authors:

Theun A Hoeven Maryam Kavousi Muhammed A Ikram Joyce B van Meurs Patrick J Bindels Albert Hofman Oscar H Franco Sita M Bierma-Zeinstra

Rheumatology (Oxford) 2015 Sep 6;54(9):1692-8. Epub 2015 May 6.

Department of General Practice Department of Orthopaedics, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.

View Article

Download full-text PDF	Source
http://rheumatology.oxfordjournals.org/content/early/2015/05	Web Search
http://www.rheumatology.oxfordjournals.org/lookup/doi/10.109	Publisher Site
http://dx.doi.org/10.1093/rheumatology/kev106	DOI Listing

September 2015

Biomarkers for osteoarthritis: Can they be used for risk assessment? A systematic review.

Authors:

Fatemeh Saberi Hosnijeh Jos Runhaar Joyce B J van Meurs Sita M Bierma-Zeinstra

Maturitas 2015 Sep 14;82(1):36-49. Epub 2015 Apr 14.

Department of General Practice, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.maturitas.2015.04.004	DOI Listing

September 2015

Chronic joint pain in the lower body is associated with gait differences independent from radiographic osteoarthritis.

Authors:

Marjolein de Kruijf Vincentius J A Verlinden Frank J P M Huygen Albert Hofman Jos N van der Geest Andre G Uitterlinden Sita M A Bierma-Zeinstra M Arfan Ikram Joyce B J van Meurs

Gait Posture 2015 Sep 14;42(3):354-9. Epub 2015 Jul 14.

Department of Internal Medicine, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.gaitpost.2015.06.193	DOI Listing

September 2015

DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring.

Authors:

Leanne K Küpers Xiaojing Xu Soesma A Jankipersadsing Ahmad Vaez Sacha la Bastide-van Gemert Salome Scholtens Ilja M Nolte Rebecca C Richmond Caroline L Relton Janine F Felix Liesbeth Duijts Joyce B van Meurs Henning Tiemeier Vincent W Jaddoe Xiaoling Wang Eva Corpeleijn Harold Snieder

Int J Epidemiol 2015 Aug 10;44(4):1224-37. Epub 2015 Apr 10.

Departments of Epidemiology.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1093/ije/dyv048	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588868	PMC

August 2015

Cell Specific eQTL Analysis without Sorting Cells.

Authors:

Harm-Jan Westra Danny Arends Tõnu Esko Marjolein J Peters Claudia Schurmann Katharina Schramm Johannes Kettunen Hanieh Yaghootkar Benjamin P Fairfax Anand Kumar Andiappan Yang Li Jingyuan Fu Juha Karjalainen Mathieu Platteel Marijn Visschedijk Rinse K Weersma Silva Kasela Lili Milani Liina Tserel Pärt Peterson Eva Reinmaa Albert Hofman André G Uitterlinden Fernando Rivadeneira Georg Homuth Astrid Petersmann Roberto Lorbeer Holger Prokisch Thomas Meitinger Christian Herder Michael Roden Harald Grallert Samuli Ripatti Markus Perola Andrew R Wood David Melzer Luigi Ferrucci Andrew B Singleton Dena G Hernandez Julian C Knight Rossella Melchiotti Bernett Lee Michael Poidinger Francesca Zolezzi Anis Larbi De Yun Wang Leonard H van den Berg Jan H Veldink Olaf Rotzschke Seiko Makino Veikko Salomaa Konstantin Strauch Uwe Völker Joyce B J van Meurs Andres Metspalu Cisca Wijmenga Ritsert C Jansen Lude Franke

PLoS Genet 2015 May 8;11(5):e1005223. Epub 2015 May 8.

University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1371/journal.pgen.1005223	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425538	PMC

May 2015

Tobacco smoking is associated with methylation of genes related to coronary artery disease.

Authors:

Rebecca V Steenaard Symen Ligthart Lisette Stolk Marjolein J Peters Joyce B van Meurs Andre G Uitterlinden Albert Hofman Oscar H Franco Abbas Dehghan

Clin Epigenetics 2015 14;7:54. Epub 2015 May 14.

Department of Epidemiology, Erasmus University Medical Centre, 's Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/s13148-015-0088-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443552	PMC

May 2015

A meta-analysis of gene expression signatures of blood pressure and hypertension.

PLoS Genet 2015 Mar 18;11(3):e1005035. Epub 2015 Mar 18.

The National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, United States of America; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.

View Article

Download full-text PDF	Source
http://escholarship.org/uc/item/65v3g86k.pdf	Web Search
http://dx.plos.org/10.1371/journal.pgen.1005035	Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1005035	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365001	PMC

March 2015

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.

Authors:

Evangelos Evangelou Hanneke J Kerkhof Unnur Styrkarsdottir Evangelia E Ntzani Steffan D Bos Tonu Esko Daniel S Evans Sarah Metrustry Kalliope Panoutsopoulou Yolande F M Ramos Gudmar Thorleifsson Konstantinos K Tsilidis Nigel Arden Nadim Aslam Nicholas Bellamy Fraser Birrell Francisco J Blanco Andrew Carr Kay Chapman Aaron G Day-Williams Panos Deloukas Michael Doherty Gunnar Engström Hafdis T Helgadottir Albert Hofman Thorvaldur Ingvarsson Helgi Jonsson Aime Keis J Christiaan Keurentjes Margreet Kloppenburg Penelope A Lind Andrew McCaskie Nicholas G Martin Lili Milani Grant W Montgomery Rob G H H Nelissen Michael C Nevitt Peter M Nilsson William Er Ollier Neeta Parimi Ashok Rai Stuart H Ralston Mike R Reed Jose A Riancho Fernando Rivadeneira Cristina Rodriguez-Fontenla Lorraine Southam Unnur Thorsteinsdottir Aspasia Tsezou Gillian A Wallis J Mark Wilkinson Antonio Gonzalez Nancy E Lane L Stefan Lohmander John Loughlin Andres Metspalu Andre G Uitterlinden Ingileif Jonsdottir Kari Stefansson P Eline Slagboom Eleftheria Zeggini Ingrid Meulenbelt John Pa Ioannidis Tim D Spector Joyce B J van Meurs Ana M Valdes

Ann Rheum Dis 2014 Dec 29;73(12):2130-6. Epub 2013 Aug 29.

