Josyf C Mychaleckyj

Josyf C Mychaleckyj

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Josyf C Mychaleckyj

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A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

Nat Commun 2019 01 3;10(1):29. Epub 2019 Jan 3.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC, 27516-8050, USA.

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http://www.nature.com/articles/s41467-018-07867-7
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http://dx.doi.org/10.1038/s41467-018-07867-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318312PMC
January 2019

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

Authors:
Victoria E Jackson Jeanne C Latourelle Louise V Wain Albert V Smith Megan L Grove Traci M Bartz Ma'en Obeidat Michael A Province Wei Gao Beenish Qaiser David J Porteous Patricia A Cassano Tarunveer S Ahluwalia Niels Grarup Jin Li Elisabeth Altmaier Jonathan Marten Sarah E Harris Ani Manichaikul Tess D Pottinger Ruifang Li-Gao Allan Lind-Thomsen Anubha Mahajan Lies Lahousse Medea Imboden Alexander Teumer Bram Prins Leo-Pekka Lyytikäinen Gudny Eiriksdottir Nora Franceschini Colleen M Sitlani Jennifer A Brody Yohan Bossé Wim Timens Aldi Kraja Anu Loukola Wenbo Tang Yongmei Liu Jette Bork-Jensen Johanne M Justesen Allan Linneberg Leslie A Lange Rajesh Rawal Stefan Karrasch Jennifer E Huffman Blair H Smith Gail Davies Kristin M Burkart Josyf C Mychaleckyj Tobias N Bonten Stefan Enroth Lars Lind Guy G Brusselle Ashish Kumar Beate Stubbe Mika Kähönen Annah B Wyss Bruce M Psaty Susan R Heckbert Ke Hao Taina Rantanen Stephen B Kritchevsky Kurt Lohman Tea Skaaby Charlotta Pisinger Torben Hansen Holger Schulz Ozren Polasek Archie Campbell John M Starr Stephen S Rich Dennis O Mook-Kanamori Åsa Johansson Erik Ingelsson André G Uitterlinden Stefan Weiss Olli T Raitakari Vilmundur Gudnason Kari E North Sina A Gharib Don D Sin Kent D Taylor George T O'Connor Jaakko Kaprio Tamara B Harris Oluf Pederson Henrik Vestergaard James G Wilson Konstantin Strauch Caroline Hayward Shona Kerr Ian J Deary R Graham Barr Renée de Mutsert Ulf Gyllensten Andrew P Morris M Arfan Ikram Nicole Probst-Hensch Sven Gläser Eleftheria Zeggini Terho Lehtimäki David P Strachan Josée Dupuis Alanna C Morrison Ian P Hall Martin D Tobin Stephanie J London

Wellcome Open Res 2018 12;3. Epub 2018 Jan 12.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Dept of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.12688/wellcomeopenres.12583.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081985PMC
January 2018

Delayed Dosing of Oral Rotavirus Vaccine Demonstrates Decreased Risk of Rotavirus Gastroenteritis Associated With Serum Zinc: A Randomized Controlled Trial.

Clin Infect Dis 2016 Sep 23;63(5):634-41. Epub 2016 May 23.

Department of Medicine, Vaccine Testing Center and Unit of Infectious Diseases, University of Vermont College of Medicine, Burlington.

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http://dx.doi.org/10.1093/cid/ciw346DOI Listing
September 2016

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.

