Joshua M Hare

Joshua M Hare

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Joshua M Hare

Publications by authors named "Joshua M Hare"

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Progenitor/Stem Cell Delivery by Suprarenal Aorta Route in Acute Kidney Injury.

Cell Transplant 2019 Nov 13;28(11):1390-1403. Epub 2019 Aug 13.

Interdisciplinary Stem Cell Institute, Leonard M Miller School of Medicine, University of Miami, USA.

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http://dx.doi.org/10.1177/0963689719860826DOI Listing
November 2019

Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial.

Neurology 2019 Oct 4;93(14):e1328-e1338. Epub 2019 Sep 4.

From the Departments of Neurology (M.A.S., R.B., S.B., R.L., A.Y.H., G.B.) and Medicine (E.A.M.), Massachusetts General Hospital, Boston; University of Cincinnati (A.J.E.), OH; Rush University (C.G.G.), Chicago, IL; Michigan State University (J.L.G.), East Lansing; Struthers Parkinson's Center (S.A.P.), Minneapolis, MN; Boston University (M.H.S.-H.), MA; University of Rochester (A.R.), NY; University of Miami (J.M.H.), FL; Brigham and Women's Hospital (G.C.C.), Boston, MA; Yale University School of Medicine (D.S.R.), New Haven, CT; and Department of Nutrition (A.A.), Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000008194DOI Listing
October 2019

Mesenchymal Stem Cell Secretion of SDF-1α Modulates Endothelial Function in Dilated Cardiomyopathy.

Front Physiol 2019 24;10:1182. Epub 2019 Sep 24.

Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.

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http://dx.doi.org/10.3389/fphys.2019.01182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769040PMC
September 2019

Regenerative Medicine and the Biology of Aging.

J Gerontol A Biol Sci Med Sci 2019 Aug;74(9):1339-1340

Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glz132DOI Listing
August 2019

Actions and Potential Therapeutic Applications of Growth Hormone-Releasing Hormone Agonists.

Endocrinology 2019 Jul;160(7):1600-1612

Department of Ophthalmology, Medical College of Georgia, Augusta University, Augusta, Georgia.

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http://dx.doi.org/10.1210/en.2019-00111DOI Listing
July 2019

Attenuation of frailty in older adults with mesenchymal stem cells.

Mech Ageing Dev 2019 Jul 7;181:47-58. Epub 2019 Jun 7.

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, United States; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2019.111120DOI Listing
July 2019

Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway.

J Am Coll Cardiol 2019 Jun;73(21):2705-2718

Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, Miami, Florida; Department of Medicine, Division of Cardiology, University of Miami Leonard M. Miller School of Medicine, Miami, Florida; Vascular Biology Institute and Peggy and Harold Katz Family Drug Discovery Center, University of Miami Leonard M. Miller School of Medicine, Miami, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.02.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546303PMC
June 2019

Cell-Based Therapy Restores Olfactory Function in an Inducible Model of Hyposmia.

Stem Cell Reports 2019 Jun 30;12(6):1354-1365. Epub 2019 May 30.

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, 1501 NW 10th Avenue, Biomedical Research Building, Room 809, Miami, FL 33136, USA; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA; Graduate Program in Neurosciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565856PMC
June 2019

Tumor Suppressors RB1 and CDKN2a Cooperatively Regulate Cell-Cycle Progression and Differentiation During Cardiomyocyte Development and Repair.

Circ Res 2019 Apr;124(8):1184-1197

From the Interdisciplinary Stem Cell Institute (K.E.H., A.R.W., M.A.B., W.Y., J.M.H.), University of Miami, Miller School of Medicine, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314063DOI Listing
April 2019

Rethinking Endothelial Dysfunction as a Crucial Target in Fighting Heart Failure.

Mayo Clin Proc Innov Qual Outcomes 2019 Mar 26;3(1):1-13. Epub 2019 Feb 26.

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL.

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http://dx.doi.org/10.1016/j.mayocpiqo.2018.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408687PMC
March 2019

Clinical and Neurophysiological Changes after Targeted Intrathecal Injections of Bone Marrow Stem Cells in a C3 Tetraplegic Subject.

J Neurotrauma 2019 Feb 23;36(3):500-516. Epub 2018 Jul 23.

1 The Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1089/neu.2018.5716DOI Listing
February 2019

Subcutaneous Leydig Stem Cell Autograft: A Promising Strategy to Increase Serum Testosterone.