Department of Twin Research & Genetic Epidemiology, King's College London, London, UK Department of Academic Rheumatology, University of Nottingham, Nottingham, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1136/annrheumdis-2012-203114	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251181	PMC

December 2014

A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease.

Authors:

Mohsen Ghanbari Paul S de Vries Hans de Looper Marjolein J Peters Claudia Schurmann Hanieh Yaghootkar Marcus Dörr Timothy M Frayling Andre G Uitterlinden Albert Hofman Joyce B J van Meurs Stefan J Erkeland Oscar H Franco Abbas Dehghan

Hum Mutat 2014 Dec;35(12):1524-31

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

View Article

Download full-text PDF	Source
http://doi.wiley.com/10.1002/humu.22706	Publisher Site
http://dx.doi.org/10.1002/humu.22706	DOI Listing

December 2014

Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial.

Authors:

Janneke P van Wijngaarden Karin M A Swart Anke W Enneman Rosalie A M Dhonukshe-Rutten Suzanne C van Dijk Annelies C Ham Elske M Brouwer-Brolsma Nikita L van der Zwaluw Evelien Sohl Joyce B J van Meurs M Carola Zillikens Natasja M van Schoor Nathalie van der Velde Johannes Brug André G Uitterlinden Paul Lips Lisette C P G M de Groot

Am J Clin Nutr 2014 Dec 1;100(6):1578-86. Epub 2014 Oct 1.

From the Division of Human Nutrition, Wageningen University, Wageningen, Netherlands (JPvW, RAMD-R, EMB-B, NLvdZ, and LCPGMdG); the Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research (KMAS, ES, NMvS, JB, and PL) and the Department of Internal Medicine, Endocrine Section (PL), VU University Medical Center, Amsterdam, The Netherlands; the Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands (AWE, SCvD, ACH, JBJvM, MCZ, NvdV, and AGU); and the Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam, The Netherlands (NvdV).

View Article

Download full-text PDF	Source
https://academic.oup.com/ajcn/article/100/6/1578/4576655	Publisher Site
http://dx.doi.org/10.3945/ajcn.114.090043	DOI Listing

December 2014

Finger length pattern as a biomarker for osteoarthritis and chronic joint pain: a population-based study and meta-analysis after systematic review.

Authors:

Marjolein de Kruijf Hanneke J M Kerkhof Marjolein J Peters Sita Bierma-Zeinstra Albert Hofman Andre G Uitterlinden Frank J P M Huggen Joyce B J van Meurs

Arthritis Care Res (Hoboken) 2014 Sep;66(9):1337-43

Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1002/acr.22320	DOI Listing

September 2014

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.

J Med Genet 2014 Sep 23;51(9):596-604. Epub 2014 Jul 23.

Department of Molecular Epidemiology, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1136/jmedgenet-2014-102478	DOI Listing

September 2014

Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study.

Drugs Aging 2014 Aug;31(8):611-21

Department of Internal Medicine, Erasmus MC, Geriatric Section, University Medical Centre Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1007/s40266-014-0192-2	DOI Listing

August 2014

Effect of genetic variants associated with plasma homocysteine levels on stroke risk.

Stroke 2014 Jul 20;45(7):1920-4. Epub 2014 May 20.

From the Department of Medicine, Imperial College Cerebrovascular Research Unit, Imperial College London, London, United Kingdom (I.C., N.H., P.E.R., P.S.); Institute for Stroke and Dementia Research, Medical Centre, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany (R.M., M.D.); Center for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia (E.G.H.); Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom (K.R.A.); Department of Pathology, McMaster University, Hamilton, Ontario, Canada (G.P.); Departments of Epidemiology, Medicine, and Health Services, University of Washington, Seattle (B.M.P.); Group Health Research Institute, Group Health, Seattle, WA (B.M.P.); University of Texas Health Science Center at Houston (M.F.); Departments of Epidemiology, Neurology, and Radiology (M.A.I.) and Internal Medicine (J.B.J.v.M., A.G.U.), Erasmus MC University Medical Center, Rotterdam, The Netherlands; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom (H.S.M.); Department of Neurology (J.R.) and Center for Human Genetic Research (J.R.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (J.R.); Veterans Affairs Medical Center, Baltimore, MD (B.D.M., S.J.K.); Departments of Medicine (B.D.M., S.J.K.) and Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M.); Departments of Neurology (B.B.W.) and Public Health Science (B.B.W.), University of Virginia, Charlottesville; and Munich Cluster for Systems Neurology, Munich, Germany (M.D.).

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1161/STROKEAHA.114.005208	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083192	PMC

July 2014

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Authors:

Daan W Loth María Soler Artigas Sina A Gharib Louise V Wain Nora Franceschini Beate Koch Tess D Pottinger Albert Vernon Smith Qing Duan Chris Oldmeadow Mi Kyeong Lee David P Strachan Alan L James Jennifer E Huffman Veronique Vitart Adaikalavan Ramasamy Nicholas J Wareham Jaakko Kaprio Xin-Qun Wang Holly Trochet Mika Kähönen Claudia Flexeder Eva Albrecht Lorna M Lopez Kim de Jong Bharat Thyagarajan Alexessander Couto Alves Stefan Enroth Ernst Omenaas Peter K Joshi Tove Fall Ana Viñuela Lenore J Launer Laura R Loehr Myriam Fornage Guo Li Jemma B Wilk Wenbo Tang Ani Manichaikul Lies Lahousse Tamara B Harris Kari E North Alicja R Rudnicka Jennie Hui Xiangjun Gu Thomas Lumley Alan F Wright Nicholas D Hastie Susan Campbell Rajesh Kumar Isabelle Pin Robert A Scott Kirsi H Pietiläinen Ida Surakka Yongmei Liu Elizabeth G Holliday Holger Schulz Joachim Heinrich Gail Davies Judith M Vonk Mary Wojczynski Anneli Pouta Asa Johansson Sarah H Wild Erik Ingelsson Fernando Rivadeneira Henry Völzke Pirro G Hysi Gudny Eiriksdottir Alanna C Morrison Jerome I Rotter Wei Gao Dirkje S Postma Wendy B White Stephen S Rich Albert Hofman Thor Aspelund David Couper Lewis J Smith Bruce M Psaty Kurt Lohman Esteban G Burchard André G Uitterlinden Melissa Garcia Bonnie R Joubert Wendy L McArdle A Bill Musk Nadia Hansel Susan R Heckbert Lina Zgaga Joyce B J van Meurs Pau Navarro Igor Rudan Yeon-Mok Oh Susan Redline Deborah L Jarvis Jing Hua Zhao Taina Rantanen George T O'Connor Samuli Ripatti Rodney J Scott Stefan Karrasch Harald Grallert Nathan C Gaddis John M Starr Cisca Wijmenga Ryan L Minster David J Lederer Juha Pekkanen Ulf Gyllensten Harry Campbell Andrew P Morris Sven Gläser Christopher J Hammond Kristin M Burkart John Beilby Stephen B Kritchevsky Vilmundur Gudnason Dana B Hancock O Dale Williams Ozren Polasek Tatijana Zemunik Ivana Kolcic Marcy F Petrini Matthias Wjst Woo Jin Kim David J Porteous Generation Scotland Blair H Smith Anne Viljanen Markku Heliövaara John R Attia Ian Sayers Regina Hampel Christian Gieger Ian J Deary H Marike Boezen Anne Newman Marjo-Riitta Jarvelin James F Wilson Lars Lind Bruno H Stricker Alexander Teumer Timothy D Spector Erik Melén Marjolein J Peters Leslie A Lange R Graham Barr Ken R Bracke Fien M Verhamme Joohon Sung Pieter S Hiemstra Patricia A Cassano Akshay Sood Caroline Hayward Josée Dupuis Ian P Hall Guy G Brusselle Martin D Tobin Stephanie J London