Authors:
Elisabeth M van Leeuwen Aniko Sabo Joshua C Bis Jennifer E Huffman Ani Manichaikul Albert V Smith Mary F Feitosa Serkalem Demissie Peter K Joshi Qing Duan Jonathan Marten Jan B van Klinken Ida Surakka Ilja M Nolte Weihua Zhang Hamdi Mbarek Ruifang Li-Gao Stella Trompet Niek Verweij Evangelos Evangelou Leo-Pekka Lyytikäinen Bamidele O Tayo Joris Deelen Peter J van der Most Sander W van der Laan Dan E Arking Alanna Morrison Abbas Dehghan Oscar H Franco Albert Hofman Fernando Rivadeneira Eric J Sijbrands Andre G Uitterlinden Josyf C Mychaleckyj Archie Campbell Lynne J Hocking Sandosh Padmanabhan Jennifer A Brody Kenneth M Rice Charles C White Tamara Harris Aaron Isaacs Harry Campbell Leslie A Lange Igor Rudan Ivana Kolcic Pau Navarro Tatijana Zemunik Veikko Salomaa Angad S Kooner Jaspal S Kooner Benjamin Lehne William R Scott Sian-Tsung Tan Eco J de Geus Yuri Milaneschi Brenda W J H Penninx Gonneke Willemsen Renée de Mutsert Ian Ford Ron T Gansevoort Marcelo P Segura-Lepe Olli T Raitakari Jorma S Viikari Kjell Nikus Terrence Forrester Colin A McKenzie Anton J M de Craen Hester M de Ruijter Gerard Pasterkamp Harold Snieder Albertine J Oldehinkel P Eline Slagboom Richard S Cooper Mika Kähönen Terho Lehtimäki Paul Elliott Pim van der Harst J Wouter Jukema Dennis O Mook-Kanamori Dorret I Boomsma John C Chambers Morris Swertz Samuli Ripatti Ko Willems van Dijk Veronique Vitart Ozren Polasek Caroline Hayward James G Wilson James F Wilson Vilmundur Gudnason Stephen S Rich Bruce M Psaty Ingrid B Borecki Eric Boerwinkle Jerome I Rotter L Adrienne Cupples Cornelia M van Duijn

J Med Genet 2016 07 1;53(7):441-9. Epub 2016 Apr 1.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1136/jmedgenet-2015-103439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941146PMC
July 2016

Effect of substituting IPV for tOPV on immunity to poliovirus in Bangladeshi infants: An open-label randomized controlled trial.

Vaccine 2016 01 28;34(3):358-66. Epub 2015 Nov 28.

Division of Infectious Diseases and International Health, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.11.046DOI Listing
January 2016

Polio eradication: inching forward, with safety nets.

Lancet Infect Dis 2015 Nov 26;15(11):1244-5. Epub 2015 Aug 26.

Department of Public Health Sciences, University of Virginia, Charlottesville VA, USA.

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http://dx.doi.org/10.1016/S1473-3099(15)00261-3DOI Listing
November 2015

Fine mapping the region reveals a common intronic insertion associated to HDL-C.

NPJ Aging Mech Dis 2015 12;1:15011. Epub 2015 Nov 12.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/npjamd.2015.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514988PMC
November 2015

Plasma Levels of Soluble Interleukin-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan.

Arterioscler Thromb Vasc Biol 2015 Oct 20;35(10):2246-53. Epub 2015 Aug 20.

From the Departments of Pathology (P.D., N.S.J., M.C., R.P.T.), Medicine (M.C.), and Biochemistry (R.P.T.), University of Vermont College of Medicine, Burlington; Departments of Genetics (J.S., E.M.L., J.L., W.V., L.A.L.), Biostatistics (E.M.L., W.V.), Lineberger Comprehensive Cancer Center, School of Medicine (J.S., E.M.L., W.V.), University of North Carolina, Chapel Hill; Laboratory of Neurogenetics, Porter Neuroscience Research Center, National Institute on Aging, National Institute of Health, Bethesda, MD (M.A.N.); Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville (J.C.M.); Johns Hopkins Medical Institutions, Department of Medicine Geriatrics, Johns Hopkins University, John R. Burton Pavilion, Baltimore, MD (J.D.W.); Geriatric Epidemiology Section, National Institute on Aging, National Institute of Health, Bethesda, MD (T.B.H.); Cardiovascular Health Research Unit (B.M.P.), Departments of Medicine (B.M.P.) and Epidemiology (B.M.P., A.P.R.), University of Washington, Seattle; Group Health Research Institute, Division of Cardiology, Group Health Cooperative, Seattle, WA (B.M.P.); and Wake Forest University School of Medicine, Center for Genomics and Personalized Medicine Research, Winston-Salem, NC (Y.L.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395092PMC
October 2015

Differential Gene Expression in Diabetic Nephropathy in Individuals With Type 1 Diabetes.

J Clin Endocrinol Metab 2015 Jun 14;100(6):E876-82. Epub 2015 Apr 14.