Stem Cells Transl Med 2019 Jan 2;8(1):58-65. Epub 2018 Oct 2.

Department of Urology, Miller School of Medicine, University of Miami, Miami, Florida, USA.

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http://doi.wiley.com/10.1002/sctm.18-0069
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http://dx.doi.org/10.1002/sctm.18-0069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312442PMC
January 2019

Mesenchymal Stem Cell Therapy for Aging Frailty.

Front Nutr 2018 15;5:108. Epub 2018 Nov 15.

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, United States.

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http://dx.doi.org/10.3389/fnut.2018.00108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249304PMC
November 2018

Kidney-derived c-kit progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria.

Sci Rep 2018 10 3;8(1):14723. Epub 2018 Oct 3.

Interdisciplinary Stem Cell Institute, Leonard M Miller School of Medicine University of Miami, Miami, 33136, Florida, USA.

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http://www.nature.com/articles/s41598-018-33082-x
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http://dx.doi.org/10.1038/s41598-018-33082-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170432PMC
October 2018

Alterations of tumor microenvironment by nitric oxide impedes castration-resistant prostate cancer growth.

Proc Natl Acad Sci U S A 2018 10 15;115(44):11298-11303. Epub 2018 Oct 15.

Department of Urology, Miller School of Medicine, University of Miami, Miami, FL 33136;

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http://dx.doi.org/10.1073/pnas.1812704115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217394PMC
October 2018

Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine.

Circ Res 2018 10;123(9):1030-1032

From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.310426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289183PMC
October 2018

Mesenchymal Stem Cell-Based Therapy for Cardiovascular Disease: Progress and Challenges.

Mol Ther 2018 07 25;26(7):1610-1623. Epub 2018 May 25.

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037203PMC
July 2018

S-Nitrosoglutathione Reductase (GSNOR) Deficiency Results in Secondary Hypogonadism.

J Sex Med 2018 05 30;15(5):654-661. Epub 2018 Mar 30.

Department of Urology, University of Miami, Miami, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jsxm.2018.03.002DOI Listing
May 2018

Kidney-Derived c-Kit Cells Possess Regenerative Potential.

Stem Cells Transl Med 2018 04;7(4):317-324

Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1002/sctm.17-0232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866938PMC
April 2018

Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis.

Arterioscler Thromb Vasc Biol 2018 03 18;38(3):610-621. Epub 2018 Jan 18.

From the Department of Neurological Surgery & Radiology, University of Miami Cerebrovascular Initiative (R.M.S., J.W.T.), Department of Biochemistry and Molecular Biology (M.T.), and Department of Cardiology and Molecular and Cellular Pharmacology (J.M.H.), University of Miami, FL; Department of Neurosurgery, University of Iowa, Iowa City (M.S.A., D.M.H.); Department of Neurological Surgery, Tulane University, New Orleans, LA (C.L.P., A.M.L., A.S.D.); Department of Neurosurgery (D.D.) and Department of Molecular Physiology & Biophysics, Robert M. Berne Cardiovascular Research Center (G.K.O.), University of Virginia, Charlottesville; and Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA (N.C., P.J.).

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http://dx.doi.org/10.1161/ATVBAHA.117.310478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823774PMC
March 2018

Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility.

Circ Res 2018 03 15;122(7):933-944. Epub 2018 Feb 15.

From the Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY (J.M., D.K.C., P.A.G., P.M., J.F.M., S.I.S., F.S., S.S., R.J.H., K.D.C.); and Interdisciplinary Stem Cell Institute, Department of Cardiology, University of Miami Miller School of Medicine, Miami, FL (J.M.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.312420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986183PMC
March 2018

Preclinical Studies of Stem Cell Therapy for Heart Disease.

Circ Res 2018 03;122(7):1006-1020

From the Interdisciplinary Stem Cell Institute (B.A.T., W.B., J.M.H.), Department of Surgery (B.A.T.), and Department of Medicine (W.B., J.M.H.), University of Miami Miller School of Medicine, FL; Department of Cardiology, Medical University of Vienna, Austria (J.W., M.G., G.G.); Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense, Madrid, Spain (F.F.-A.); and CIBERCV, ISCIII, Madrid, Spain (F.F.-A.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.117.31248
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http://dx.doi.org/10.1161/CIRCRESAHA.117.312486DOI Listing
March 2018

Response.

