Josephine M Egan

Josephine M Egan

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Josephine M Egan

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Incretins in obesity and diabetes.

Ann N Y Acad Sci 2019 Aug 7. Epub 2019 Aug 7.

Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1111/nyas.14211DOI Listing
August 2019

Dietary curcumin enhances insulin clearance in diet-induced obese mice via regulation of hepatic PI3K-AKT axis and IDE, and preservation of islet integrity.

Nutr Metab (Lond) 2019 25;16:48. Epub 2019 Jul 25.

Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd, Suite 100, Baltimore, MD 21224 USA.

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http://dx.doi.org/10.1186/s12986-019-0377-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659288PMC
July 2019

Oral glucose load and mixed meal feeding lowers testosterone levels in healthy eugonadal men.

Endocrine 2019 01 6;63(1):149-156. Epub 2018 Sep 6.

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s12020-018-1741-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445266PMC
January 2019

Regular low-calorie sweetener consumption is associated with increased secretion of glucose-dependent insulinotropic polypeptide.

Diabetes Obes Metab 2018 09 9;20(9):2282-2285. Epub 2018 May 9.

Intramural Research Programme, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://doi.wiley.com/10.1111/dom.13328
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http://dx.doi.org/10.1111/dom.13328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105420PMC
September 2018

Insulin Is Transcribed and Translated in Mammalian Taste Bud Cells.

Endocrinology 2018 09;159(9):3331-3339

Laboratory of Clinical Investigation/Diabetes Section, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1210/en.2018-00534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112595PMC
September 2018

Age-Related Changes in Glucose Metabolism, Hyperglycemia, and Cardiovascular Risk.

Circ Res 2018 Sep;123(7):886-904

From the Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31280
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http://dx.doi.org/10.1161/CIRCRESAHA.118.312806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205735PMC
September 2018

Endocannabinoids in the Islets of Langerhans: the ugly, the bad, and the good facts.

Am J Physiol Endocrinol Metab 2018 08 6;315(2):E174-E179. Epub 2018 Apr 6.

Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health , Baltimore, Maryland.

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http://dx.doi.org/10.1152/ajpendo.00338.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139496PMC
August 2018

The physiology of endocrine systems with ageing.

Lancet Diabetes Endocrinol 2018 08 17;6(8):647-658. Epub 2018 Jul 17.

Department of Internal Medicine, Division of Endocrinology, Erasmus Medical Centre, Rotterdam, Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S22138587183002
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http://dx.doi.org/10.1016/S2213-8587(18)30026-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089223PMC
August 2018

Measurement of fat fraction in the human thymus by localized NMR and three-point Dixon MRI techniques.

Magn Reson Imaging 2018 07 29;50:110-118. Epub 2018 Mar 29.

Intramural Research Program, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.mri.2018.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971004PMC
July 2018

Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells.

J Cell Mol Med 2018 Apr 12;22(4):2337-2345. Epub 2018 Feb 12.

Department of Molecular Science and Technology, Ajou University, Suwon, South Korea.

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http://dx.doi.org/10.1111/jcmm.13523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867156PMC
April 2018

Evidence for brain glucose dysregulation in Alzheimer's disease.

Alzheimers Dement 2018 03 19;14(3):318-329. Epub 2017 Oct 19.

Clinical and Translational Neuroscience Unit, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866736PMC
March 2018

Targeted proteomics of cannabinoid receptor CB1 and the CB1b isoform.

J Pharm Biomed Anal 2017 Sep 11;144:154-158. Epub 2016 Nov 11.

Biomedical Research Center, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD 21224, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426998PMC
September 2017

Incretin secretion in humans is under the influence of cannabinoid receptors.

Am J Physiol Endocrinol Metab 2017 09 27;313(3):E359-E366. Epub 2017 Jun 27.

Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1152/ajpendo.00080.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625085PMC
September 2017

CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ-Tetrahydrocannabinol (Δ-THC)-Induced Aversive Effects in Mice.

Sci Rep 2017 09 26;7(1):12315. Epub 2017 Sep 26.

Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1038/s41598-017-12399-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614984PMC
September 2017

Chronic Low-Calorie Sweetener Use and Risk of Abdominal Obesity among Older Adults: A Cohort Study.

PLoS One 2016 23;11(11):e0167241. Epub 2016 Nov 23.

Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167241PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120853PMC
June 2017

Effects of transdermal testosterone gel or an aromatase inhibitor on serum concentration and pulsatility of growth hormone in older men with age-related low testosterone.

Metabolism 2017 Apr 19;69:143-147. Epub 2017 Jan 19.

