Publications by authors named "Josiane Lafleur"

23Publications

Prognostic and predictive value of circulating tumor DNA during neoadjuvant chemotherapy for triple negative breast cancer.

Authors:
Luca Cavallone Adriana Aguilar-Mahecha Josiane Lafleur Susie Brousse Mohammed Aldamry Talia Roseshter Cathy Lan Najmeh Alirezaie Eric Bareke Jacek Majewski Cristiano Ferrario Saima Hassan Federico Discepola Carole Seguin Catalin Mihalcioiu Elizabeth A Marcus André Robidoux Josée-Anne Roy Manuela Pelmus Mark Basik

Sci Rep 2020 09 7;10(1):14704. Epub 2020 Sep 7.

Lady Davis Institute, Jewish General Hospital, Montreal, QC, H3T 1E2, Canada.

View Article and Find Full Text PDF
September 2020

Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors.

Authors:
Paul Savage Alain Pacis Hellen Kuasne Leah Liu Daniel Lai Adrian Wan Matthew Dankner Constanza Martinez Valentina Muñoz-Ramos Virginie Pilon Anie Monast Hong Zhao Margarita Souleimanova Matthew G Annis Adriana Aguilar-Mahecha Josiane Lafleur Nicholas R Bertos Jamil Asselah Nathaniel Bouganim Kevin Petrecca Peter M Siegel Atilla Omeroglu Sohrab P Shah Samuel Aparicio Mark Basik Sarkis Meterissian Morag Park

Commun Biol 2020 Jun 16;3(1):310. Epub 2020 Jun 16.

Rosalind & Morris Goodman Cancer Research Centre, McGill University, Montréal, QC, H3A 1A3, Canada.

View Article and Find Full Text PDF
June 2020

A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability.

Authors:
Isabelle Sirois Adriana Aguilar-Mahecha Josiane Lafleur Emma Fowler Viet Vu Michelle Scriver Marguerite Buchanan Catherine Chabot Aparna Ramanathan Banujan Balachandran Stéphanie Légaré Ewa Przybytkowski Cathy Lan Urszula Krzemien Luca Cavallone Olga Aleynikova Cristiano Ferrario Marie-Christine Guilbert Naciba Benlimame Amine Saad Moulay Alaoui-Jamali Horace Uri Saragovi Sylvia Josephy Ciara O'Flanagan Stephen D Hursting Vincent R Richard René P Zahedi Christoph H Borchers Eric Bareke Sheida Nabavi Peter Tonellato Josée-Anne Roy André Robidoux Elizabeth A Marcus Catalin Mihalcioiu Jacek Majewski Mark Basik

Mol Cancer Res 2019 12 19;17(12):2492-2507. Epub 2019 Sep 19.

Segal Cancer Center, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montréal, Québec, Canada.

View Article and Find Full Text PDF
December 2019

Metastatic Breast Carcinoma-Associated Fibroblasts Have Enhanced Protumorigenic Properties Related to Increased IGF2 Expression.

Authors:
Yirui Gui Adriana Aguilar-Mahecha Urszula Krzemien Abdel Hosein Marguerite Buchanan Josiane Lafleur Michael Pollak Cristiano Ferrario Mark Basik

Clin Cancer Res 2019 12 12;25(23):7229-7242. Epub 2019 Sep 12.

Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Canada.

View Article and Find Full Text PDF
December 2019

A Study of Pre-Analytical Variables and Optimization of Extraction Method for Circulating Tumor DNA Measurements by Digital Droplet PCR.

Authors:
Luca Cavallone Mohammed Aldamry Josiane Lafleur Cathy Lan Pablo Gonzalez Ginestet Najmeh Alirezaie Cristiano Ferrario Adriana Aguilar-Mahecha Mark Basik

Cancer Epidemiol Biomarkers Prev 2019 05 1;28(5):909-916. Epub 2019 Mar 1.

Department of Oncology, Lady Davis Institute, McGill University, Montreal, Quebec, Canada.

View Article and Find Full Text PDF
May 2019

Fabrication of Biomolecule Microarrays Using Rapid Photochemical Surface Patterning in Thiol-Ene-Based Microfluidic Devices.

Authors:
Alexander Jönsson Josiane P Lafleur

Methods Mol Biol 2018 ;1771:171-182

Faculty of Technical Chemistry, Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria.

View Article and Find Full Text PDF
February 2019

On-a-chip tryptic digestion of transthyretin: a step toward an integrated microfluidic system for the follow-up of familial transthyretin amyloidosis.