Chest 2018 01;153(1):287-288

Department of Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, FL.

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http://dx.doi.org/10.1016/j.chest.2017.10.036DOI Listing
January 2018

Mesenchymal Stem Cells in Cardiology.

Methods Mol Biol 2016 ;1416:55-87

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, 1501 N.W. 10th Avenue, Miami, FL, 33136, USA.

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http://link.springer.com/10.1007/978-1-4939-3584-0_4
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http://dx.doi.org/10.1007/978-1-4939-3584-0_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720687PMC
December 2017

Dose Comparison Study of Allogeneic Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy (The TRIDENT Study).

Circ Res 2017 Nov 18;121(11):1279-1290. Epub 2017 Sep 18.

From the Interdisciplinary Stem Cell Institute (V.F., A.C.R., M.N., M.N.B., B.A.T., A.K., I.H.S., A.M.L., S.G., K.V., M.V.P., C.D., F.A., M.V.-C., R.G.S., D.D., L.V.C., K.N.R., A.W.H., R.D.M., J.M.H.), Department of Surgery (M.N.B., B.A.T., S.G.), Katz Family Division of Nephrology and Hypertension (I.H.S.), Department of Medicine (M.M., M.H.L., J.J.B., R.C.H., M.G.C., R.M., R.D.M., J.M.H.), and Department of Radiology (E.G.), University of Miami Miller School of Medicine, FL; The Emmes Corporation, Rockville, MD (J.E.-K., A.M.); and Longeveron LLC, Miami, FL (D.L.D.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311827DOI Listing
November 2017

New insights into cell-based therapy for heart failure from the CHART-1 study.

Eur J Heart Fail 2017 11 25;19(11):1530-1533. Epub 2017 Sep 25.

The Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1002/ejhf.955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796677PMC
November 2017

Differential expression of microRNAs among cell populations in the regenerating adult mouse olfactory epithelium.

PLoS One 2017 6;12(11):e0187576. Epub 2017 Nov 6.

Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187576PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673187PMC
November 2017

Inflammatory Cardiomyopathic Syndromes.

Circ Res 2017 Sep;121(7):803-818

From the Houston Methodist DeBakey Heart and Vascular Center (B.H.T.), TX; University of Miami Leonard Miller School of Medicine, FL (J.M.H.); and Interdisciplinary Stem Cell Institute, Miami, FL (J.M.H.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.117.31022
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.117.310221DOI Listing
September 2017

Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity.

Circ Res 2017 Aug 22;121(4):411-423. Epub 2017 Jun 22.

From the Cardiovascular Research Center (J.M., T.J.C., D.K.C., D.S., S.S., R.J.H., K.D.C.), Department of Developmental and Regenerative Biology (D.A.K.), and Department of Pharmacology and Systems Therapeutics (E.A.S.), Icahn School of Medicine at Mount Sinai, New York; Department of Medicine, University of Washington Seattle (B.V.J.); and The Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL (J.M.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899516PMC
August 2017

Evidence for a retinal progenitor cell in the postnatal and adult mouse.

Stem Cell Res 2017 08 24;23:20-32. Epub 2017 Jun 24.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450801PMC
August 2017

Cardiomyocyte Regeneration: A Consensus Statement.

Circulation 2017 08 6;136(7):680-686. Epub 2017 Jul 6.

From Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, Hamburg, Germany (T.E.); DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany (T.E.) and partner site Rhein/Main, Bad Nauheim, Germany (T.B.); Institute of Molecular Cardiology, University of Louisville, Louisville, KY (R.B.); Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany (T.B.); Department of Internal Medicine II, University of Giessen, Germany (T.B.); German Center for Lung Research (DZHL), Giessen/Marburg Bad Nauheim, Bad Nauheim, Germany (T.B.); Krannert Institute of Cardiology and Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis (L.J.F.); Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Germany (B.K.F.); Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden (J.F.); International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy (M.G.); Donald Soffer Endowed Program in Regenerative Medicine, Miller School of Medicine, Miami, FL (J.M.H.); Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (J.M.H.); Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA (S.H.); Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA (R.T.L.); Cedars-Sinai Heart Institute, Los Angeles, CA (E.M.); Cardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston (J.F.M.); Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX (J.F.M.); Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, OH (J.D.M.); Departments of Pathology, Bioengineering, and Medicine/Cardiology, Institute for Stem Cell and Regenerative Medicine, and Center for Cardiovascular Biology, University of Washington, Seattle (C.E.M.); University of Oxford, Department of Physiology, Anatomy and Genetics, United Kingdom (P.R.R.) Regencor, Inc, Los Altos, CA (P.R.-L.); Departments of Internal Medicine (Division of Cardiology) and Molecular Biology, UT Southwestern Medical Center, Dallas, TX (H.A.S., J.A.H.); and Heart Institute, Integrated Regenerative Research Institute, and Biology Department, San Diego State University, CA (M.S.A.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557671PMC
August 2017

Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering.

J Am Coll Cardiol 2017 Aug;70(6):766-775

Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, Alabama. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553556PMC
August 2017

Peripheral Blood Cytokine Levels After Acute Myocardial Infarction: IL-1β- and IL-6-Related Impairment of Bone Marrow Function.

Circ Res 2017 Jun 10;120(12):1947-1957. Epub 2017 May 10.

From the Department of Medicine, College of Medicine, University of Florida, Gainesville (M.S., E.W., J.J.S., J.Z., C.J.P., C.R.C.); Regenerative Medicine Research, Texas Heart Institute, CHI St. Luke's Health Baylor College of Medicine Medical Center, Houston (M.R., D.A.T.); Department of Medicine, University of Louisville, KY (R.B.); Department of Cardiovascular Sciences, Methodist DeBakey Heart and Vascular Center, the Houston Methodist Research Institute, TX (J.P.C.); Interdisciplinary Stem Cell Institute, University of Miami School of Medicine, FL (J.M.H., A.K.); Department of Medicine, Cedars-Sinai Heart Institute, Los Angeles, CA (T.D.H.); Department of Cardiology, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, MN (J.H.T.); and Department of Cardiovascular Medicine, Stanford University, School of Medicine, CA (P.C.Y.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508725PMC
June 2017

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).

Circulation 2017 Apr 16;135(15):1417-1428. Epub 2017 Feb 16.

From Texas Heart Institute (E.C.P., J.T.W., A.G., D.A.T., M.R., B.C., N.P.), CHI St. Luke's Health (R.M.), Houston; Indiana University School of Medicine, Indianapolis (M.P.M., K.L.M., P.G.); University of Louisville, KY (R.B., J.L., S.W.); Stanford University School of Medicine, CA (P.C.Y., N.J.L., R.L.D., F.K., E.G.R., M.R.S.); Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, MN (J.A., J.H.T., J.G.); Cedars-Sinai Heart Institute, Los Angeles, CA (T.D.H.); University of Florida School of Medicine, Gainesville (C.J.P., R.D.A., S.B., D.L., E.H.); University of Minnesota Medical School, Minneapolis (G.R., B.B.-D., E.C., A.T.H.); University of Miami Miller School of Medicine, FL (O.V., J.M.H., I.H.S., D.D.); Orlando Health, FL (V.S.K.); University of Colorado School of Medicine and CPC Clinical Research, Aurora (W.R.H.); Johns Hopkins University, Baltimore, MD (B.A.- V., J.A.L.); Baylor College of Medicine, Houston, TX (A.P.G., A.G.D., J. Bloom, S.R.); University of Texas School of Public Health, Houston (J. Bettencourt, D.L., L.P., L.S., M.C., S.L.S., R.W.V., L.M.); National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD (R.F.E.); and University of Kansas School of Medicine, Kansas City (R.D.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388585PMC
April 2017

Route of Delivery Modulates the Efficacy of Mesenchymal Stem Cell Therapy for Myocardial Infarction: A Meta-Analysis of Preclinical Studies and Clinical Trials.

Circ Res 2017 Mar 28;120(7):1139-1150. Epub 2016 Dec 28.

From the Interdisciplinary Stem Cell Institute (A.J.K., C.P., W.B., J.M.H.), Department of Molecular and Cellular Pharmacology (C.P.), and Department of Medicine (W.B., J.M.H.), University of Miami Miller School of Medicine, FL; and Florida International University Herbert Wertheim College of Medicine, Miami (J.L.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656247PMC
March 2017

The quest for a successful cell-based therapeutic approach for heart failure.