Section on Men's Health, Aging and Metabolism, Brigham and Women's Hospital Harvard Medical School, Boston, MA, United States, 02115. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2017.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950718PMC
April 2017

Does GLP-1 suppress its own basal secretion?

Endocr Res 2016 17;41(1):16-20. Epub 2015 Jul 17.

b Diabetes Section, National Institute on Aging , Baltimore , MD , USA .

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http://dx.doi.org/10.3109/07435800.2015.1038353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168718PMC
December 2016

Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells.

PLoS One 2016 11;11(3):e0150981. Epub 2016 Mar 11.

Department of Molecular Science and Technology, Ajou University, Suwon, 16499, South Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0150981PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788443PMC
December 2016

Bioavailable Testosterone Linearly Declines Over A Wide Age Spectrum in Men and Women From The Baltimore Longitudinal Study of Aging.

J Gerontol A Biol Sci Med Sci 2016 09 27;71(9):1202-9. Epub 2016 Feb 27.

Translational Gerontology Branch, Longitudinal Study Section, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glw021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978359PMC
September 2016

Free Thyroxine and Functional Mobility, Fitness, and Fatigue in Euthyroid Older Men and Women in the Baltimore Longitudinal Study of Aging.

J Gerontol A Biol Sci Med Sci 2016 07 20;71(7):961-7. Epub 2016 Jan 20.

Intramural Research Program, National Institute on Aging, Baltimore, Maryland. Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glv226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906324PMC
July 2016

Association of abdominal fat with serum amylase in an older cohort: The Baltimore Longitudinal Study of Aging.

Diabetes Res Clin Pract 2016 Jun 26;116:212-7. Epub 2016 Apr 26.

Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21225, United States.

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http://dx.doi.org/10.1016/j.diabres.2016.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832961PMC
June 2016

Effects of Transdermal Testosterone Gel or an Aromatase Inhibitor on Prostate Volume in Older Men.

J Clin Endocrinol Metab 2016 04 7;101(4):1865-71. Epub 2016 Mar 7.

Laboratory of Clinical Investigation (J.P.D., D.M., J.M.E.) and Translational Gerontology Branch (M.S., L.F., C.W.C.), National Institute on Aging, and Imaging Section (M.G.), Medstar Harbor Hospital, Baltimore, Maryland 21225; and Section on Men's Health, Aging, and Metabolism (S.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-1111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880169PMC
April 2016

Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice.

Mol Cell Endocrinol 2016 Mar 25;423:1-10. Epub 2015 Dec 25.

National Institute on Aging/NIH, 251 Bayview Boulevard, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.mce.2015.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752920PMC
March 2016

Targeting Stem Cells in Chronic Myeloid Leukemia with a PPAR-γ Agonist.

Authors:
Josephine M Egan

N Engl J Med 2015 Nov;373(20):1973-5

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http://dx.doi.org/10.1056/NEJMcibr1511276DOI Listing
November 2015

Mechanisms of type 2 diabetes resolution after Roux-en-Y gastric bypass.

Surg Obes Relat Dis 2014 Nov-Dec;10(6):1028-39. Epub 2014 Aug 15.

Department of Surgery, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.soard.2014.07.011DOI Listing
August 2015

The endocrinology of taste receptors.

Nat Rev Endocrinol 2015 Apr 24;11(4):213-27. Epub 2015 Feb 24.

Laboratory of Clinical Investigation, National Institute on Aging, NIH, Biomedical Research Center, Room 09B133, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224-6825, USA.

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http://dx.doi.org/10.1038/nrendo.2015.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220401PMC
April 2015

Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds.

Cancer Med 2015 Feb 30;4(2):245-52. Epub 2014 Oct 30.

Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1002/cam4.350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329008PMC
February 2015

Prognostic classification of mild cognitive impairment and Alzheimer's disease: MRI independent component analysis.

Psychiatry Res 2014 Nov 17;224(2):81-8. Epub 2014 Aug 17.

Laboratory of Neurosciences, National Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2014.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586157PMC
November 2014

Resveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity.

J Endocrinol 2014 Nov;223(2):107-17

Laboratory of Clinical InvestigationLaboratory of Cardiovascular ScienceNational Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd, Baltimore, Maryland 21224, USA

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http://dx.doi.org/10.1530/JOE-14-0335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191183PMC
November 2014

Denatonium induces secretion of glucagon-like peptide-1 through activation of bitter taste receptor pathways.

Diabetologia 2014 Oct 13;57(10):2117-25. Epub 2014 Jul 13.

Department of Biochemistry, College of Korean Medicine, Kyung Hee University, Hoegi-Dong, Dongdaemun-Gu, Seoul, 130-701, Republic of Korea.