Nat Genet 2014 Jul 15;46(7):669-77. Epub 2014 Jun 15.

1] Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, North Carolina, USA. [2].

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ng.3011	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140093	PMC

July 2014

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies.

Authors:

Cristina Rodriguez-Fontenla Manuel Calaza Evangelos Evangelou Ana M Valdes Nigel Arden Francisco J Blanco Andrew Carr Kay Chapman Panos Deloukas Michael Doherty Tõnu Esko Carlos M Garcés Aletá Juan J Gomez-Reino Carnota Hafdis Helgadottir Albert Hofman Ingileif Jonsdottir Hanneke J M Kerkhof Margreet Kloppenburg Andrew McCaskie Evangelia E Ntzani William E R Ollier Natividad Oreiro Kalliope Panoutsopoulou Stuart H Ralston Yolande F Ramos Jose A Riancho Fernando Rivadeneira P Eline Slagboom Unnur Styrkarsdottir Unnur Thorsteinsdottir Gudmar Thorleifsson Aspasia Tsezou André G Uitterlinden Gillian A Wallis J Mark Wilkinson Guangju Zhai Yanyan Zhu David T Felson John P A Ioannidis John Loughlin Andres Metspalu Ingrid Meulenbelt Kari Stefansson Joyce B van Meurs Eleftheria Zeggini Timothy D Spector Antonio Gonzalez

Arthritis Rheumatol 2014 Apr;66(4):940-9

Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1002/art.38300	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660891	PMC

April 2014

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

Authors:

Ling Oei Yi-Hsiang Hsu Unnur Styrkarsdottir Bert H Eussen Annelies de Klein Marjolein J Peters Bjarni Halldorsson Ching-Ti Liu Nerea Alonso Stephen K Kaptoge Gudmar Thorleifsson Göran Hallmans Lynne J Hocking Lise Bjerre Husted Karen A Jameson Marcin Kruk Joshua R Lewis Millan S Patel Serena Scollen Olle Svensson Stella Trompet Natasja M van Schoor Kun Zhu Brendan M Buckley Cyrus Cooper Ian Ford David Goltzman Jesús González-Macías Bente Lomholt Langdahl William D Leslie Paul Lips Roman S Lorenc José M Olmos Ulrika Pettersson-Kymmer David M Reid José A Riancho P Eline Slagboom Carmen Garcia-Ibarbia Thorvaldur Ingvarsson Hrefna Johannsdottir Robert Luben Carolina Medina-Gómez Pascal Arp Kannabiran Nandakumar Stefan Th Palsson Gunnar Sigurdsson Joyce B J van Meurs Yanhua Zhou Albert Hofman J Wouter Jukema Huibert A P Pols Richard L Prince L Adrienne Cupples Christian R Marshall Dalila Pinto Daisuke Sato Stephen W Scherer Jonathan Reeve Unnur Thorsteinsdottir David Karasik J Brent Richards Kari Stefansson André G Uitterlinden Stuart H Ralston John P A Ioannidis Douglas P Kiel Fernando Rivadeneira Karol Estrada

J Med Genet 2014 Feb 16;51(2):122-31. Epub 2013 Dec 16.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://www.molepi.nl/uploads/publicaties/2014/2014_oei_jmedg	Web Search
http://jmg.bmj.com/cgi/doi/10.1136/jmedgenet-2013-102064	Publisher Site
http://dx.doi.org/10.1136/jmedgenet-2013-102064	DOI Listing

February 2014

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus.

Authors:

Ling Oei Karol Estrada Emma L Duncan Claus Christiansen Ching-Ti Liu Bente L Langdahl Barbara Obermayer-Pietsch José A Riancho Richard L Prince Natasja M van Schoor Eugene McCloskey Yi-Hsiang Hsu Evangelos Evangelou Evangelia Ntzani David M Evans Nerea Alonso Lise B Husted Carmen Valero Jose L Hernandez Joshua R Lewis Stephen K Kaptoge Kun Zhu L Adrienne Cupples Carolina Medina-Gómez Liesbeth Vandenput Ghi Su Kim Seung Hun Lee Martha C Castaño-Betancourt Edwin H G Oei Josefina Martinez Anna Daroszewska Marjolein van der Klift Dan Mellström Lizbeth Herrera Magnus K Karlsson Albert Hofman Östen Ljunggren Huibert A P Pols Lisette Stolk Joyce B J van Meurs John P A Ioannidis M Carola Zillikens Paul Lips David Karasik André G Uitterlinden Unnur Styrkarsdottir Matthew A Brown Jung-Min Koh J Brent Richards Jonathan Reeve Claes Ohlsson Stuart H Ralston Douglas P Kiel Fernando Rivadeneira

Bone 2014 Feb;59:20-7

View Article

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102322	PMC

February 2014

Systematic identification of trans eQTLs as putative drivers of known disease associations.