Eur Heart J 2017 03;38(9):661-664

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1093/eurheartj/ehw626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515521PMC
March 2017

GSNOR Deficiency Enhances In Situ Skeletal Muscle Strength, Fatigue Resistance, and RyR1 S-Nitrosylation Without Impacting Mitochondrial Content and Activity.

Antioxid Redox Signal 2017 02 19;26(4):165-181. Epub 2016 Aug 19.

1 Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine , Miami, Florida.

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http://dx.doi.org/10.1089/ars.2015.6548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278832PMC
February 2017

Next-Generation Stem Cell Therapy: Genetically Modified Mesenchymal Stem Cells for Cardiac Repair : Editorial to: "Mesenchymal Stem Cells with eNOS Over-Expression Enhance Cardiac Repair in Rats with Myocardial Infarction" by Leilei Chen et al.

Cardiovasc Drugs Ther 2017 02;31(1):5-7

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, P.O Box 016960 (R125), Biomedical Research Building, 1501 N.W. 10th Ave. Room 908, Miami, FL, 33136, USA.

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http://link.springer.com/10.1007/s10557-017-6714-5
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http://dx.doi.org/10.1007/s10557-017-6714-5DOI Listing
February 2017

What Is the Future of Cell-Based Therapy for Acute Myocardial Infarction.

Circ Res 2017 01;120(2):252-255

From The Interdisciplinary Stem Cell Institute (B.A.T., M.N., W.B., J.M.H.), Department of Surgery (B.A.T.), and Department of Medicine (W.B., J.M.H.), University of Miami Miller School of Medicine, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261616PMC
January 2017

Contribution of Polycomb group proteins to olfactory basal stem cell self-renewal in a novel c-KIT+ culture model and in vivo.

Development 2016 12 27;143(23):4394-4404. Epub 2016 Oct 27.

Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.1242/dev.142653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201051PMC
December 2016

Pim1 Kinase Overexpression Enhances ckit Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine.

J Am Coll Cardiol 2016 Dec;68(22):2454-2464

The Interdisciplinary Stem Cell Institute, University of Miami, Miller School of Medicine, Miami, Florida; Department of Medicine, University of Miami, Miller School of Medicine, Miami, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.09.925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223744PMC
December 2016

Stimulatory Effects of Mesenchymal Stem Cells on cKit+ Cardiac Stem Cells Are Mediated by SDF1/CXCR4 and SCF/cKit Signaling Pathways.

Circ Res 2016 Sep 1;119(8):921-30. Epub 2016 Aug 1.

From the Interdisciplinary Stem Cell Institute, University of Miami, Miller School of Medicine, FL (K.E.H., W.B., M.B., K.V., L.M.T., A.M.L., A.K., J.M.H.); Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, Germany (D.S., B.S.); and German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany (D.S., B.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180614PMC
September 2016

Rebuilding the Damaged Heart: Mesenchymal Stem Cells, Cell-Based Therapy, and Engineered Heart Tissue.

Physiol Rev 2016 07;96(3):1127-68

Interdisciplinary Stem Cell Institute, Department of Medicine, and Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1152/physrev.00019.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345247PMC
July 2016

Is the regulation of SIRT1 by miRNA-34a the key to mesenchymal stem cell survival?

Ann Transl Med 2016 Jun;4(12):243

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.21037/atm.2016.05.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930520PMC
June 2016

Antagonism of stem cell factor/c-kit signaling attenuates neonatal chronic hypoxia-induced pulmonary vascular remodeling.

Pediatr Res 2016 Apr 24;79(4):637-46. Epub 2015 Dec 24.

The Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1038/pr.2015.275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837030PMC
April 2016

Differentiation potential of individual olfactory c-Kit+ progenitors determined via multicolor lineage tracing.

Dev Neurobiol 2016 Mar 10;76(3):241-51. Epub 2015 Jun 10.

Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1002/dneu.22310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662645PMC
March 2016

Cell Therapy Augments Myocardial Perfusion and Improves Quality of Life in Patients With Refractory Angina.

Circ Res 2016 Mar;118(6):911-5

From The Interdisciplinary Stem Cell Institute (V.F., W.B., I.H.S., J.M.H.) and Department of Medicine (W.B., I.H.S., J.M.H.), University of Miami, Miller School of Medicine, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180594PMC
March 2016

Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease.

Stem Cells Transl Med 2016 Feb 18;5(2):186-91. Epub 2015 Dec 18.

Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, Florida, USA Department of Medicine, Miller School of Medicine, University of Miami, Miami, Florida, USA.

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http://dx.doi.org/10.5966/sctm.2015-0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729551PMC
February 2016

Murine Models Demonstrate Distinct Vasculogenic and Cardiomyogenic cKit+ Lineages in the Heart.

Circ Res 2016 Feb;118(3):382-7

From the Interdisciplinary Stem Cell Institute (K.E.H.), and Department of Medicine, Division of Cardiology and Department of Molecular and Cellular Pharmacology (J.M.H.), Leonard M. Miller School of Medicine, University of Miami, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.308061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746002PMC
February 2016

Sympathetic Reinnervation Is Required for Mammalian Cardiac Regeneration.

Circ Res 2015 Dec 14;117(12):990-4. Epub 2015 Sep 14.

From the Interdisciplinary Stem Cell Institute (I.A.W., W.B., J.M.H.) Departments of Medicine (W.B., J.M.H.) and Molecular and Cellular Pharmacology (J.M.H.), University of Miami Miller School of Medicine, FL; and Department of Genetics, University of Georgia, Athens (J.G.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705031PMC
December 2015

Perspectives on the Evolution of Stem Cell Therapy for Heart Failure.

EBioMedicine 2015 Dec 26;2(12):1838-9. Epub 2015 Nov 26.

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, United States.

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http://dx.doi.org/10.1016/j.ebiom.2015.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703738PMC
December 2015

Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection.

Circ Res 2015 Oct 3;117(10):846-57. Epub 2015 Sep 3.

From the Department of Biological Chemistry (H.S.C., C.I.M., R.N.C., J.E.V.E.), Division of Cardiology, Department of Medicine (V.V., P.P.R., D.A.K., J.E.V.E.), The Johns Hopkins NHLBI Proteomics Innovation Center on Heart Failure (H.S.C., V.V., D.A.K., J.E.V.E.), Department of Medicine, Mass Spectrometry and Proteomic Core Facility (R.N.C.), Johns Hopkins University School of Medicine, Baltimore, MD; Thermo Fisher Scientific, Rockford, IL (R.D.B., J.C.R.); Advanced Clinical Biosystems Research Institute, Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (V.V., E.L.C., J.E.V.E.); Department of Medicine, Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL (W.B., J.M.H.); Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada (C.I.M.); and Division of Cardiology, Medical University of Graz, Austria (P.P.R.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979977PMC
October 2015

S-nitrosylation and MSC-mediated body composition.

Oncotarget 2015 Oct;6(30):28517-8

Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, FL, USA.

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http://dx.doi.org/10.18632/oncotarget.5672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745665PMC
October 2015

cKit+ cardiac progenitors of neural crest origin.

Proc Natl Acad Sci U S A 2015 Oct 5;112(42):13051-6. Epub 2015 Oct 5.

Interdisciplinary Stem Cell Institute, Leonard M. Miller School of Medicine, Miami, FL 33136;

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http://dx.doi.org/10.1073/pnas.1517201112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620867PMC
October 2015

Cell Therapy: Targeting Endogenous Repair Versus Remuscularization.

Circ Res 2015 Sep;117(8):659-61

From the Department of Medicine, Division of Cardiology (J.M.H.), Department of Molecular and Cellular Pharmacology (J.M.H.), and Interdisciplinary Stem Cell Institute (K.E.H., J.M.H.), Leonard M. Miller School of Medicine, University of Miami, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705032PMC
September 2015

Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice.

Proc Natl Acad Sci U S A 2015 Jul 29;112(30):E4138-46. Epub 2015 Jun 29.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136;

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http://dx.doi.org/10.1073/pnas.1505819112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522794PMC
July 2015

S-Nitrosoglutathione Reductase Deficiency Enhances the Proliferative Expansion of Adult Heart Progenitors and Myocytes Post Myocardial Infarction.

J Am Heart Assoc 2015 Jul 15;4(7). Epub 2015 Jul 15.

Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.) Department of Medicine, University of Miami Miller School of Medicine, Miami, FL (W.B., J.M.H.) Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL (M.A.B., R.M.K.T., J.M.H.).

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http://dx.doi.org/10.1161/JAHA.115.001974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608081PMC
July 2015

Mesenchymal Stem Cells as a Biological Drug for Heart Disease: Where Are We With Cardiac Cell-Based Therapy?