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http://dx.doi.org/10.1007/s00125-014-3326-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5160131PMC
October 2014

GLP-1(32-36)amide, a novel pentapeptide cleavage product of GLP-1, modulates whole body glucose metabolism in dogs.

Peptides 2014 Sep 14;59:20-4. Epub 2014 Jun 14.

Cardiovascular Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.peptides.2014.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155305PMC
September 2014

Pancreatic polypeptide inhibits somatostatin secretion.

FEBS Lett 2014 Aug 11;588(17):3233-9. Epub 2014 Jul 11.

Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2014.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143909PMC
August 2014

GIP contributes to islet trihormonal abnormalities in type 2 diabetes.

J Clin Endocrinol Metab 2014 Jul 8;99(7):2477-85. Epub 2014 Apr 8.

Laboratory of Clinical Investigation (C.W.C., J.O.O., O.D.C., J.M.E.) and Translational Gerontology Branch (L.F.), National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225; and Department of Molecular Science and Technology (W.K.), Ajou University, Suwon 443-749, South Korea.

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http://dx.doi.org/10.1210/jc.2013-3994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079310PMC
July 2014

The glucoregulatory benefits of glucagon-like peptide-1 (7-36) amide infusion during intensive insulin therapy in critically ill surgical patients: a pilot study.

Crit Care Med 2014 Mar;42(3):638-45

1Department of Medicine, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD. 2Department of Surgery, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD. 3Clinical Physiology Branch, National Institute on Aging, Baltimore, MD. 4Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.

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https://insights.ovid.com/crossref?an=00003246-201403000-000
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http://dx.doi.org/10.1097/CCM.0000000000000035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794001PMC
March 2014

Interleukin-6 is linked to longitudinal rates of cortical thinning in aging.

Transl Neurosci 2014 Mar;5(1):1-7

Laboratory of Behavioral Neuroscience, National Institute on Aging, NIH, Baltimore, MD, 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824945PMC
March 2014

Identification of CB1/CB2 ligands from Zanthoxylum bungeanum.

J Nat Prod 2013 Nov 31;76(11):2060-4. Epub 2013 Oct 31.

Biomedical Research Center, National Institute on Aging, National Institutes of Health , 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, United States.

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http://dx.doi.org/10.1021/np400478cDOI Listing
November 2013

Hormonal response to a mixed-meal challenge after reversal of gastric bypass for hypoglycemia.

J Clin Endocrinol Metab 2013 Jul 10;98(7):E1208-12. Epub 2013 May 10.

Division of Endocrinology and Metabolism, The Johns Hopkins University, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1210/jc.2013-1151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393460PMC
July 2013

Diabetes and altered glucose metabolism with aging.

Endocrinol Metab Clin North Am 2013 Jun 22;42(2):333-47. Epub 2013 Mar 22.

Division of Endocrinology and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.ecl.2013.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664017PMC
June 2013

Pancreas++: automated quantification of pancreatic islet cells in microscopy images.

Front Physiol 2012 3;3:482. Epub 2013 Jan 3.

Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health Baltimore, MD, USA.

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http://dx.doi.org/10.3389/fphys.2012.00482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535421PMC
January 2013

Perinatal exercise improves glucose homeostasis in adult offspring.

Am J Physiol Endocrinol Metab 2012 Oct 28;303(8):E1061-8. Epub 2012 Aug 28.

Graduate Center for Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, Kentucky 40536-0200, USA.

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http://dx.doi.org/10.1152/ajpendo.00213.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469606PMC
October 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R König Kay-Tee Khaw Lee M Kaplan Åsa Johansson A Cecile J W Janssens Wilmar Igl G Kees Hovingh Christian Hengstenberg Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Leif C Groop Elena Gonzalez Nelson B Freimer Jeanette Erdmann Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Ulf de Faire Gabriel Crawford Yii-der I Chen Mark J Caulfield S Matthijs Boekholdt Themistocles L Assimes Thomas Quertermous Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Herman A Taylor Stacey B Gabriel Hilma Holm Vilmundur Gudnason Ronald M Krauss Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt David P Strachan Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Sekar Kathiresan

PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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September 2012

A genome-wide association search for type 2 diabetes genes in African Americans.

