Josh Lauring

Josh Lauring

UNVERIFIED PROFILE

Are you Josh Lauring?   Register this Author

Register author
Josh Lauring

Josh Lauring

Publications by authors named "Josh Lauring"

Are you Josh Lauring?   Register this Author

39Publications

1187Reads

49Profile Views

Clinical Benefit to an Aurora A Kinase Inhibitor in a Patient with Metastatic Integrase Interactor 1-Deficient Carcinoma.

Oncologist 2019 02 8;24(2):146-150. Epub 2018 Oct 8.

Department of Oncology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2018-0279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369939PMC
February 2019

PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.

Breast Cancer Res Treat 2017 04 11;162(3):451-464. Epub 2017 Feb 11.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 1650 Orleans Street, Room 151, Baltimore, MD, 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-017-4147-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100768PMC
April 2017

Using cancer genomics to guide clinical decisions.

Cancer 2017 04 2;123(8):1288-1291. Epub 2017 Mar 2.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.30640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789460PMC
April 2017

A Polycythemia Vera JAK2 Mutation Masquerading as a Duodenal Cancer Mutation.

J Natl Compr Canc Netw 2016 12;14(12):1495-1498

From The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, and The Whiting School of Engineering, Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.6004/jnccn.2016.0161DOI Listing
December 2016

Evolving Role of the Estrogen Receptor as a Predictive Biomarker: ESR1 Mutational Status and Endocrine Resistance in Breast Cancer.

J Clin Oncol 2016 09 5;34(25):2950-2. Epub 2016 Jul 5.

The Johns Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2016.68.4720
Publisher Site
http://dx.doi.org/10.1200/JCO.2016.68.4720DOI Listing
September 2016

ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.

Clin Cancer Res 2016 Feb 10;22(4):993-9. Epub 2015 Aug 10.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland. The Whiting School of Engineering, Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-15-0943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993201PMC
February 2016

Recurrent AKT mutations in human cancers: functional consequences and effects on drug sensitivity.

Oncotarget 2016 Jan;7(4):4241-51

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/6648
Publisher Site
http://dx.doi.org/10.18632/oncotarget.6648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826202PMC
January 2016

HER2 missense mutations have distinct effects on oncogenic signaling and migration.

Proc Natl Acad Sci U S A 2015 Nov 27;112(45):E6205-14. Epub 2015 Oct 27.

Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1516853112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653184PMC
November 2015

Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA.

Clin Biochem 2015 Oct 31;48(15):993-8. Epub 2015 Jul 31.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; The Whiting School of Engineering, Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiochem.2015.07.097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600652PMC
October 2015

NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability.

Proc Natl Acad Sci U S A 2015 Sep 31;112(37):11583-8. Epub 2015 Aug 31.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287; Department of Chemical and Biomolecular Engineering, The Whiting School of Engineering, Johns Hopkins University, Baltimore, MD 21218

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1503683112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577188PMC
September 2015

Engineering targeted chromosomal amplifications in human breast epithelial cells.

Breast Cancer Res Treat 2015 Jul 23;152(2):313-21. Epub 2015 Jun 23.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University, CRB 1 Room 146, 1650 Orleans Street, Baltimore, MD, 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-015-3468-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491111PMC
July 2015

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.

Proc Natl Acad Sci U S A 2014 Dec 24;111(49):17606-11. Epub 2014 Nov 24.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287; and The Whiting School of Engineering, Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1408650111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267353PMC
December 2014

Human cell line model for cancer-associated KRAS noncoding SNP.

Authors:
Josh Lauring

Hum Mutat 2014 Feb;35(2)

The Johns Hopkins University, Baltimore, MD.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/humu.22404
Publisher Site
http://dx.doi.org/10.1002/humu.22404DOI Listing
February 2014

PIK3CA and AKT1 mutations have distinct effects on sensitivity to targeted pathway inhibitors in an isogenic luminal breast cancer model system.

Clin Cancer Res 2013 Oct 25;19(19):5413-22. Epub 2013 Jul 25.

Authors' Affiliation: The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-0884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805128PMC
October 2013

The phosphoinositide-3-kinase-Akt-mTOR pathway as a therapeutic target in breast cancer.

J Natl Compr Canc Netw 2013 Jun;11(6):670-8

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21287, USA.

View Article

Download full-text PDF

Source
http://www.jnccn.org/content/11/6/670.full.pdf
Web Search
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086482PMC
http://dx.doi.org/10.6004/jnccn.2013.0086DOI Listing
June 2013

Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine.

Oncotarget 2013 Jan;4(1):29-34

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702205PMC
http://dx.doi.org/10.18632/oncotarget.755DOI Listing
January 2013

TORn in Two Over Breast Cancer Drug Resistance.

Oncology (Williston Park) 2013 Jan;27(1)

View Article

Download full-text PDF

Source
January 2013

BEAMing sheds light on drug resistance.

Clin Cancer Res 2011 Dec 7;17(24):7508-10. Epub 2011 Nov 7.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-11-2556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243814PMC
December 2011

A PCR-based high-throughput screen with multiround sample pooling: application to somatic cell gene targeting.

Nat Protoc 2007 ;2(11):2865-74

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, Maryland 21231, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nprot.2007.409
Publisher Site
http://dx.doi.org/10.1038/nprot.2007.409DOI Listing
February 2008

The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.

Blood 2008 Jan 17;111(2):856-64. Epub 2007 Oct 17.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Department of Chemical and Biomolecular Engineering, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2007-05-088674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200833PMC
January 2008

Tamoxifen-stimulated growth of breast cancer due to p21 loss.

Proc Natl Acad Sci U S A 2008 Jan 27;105(1):288-93. Epub 2007 Dec 27.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0710887105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224203PMC
January 2008

Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation.

Cancer Res 2007 Sep;67(18):8460-7

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-07-0108DOI Listing
September 2007

A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.

Immunity 2003 Jul;19(1):105-17

Division of Immunology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1074-7613(03)00181-xDOI Listing
July 2003