Authors:

Harm-Jan Westra Marjolein J Peters Tõnu Esko Hanieh Yaghootkar Claudia Schurmann Johannes Kettunen Mark W Christiansen Benjamin P Fairfax Katharina Schramm Joseph E Powell Alexandra Zhernakova Daria V Zhernakova Jan H Veldink Leonard H Van den Berg Juha Karjalainen Sebo Withoff André G Uitterlinden Albert Hofman Fernando Rivadeneira Peter A C 't Hoen Eva Reinmaa Krista Fischer Mari Nelis Lili Milani David Melzer Luigi Ferrucci Andrew B Singleton Dena G Hernandez Michael A Nalls Georg Homuth Matthias Nauck Dörte Radke Uwe Völker Markus Perola Veikko Salomaa Jennifer Brody Astrid Suchy-Dicey Sina A Gharib Daniel A Enquobahrie Thomas Lumley Grant W Montgomery Seiko Makino Holger Prokisch Christian Herder Michael Roden Harald Grallert Thomas Meitinger Konstantin Strauch Yang Li Ritsert C Jansen Peter M Visscher Julian C Knight Bruce M Psaty Samuli Ripatti Alexander Teumer Timothy M Frayling Andres Metspalu Joyce B J van Meurs Lude Franke

Nat Genet 2013 Oct 8;45(10):1238-1243. Epub 2013 Sep 8.

Department of Genetics, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ng.2756	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991562	PMC

October 2013

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

Authors:

Joyce B J van Meurs Guillaume Pare Stephen M Schwartz Aditi Hazra Toshiko Tanaka Sita H Vermeulen Ioana Cotlarciuc Xin Yuan Anders Mälarstig Stefania Bandinelli Joshua C Bis Henk Blom Morris J Brown Constance Chen Yii-Der Chen Robert J Clarke Abbas Dehghan Jeanette Erdmann Luigi Ferrucci Anders Hamsten Albert Hofman David J Hunter Anuj Goel Andrew D Johnson Sekar Kathiresan Ellen Kampman Douglas P Kiel Lambertus A L M Kiemeney John C Chambers Peter Kraft Jan Lindemans Barbara McKnight Christopher P Nelson Christopher J O'Donnell Bruce M Psaty Paul M Ridker Fernando Rivadeneira Lynda M Rose Udo Seedorf David S Siscovick Heribert Schunkert Jacob Selhub Per M Ueland Peter Vollenweider Gérard Waeber Dawn M Waterworth Hugh Watkins Jacqueline C M Witteman Martin den Heijer Paul Jacques Andre G Uitterlinden Jaspal S Kooner Dan J Rader Muredach P Reilly Vincent Mooser Daniel I Chasman Nilesh J Samani Kourosh R Ahmadi

Am J Clin Nutr 2013 Sep 3;98(3):668-76. Epub 2013 Jul 3.

Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.3945/ajcn.112.044545	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321227	PMC

September 2013

Scheuermann disease: evaluation of radiological criteria and population prevalence.

Authors:

Ater A Makurthou Ling Oei Salih El Saddy Stephan J Breda Martha C Castaño-Betancourt Albert Hofman Joyce B J van Meurs André G Uitterlinden Fernando Rivadeneira Edwin H G Oei

Spine (Phila Pa 1976) 2013 Sep;38(19):1690-4

From the Departments of *Internal Medicine †Radiology, and ‡Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; and §Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging, The Hague, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1097/BRS.0b013e31829ee8b7	DOI Listing

September 2013

Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects.

Authors:

Frances M K Williams Aruna T Bansal Joyce B van Meurs Jordana T Bell Ingrid Meulenbelt Pradeep Suri Fernando Rivadeneira Philip N Sambrook Albert Hofman Sita Bierma-Zeinstra Cristina Menni Margreet Kloppenburg P Eline Slagboom David J Hunter Alex J MacGregor Andre G Uitterlinden Tim D Spector

Ann Rheum Dis 2013 Jul 19;72(7):1141-8. Epub 2012 Sep 19.

Department Twin Research and Genetic Epidemiology, King's College London, London, UK.

View Article

Download full-text PDF	Source
http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2012-20155	Publisher Site
http://dx.doi.org/10.1136/annrheumdis-2012-201551	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686263	PMC

July 2013

The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males.

Ann Rheum Dis 2013 Jul 16;72(7):1264-5. Epub 2013 Mar 16.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1136/annrheumdis-2012-203182	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686326	PMC

July 2013

High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study.

Authors:

Ling Oei M Carola Zillikens Abbas Dehghan Gabriëlle H S Buitendijk Martha C Castaño-Betancourt Karol Estrada Lisette Stolk Edwin H G Oei Joyce B J van Meurs Joseph A M J L Janssen Albert Hofman Johannes P T M van Leeuwen Jacqueline C M Witteman Huibert A P Pols André G Uitterlinden Caroline C W Klaver Oscar H Franco Fernando Rivadeneira

Diabetes Care 2013 Jun 11;36(6):1619-28. Epub 2013 Jan 11.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.2337/dc12-1188	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661786	PMC

June 2013

Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study.

Authors:

Theun Antonius Hoeven Maryam Kavousi Stefan Clockaerts Hanneke J M Kerkhof Joyce B van Meurs Oscar Franco Albert Hofman Patrick Bindels Jacqueline Witteman Sita Bierma-Zeinstra

Ann Rheum Dis 2013 May 6;72(5):646-51. Epub 2012 May 6.

Erasmus University Medical Centre, General Practice, Rotterdam 3015 CA, The Netherlands.

View Article

Download full-text PDF	Source
http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2011-20117	Publisher Site
http://dx.doi.org/10.1136/annrheumdis-2011-201178	DOI Listing

May 2013

Factors for pain in patients with different grades of knee osteoarthritis.