Authors:
Nicholette D Palmer Caitrin W McDonough Pamela J Hicks Bong H Roh Maria R Wing S Sandy An Jessica M Hester Jessica N Cooke Meredith A Bostrom Megan E Rudock Matthew E Talbert Joshua P Lewis Assiamira Ferrara Lingyi Lu Julie T Ziegler Michele M Sale Jasmin Divers Daniel Shriner Adebowale Adeyemo Charles N Rotimi Maggie C Y Ng Carl D Langefeld Barry I Freedman Donald W Bowden Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Andrew P Morris Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Claudia Langenberg Oliver M Hofmann Josée Dupuis Lu Qi Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis David J Couper Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Norman Klopp Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne John R B Perry Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Karen L Mohlke Andrew D Morris Colin N A Palmer Peter P Pramstaller Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Nicholas J Wareham Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Frank B Hu James B Meigs James S Pankow Oluf Pedersen H-Erich Wichmann Inês Barroso Jose C Florez Timothy M Frayling Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Toby Johnson Paul Elliott Denis Rybin Peter Henneman Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Josephine M Egan Taina Lajunen Alex Doney Stavroula Kanoni Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Rune Frants Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg Andrew A Hicks David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Antti Jula Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino Alisa K Manning María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Ben A Oostra Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Markus Perola Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Bruce M Psaty Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Toshiko Tanaka Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Ruth J F Loos Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Veikko Salomaa George Davey Smith Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper George V Dedoussis Manuel Serrano-Ríos Lars Lind Lyle J Palmer Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter David S Siscovick Brenda W J H Penninx Dorret I Boomsma Panos Deloukas Timothy D Spector Luigi Ferrucci Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Dawn M Waterworth Peter Vollenweider Leena Peltonen Vincent Mooser Robert Sladek

PLoS One 2012 4;7(1):e29202. Epub 2012 Jan 4.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251563PMC
May 2012

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

Authors:
Alisa K Manning Marie-France Hivert Robert A Scott Jonna L Grimsby Nabila Bouatia-Naji Han Chen Denis Rybin Ching-Ti Liu Lawrence F Bielak Inga Prokopenko Najaf Amin Daniel Barnes Gemma Cadby Jouke-Jan Hottenga Erik Ingelsson Anne U Jackson Toby Johnson Stavroula Kanoni Claes Ladenvall Vasiliki Lagou Jari Lahti Cecile Lecoeur Yongmei Liu Maria Teresa Martinez-Larrad May E Montasser Pau Navarro John R B Perry Laura J Rasmussen-Torvik Perttu Salo Naveed Sattar Dmitry Shungin Rona J Strawbridge Toshiko Tanaka Cornelia M van Duijn Ping An Mariza de Andrade Jeanette S Andrews Thor Aspelund Mustafa Atalay Yurii Aulchenko Beverley Balkau Stefania Bandinelli Jacques S Beckmann John P Beilby Claire Bellis Richard N Bergman John Blangero Mladen Boban Michael Boehnke Eric Boerwinkle Lori L Bonnycastle Dorret I Boomsma Ingrid B Borecki Yvonne Böttcher Claude Bouchard Eric Brunner Danijela Budimir Harry Campbell Olga Carlson Peter S Chines Robert Clarke Francis S Collins Arturo Corbatón-Anchuelo David Couper Ulf de Faire George V Dedoussis Panos Deloukas Maria Dimitriou Josephine M Egan Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Elodie Eury Luigi Ferrucci Ian Ford Nita G Forouhi Caroline S Fox Maria Grazia Franzosi Paul W Franks Timothy M Frayling Philippe Froguel Pilar Galan Eco de Geus Bruna Gigante Nicole L Glazer Anuj Goel Leif Groop Vilmundur Gudnason Göran Hallmans Anders Hamsten Ola Hansson Tamara B Harris Caroline Hayward Simon Heath Serge Hercberg Andrew A Hicks Aroon Hingorani Albert Hofman Jennie Hui Joseph Hung Marjo-Riitta Jarvelin Min A Jhun Paul C D Johnson J Wouter Jukema Antti Jula W H Kao Jaakko Kaprio Sharon L R Kardia Sirkka Keinanen-Kiukaanniemi Mika Kivimaki Ivana Kolcic Peter Kovacs Meena Kumari Johanna Kuusisto Kirsten Ohm Kyvik Markku Laakso Timo Lakka Lars Lannfelt G Mark Lathrop Lenore J Launer Karin Leander Guo Li Lars Lind Jaana Lindstrom Stéphane Lobbens Ruth J F Loos Jian'an Luan Valeriya Lyssenko Reedik Mägi Patrik K E Magnusson Michael Marmot Pierre Meneton Karen L Mohlke Vincent Mooser Mario A Morken Iva Miljkovic Narisu Narisu Jeff O'Connell Ken K Ong Ben A Oostra Lyle J Palmer Aarno Palotie James S Pankow John F Peden Nancy L Pedersen Marina Pehlic Leena Peltonen Brenda Penninx Marijana Pericic Markus Perola Louis Perusse Patricia A Peyser Ozren Polasek Peter P Pramstaller Michael A Province Katri Räikkönen Rainer Rauramaa Emil Rehnberg Ken Rice Jerome I Rotter Igor Rudan Aimo Ruokonen Timo Saaristo Maria Sabater-Lleal Veikko Salomaa David B Savage Richa Saxena Peter Schwarz Udo Seedorf Bengt Sennblad Manuel Serrano-Rios Alan R Shuldiner Eric J G Sijbrands David S Siscovick Johannes H Smit Kerrin S Small Nicholas L Smith Albert Vernon Smith Alena Stančáková Kathleen Stirrups Michael Stumvoll Yan V Sun Amy J Swift Anke Tönjes Jaakko Tuomilehto Stella Trompet Andre G Uitterlinden Matti Uusitupa Max Vikström Veronique Vitart Marie-Claude Vohl Benjamin F Voight Peter Vollenweider Gerard Waeber Dawn M Waterworth Hugh Watkins Eleanor Wheeler Elisabeth Widen Sarah H Wild Sara M Willems Gonneke Willemsen James F Wilson Jacqueline C M Witteman Alan F Wright Hanieh Yaghootkar Diana Zelenika Tatijana Zemunik Lina Zgaga Nicholas J Wareham Mark I McCarthy Ines Barroso Richard M Watanabe Jose C Florez Josée Dupuis James B Meigs Claudia Langenberg