Authors:
Jeanne Bataille Arthur Viodé Iago Pereiro Josiane P Lafleur Fanny Varenne Stéphanie Descroix François Becher Jörg P Kutter Camille Roesch Christian Poüs Myriam Taverna Antoine Pallandre Claire Smadja Isabelle Le Potier

Analyst 2018 Feb;143(5):1077-1086

Faculté de Pharmacie, Université Paris-Sud, Université Paris-Saclay, Châtenay-Malabry, France.

View Article and Find Full Text PDF
February 2018

The identification of challenges in tissue collection for biomarker studies: the Q-CROC-03 neoadjuvant breast cancer translational trial experience.

Authors:
Adriana Aguilar-Mahecha Josiane Lafleur Manuela Pelmus Carole Seguin Cathy Lan Federico Discepola Bojan Kovacina Rosa Christodoulopoulos Ombretta Salvucci Catalin Mihalcioiu Josée-Anne Roy André Robidoux Elizabeth A Marcus Gerald Batist Mark Basik

Mod Pathol 2017 11 28;30(11):1567-1576. Epub 2017 Jul 28.

Department of Oncology, Lady Davis Institute, McGill University, Montreal, QC, Canada.

View Article and Find Full Text PDF
November 2017

Thiol-ene Monolithic Pepsin Microreactor with a 3D-Printed Interface for Efficient UPLC-MS Peptide Mapping Analyses.

Authors:
Alexander Jönsson Rasmus R Svejdal Nanna Bøgelund Tam T T N Nguyen Henrik Flindt Jörg P Kutter Kasper D Rand Josiane P Lafleur

Anal Chem 2017 04 4;89(8):4573-4580. Epub 2017 Apr 4.

Department of Pharmacy, Copenhagen University , Universitetsparken 2, Copenhagen E DK-2100, Denmark.

View Article and Find Full Text PDF
April 2017

Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study.

Authors:
Aghiad Ghazal Mark Gontsarik Jörg P Kutter Josiane P Lafleur Davoud Ahmadvand Ana Labrador Stefan Salentinig Anan Yaghmur

J Phys Chem Lett 2017 Jan 12;8(1):73-79. Epub 2016 Dec 12.

Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.

View Article and Find Full Text PDF
January 2017

Recent advances in X-ray compatible microfluidics for applications in soft materials and life sciences.

Authors:
Aghiad Ghazal Josiane P Lafleur Kell Mortensen Jörg P Kutter Lise Arleth Grethe V Jensen

Lab Chip 2016 11;16(22):4263-4295

Niels Bohr Institute, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark.

View Article and Find Full Text PDF
November 2016

Recent advances in lab-on-a-chip for biosensing applications.

Authors:
Josiane P Lafleur Alexander Jönsson Silja Senkbeil Jörg P Kutter

Biosens Bioelectron 2016 Feb 13;76:213-33. Epub 2015 Aug 13.

Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark. Electronic address:

View Article and Find Full Text PDF
February 2016

Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors.

Authors:
Josiane P Lafleur Silja Senkbeil Jakub Novotny Gwenaël Nys Nanna Bøgelund Kasper D Rand Frantisek Foret Jörg P Kutter

Lab Chip 2015 May;15(10):2162-72

Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.

View Article and Find Full Text PDF
May 2015

Consent for nondiagnostic research biopsies: a pilot study of participant recall and therapeutic orientation.

Authors:
Roberto Abadie Jonathan Kimmelman Josiane Lafleur Trudo Lemmens

IRB 2014 May-Jun;36(3):9-15

View Article and Find Full Text PDF
July 2014

Surface functionalized thiol-ene waveguides for fluorescence biosensing in microfluidic devices.

Authors:
Nikolaj A Feidenhans'l Josiane P Lafleur Thomas G Jensen Jörg P Kutter

Electrophoresis 2014 Feb 7;35(2-3):282-8. Epub 2013 Oct 7.

Department of Micro- and Nanotechnology, Technical University of Denmark, Kongens Lyngby, Denmark.

View Article and Find Full Text PDF
February 2014

Rapid photochemical surface patterning of proteins in thiol-ene based microfluidic devices.

Authors:
Josiane P Lafleur Radoslaw Kwapiszewski Thomas G Jensen Jörg P Kutter

Analyst 2013 Feb 29;138(3):845-9. Epub 2012 Nov 29.