Departments of Medicine and Pediatrics (M.L.C., M.M.), and Pediatrics and Laboratory Medicine and Pathology (Y.K.), University of Minnesota, Minneapolis, Minnesota 55455; Joslin Diabetes Center (A.B.G., A.S.K.), Harvard Medical School, Boston, Massachusetts 02115; Department of Genetics (J.H.M.), Institute for Biomedical Informatics, Department of Biostatistics and Epidemiology, Perelman School of Medicine, Dartmouth College, Hanover, New Hampshire 03755; Departments of Public Health Sciences (S.S.R.), and Bioinformatics and Genetics (J.C.M.), University of Virginia, Charlottesville, Virginia 22908; Department of Genetics (D.K.), Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455; and JDRF (H.N.), New York, New York 10004.

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http://dx.doi.org/10.1210/jc.2014-4465DOI Listing
June 2015

Differential Response to High Glucose in Skin Fibroblasts of Monozygotic Twins Discordant for Type 1 Diabetes.

J Clin Endocrinol Metab 2015 Jun 22;100(6):E883-9. Epub 2015 Apr 22.

Departments of Medicine and Pediatrics (M.L.C., M.M.) and Pediatrics and Laboratory Medicine and Pathology (Y.K.), University of Minnesota, Minneapolis, Minnesota 55455; Department of Diabetes Complications, Obesity and Metabolism (R.N.), Beckman Research Institute, City of Hope, Duarte, California 91010; Department of Genetics (J.H.M.), Dartmouth College, Hanover, New Hampshire 03755; Departments of Public Health Sciences (S.S.R.) and Bioinformatics and Genetics (J.C.M.), University of Virginia, Charlottesville, Virginia 22908; and Department of Genetics, Cell Biology and Development (R.K., D.K.), University of Minnesota, Minneapolis, Minnesota 55455.

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http://dx.doi.org/10.1210/jc.2014-4467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393515PMC
June 2015

The "Performance of Rotavirus and Oral Polio Vaccines in Developing Countries" (PROVIDE) study: description of methods of an interventional study designed to explore complex biologic problems.

Am J Trop Med Hyg 2015 Apr 23;92(4):744-51. Epub 2015 Feb 23.

Department of Medicine and Vaccine Testing Center, The University of Vermont College of Medicine, Burlington, Vermont; Departments of Medicine, The University of Virginia, Charlottesville, Virginia; The icddr,b, Dhaka, Bangladesh.

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http://dx.doi.org/10.4269/ajtmh.14-0518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385767PMC
April 2015

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels.

Nat Commun 2015 Mar 9;6:6065. Epub 2015 Mar 9.

Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands.

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http://dx.doi.org/10.1038/ncomms7065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366498PMC
March 2015

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.

PLoS Genet 2014 Aug 7;10(8):e1004517. Epub 2014 Aug 7.

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125087PMC
August 2014

Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.

Front Public Health 2014 6;2:112. Epub 2014 Aug 6.

Center for Public Health Genomics, University of Virginia , Charlottesville, VA , USA ; Department of Public Health Sciences, University of Virginia , Charlottesville, VA , USA ; Department of Biochemistry & Molecular Genetics, University of Virginia , Charlottesville, VA , USA.

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http://dx.doi.org/10.3389/fpubh.2014.00112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123605PMC
August 2014

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.

Authors:
Gina M Peloso Paul L Auer Joshua C Bis Arend Voorman Alanna C Morrison Nathan O Stitziel Jennifer A Brody Sumeet A Khetarpal Jacy R Crosby Myriam Fornage Aaron Isaacs Johanna Jakobsdottir Mary F Feitosa Gail Davies Jennifer E Huffman Ani Manichaikul Brian Davis Kurt Lohman Aron Y Joon Albert V Smith Megan L Grove Paolo Zanoni Valeska Redon Serkalem Demissie Kim Lawson Ulrike Peters Christopher Carlson Rebecca D Jackson Kelli K Ryckman Rachel H Mackey Jennifer G Robinson David S Siscovick Pamela J Schreiner Josyf C Mychaleckyj James S Pankow Albert Hofman Andre G Uitterlinden Tamara B Harris Kent D Taylor Jeanette M Stafford Lindsay M Reynolds Riccardo E Marioni Abbas Dehghan Oscar H Franco Aniruddh P Patel Yingchang Lu George Hindy Omri Gottesman Erwin P Bottinger Olle Melander Marju Orho-Melander Ruth J F Loos Stefano Duga Piera Angelica Merlini Martin Farrall Anuj Goel Rosanna Asselta Domenico Girelli Nicola Martinelli Svati H Shah William E Kraus Mingyao Li Daniel J Rader Muredach P Reilly Ruth McPherson Hugh Watkins Diego Ardissino Qunyuan Zhang Judy Wang Michael Y Tsai Herman A Taylor Adolfo Correa Michael E Griswold Leslie A Lange John M Starr Igor Rudan Gudny Eiriksdottir Lenore J Launer Jose M Ordovas Daniel Levy Y-D Ida Chen Alexander P Reiner Caroline Hayward Ozren Polasek Ian J Deary Ingrid B Borecki Yongmei Liu Vilmundur Gudnason James G Wilson Cornelia M van Duijn Charles Kooperberg Stephen S Rich Bruce M Psaty Jerome I Rotter Christopher J O'Donnell Kenneth Rice Eric Boerwinkle Sekar Kathiresan L Adrienne Cupples