Nat Genet 2012 May 13;44(6):659-69. Epub 2012 May 13.

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.

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May 2012

Age-related changes in mouse taste bud morphology, hormone expression, and taste responsivity.

J Gerontol A Biol Sci Med Sci 2012 Apr 4;67(4):336-44. Epub 2011 Nov 4.

Laboratory of Clinical Investigation, Diabetes Section, National Institute on Aging, Baltimore, MD 21224, USA.

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April 2012

Relationship of serum fibroblast growth factor 21 with abnormal glucose metabolism and insulin resistance: the Baltimore Longitudinal Study of Aging.

J Clin Endocrinol Metab 2012 Apr 16;97(4):1375-82. Epub 2012 Feb 16.

Department of Opthalmology, Johns Hopkins School of Medicine, Smith Building, 400 North Broadway, M015, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1210/jc.2011-2823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319186PMC
April 2012

Selective contribution of regional adiposity, skeletal muscle, and adipokines to glucose disposal in older adults.

J Am Geriatr Soc 2012 Apr 14;60(4):707-12. Epub 2012 Mar 14.

Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA.

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April 2012

RNA-binding protein HuD controls insulin translation.

Mol Cell 2012 Mar 1;45(6):826-35. Epub 2012 Mar 1.

Laboratory of Molecular Biology and Immunology, National Institute on Aging-Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.molcel.2012.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319250PMC
March 2012

Cannabinoids induce pancreatic β-cell death by directly inhibiting insulin receptor activation.

Sci Signal 2012 Mar 20;5(216):ra23. Epub 2012 Mar 20.

National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524575PMC
March 2012

To be or not to be--obese.

Endocrinology 2011 Oct;152(10):3592-6

Intramural Research Program/National Institute on Aging/National Institutes of Health, Baltimore, Maryland 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176656PMC
October 2011

Cross-sectional evidence of a signaling pathway from bone homeostasis to glucose metabolism.

J Clin Endocrinol Metab 2011 Jun 9;96(6):E884-90. Epub 2011 Mar 9.

National Institute on Aging, Clinical Research Branch, 3001 South Hanover Street, Baltimore, Maryland 21225, USA.

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http://dx.doi.org/10.1210/jc.2010-2589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100745PMC
June 2011

Hyperinsulinemic hypoglycemia after Roux-en-Y gastric bypass: unraveling the role of gut hormonal and pancreatic endocrine dysfunction.

J Surg Res 2011 May 29;167(2):199-205. Epub 2010 Oct 29.

Department of Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148142PMC
May 2011

Roles of hormones in taste signaling.

Results Probl Cell Differ 2010 ;52:115-37

Diabetes Section/NIA/NIH, 251 Bayview Blvd, Baltimore, MD 21224, USA.

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February 2011

Insulin and glucagon regulate pancreatic α-cell proliferation.

PLoS One 2011 Jan 25;6(1):e16096. Epub 2011 Jan 25.

National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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January 2011

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.