Authors:

Dieuwke Schiphof Hanneke J M Kerkhof Jurgen Damen Bianca M de Klerk Albert Hofman Bart W Koes Joyce B J van Meurs Sita M A Bierma-Zeinstra

Arthritis Care Res (Hoboken) 2013 May;65(5):695-702

Department of General Practice, Erasmus MC, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1002/acr.21886	DOI Listing

May 2013

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

Authors:

Sonja I Berndt Stefan Gustafsson Reedik Mägi Andrea Ganna Eleanor Wheeler Mary F Feitosa Anne E Justice Keri L Monda Damien C Croteau-Chonka Felix R Day Tõnu Esko Tove Fall Teresa Ferreira Davide Gentilini Anne U Jackson Jian'an Luan Joshua C Randall Sailaja Vedantam Cristen J Willer Thomas W Winkler Andrew R Wood Tsegaselassie Workalemahu Yi-Juan Hu Sang Hong Lee Liming Liang Dan-Yu Lin Josine L Min Benjamin M Neale Gudmar Thorleifsson Jian Yang Eva Albrecht Najaf Amin Jennifer L Bragg-Gresham Gemma Cadby Martin den Heijer Niina Eklund Krista Fischer Anuj Goel Jouke-Jan Hottenga Jennifer E Huffman Ivonne Jarick Åsa Johansson Toby Johnson Stavroula Kanoni Marcus E Kleber Inke R König Kati Kristiansson Zoltán Kutalik Claudia Lamina Cecile Lecoeur Guo Li Massimo Mangino Wendy L McArdle Carolina Medina-Gomez Martina Müller-Nurasyid Julius S Ngwa Ilja M Nolte Lavinia Paternoster Sonali Pechlivanis Markus Perola Marjolein J Peters Michael Preuss Lynda M Rose Jianxin Shi Dmitry Shungin Albert Vernon Smith Rona J Strawbridge Ida Surakka Alexander Teumer Mieke D Trip Jonathan Tyrer Jana V Van Vliet-Ostaptchouk Liesbeth Vandenput Lindsay L Waite Jing Hua Zhao Devin Absher Folkert W Asselbergs Mustafa Atalay Antony P Attwood Anthony J Balmforth Hanneke Basart John Beilby Lori L Bonnycastle Paolo Brambilla Marcel Bruinenberg Harry Campbell Daniel I Chasman Peter S Chines Francis S Collins John M Connell William O Cookson Ulf de Faire Femmie de Vegt Mariano Dei Maria Dimitriou Sarah Edkins Karol Estrada David M Evans Martin Farrall Marco M Ferrario Jean Ferrières Lude Franke Francesca Frau Pablo V Gejman Harald Grallert Henrik Grönberg Vilmundur Gudnason Alistair S Hall Per Hall Anna-Liisa Hartikainen Caroline Hayward Nancy L Heard-Costa Andrew C Heath Johannes Hebebrand Georg Homuth Frank B Hu Sarah E Hunt Elina Hyppönen Carlos Iribarren Kevin B Jacobs John-Olov Jansson Antti Jula Mika Kähönen Sekar Kathiresan Frank Kee Kay-Tee Khaw Mika Kivimäki Wolfgang Koenig Aldi T Kraja Meena Kumari Kari Kuulasmaa Johanna Kuusisto Jaana H Laitinen Timo A Lakka Claudia Langenberg Lenore J Launer Lars Lind Jaana Lindström Jianjun Liu Antonio Liuzzi Marja-Liisa Lokki Mattias Lorentzon Pamela A Madden Patrik K Magnusson Paolo Manunta Diana Marek Winfried März Irene Mateo Leach Barbara McKnight Sarah E Medland Evelin Mihailov Lili Milani Grant W Montgomery Vincent Mooser Thomas W Mühleisen Patricia B Munroe Arthur W Musk Narisu Narisu Gerjan Navis George Nicholson Ellen A Nohr Ken K Ong Ben A Oostra Colin N A Palmer Aarno Palotie John F Peden Nancy Pedersen Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Inga Prokopenko Carolin Pütter Aparna Radhakrishnan Olli Raitakari Augusto Rendon Fernando Rivadeneira Igor Rudan Timo E Saaristo Jennifer G Sambrook Alan R Sanders Serena Sanna Jouko Saramies Sabine Schipf Stefan Schreiber Heribert Schunkert So-Youn Shin Stefano Signorini Juha Sinisalo Boris Skrobek Nicole Soranzo Alena Stančáková Klaus Stark Jonathan C Stephens Kathleen Stirrups Ronald P Stolk Michael Stumvoll Amy J Swift Eirini V Theodoraki Barbara Thorand David-Alexandre Tregouet Elena Tremoli Melanie M Van der Klauw Joyce B J van Meurs Sita H Vermeulen Jorma Viikari Jarmo Virtamo Veronique Vitart Gérard Waeber Zhaoming Wang Elisabeth Widén Sarah H Wild Gonneke Willemsen Bernhard R Winkelmann Jacqueline C M Witteman Bruce H R Wolffenbuttel Andrew Wong Alan F Wright M Carola Zillikens Philippe Amouyel Bernhard O Boehm Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock L Adrienne Cupples Daniele Cusi George V Dedoussis Jeanette Erdmann Johan G Eriksson Paul W Franks Philippe Froguel Christian Gieger Ulf Gyllensten Anders Hamsten Tamara B Harris Christian Hengstenberg Andrew A Hicks Aroon Hingorani Anke Hinney Albert Hofman Kees G Hovingh Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Karl-Heinz Jöckel Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Diana Kuh Markku Laakso Terho Lehtimäki Douglas F Levinson Nicholas G Martin Andres Metspalu Andrew D Morris Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Willem H Ouwehand Lyle J Palmer Brenda Penninx Chris Power Michael A Province Bruce M Psaty Lu Qi Rainer Rauramaa Paul M Ridker Samuli Ripatti Veikko Salomaa Nilesh J Samani Harold Snieder Thorkild I A Sørensen Timothy D Spector Kari Stefansson Anke Tönjes Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Peter Vollenweider Henri Wallaschofski Nicholas J Wareham Hugh Watkins H-Erich Wichmann James F Wilson Goncalo R Abecasis Themistocles L Assimes Inês Barroso Michael Boehnke Ingrid B Borecki Panos Deloukas Caroline S Fox Timothy Frayling Leif C Groop Talin Haritunian Iris M Heid David Hunter Robert C Kaplan Fredrik Karpe Miriam F Moffatt Karen L Mohlke Jeffrey R O'Connell Yudi Pawitan Eric E Schadt David Schlessinger Valgerdur Steinthorsdottir David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Peter M Visscher Anna Maria Di Blasio Joel N Hirschhorn Cecilia M Lindgren Andrew P Morris David Meyre André Scherag Mark I McCarthy Elizabeth K Speliotes Kari E North Ruth J F Loos Erik Ingelsson

Nat Genet 2013 May 7;45(5):501-12. Epub 2013 Apr 7.

US Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ng.2606	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973018	PMC

May 2013

Identification of genetic loci associated with Helicobacter pylori serologic status.

JAMA 2013 May;309(18):1912-20

Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1001/jama.2013.4350	DOI Listing

May 2013

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region.

Authors:

Marjolein J Peters Linda Broer Hanneke L D M Willemen Gudny Eiriksdottir Lynne J Hocking Kate L Holliday Michael A Horan Ingrid Meulenbelt Tuhina Neogi Maria Popham Carsten O Schmidt Anushka Soni Ana M Valdes Najaf Amin Elaine M Dennison Niels Eijkelkamp Tamara B Harris Deborah J Hart Albert Hofman Frank J P M Huygen Karen A Jameson Gareth T Jones Lenore J Launer Hanneke J M Kerkhof Marjolein de Kruijf John McBeth Margreet Kloppenburg William E Ollier Ben Oostra Antony Payton Fernando Rivadeneira Blair H Smith Albert V Smith Lisette Stolk Alexander Teumer Wendy Thomson André G Uitterlinden Ke Wang Sophie H van Wingerden Nigel K Arden Cyrus Cooper David Felson Vilmundur Gudnason Gary J Macfarlane Neil Pendleton P Eline Slagboom Tim D Spector Henry Völzke Annemieke Kavelaars Cornelia M van Duijn Frances M K Williams Joyce B J van Meurs

Ann Rheum Dis 2013 Mar 6;72(3):427-36. Epub 2012 Sep 6.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1136/annrheumdis-2012-201742	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691951	PMC

March 2013

Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk.

Authors:

Martha C Castaño-Betancourt Fernando Rivadeneira Sita Bierma-Zeinstra Hanneke J M Kerkhof Albert Hofman Andre G Uitterlinden Joyce B J van Meurs

Arthritis Rheum 2013 Mar;65(3):693-700

Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1002/art.37792	DOI Listing

March 2013

Genome-wide meta-analysis of common variant differences between men and women.

Authors:

Vesna Boraska Ana Jerončić Vincenza Colonna Lorraine Southam Dale R Nyholt Nigel William Rayner John R B Perry Daniela Toniolo Eva Albrecht Wei Ang Stefania Bandinelli Maja Barbalic Inês Barroso Jacques S Beckmann Reiner Biffar Dorret Boomsma Harry Campbell Tanguy Corre Jeanette Erdmann Tõnu Esko Krista Fischer Nora Franceschini Timothy M Frayling Giorgia Girotto Juan R Gonzalez Tamara B Harris Andrew C Heath Iris M Heid Wolfgang Hoffmann Albert Hofman Momoko Horikoshi Jing Hua Zhao Anne U Jackson Jouke-Jan Hottenga Antti Jula Mika Kähönen Kay-Tee Khaw Lambertus A Kiemeney Norman Klopp Zoltán Kutalik Vasiliki Lagou Lenore J Launer Terho Lehtimäki Mathieu Lemire Marja-Liisa Lokki Christina Loley Jian'an Luan Massimo Mangino Irene Mateo Leach Sarah E Medland Evelin Mihailov Grant W Montgomery Gerjan Navis John Newnham Markku S Nieminen Aarno Palotie Kalliope Panoutsopoulou Annette Peters Nicola Pirastu Ozren Polasek Karola Rehnström Samuli Ripatti Graham R S Ritchie Fernando Rivadeneira Antonietta Robino Nilesh J Samani So-Youn Shin Juha Sinisalo Johannes H Smit Nicole Soranzo Lisette Stolk Dorine W Swinkels Toshiko Tanaka Alexander Teumer Anke Tönjes Michela Traglia Jaakko Tuomilehto Armand Valsesia Wiek H van Gilst Joyce B J van Meurs Albert Vernon Smith Jorma Viikari Jacqueline M Vink Gerard Waeber Nicole M Warrington Elisabeth Widen Gonneke Willemsen Alan F Wright Brent W Zanke Lina Zgaga Michael Boehnke Adamo Pio d'Adamo Eco de Geus Ellen W Demerath Martin den Heijer Johan G Eriksson Luigi Ferrucci Christian Gieger Vilmundur Gudnason Caroline Hayward Christian Hengstenberg Thomas J Hudson Marjo-Riitta Järvelin Manolis Kogevinas Ruth J F Loos Nicholas G Martin Andres Metspalu Craig E Pennell Brenda W Penninx Markus Perola Olli Raitakari Veikko Salomaa Stefan Schreiber Heribert Schunkert Tim D Spector Michael Stumvoll André G Uitterlinden Sheila Ulivi Pim van der Harst Peter Vollenweider Henry Völzke Nicholas J Wareham H-Erich Wichmann James F Wilson Igor Rudan Yali Xue Eleftheria Zeggini

Hum Mol Genet 2012 Nov 27;21(21):4805-15. Epub 2012 Jul 27.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1093/hmg/dds304	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471397	PMC

November 2012

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

Authors:

Eleftheria Zeggini Kalliope Panoutsopoulou Lorraine Southam Nigel W Rayner Aaron G Day-Williams Margarida C Lopes Vesna Boraska Tonu Esko Evangelos Evangelou Albert Hoffman Jeanine J Houwing-Duistermaat Thorvaldur Ingvarsson Ingileif Jonsdottir Helgi Jonnson Hanneke J Kerkhof Margreet Kloppenburg Steffan D Bos Massimo Mangino Sarah Metrustry P Eline Slagboom Gudmar Thorleifsson Emma V A Raine Madhushika Ratnayake Michelle Ricketts Claude Beazley Hannah Blackburn Suzannah Bumpstead Katherine S Elliott Sarah E Hunt Simon C Potter So-Youn Shin Vijay K Yadav Guangju Zhai Kate Sherburn Kate Dixon Elizabeth Arden Nadim Aslam Phillippa-kate Battley Ian Carluke Sally Doherty Andrew Gordon John Joseph Richard Keen Nicola C Koller Sheryl Mitchell Fiona O'Neill Ellen Paling Mike R Reed Fernando Rivadeneira Diane Swift Kirsten Walker Bridget Watkins Maggie Wheeler Fraser Birrell John P A Ioannidis Ingrid Meulenbelt Andres Metspalu Ashok Rai Donald Salter Kari Stefansson Unnur Stykarsdottir André G Uitterlinden Joyce B J van Meurs Kay Chapman Panos Deloukas William E R Ollier Gillian A Wallis Nigel Arden Andrew Carr Michael Doherty Andrew McCaskie J Mark Willkinson Stuart H Ralston Ana M Valdes Tim D Spector John Loughlin

Lancet 2012 Sep 3;380(9844):815-23. Epub 2012 Jul 3.