Am J Hum Genet 2014 Feb;94(2):223-32

Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA; National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, MA 01702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928662PMC
February 2014

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

Authors:
Keri L Monda Gary K Chen Kira C Taylor Cameron Palmer Todd L Edwards Leslie A Lange Maggie C Y Ng Adebowale A Adeyemo Matthew A Allison Lawrence F Bielak Guanjie Chen Mariaelisa Graff Marguerite R Irvin Suhn K Rhie Guo Li Yongmei Liu Youfang Liu Yingchang Lu Michael A Nalls Yan V Sun Mary K Wojczynski Lisa R Yanek Melinda C Aldrich Adeyinka Ademola Christopher I Amos Elisa V Bandera Cathryn H Bock Angela Britton Ulrich Broeckel Quiyin Cai Neil E Caporaso Chris S Carlson John Carpten Graham Casey Wei-Min Chen Fang Chen Yii-Der I Chen Charleston W K Chiang Gerhard A Coetzee Ellen Demerath Sandra L Deming-Halverson Ryan W Driver Patricia Dubbert Mary F Feitosa Ye Feng Barry I Freedman Elizabeth M Gillanders Omri Gottesman Xiuqing Guo Talin Haritunians Tamara Harris Curtis C Harris Anselm J M Hennis Dena G Hernandez Lorna H McNeill Timothy D Howard Barbara V Howard Virginia J Howard Karen C Johnson Sun J Kang Brendan J Keating Suzanne Kolb Lewis H Kuller Abdullah Kutlar Carl D Langefeld Guillaume Lettre Kurt Lohman Vaneet Lotay Helen Lyon Joann E Manson William Maixner Yan A Meng Kristine R Monroe Imran Morhason-Bello Adam B Murphy Josyf C Mychaleckyj Rajiv Nadukuru Katherine L Nathanson Uma Nayak Amidou N'diaye Barbara Nemesure Suh-Yuh Wu M Cristina Leske Christine Neslund-Dudas Marian Neuhouser Sarah Nyante Heather Ochs-Balcom Adesola Ogunniyi Temidayo O Ogundiran Oladosu Ojengbede Olufunmilayo I Olopade Julie R Palmer Edward A Ruiz-Narvaez Nicholette D Palmer Michael F Press Evandine Rampersaud Laura J Rasmussen-Torvik Jorge L Rodriguez-Gil Babatunde Salako Eric E Schadt Ann G Schwartz Daniel A Shriner David Siscovick Shad B Smith Sylvia Wassertheil-Smoller Elizabeth K Speliotes Margaret R Spitz Lara Sucheston Herman Taylor Bamidele O Tayo Margaret A Tucker David J Van Den Berg Digna R Velez Edwards Zhaoming Wang John K Wiencke Thomas W Winkler John S Witte Margaret Wrensch Xifeng Wu James J Yang Albert M Levin Taylor R Young Neil A Zakai Mary Cushman Krista A Zanetti Jing Hua Zhao Wei Zhao Yonglan Zheng Jie Zhou Regina G Ziegler Joseph M Zmuda Jyotika K Fernandes Gary S Gilkeson Diane L Kamen Kelly J Hunt Ida J Spruill Christine B Ambrosone Stefan Ambs Donna K Arnett Larry Atwood Diane M Becker Sonja I Berndt Leslie Bernstein William J Blot Ingrid B Borecki Erwin P Bottinger Donald W Bowden Gregory Burke Stephen J Chanock Richard S Cooper Jingzhong Ding David Duggan Michele K Evans Caroline Fox W Timothy Garvey Jonathan P Bradfield Hakon Hakonarson Struan F A Grant Ann Hsing Lisa Chu Jennifer J Hu Dezheng Huo Sue A Ingles Esther M John Joanne M Jordan Edmond K Kabagambe Sharon L R Kardia Rick A Kittles Phyllis J Goodman Eric A Klein Laurence N Kolonel Loic Le Marchand Simin Liu Barbara McKnight Robert C Millikan Thomas H Mosley Badri Padhukasahasram L Keoki Williams Sanjay R Patel Ulrike Peters Curtis A Pettaway Patricia A Peyser Bruce M Psaty Susan Redline Charles N Rotimi Benjamin A Rybicki Michèle M Sale Pamela J Schreiner Lisa B Signorello Andrew B Singleton Janet L Stanford Sara S Strom Michael J Thun Mara Vitolins Wei Zheng Jason H Moore Scott M Williams Shamika Ketkar Xiaofeng Zhu Alan B Zonderman Charles Kooperberg George J Papanicolaou Brian E Henderson Alex P Reiner Joel N Hirschhorn Ruth J F Loos Kari E North Christopher A Haiman

