Publications by authors named "Joshua D Milner"

100Publications

The Child with Elevated IgE and Infection Susceptibility.

Curr Allergy Asthma Rep 2020 Aug 24;20(11):65. Epub 2020 Aug 24.

Division of Allergy, Immunology and Rheumatology, Columbia University Medical Center, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA.

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http://dx.doi.org/10.1007/s11882-020-00964-yDOI Listing
August 2020

Primary Atopic Disorders.

Authors:
Joshua D Milner

Annu Rev Immunol 2020 Apr 3;38:785-808. Epub 2020 Mar 3.

Department of Pediatrics, Columbia University Irving Medical Center, New York, NY 10032, USA; email:

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http://dx.doi.org/10.1146/annurev-immunol-042718-041553DOI Listing
April 2020

Usefulness of testing for hereditary alpha tryptasemia in symptomatic patients with elevated tryptase.

J Allergy Clin Immunol Pract 2020 Jun 23;8(6):2066-2067. Epub 2020 Jan 23.

Division of Clinical Immunology and Allergy, Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.01.012DOI Listing
June 2020

Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions.

J Clin Immunol 2020 01 9;40(1):227-231. Epub 2019 Nov 9.

Center of Excellence for Medical Genomics, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.

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http://dx.doi.org/10.1007/s10875-019-00693-6DOI Listing
January 2020

Measurement of serum tenascin-X in patients with congenital adrenal hyperplasia at risk for Ehlers-Danlos contiguous gene deletion syndrome CAH-X.

BMC Res Notes 2019 Oct 30;12(1):711. Epub 2019 Oct 30.

National Institutes of Health Clinical Center, 10 Center Drive, Building 10, Room 1-2740, Bethesda, MD, 20892-1932, USA.

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http://dx.doi.org/10.1186/s13104-019-4753-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820911PMC
October 2019

Editorial overview: Collusion between genes and environment in the pathogenesis of allergic disease.

Curr Opin Immunol 2019 10;60:iii-v

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Clinical Center Drive, Building 10, Room 11N240B, MSC 1889, Bethesda, MD 20892, United States. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2019.09.002DOI Listing
October 2019

Clinical response to omalizumab in patients with hereditary α-tryptasemia.

Ann Allergy Asthma Immunol 2020 01 9;124(1):99-100.e1. Epub 2019 Oct 9.

Laboratory of Allergic Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2019.09.026DOI Listing
January 2020

Gene-environment interactions in primary atopic disorders.

Curr Opin Immunol 2019 10 11;60:148-155. Epub 2019 Jul 11.

Laboratory of Allergic Diseases, NIAID, NIH, 9000 Rockville Pike, NIH Building 10 Room 11N240A, United States. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2019.06.002DOI Listing
October 2019

Novel MALT1 Mutation Linked to Immunodeficiency, Immune Dysregulation, and an Abnormal T Cell Receptor Repertoire.

J Clin Immunol 2019 05 29;39(4):401-413. Epub 2019 Apr 29.

Pediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, 52621, Tel Hashomer, Israel.

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http://link.springer.com/10.1007/s10875-019-00629-0
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http://dx.doi.org/10.1007/s10875-019-00629-0DOI Listing
May 2019

Editorial: Continued Fascination-A Tribute to a Giant in Immunology, Dr. William E. Paul.

Front Immunol 2019 8;10:354. Epub 2019 Mar 8.

Independent Researcher, Washington DC, United States.

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http://dx.doi.org/10.3389/fimmu.2019.00354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418019PMC
April 2020

The clinical and mechanistic intersection of primary atopic disorders and inborn errors of growth and metabolism.

Immunol Rev 2019 01;287(1):135-144

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1111/imr.12727DOI Listing
January 2019

Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources.

Nucleic Acids Res 2019 01;47(D1):D1018-D1027

Monarch Initiative, monarchinitiative.org.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky1105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324074PMC
January 2019

The overlap between allergy and immunodeficiency.

Curr Opin Pediatr 2018 12;30(6):848-854

Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, Maryland, USA.

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http://Insights.ovid.com/crossref?an=00008480-900000000-9893
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http://dx.doi.org/10.1097/MOP.0000000000000697DOI Listing
December 2018

Loss-of-function mutations in caspase recruitment domain-containing protein 14 (CARD14) are associated with a severe variant of atopic dermatitis.

J Allergy Clin Immunol 2019 01 21;143(1):173-181.e10. Epub 2018 Sep 21.