Authors:
Nicole Soranzo Serena Sanna Eleanor Wheeler Christian Gieger Dörte Radke Josée Dupuis Nabila Bouatia-Naji Claudia Langenberg Inga Prokopenko Elliot Stolerman Manjinder S Sandhu Matthew M Heeney Joseph M Devaney Muredach P Reilly Sally L Ricketts Alexandre F R Stewart Benjamin F Voight Christina Willenborg Benjamin Wright David Altshuler Dan Arking Beverley Balkau Daniel Barnes Eric Boerwinkle Bernhard Böhm Amélie Bonnefond Lori L Bonnycastle Dorret I Boomsma Stefan R Bornstein Yvonne Böttcher Suzannah Bumpstead Mary Susan Burnett-Miller Harry Campbell Antonio Cao John Chambers Robert Clark Francis S Collins Josef Coresh Eco J C de Geus Mariano Dei Panos Deloukas Angela Döring Josephine M Egan Roberto Elosua Luigi Ferrucci Nita Forouhi Caroline S Fox Christopher Franklin Maria Grazia Franzosi Sophie Gallina Anuj Goel Jürgen Graessler Harald Grallert Andreas Greinacher David Hadley Alistair Hall Anders Hamsten Caroline Hayward Simon Heath Christian Herder Georg Homuth Jouke-Jan Hottenga Rachel Hunter-Merrill Thomas Illig Anne U Jackson Antti Jula Marcus Kleber Christopher W Knouff Augustine Kong Jaspal Kooner Anna Köttgen Peter Kovacs Knut Krohn Brigitte Kühnel Johanna Kuusisto Markku Laakso Mark Lathrop Cécile Lecoeur Man Li Mingyao Li Ruth J F Loos Jian'an Luan Valeriya Lyssenko Reedik Mägi Patrik K E Magnusson Anders Mälarstig Massimo Mangino María Teresa Martínez-Larrad Winfried März Wendy L McArdle Ruth McPherson Christa Meisinger Thomas Meitinger Olle Melander Karen L Mohlke Vincent E Mooser Mario A Morken Narisu Narisu David M Nathan Matthias Nauck Chris O'Donnell Konrad Oexle Nazario Olla James S Pankow Felicity Payne John F Peden Nancy L Pedersen Leena Peltonen Markus Perola Ozren Polasek Eleonora Porcu Daniel J Rader Wolfgang Rathmann Samuli Ripatti Ghislain Rocheleau Michael Roden Igor Rudan Veikko Salomaa Richa Saxena David Schlessinger Heribert Schunkert Peter Schwarz Udo Seedorf Elizabeth Selvin Manuel Serrano-Ríos Peter Shrader Angela Silveira David Siscovick Kjioung Song Timothy D Spector Kari Stefansson Valgerdur Steinthorsdottir David P Strachan Rona Strawbridge Michael Stumvoll Ida Surakka Amy J Swift Toshiko Tanaka Alexander Teumer Gudmar Thorleifsson Unnur Thorsteinsdottir Anke Tönjes Gianluca Usala Veronique Vitart Henry Völzke Henri Wallaschofski Dawn M Waterworth Hugh Watkins H-Erich Wichmann Sarah H Wild Gonneke Willemsen Gordon H Williams James F Wilson Juliane Winkelmann Alan F Wright Carina Zabena Jing Hua Zhao Stephen E Epstein Jeanette Erdmann Hakon H Hakonarson Sekar Kathiresan Kay-Tee Khaw Robert Roberts Nilesh J Samani Mark D Fleming Robert Sladek Gonçalo Abecasis Michael Boehnke Philippe Froguel Leif Groop Mark I McCarthy W H Linda Kao Jose C Florez Manuela Uda Nicholas J Wareham Inês Barroso James B Meigs

Diabetes 2010 Dec 21;59(12):3229-39. Epub 2010 Sep 21.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.

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December 2010

Glucagon signaling modulates sweet taste responsiveness.

FASEB J 2010 Oct 14;24(10):3960-9. Epub 2010 Jun 14.

Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 S. Penn St., Rm. S251, Baltimore, MD 21201, USA.

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October 2010

Influence of leptin, adiponectin, and resistin on the association between abdominal adiposity and arterial stiffness.

Am J Hypertens 2010 May 11;23(5):501-7. Epub 2010 Feb 11.

Department of Internal Medicine, Division of Geriatric Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.

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May 2010

Is longitudinal pulse pressure a better predictor of 24-hour urinary albumin excretion than other indices of blood pressure?

Hypertension 2010 Feb 14;55(2):415-21. Epub 2009 Dec 14.

MedStar Research Institute, National Institute on Aging, National Institutes of Health, Baltimore, Md, USA.

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February 2010

Notch signaling in pancreatic endocrine cell and diabetes.

Biochem Biophys Res Commun 2010 Feb 24;392(3):247-51. Epub 2009 Dec 24.