Wellcome Trust Sanger Institute, Morgan Building, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

View Article

Download full-text PDF	Source
http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(	Web Search
http://linkinghub.elsevier.com/retrieve/pii/S014067361260681	Publisher Site
http://dx.doi.org/10.1016/S0140-6736(12)60681-3	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443899	PMC

September 2012

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.

Proc Natl Acad Sci U S A 2012 May 7;109(21):8218-23. Epub 2012 May 7.

Department of Internal Medicine, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://ard.bmj.com/content/74/10/1861.full.pdf	Web Search
http://www.pnas.org/cgi/doi/10.1073/pnas.1119899109	Publisher Site
http://dx.doi.org/10.1073/pnas.1119899109	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361426	PMC

May 2012

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Authors:

Karol Estrada Unnur Styrkarsdottir Evangelos Evangelou Yi-Hsiang Hsu Emma L Duncan Evangelia E Ntzani Ling Oei Omar M E Albagha Najaf Amin John P Kemp Daniel L Koller Guo Li Ching-Ti Liu Ryan L Minster Alireza Moayyeri Liesbeth Vandenput Dana Willner Su-Mei Xiao Laura M Yerges-Armstrong Hou-Feng Zheng Nerea Alonso Joel Eriksson Candace M Kammerer Stephen K Kaptoge Paul J Leo Gudmar Thorleifsson Scott G Wilson James F Wilson Ville Aalto Markku Alen Aaron K Aragaki Thor Aspelund Jacqueline R Center Zoe Dailiana David J Duggan Melissa Garcia Natàlia Garcia-Giralt Sylvie Giroux Göran Hallmans Lynne J Hocking Lise Bjerre Husted Karen A Jameson Rita Khusainova Ghi Su Kim Charles Kooperberg Theodora Koromila Marcin Kruk Marika Laaksonen Andrea Z Lacroix Seung Hun Lee Ping C Leung Joshua R Lewis Laura Masi Simona Mencej-Bedrac Tuan V Nguyen Xavier Nogues Millan S Patel Janez Prezelj Lynda M Rose Serena Scollen Kristin Siggeirsdottir Albert V Smith Olle Svensson Stella Trompet Olivia Trummer Natasja M van Schoor Jean Woo Kun Zhu Susana Balcells Maria Luisa Brandi Brendan M Buckley Sulin Cheng Claus Christiansen Cyrus Cooper George Dedoussis Ian Ford Morten Frost David Goltzman Jesús González-Macías Mika Kähönen Magnus Karlsson Elza Khusnutdinova Jung-Min Koh Panagoula Kollia Bente Lomholt Langdahl William D Leslie Paul Lips Östen Ljunggren Roman S Lorenc Janja Marc Dan Mellström Barbara Obermayer-Pietsch José M Olmos Ulrika Pettersson-Kymmer David M Reid José A Riancho Paul M Ridker François Rousseau P Eline Slagboom Nelson L S Tang Roser Urreizti Wim Van Hul Jorma Viikari María T Zarrabeitia Yurii S Aulchenko Martha Castano-Betancourt Elin Grundberg Lizbeth Herrera Thorvaldur Ingvarsson Hrefna Johannsdottir Tony Kwan Rui Li Robert Luben Carolina Medina-Gómez Stefan Th Palsson Sjur Reppe Jerome I Rotter Gunnar Sigurdsson Joyce B J van Meurs Dominique Verlaan Frances M K Williams Andrew R Wood Yanhua Zhou Kaare M Gautvik Tomi Pastinen Soumya Raychaudhuri Jane A Cauley Daniel I Chasman Graeme R Clark Steven R Cummings Patrick Danoy Elaine M Dennison Richard Eastell John A Eisman Vilmundur Gudnason Albert Hofman Rebecca D Jackson Graeme Jones J Wouter Jukema Kay-Tee Khaw Terho Lehtimäki Yongmei Liu Mattias Lorentzon Eugene McCloskey Braxton D Mitchell Kannabiran Nandakumar Geoffrey C Nicholson Ben A Oostra Munro Peacock Huibert A P Pols Richard L Prince Olli Raitakari Ian R Reid John Robbins Philip N Sambrook Pak Chung Sham Alan R Shuldiner Frances A Tylavsky Cornelia M van Duijn Nick J Wareham L Adrienne Cupples Michael J Econs David M Evans Tamara B Harris Annie Wai Chee Kung Bruce M Psaty Jonathan Reeve Timothy D Spector Elizabeth A Streeten M Carola Zillikens Unnur Thorsteinsdottir Claes Ohlsson David Karasik J Brent Richards Matthew A Brown Kari Stefansson André G Uitterlinden Stuart H Ralston John P A Ioannidis Douglas P Kiel Fernando Rivadeneira

Nat Genet 2012 Apr 15;44(5):491-501. Epub 2012 Apr 15.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://kooperberg.fhcrc.org/papers/2012estrada.pdf	Web Search
http://www.nature.com/doifinder/10.1038/ng.2249	Publisher Site
http://dx.doi.org/10.1038/ng.2249	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338864	PMC

April 2012

A large-scale population-based analysis of common genetic variation in the thyroid hormone receptor alpha locus and bone.

Authors:

Marco Medici Fernando Rivadeneira Wendy M van der Deure Albert Hofman Joyce B J van Meurs Unnur Styrkársdottir Cornelia M van Duijn Timothy Spector Douglas P Kiel André G Uitterlinden Theo J Visser Robin P Peeters

Thyroid 2012 Feb 6;22(2):223-4. Epub 2012 Jan 6.