Department of Dermatology, Tel Aviv Medical Center, Tel Aviv, Israel; Department of Human Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183134
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http://dx.doi.org/10.1016/j.jaci.2018.09.002DOI Listing
January 2019

Human T9 differentiation is dependent on signal transducer and activator of transcription (STAT) 3 to restrain STAT1-mediated inhibition.

J Allergy Clin Immunol 2019 03 18;143(3):1108-1118.e4. Epub 2018 Jul 18.

Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.06.036DOI Listing
March 2019

Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression.

J Immunol 2018 07 13;201(2):757-771. Epub 2018 Jun 13.

Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.4049/jimmunol.1800158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069956PMC
July 2018

Aspergillosis, eosinophilic esophagitis, and allergic rhinitis in signal transducer and activator of transcription 3 haploinsufficiency.

J Allergy Clin Immunol 2018 09 24;142(3):993-997.e3. Epub 2018 May 24.

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.05.009DOI Listing
September 2018

First Identification of an Inherited TPSAB1 Quintuplication in a Patient with Clonal Mast Cell Disease.

J Clin Immunol 2018 05 11;38(4):457-459. Epub 2018 May 11.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11N240, MSC 1889, Bethesda, MD, 20892-1881, USA.

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http://dx.doi.org/10.1007/s10875-018-0506-yDOI Listing
May 2018

TCR Signaling Abnormalities in Human Th2-Associated Atopic Disease.

Authors:
Joshua D Milner

Front Immunol 2018 16;9:719. Epub 2018 Apr 16.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911486PMC
May 2019

Primary atopic disorders.

J Exp Med 2018 04 16;215(4):1009-1022. Epub 2018 Mar 16.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.1084/jem.20172306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881472PMC
April 2018

Learning from Job: A Rare Genetic Disease and Lessons of Biblical Proportions.

Authors:
Joshua D Milner

Rambam Maimonides Med J 2018 Jan 29;9(1). Epub 2018 Jan 29.

Chief, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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https://www.rmmj.org.il/issues/36/articles/814
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http://dx.doi.org/10.5041/RMMJ.10326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796737PMC
January 2018

Impact of food allergy on the growth of children with moderate-severe atopic dermatitis.

J Allergy Clin Immunol 2018 04 21;141(4):1526-1529.e4. Epub 2018 Feb 21.

Laboratory of Allergic Diseases, National Institutes of Allergy and Infectious Diseases, Bethesda, Md. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183011
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http://dx.doi.org/10.1016/j.jaci.2017.11.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889954PMC
April 2018

Persistent tryptase elevation in a patient with Gaucher disease.

J Allergy Clin Immunol Pract 2018 Mar - Apr;6(2):697-699. Epub 2017 Oct 13.

Division of Allergy & Immunology, Department of Pediatrics, Icahn School of Medicine, New York, NY.

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http://dx.doi.org/10.1016/j.jaip.2017.08.039DOI Listing
November 2019

A common haplotype containing functional CACNA1H variants is frequently coinherited with increased TPSAB1 copy number.

Genet Med 2018 04 21;20(5):503-512. Epub 2017 Sep 21.

Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://www.nature.com/doifinder/10.1038/gim.2017.136
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http://dx.doi.org/10.1038/gim.2017.136DOI Listing
April 2018

PD-L1 up-regulation restrains Th17 cell differentiation in loss- and gain-of-function patients.

J Exp Med 2017 Sep 14;214(9):2523-2533. Epub 2017 Jul 14.

Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD

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http://www.jem.org/lookup/doi/10.1084/jem.20161427
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http://dx.doi.org/10.1084/jem.20161427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584116PMC
September 2017

Low IgE Is Insufficiently Sensitive to Guide Genetic Testing of Gain-of-Function Mutations.

Clin Chem 2017 09 30;63(9):1539-1540. Epub 2017 Jun 30.

Adult Immunodeficiency Unit Infectious Diseases, Inflammation Center and Rare Diseases Center Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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http://dx.doi.org/10.1373/clinchem.2017.273458DOI Listing
September 2017

Up, Down, and All Around: Diagnosis and Treatment of Novel STAT3 Variant.

Front Pediatr 2017 13;5:49. Epub 2017 Mar 13.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) , Bethesda, MD , USA.

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http://dx.doi.org/10.3389/fped.2017.00049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347118PMC
March 2017

Detection of phosphoglucomutase-3 deficiency by lectin-based flow cytometry.

J Allergy Clin Immunol 2017 07 4;140(1):291-294.e4. Epub 2017 Jan 4.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.12.951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496781PMC
July 2017

Atopic Dermatitis and Allergic Urticaria: Cutaneous Manifestations of Immunodeficiency.

Immunol Allergy Clin North Am 2017 02 28;37(1):1-10. Epub 2016 Oct 28.

National Institute of Allergy and Infectious Diseases, Genetics and Pathogenesis of Allergy Section, 10 Center Drive, Building 10 Room 11N240A, Bethesda, MD 20814, USA. Electronic address:

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http://dx.doi.org/10.1016/j.iac.2016.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199140PMC
February 2017

Cool-temperature-mediated activation of phospholipase C-γ2 in the human hereditary disease PLAID.

Cell Signal 2016 09 17;28(9):1237-51. Epub 2016 May 17.

Institute of Pharmacology and Toxicology, Ulm University Medical Center, 89070 Ulm, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2016.05.010DOI Listing
September 2016

Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype.

Blood 2016 06 25;127(25):3154-64. Epub 2016 Apr 25.

Paris Descartes University, Sorbonne Paris Cité, Institut Imagine, Paris, France; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Necker Medical School, Paris, France; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY; Department of Infectious and Tropical Diseases, Necker-Enfants Malades Hospital, AP-HP, Paris, France.

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http://dx.doi.org/10.1182/blood-2015-11-679902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920021PMC
June 2016

Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis.

J Allergy Clin Immunol 2016 07 2;138(1):187-199. Epub 2016 Mar 2.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931983PMC
July 2016

Long-Acting Beta Agonists Enhance Allergic Airway Disease.

PLoS One 2015 25;10(11):e0142212. Epub 2015 Nov 25.

Departments of Medicine and Pathology & Immunology, Translational Biology and Molecular Medicine Program, and the Biology of Inflammation Center, Baylor College of Medicine and the Michael E. DeBakey VA Center for Translational Research on Inflammatory Diseases, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142212PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659681PMC
June 2016

Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function.

J Allergy Clin Immunol 2016 Mar 1;137(3):907-18.e9. Epub 2015 Oct 1.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.08.007DOI Listing
March 2016

TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition.

J Leukoc Biol 2016 Mar 22;99(3):505-13. Epub 2015 Sep 22.

Laboratories of *Molecular Biology and Immunology and Genetics, Gene Expression and Genomics and Bioinformatics Units, and Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA; and Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1189/jlb.6A0215-071RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338248PMC
March 2016

Genetics of allergy and allergic sensitization: common variants, rare mutations.

Curr Opin Immunol 2015 Oct 18;36:115-26. Epub 2015 Sep 18.

Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.coi.2015.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610744PMC
October 2015

GATA3 haploinsufficiency does not block allergic sensitization or atopic disease.

J Allergy Clin Immunol 2016 Feb 15;137(2):627-629.e2. Epub 2015 Aug 15.

Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.06.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747849PMC
February 2016

The Ying and Yang of STAT3 in Human Disease.

J Clin Immunol 2015 Oct 18;35(7):615-23. Epub 2015 Aug 18.

Department of Pediatrics, Division of Rheumatology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s10875-015-0187-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628878PMC
October 2015

Eosinophilia Associated with Disorders of Immune Deficiency or Immune Dysregulation.

Immunol Allergy Clin North Am 2015 Aug;35(3):523-44

Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Drive, Building 10/CRC, Room 12C103, Bethesda, MD 20892, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08898561150003
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http://dx.doi.org/10.1016/j.iac.2015.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688016PMC
August 2015

PLAID: a Syndrome of Complex Patterns of Disease and Unique Phenotypes.

Authors:
Joshua D Milner

J Clin Immunol 2015 Aug 25;35(6):527-30. Epub 2015 Jul 25.

Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, NIAID, NIH, 10 Center Drive, NIH Building 10-CRC 5-3950, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10875-015-0177-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575258PMC
August 2015

Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells.

Proc Natl Acad Sci U S A 2015 Jul 13;112(30):9394-9. Epub 2015 Jul 13.

Laboratory of Molecular Immunology and Immunology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1674;

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http://dx.doi.org/10.1073/pnas.1511711112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522759PMC
July 2015

Glycans Instructing Immunity: The Emerging Role of Altered Glycosylation in Clinical Immunology.

Front Pediatr 2015 11;3:54. Epub 2015 Jun 11.

Immunology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health , Bethesda, MD , USA ; Primary Immunodeficiency Clinic, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, MD , USA.

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http://dx.doi.org/10.3389/fped.2015.00054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463932PMC
June 2015

Atopic dermatitis in children: clinical features, pathophysiology, and treatment.

Immunol Allergy Clin North Am 2015 Feb 21;35(1):161-83. Epub 2014 Nov 21.

Genetics and Pathophysiology of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.iac.2014.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254569PMC
February 2015

Human IL-21 and IL-21R deficiencies: two novel entities of primary immunodeficiency.

Curr Opin Pediatr 2014 Dec;26(6):704-12

aDepartment of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig Maximilians University, Munich bInstitute of Immunology, Hannover Medical School, Hannover, Germany cLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://pdfs.journals.lww.com/co-pediatrics/2014/12000/Human_
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http://dx.doi.org/10.1097/MOP.0000000000000160DOI Listing
December 2014

The autoinhibitory C-terminal SH2 domain of phospholipase C-γ2 stabilizes B cell receptor signalosome assembly.

Sci Signal 2014 Sep 16;7(343):ra89. Epub 2014 Sep 16.

Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

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http://dx.doi.org/10.1126/scisignal.2005392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180509PMC
September 2014

Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development.

J Allergy Clin Immunol 2014 Apr 7;133(4):1109-15. Epub 2014 Jan 7.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972286PMC
April 2014

Pathogen-sensing, regulatory T cells, and responsiveness-tuning collectively regulate foreign- and self-antigen mediated T-cell responses.

Cold Spring Harb Symp Quant Biol 2013 7;78:265-76. Epub 2013 Oct 7.

Laboratory of Immunology and Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-1892.

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http://dx.doi.org/10.1101/sqb.2013.78.020198DOI Listing
March 2015

Elevated IgE and atopy in patients treated for early-onset ADA-SCID.

J Allergy Clin Immunol 2013 Dec 26;132(6):1444-6. Epub 2013 Jul 26.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.

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http://dx.doi.org/10.1016/j.jaci.2013.05.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844080PMC
December 2013

The cup runneth over: lessons from the ever-expanding pool of primary immunodeficiency diseases.

Nat Rev Immunol 2013 Sep 26;13(9):635-48. Epub 2013 Jul 26.

Allergic Inflammation Unit, Laboratory of Allergic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nri3493DOI Listing
September 2013

Peptide library-based evaluation of T-cell receptor breadth detects defects in global and regulatory activation in human immunologic diseases.

Proc Natl Acad Sci U S A 2013 May 1;110(20):8164-9. Epub 2013 May 1.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.1302103110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657790PMC
May 2013

Intermediate phenotypes in patients with autosomal dominant hyper-IgE syndrome caused by somatic mosaicism.

J Allergy Clin Immunol 2013 Jun 25;131(6):1586-93. Epub 2013 Apr 25.

Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md., USA.

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http://dx.doi.org/10.1016/j.jaci.2013.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103905PMC
June 2013

Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.

J Allergy Clin Immunol 2013 May;131(5):1276-87

Molecular Immunology and Inflammation Branch, National Institutes of Arthritis, and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892-1930, USA.

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http://dx.doi.org/10.1016/j.jaci.2013.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677748PMC
May 2013

HOIL and water: the two faces of HOIL-1 deficiency.

Nat Immunol 2012 Dec;13(12):1133-5

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http://dx.doi.org/10.1038/ni.2471DOI Listing
December 2012

IL-17 producing cells in host defense and atopy.

Authors:
Joshua D Milner

Curr Opin Immunol 2011 Dec 21;23(6):784-8. Epub 2011 Oct 21.

Laboratory of Allergic Diseases, National Institute for Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S095279151100144
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http://dx.doi.org/10.1016/j.coi.2011.09.006DOI Listing
December 2011

Altered T-cell receptor signaling in the pathogenesis of allergic disease.

J Allergy Clin Immunol 2011 Feb;127(2):351-4

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.jaci.2010.11.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050552PMC
February 2011

Highly variable clinical phenotypes of hypomorphic RAG1 mutations.

Pediatrics 2010 Nov 18;126(5):e1248-52. Epub 2010 Oct 18.

Duke University School of Medicine, Durham, North Carolina, USA.

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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
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http://dx.doi.org/10.1542/peds.2009-3171DOI Listing
November 2010

Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections.

Curr Opin HIV AIDS 2010 Mar;5(2):179-83

Allergic Inflammation Unit, Laboratory of Allergic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1097/COH.0b013e328335ed3eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485419PMC
March 2010