Nat Genet 2013 Jun 14;45(6):690-6. Epub 2013 Apr 14.

The Center for Observational Research, Amgen, Inc. Thousand Oaks, California, USA.

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http://dx.doi.org/10.1038/ng.2608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694490PMC
June 2013

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Blood 2012 Dec 18;120(24):4873-81. Epub 2012 Sep 18.

National Heart, Lung, and Blood Institute (NHBLI) Framingham Heart Study, Framingham, MA 01702, USA.

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http://www.bloodjournal.org/content/120/24/4873.full.pdf
Web Search
http://atvb.ahajournals.org/content/34/5/1093.full.pdf
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-06-43
Publisher Site
http://dx.doi.org/10.1182/blood-2012-06-436188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520624PMC
December 2012

Gene expression differences in skin fibroblasts in identical twins discordant for type 1 diabetes.

Diabetes 2012 Mar 7;61(3):739-44. Epub 2012 Feb 7.

Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.2337/db11-0617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282806PMC
March 2012

Expression profiling reveals differential gene induction underlying specific and non-specific memory for pheromones in mice.

Neurochem Int 2011 Nov 23;59(6):787-803. Epub 2011 Aug 23.

Department of Neurobiology and Anatomy, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01970186110027
Publisher Site
http://dx.doi.org/10.1016/j.neuint.2011.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206202PMC
November 2011

Significant linkage at chromosome 19q for otitis media with effusion and/or recurrent otitis media (COME/ROM).

BMC Med Genet 2011 Sep 26;12:124. Epub 2011 Sep 26.

Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1186/1471-2350-12-124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191346PMC
September 2011

Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes.

Mol Genet Metab 2011 May 14;103(1):60-5. Epub 2011 Jan 14.

Research Division, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.ymgme.2011.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081941PMC
May 2011

CUBN is a gene locus for albuminuria.

Authors:
Carsten A Böger Ming-Huei Chen Adrienne Tin Matthias Olden Anna Köttgen Ian H de Boer Christian Fuchsberger Conall M O'Seaghdha Cristian Pattaro Alexander Teumer Ching-Ti Liu Nicole L Glazer Man Li Jeffrey R O'Connell Toshiko Tanaka Carmen A Peralta Zoltán Kutalik Jian'an Luan Jing Hua Zhao Shih-Jen Hwang Ermeg Akylbekova Holly Kramer Pim van der Harst Albert V Smith Kurt Lohman Mariza de Andrade Caroline Hayward Barbara Kollerits Anke Tönjes Thor Aspelund Erik Ingelsson Gudny Eiriksdottir Lenore J Launer Tamara B Harris Alan R Shuldiner Braxton D Mitchell Dan E Arking Nora Franceschini Eric Boerwinkle Josephine Egan Dena Hernandez Muredach Reilly Raymond R Townsend Thomas Lumley David S Siscovick Bruce M Psaty Bryan Kestenbaum Talin Haritunians Sven Bergmann Peter Vollenweider Gerard Waeber Vincent Mooser Dawn Waterworth Andrew D Johnson Jose C Florez James B Meigs Xiaoning Lu Stephen T Turner Elizabeth J Atkinson Tennille S Leak Knut Aasarød Frank Skorpen Ann-Christine Syvänen Thomas Illig Jens Baumert Wolfgang Koenig Bernhard K Krämer Olivier Devuyst Josyf C Mychaleckyj Cosetta Minelli Stephan J L Bakker Lyudmyla Kedenko Bernhard Paulweber Stefan Coassin Karlhans Endlich Heyo K Kroemer Reiner Biffar Sylvia Stracke Henry Völzke Michael Stumvoll Reedik Mägi Harry Campbell Veronique Vitart Nicholas D Hastie Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Ozren Polasek Gary Curhan Florian Kronenberg Inga Prokopenko Igor Rudan Johan Arnlöv Stein Hallan Gerjan Navis Afshin Parsa Luigi Ferrucci Josef Coresh Michael G Shlipak Shelley B Bull Nicholas J Paterson H-Erich Wichmann Nicholas J Wareham Ruth J F Loos Jerome I Rotter Peter P Pramstaller L Adrienne Cupples Jacques S Beckmann Qiong Yang Iris M Heid Rainer Rettig Albert W Dreisbach Murielle Bochud Caroline S Fox W H L Kao