Department of Micro- and Nanotechnology, Technical University of Denmark, DK-2800 Kgs Lyngby, Denmark.

View Article and Find Full Text PDF
February 2013

Gold nanoparticle-based optical microfluidic sensors for analysis of environmental pollutants.

Authors:
Josiane P Lafleur Silja Senkbeil Thomas G Jensen Jörg P Kutter

Lab Chip 2012 Nov;12(22):4651-6

Technical University of Denmark, Department of Micro- and Nanotechnology, Ørsteds Plads Bldg 345B, Kgs. Lyngby, Denmark.

View Article and Find Full Text PDF
November 2012

Broadening the spectrum of β-lactam antibiotics through inhibition of signal peptidase type I.

Authors:
Alex G Therien Joann L Huber Kenneth E Wilson Patrick Beaulieu Alexandre Caron David Claveau Kathleen Deschamps Robert G K Donald Andrew M Galgoci Michel Gallant Xin Gu Nancy J Kevin Josiane Lafleur Penny S Leavitt Christian Lebeau-Jacob Suzy S Lee Molly M Lin Anna A Michels Aimie M Ogawa Ronald E Painter Craig A Parish Young-Whan Park Liliana Benton-Perdomo Mihai Petcu John W Phillips Mary Ann Powles Kathryn I Skorey John Tam Christopher M Tan Katherine Young Simon Wong Sherman T Waddell Lynn Miesel

Antimicrob Agents Chemother 2012 Sep 18;56(9):4662-70. Epub 2012 Jun 18.

Merck Frosst Centre for Therapeutic Research, Kirkland, Quebec, Canada.

View Article and Find Full Text PDF
September 2012

Miniaturised centrifugal solid phase extraction platforms for in-field sampling, pre-concentration and spectrometric detection of organic pollutants in aqueous samples.

Authors:
Josiane P Lafleur Andrien A Rackov Scott McAuley Eric D Salin

Talanta 2010 Apr 16;81(1-2):722-6. Epub 2009 Dec 16.

Department of Chemistry, McGill University, 801 Sherbrooke St W., Montreal, Qc, Canada.

View Article and Find Full Text PDF
April 2010

The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration.

Authors:
Chun Yang Josiane Lafleur Bupe R Mwaikambo Tang Zhu Carmen Gagnon Sylvain Chemtob Adriana Di Polo Pierre Hardy

Invest Ophthalmol Vis Sci 2009 Mar 31;50(3):1290-8. Epub 2008 Oct 31.

Department of Paediatrics, Research Center of Sainte-Justine Hospital, University of Montreal, Montreal, Quebec, Canada.

View Article and Find Full Text PDF
March 2009

Speciation of chromium by high-performance thin-layer chromatography with direct determination by laser ablation inductively coupled plasma mass spectrometry.

Authors:
Josiane P Lafleur Eric D Salin

Anal Chem 2008 Sep 6;80(17):6821-3. Epub 2008 Aug 6.

View Article and Find Full Text PDF
September 2008

Adenovirus IL-13-induced airway disease in mice: a corticosteroid-resistant model of severe asthma.

Authors:
Alex G Therien Virginie Bernier Sean Weicker Paul Tawa Jean-Pierre Falgueyret Marie-Claude Mathieu Jeanne Honsberger Véronique Pomerleau Annette Robichaud Rino Stocco Lynn Dufresne Hani Houshyar Josiane Lafleur Chidambaram Ramachandran Gary P O'Neill Deborah Slipetz Christopher M Tan

Am J Respir Cell Mol Biol 2008 Jul 7;39(1):26-35. Epub 2008 Feb 7.

Merck Frosst Centre for Therapeutic Research, 16711 Trans Canada Highway, Kirkland, Quebec, Canada.

View Article and Find Full Text PDF
July 2008

Lymphocytic microparticles inhibit angiogenesis by stimulating oxidative stress and negatively regulating VEGF-induced pathways.

Authors:
Chun Yang Bupe R Mwaikambo Tang Zhu Carmen Gagnon Josiane Lafleur Swathi Seshadri Pierre Lachapelle Jean-Claude Lavoie Sylvain Chemtob Pierre Hardy

Am J Physiol Regul Integr Comp Physiol 2008 Feb 28;294(2):R467-76. Epub 2007 Nov 28.

Research Center of CHU Sainte-Justine, 3175 Côte-Sainte-Catherine,Montreal, Quebec, Canada.

View Article and Find Full Text PDF
February 2008