Joshua M Francis

Joshua M Francis

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Joshua M Francis

Joshua M Francis

Publications by authors named "Joshua M Francis"

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26Publications

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Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets.

Cancer Biol Ther 2016 12 1;17(12):1274-1281. Epub 2016 Nov 1.

b Department of Medical Oncology & Center for Cancer Genome Discovery , Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/15384047.2016.1250986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199165PMC
December 2016

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

Nat Genet 2016 Feb 14;48(2):176-82. Epub 2015 Dec 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857881PMC
February 2016

ARID1A and TERT promoter mutations in dedifferentiated meningioma.

Cancer Genet 2015 Jun 18;208(6):345-50. Epub 2015 Mar 18.

Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2015.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882906PMC
June 2015

Chromothripsis from DNA damage in micronuclei.

Nature 2015 Jun 27;522(7555):179-84. Epub 2015 May 27.

1] Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA [3] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA [4] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA.

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http://dx.doi.org/10.1038/nature14493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742237PMC
June 2015

Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.

Mol Cancer Res 2015 Apr 23;13(4):689-98. Epub 2014 Dec 23.

Department of Medical Oncology, Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Cancer program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0457DOI Listing
April 2015

EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.

Cancer Discov 2014 Aug 3;4(8):956-71. Epub 2014 Jun 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts. Department of Pathology, Boston Children's Hospital, Boston, Massachusetts. Department of Pathology, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125473PMC
August 2014

Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization.

Cancer Res 2013 Nov 24;73(22):6770-9. Epub 2013 Sep 24.

Authors' Affiliations: Departments of Medical Oncology and Cancer Biology; Center for Cancer Genome Discovery, Lowe Center for Thoracic Oncology, and Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute; Departments of Medicine, Brigham and Women's Hospital; Departments of Biological Chemistry and Molecular Pharmacology and Pathology, Harvard Medical School, Boston, Massachusetts; Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea; and The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903789PMC
November 2013

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.

Proc Natl Acad Sci U S A 2009 Jan 9;106(3):755-60. Epub 2009 Jan 9.

Department of Medical Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0812023106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615665PMC
January 2009