View Article

Download full-text PDF	Source
https://www.liebertpub.com/doi/10.1089/thy.2011.0245	Publisher Site
http://dx.doi.org/10.1089/thy.2011.0245	DOI Listing

February 2012

Rationale and design of the B-PROOF study, a randomized controlled trial on the effect of supplemental intake of vitamin B12 and folic acid on fracture incidence.

Authors:

Janneke P van Wijngaarden Rosalie A M Dhonukshe-Rutten Natasja M van Schoor Nathalie van der Velde Karin M A Swart Anke W Enneman Suzanne C van Dijk Elske M Brouwer-Brolsma M Carola Zillikens Joyce B J van Meurs Johannes Brug André G Uitterlinden Paul Lips Lisette C P G M de Groot

BMC Geriatr 2011 Dec 2;11:80. Epub 2011 Dec 2.

Department of Human Nutrition, Wageningen University, P,O, Box 8129 6700 EV Wageningen, the Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/1471-2318-11-80	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266639	PMC

December 2011

A variant in MCF2L is associated with osteoarthritis.

Am J Hum Genet 2011 Sep 25;89(3):446-50. Epub 2011 Aug 25.

Wellcome Trust Sanger Institute, Hinxton, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.ajhg.2011.08.001	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169824	PMC

September 2011

Mild hyponatremia as a risk factor for fractures: the Rotterdam Study.

Authors:

Ewout J Hoorn Fernando Rivadeneira Joyce B J van Meurs Gijsbertus Ziere Bruno H Ch Stricker Albert Hofman Huibert A P Pols Robert Zietse André G Uitterlinden M Carola Zillikens

J Bone Miner Res 2011 Aug;26(8):1822-8

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1002/jbmr.380	DOI Listing

August 2011

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

Authors:

Cathy E Elks John R B Perry Patrick Sulem Daniel I Chasman Nora Franceschini Chunyan He Kathryn L Lunetta Jenny A Visser Enda M Byrne Diana L Cousminer Daniel F Gudbjartsson Tõnu Esko Bjarke Feenstra Jouke-Jan Hottenga Daniel L Koller Zoltán Kutalik Peng Lin Massimo Mangino Mara Marongiu Patrick F McArdle Albert V Smith Lisette Stolk Sophie H van Wingerden Jing Hua Zhao Eva Albrecht Tanguy Corre Erik Ingelsson Caroline Hayward Patrik K E Magnusson Erin N Smith Shelia Ulivi Nicole M Warrington Lina Zgaga Helen Alavere Najaf Amin Thor Aspelund Stefania Bandinelli Inês Barroso Gerald S Berenson Sven Bergmann Hannah Blackburn Eric Boerwinkle Julie E Buring Fabio Busonero Harry Campbell Stephen J Chanock Wei Chen Marilyn C Cornelis David Couper Andrea D Coviello Pio d'Adamo Ulf de Faire Eco J C de Geus Panos Deloukas Angela Döring George Davey Smith Douglas F Easton Gudny Eiriksdottir Valur Emilsson Johan Eriksson Luigi Ferrucci Aaron R Folsom Tatiana Foroud Melissa Garcia Paolo Gasparini Frank Geller Christian Gieger Vilmundur Gudnason Per Hall Susan E Hankinson Liana Ferreli Andrew C Heath Dena G Hernandez Albert Hofman Frank B Hu Thomas Illig Marjo-Riitta Järvelin Andrew D Johnson David Karasik Kay-Tee Khaw Douglas P Kiel Tuomas O Kilpeläinen Ivana Kolcic Peter Kraft Lenore J Launer Joop S E Laven Shengxu Li Jianjun Liu Daniel Levy Nicholas G Martin Wendy L McArdle Mads Melbye Vincent Mooser Jeffrey C Murray Sarah S Murray Michael A Nalls Pau Navarro Mari Nelis Andrew R Ness Kate Northstone Ben A Oostra Munro Peacock Lyle J Palmer Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Leena Peltonen Craig E Pennell Paul Pharoah Ozren Polasek Andrew S Plump Anneli Pouta Eleonora Porcu Thorunn Rafnar John P Rice Susan M Ring Fernando Rivadeneira Igor Rudan Cinzia Sala Veikko Salomaa Serena Sanna David Schlessinger Nicholas J Schork Angelo Scuteri Ayellet V Segrè Alan R Shuldiner Nicole Soranzo Ulla Sovio Sathanur R Srinivasan David P Strachan Mar-Liis Tammesoo Emmi Tikkanen Daniela Toniolo Kim Tsui Laufey Tryggvadottir Jonathon Tyrer Manuela Uda Rob M van Dam Joyce B J van Meurs Peter Vollenweider Gerard Waeber Nicholas J Wareham Dawn M Waterworth Michael N Weedon H Erich Wichmann Gonneke Willemsen James F Wilson Alan F Wright Lauren Young Guangju Zhai Wei Vivian Zhuang Laura J Bierut Dorret I Boomsma Heather A Boyd Laura Crisponi Ellen W Demerath Cornelia M van Duijn Michael J Econs Tamara B Harris David J Hunter Ruth J F Loos Andres Metspalu Grant W Montgomery Paul M Ridker Tim D Spector Elizabeth A Streeten Kari Stefansson Unnur Thorsteinsdottir André G Uitterlinden Elisabeth Widen Joanne M Murabito Ken K Ong Anna Murray

Nat Genet 2010 Dec;42(12):1077-85

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1038/ng.714	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140055	PMC

December 2010

Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis.

Authors:

Hanneke J M Kerkhof Ingrid Meulenbelt Andrew Carr Antonio Gonzalez Deborah Hart Albert Hofman Margreet Kloppenburg Nancy E Lane John Loughlin Michael C Nevitt Huibert A P Pols Fernando Rivadeneira Eline P Slagboom Tim D Spector Lisette Stolk Aspasia Tsezou André G Uitterlinden Ana M Valdes Joyce B J van Meurs

BMC Med Genet 2010 Nov 16;11:164. Epub 2010 Nov 16.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF	Source
http://dx.doi.org/10.1186/1471-2350-11-164	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997092	PMC

November 2010

Joyce B van Meurs

Joyce B van Meurs

Publications by authors named "Joyce B van Meurs"

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors:

Download full-text PDF

Authors: