Publications by authors named "Joshua M Francis"

27Publications

Chromatin Looping Shapes KLF5-Dependent Transcriptional Programs in Human Epithelial Cancers.

Cancer Res 2020 Dec 28;80(24):5464-5477. Epub 2020 Oct 28.

Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.

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December 2020

Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets.

Cancer Biol Ther 2016 12 1;17(12):1274-1281. Epub 2016 Nov 1.

b Department of Medical Oncology & Center for Cancer Genome Discovery , Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA.

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December 2016

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

Nat Genet 2016 Feb 14;48(2):176-82. Epub 2015 Dec 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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February 2016

Chromothripsis from DNA damage in micronuclei.

Nature 2015 Jun 27;522(7555):179-84. Epub 2015 May 27.

1] Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA [3] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA [4] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA.

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June 2015

ARID1A and TERT promoter mutations in dedifferentiated meningioma.

Cancer Genet 2015 Jun 18;208(6):345-50. Epub 2015 Mar 18.

Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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June 2015

Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.

Mol Cancer Res 2015 Apr 23;13(4):689-98. Epub 2014 Dec 23.

Department of Medical Oncology, Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Cancer program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

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April 2015

EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.

Cancer Discov 2014 Aug 3;4(8):956-71. Epub 2014 Jun 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts. Department of Pathology, Boston Children's Hospital, Boston, Massachusetts. Department of Pathology, Harvard Medical School, Boston, Massachusetts.

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August 2014

Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization.

Cancer Res 2013 Nov 24;73(22):6770-9. Epub 2013 Sep 24.

Authors' Affiliations: Departments of Medical Oncology and Cancer Biology; Center for Cancer Genome Discovery, Lowe Center for Thoracic Oncology, and Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute; Departments of Medicine, Brigham and Women's Hospital; Departments of Biological Chemistry and Molecular Pharmacology and Pathology, Harvard Medical School, Boston, Massachusetts; Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea; and The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

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November 2013

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.

Proc Natl Acad Sci U S A 2009 Jan 9;106(3):755-60. Epub 2009 Jan 9.

Department of Medical Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA 02115, USA.

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January 2009