Circ Res 2015 Jul;117(3):229-33

From the Interdisciplinary Stem Cell Institute (C.S., J.M.H.), Department of Medicine, Division of Cardiology (J.M.H.), and Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL (J.M.H.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.117.30630
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http://dx.doi.org/10.1161/CIRCRESAHA.117.306306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571454PMC
July 2015

Bone Marrow Mononuclear Cell Therapy and Granulocyte Colony-Stimulating Factor for Acute Myocardial Infarction: Is it Time to Reconsider?

J Am Coll Cardiol 2015 Jun;65(22):2383-7

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1016/j.jacc.2015.03.571DOI Listing
June 2015

Regulation of oxygen delivery to the body via hypoxic vasodilation.

Proc Natl Acad Sci U S A 2015 May 5;112(20):6254-5. Epub 2015 May 5.

Department of Medicine, Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136

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http://dx.doi.org/10.1073/pnas.1506523112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443334PMC
May 2015

Xanthine oxidase inhibitors in heart failure: where do we go from here?

Circulation 2015 May 14;131(20):1741-4. Epub 2015 Apr 14.

From Department of Medicine (L.T., J.M.H.) and Interdisciplinary Stem Cell Institute (J.M.H.), University of Miami Miller School of Medicine, FL; and Veterans Affairs Medical Center, Miami, FL (L.T.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.016379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438774PMC
May 2015

miR-30e targets IGF2-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice.

Cardiovasc Res 2015 Apr 12;106(1):131-42. Epub 2015 Feb 12.

Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, USA Department of Medicine, Division of Cardiology, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, USA Vascular Biology Institute, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, USA

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http://cardiovascres.oxfordjournals.org/content/cardiovascre
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http://cardiovascres.oxfordjournals.org/cgi/doi/10.1093/cvr/
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http://dx.doi.org/10.1093/cvr/cvv030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375408PMC
April 2015

Use of mesenchymal stem cells for therapy of cardiac disease.

Circ Res 2015 Apr;116(8):1413-30

From the University of Miami Miller School of Medicine, Interdisciplinary Stem Cell Institute, FL.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.116.30361
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http://dx.doi.org/10.1161/CIRCRESAHA.116.303614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429294PMC
April 2015

Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine with subacute ischemic cardiomyopathy.

J Am Heart Assoc 2015 Mar 31;4(4). Epub 2015 Mar 31.

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL (L.L.B., R.M.K.T., V.Y.S., S.G., V.K., A.W., B.W., C.P., W.B., J.R., D.V., M.R., J.M.H.) Department of Medicine, University of Miami Miller School of Medicine, Miami, FL (N.L.B., A.M., R.Z.C., W.S., A.V.S., J.M.H.) Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL (R.M.K.T., C.P., J.M.H.).

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http://dx.doi.org/10.1161/JAHA.114.001464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579962PMC
March 2015

Interaction between neuronal nitric oxide synthase signaling and temperature influences sarcoplasmic reticulum calcium leak: role of nitroso-redox balance.

Circ Res 2015 Jan 17;116(1):46-55. Epub 2014 Oct 17.

From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.305172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282621PMC
January 2015

Allogeneic cell therapy: a new paradigm in therapeutics.

Circ Res 2015 Jan;116(1):12-5

From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.114.30549
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.114.305495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411634PMC
January 2015

Effect of aging on human mesenchymal stem cell therapy in ischemic cardiomyopathy patients.

J Am Coll Cardiol 2015 Jan;65(2):125-32

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405121PMC
January 2015

Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells and promote their survival.

Proc Natl Acad Sci U S A 2014 Dec 17;111(48):17260-5. Epub 2014 Nov 17.

Interdisciplinary Stem Cell Institute, Departments of Molecular and Cellular Pharmacology,

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http://dx.doi.org/10.1073/pnas.1420375111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260571PMC
December 2014

Can endothelial progenitor cells treat patients with refractory angina?

Circ Res 2014 Nov;115(11):904-7

From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.

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http://dx.doi.org/10.1161/CIRCRESAHA.114.305284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284967PMC
November 2014

Joshua M. Hare: converging on cardiac regeneration.

Circ Res 2014 Oct;115(9):755-8

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http://dx.doi.org/10.1161/CIRCRESAHA.114.305255DOI Listing
October 2014