NIA/NIH, Baltimore, MD 21224, USA.

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February 2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

Authors:
Richa Saxena Marie-France Hivert Claudia Langenberg Toshiko Tanaka James S Pankow Peter Vollenweider Valeriya Lyssenko Nabila Bouatia-Naji Josée Dupuis Anne U Jackson W H Linda Kao Man Li Nicole L Glazer Alisa K Manning Jian'an Luan Heather M Stringham Inga Prokopenko Toby Johnson Niels Grarup Trine W Boesgaard Cécile Lecoeur Peter Shrader Jeffrey O'Connell Erik Ingelsson David J Couper Kenneth Rice Kijoung Song Camilla H Andreasen Christian Dina Anna Köttgen Olivier Le Bacquer François Pattou Jalal Taneera Valgerdur Steinthorsdottir Denis Rybin Kristin Ardlie Michael Sampson Lu Qi Mandy van Hoek Michael N Weedon Yurii S Aulchenko Benjamin F Voight Harald Grallert Beverley Balkau Richard N Bergman Suzette J Bielinski Amelie Bonnefond Lori L Bonnycastle Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Thomas A Buchanan Suzannah J Bumpstead Christine Cavalcanti-Proença Guillaume Charpentier Yii-Der Ida Chen Peter S Chines Francis S Collins Marilyn Cornelis Gabriel J Crawford Jerome Delplanque Alex Doney Josephine M Egan Michael R Erdos Mathieu Firmann Nita G Forouhi Caroline S Fox Mark O Goodarzi Jürgen Graessler Aroon Hingorani Bo Isomaa Torben Jørgensen Mika Kivimaki Peter Kovacs Knut Krohn Meena Kumari Torsten Lauritzen Claire Lévy-Marchal Vladimir Mayor Jarred B McAteer David Meyre Braxton D Mitchell Karen L Mohlke Mario A Morken Narisu Narisu Colin N A Palmer Ruth Pakyz Laura Pascoe Felicity Payne Daniel Pearson Wolfgang Rathmann Annelli Sandbaek Avan Aihie Sayer Laura J Scott Stephen J Sharp Eric Sijbrands Andrew Singleton David S Siscovick Nicholas L Smith Thomas Sparsø Amy J Swift Holly Syddall Gudmar Thorleifsson Anke Tönjes Tiinamaija Tuomi Jaakko Tuomilehto Timo T Valle Gérard Waeber Andrew Walley Dawn M Waterworth Eleftheria Zeggini Jing Hua Zhao Thomas Illig H Erich Wichmann James F Wilson Cornelia van Duijn Frank B Hu Andrew D Morris Timothy M Frayling Andrew T Hattersley Unnur Thorsteinsdottir Kari Stefansson Peter Nilsson Ann-Christine Syvänen Alan R Shuldiner Mark Walker Stefan R Bornstein Peter Schwarz Gordon H Williams David M Nathan Johanna Kuusisto Markku Laakso Cyrus Cooper Michael Marmot Luigi Ferrucci Vincent Mooser Michael Stumvoll Ruth J F Loos David Altshuler Bruce M Psaty Jerome I Rotter Eric Boerwinkle Torben Hansen Oluf Pedersen Jose C Florez Mark I McCarthy Michael Boehnke Inês Barroso Robert Sladek Philippe Froguel James B Meigs Leif Groop Nicholas J Wareham Richard M Watanabe

Nat Genet 2010 Feb 17;42(2):142-8. Epub 2010 Jan 17.

Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922003PMC
February 2010

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

Authors:
Josée Dupuis Claudia Langenberg Inga Prokopenko Richa Saxena Nicole Soranzo Anne U Jackson Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Anna L Gloyn Cecilia M Lindgren Reedik Mägi Andrew P Morris Joshua Randall Toby Johnson Paul Elliott Denis Rybin Gudmar Thorleifsson Valgerdur Steinthorsdottir Peter Henneman Harald Grallert Abbas Dehghan Jouke Jan Hottenga Christopher S Franklin Pau Navarro Kijoung Song Anuj Goel John R B Perry Josephine M Egan Taina Lajunen Niels Grarup Thomas Sparsø Alex Doney Benjamin F Voight Heather M Stringham Man Li Stavroula Kanoni Peter Shrader Christine Cavalcanti-Proença Meena Kumari Lu Qi Nicholas J Timpson Christian Gieger Carina Zabena Ghislain Rocheleau Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Felicity Payne Rosa Maria Roccasecca François Pattou Praveen Sethupathy Kristin Ardlie Yavuz Ariyurek Beverley Balkau Philip Barter John P Beilby Yoav Ben-Shlomo Rafn Benediktsson Amanda J Bennett Sven Bergmann Murielle Bochud Eric Boerwinkle Amélie Bonnefond Lori L Bonnycastle Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Guillaume Charpentier Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Marilyn Cornelis Gabe Crawford Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Christian Dina Michael R Erdos Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Caroline S Fox Rune Frants Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Christopher J Groves Scott Grundy Rhian Gwilliam Ulf Gyllensten Samy Hadjadj Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Neelam Hassanali Caroline Hayward Simon C Heath Serge Hercberg Christian Herder Andrew A Hicks David R Hillman Aroon D Hingorani Albert Hofman Jennie Hui Joe Hung Bo Isomaa Paul R V Johnson Torben Jørgensen Antti Jula Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Valeriya Lyssenko Robert Mahley Massimo Mangino Alisa K Manning María Teresa Martínez-Larrad Jarred B McAteer Laura J McCulloch Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Mario A Morken Sutapa Mukherjee Silvia Naitza Narisu Narisu Matthew J Neville Ben A Oostra Marco Orrù Ruth Pakyz Colin N A Palmer Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Markus Perola Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Bruce M Psaty Wolfgang Rathmann Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Michael Roden Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Laura J Scott Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurethsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Toshiko Tanaka Barbara Thorand Jean Tichet Anke Tönjes Tiinamaija Tuomi André G Uitterlinden Ko Willems van Dijk Mandy van Hoek Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley G Bragi Walters Kim L Ward Hugh Watkins Michael N Weedon Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Eleftheria Zeggini Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Ruth J F Loos Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Andrew T Hattersley Kaisa Silander Veikko Salomaa George Davey Smith Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper George V Dedoussis Manuel Serrano-Ríos Andrew D Morris Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao James S Pankow Michael J Sampson Johanna Kuusisto Markku Laakso Torben Hansen Oluf Pedersen Peter Paul Pramstaller H Erich Wichmann Thomas Illig Igor Rudan Alan F Wright Michael Stumvoll Harry Campbell James F Wilson Richard N Bergman Thomas A Buchanan Francis S Collins Karen L Mohlke Jaakko Tuomilehto Timo T Valle David Altshuler Jerome I Rotter David S Siscovick Brenda W J H Penninx Dorret I Boomsma Panos Deloukas Timothy D Spector Timothy M Frayling Luigi Ferrucci Augustine Kong Unnur Thorsteinsdottir Kari Stefansson Cornelia M van Duijn Yurii S Aulchenko Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Dawn M Waterworth Peter Vollenweider Leena Peltonen Vincent Mooser Goncalo R Abecasis Nicholas J Wareham Robert Sladek Philippe Froguel Richard M Watanabe James B Meigs Leif Groop Michael Boehnke Mark I McCarthy Jose C Florez Inês Barroso

Nat Genet 2010 Feb 17;42(2):105-16. Epub 2010 Jan 17.

Department of Biostatistics, Boston University School of Public Health, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018764PMC
February 2010

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.

PLoS Genet 2009 Dec 11;5(12):e1000768. Epub 2009 Dec 11.

Departments of Medicine, Human Genetics, and Epidemiology and Biostatistics, Jewish General Hospital, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1000768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781107PMC
December 2009

Exogenous glucose-dependent insulinotropic polypeptide worsens post prandial hyperglycemia in type 2 diabetes.

Diabetes 2009 Jun 10;58(6):1342-9. Epub 2009 Mar 10.

National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db08-09
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http://dx.doi.org/10.2337/db08-0958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682676PMC
June 2009

Hormones in the naso-oropharynx: endocrine modulation of taste and smell.

Trends Endocrinol Metab 2009 May 7;20(4):163-70. Epub 2009 Apr 7.

Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.tem.2009.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732121PMC
May 2009

Role and development of GLP-1 receptor agonists in the management of diabetes.

Diabetes Metab Syndr Obes 2009 May;2:37

National Institutes of Health, National Institute on Aging, Intramural Research Program, Baltimore, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818016PMC
May 2009

The role of incretins in glucose homeostasis and diabetes treatment.

Pharmacol Rev 2008 Dec 12;60(4):470-512. Epub 2008 Dec 12.

National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA.

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http://pharmrev.aspetjournals.org/cgi/doi/10.1124/pr.108.000
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http://dx.doi.org/10.1124/pr.108.000604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696340PMC
December 2008

Reduced energy intake: the secret to a long and healthy life?

IBS J Sci 2007 Sep;2(2):35-39

Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, 5600 Nathan Shock Drive, Baltimore MD 21224.

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September 2007