J Am Soc Nephrol 2011 Mar;22(3):555-70

Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1681/ASN.2010060598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060449PMC
March 2011

Robust relationship inference in genome-wide association studies.

Bioinformatics 2010 Nov 5;26(22):2867-73. Epub 2010 Oct 5.

Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btq559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025716PMC
November 2010

Planning and executing a genome wide association study (GWAS).

Methods Mol Biol 2009 ;590:403-18

Department of Medicine, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1007/978-1-60327-378-7_25DOI Listing
January 2010

Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.

Diabetes 2009 Nov 3;58(11):2698-702. Epub 2009 Aug 3.

Research Division, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/db09-0641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768169PMC
November 2009

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

Nat Genet 2008 Dec 2;40(12):1399-401. Epub 2008 Nov 2.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635556PMC
December 2008

Genome mapping statistics and bioinformatics.

Methods Mol Biol 2007 ;404:461-88

Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1007/978-1-59745-530-5_22DOI Listing
May 2008

The intracellular form of human MAGP1 elicits a complex and specific transcriptional response.

Int J Biochem Cell Biol 2007 27;39(12):2303-13. Epub 2007 Jul 27.

Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.biocel.2007.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2083557PMC
January 2008

Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.

Diabetes 2007 Oct 29;56(10):2638-42. Epub 2007 Jun 29.

Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.2337/db07-0012DOI Listing
October 2007

Full length cloning and expression analysis of splice variants of regulator of G-protein signaling RGS4 in human and murine brain.

Gene 2007 Oct 14;401(1-2):46-60. Epub 2007 Jul 14.

Department of Neurobiology and Anatomy, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.gene.2007.07.002DOI Listing
October 2007

Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population.

Mol Genet Metab 2006 Jan 2;87(1):54-60. Epub 2005 Sep 2.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S109671920500224
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http://dx.doi.org/10.1016/j.ymgme.2005.07.013DOI Listing
January 2006

Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes.

Diabetes 2005 Apr;54(4):1185-90

Molecular Genetics Program, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.2337/diabetes.54.4.1185DOI Listing
April 2005

Pseudomonas aeruginosa flagellin and alginate elicit very distinct gene expression patterns in airway epithelial cells: implications for cystic fibrosis disease.

J Immunol 2004 Nov;173(9):5659-70

Department of Internal Medicine (Molecular Medicine), Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.173.9.5659DOI Listing
November 2004

Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.

Diabetes 2004 Nov;53(11):3007-12

Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.2337/diabetes.53.11.3007DOI Listing
November 2004

Comparative genomic analysis of the HNF-4alpha transcription factor gene.

Mol Genet Metab 2004 Feb;81(2):112-21

Department of Biochemistry, Wake Forest University, School of Medicine, Winston-Salem, NC 27157, USA.

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February 2004

Nucleotide variation, haplotype structure, and association with end-stage renal disease of the human interleukin-1 gene cluster.

Genomics 2003 Aug;82(2):194-217

The Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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August 2003

Ambulatory Care Skills: Do Residents Feel Prepared?

Med Educ Online 2002 Dec;7(1):4536

a Department of Internal Medicine, Section on General Internal Medicine.

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http://dx.doi.org/10.3402/meo.v7i.4536DOI Listing
December 2002