Joseph S Takahashi

Cell Metab 2019 May 28;29(5):1078-1091.e5. Epub 2019 Feb 28.

Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

Genes Dev 2019 03 25;33(5-6):294-309. Epub 2019 Feb 25.

Department of Biology, Center for Biological Clocks Research, Texas A&M University, College Station, Texas 77843, USA.

G3 (Bethesda) 2018 12 10;8(12):3783-3790. Epub 2018 Dec 10.

Department of Genetics

Cell Rep 2018 10;25(1):1-9.e5

Department of Neurology and Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

Nat Commun 2018 03 19;9(1):1138. Epub 2018 Mar 19.

Department of Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.

Cell Syst 2018 Mar 7;6(3):314-328.e2. Epub 2018 Mar 7.

Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center and UTHealth, Houston, TX 77030, USA; Center for Precision Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Electronic address:

Nat Rev Genet 2017 03 19;18(3):164-179. Epub 2016 Dec 19.

Howard Hughes Medical Institute, Department of Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, NA4.118, Dallas, Texas 75390-9111, USA.

Cell Metab 2017 01;25(1):1-2

Howard Hughes Medical Institute and Department of Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9111 USA. Electronic address:

J Affect Disord 2017 Jan 11;208:248-254. Epub 2016 Oct 11.

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands; Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, CA, USA.

J Biol Chem 2016 Nov 19;291(46):23906-23914. Epub 2016 Sep 19.

From the Department of Neuroscience and

Nature 2016 11 2;539(7629):378-383. Epub 2016 Nov 2.

International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

Elife 2016 11 15;5. Epub 2016 Nov 15.

Department of Medical Genetics, University of Wisconsin-Madison, Madison, United States.

Sci Rep 2016 09 2;6:32453. Epub 2016 Sep 2.

International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Elife 2016 Sep 22;5. Epub 2016 Sep 22.

MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China.

Cell Metab 2016 Apr;23(4):610-21

Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX 77030, USA. Electronic address:

Proc Natl Acad Sci U S A 2016 Feb 28;113(6):E754-61. Epub 2015 Dec 28.

Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095;

Cell Rep 2015 Dec 19;13(9):1868-80. Epub 2015 Nov 19.

Department of Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

Nat Commun 2015 Nov 30;6:8587. Epub 2015 Nov 30.

Department of Biomedical Sciences, Program in Neuroscience, College of Medicine, Florida State University, 1115 West Call Street, Tallahassee, Florida 32306, USA.

Methods Enzymol 2015 26;551:285-321. Epub 2014 Dec 26.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

J Biol Rhythms 2015 Jun 13;30(3):163-82. Epub 2015 Jan 13.

Center for Complex Biological Systems, University of California, Irvine, Irvine, CA Department of Biological Chemistry, University of California, Irvine, Irvine, CA Division of Endocrinology, Department of Medicine, University of California, Irvine, Irvine, CA

Neuron 2015 Mar;85(5):1086-102

Department of Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba 305-8575, Japan. Electronic address:

J Neurosci 2015 Feb;35(5):1905-20

Department of Neuroscience and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, 75390,

Cell Rep 2015 Jan 24;10(1):1-7. Epub 2014 Dec 24.

Laboratory of Fluorescence Dynamics, Biomedical Engineering Department, University of California, Irvine, Irvine, CA 92037, USA; Center for Complex Biological System, University of California, Irvine, Irvine, CA 92037, USA. Electronic address:

Elife 2014 Dec 19;3. Epub 2014 Dec 19.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, United States.

Proc Natl Acad Sci U S A 2014 Dec 15;111(52):18757-62. Epub 2014 Dec 15.

McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI 53792;

Proc Natl Acad Sci U S A 2014 Nov 11;111(47):E5039-48. Epub 2014 Nov 11.

Department of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan; Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012, Japan

Elife 2014 Aug 15;3:e03674. Epub 2014 Aug 15.

Department of Pharmacology, University of Washington, Seattle, United States Howard Hughes Medical Institute, University of Washington, Seattle, United States

Front Endocrinol (Lausanne) 2013 22;4:195. Epub 2014 Jan 22.

Department of Neuroscience, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center , Dallas, TX , USA.

Mol Cell 2014 Mar 27;53(5):791-805. Epub 2014 Feb 27.

Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University, Seoul 151-742, South Korea. Electronic address:

Trends Cell Biol 2014 Feb 1;24(2):90-9. Epub 2013 Aug 1.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Insitute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

Science 2013 Dec;342(6165):1508-12

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.

J Biol Chem 2013 Dec 24;288(49):35277-86. Epub 2013 Oct 24.

From the Department of Neuroscience, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390.

Genome Biol 2013 Nov 29;14(11):140. Epub 2013 Nov 29.

Science 2013 Nov;342(6159):727-30

Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Mol Metab 2012 18;1(1-2):79-85. Epub 2012 Aug 18.

Program in Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA ; Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Nat Med 2013 Sep 11;19(9):1147-52. Epub 2013 Aug 11.

1] Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. [2] Division of Hypothalamic Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Cell Mol Life Sci 2013 Aug 16;70(16):2985-98. Epub 2012 Nov 16.

Department of Biochemistry and Molecular Biology, University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, TX 77030, USA,

Handb Exp Pharmacol 2013 (217):3-27

Department of Ophthalmology, University of Washington, 1959 NE Pacific St, 356485 BB-857 HSB, Seattle, WA 98195, USA.

Elife 2013 Apr 9;2:e00426. Epub 2013 Apr 9.

Center for Functional Genomics, Department of Neurobiology, Center for Sleep and Circadian Biology , Northwestern University , Evanston , United States.

Cell 2013 Feb;152(5):1091-105

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

PLoS Genet 2012 26;8(7):e1002835. Epub 2012 Jul 26.

Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.

Annu Rev Neurosci 2012 5;35:445-62. Epub 2012 Apr 5.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9111, USA.

Science 2012 Oct 30;338(6105):349-54. Epub 2012 Aug 30.

Department of Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.

Science 2012 Jul 31;337(6091):189-94. Epub 2012 May 31.

Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Proc Natl Acad Sci U S A 2012 Jul 2;109(29):11758-63. Epub 2012 Jul 2.

Department of Biological Chemistry, University of California, Irvine, CA 92697, USA.

Nature 2012 Mar 29;485(7396):62-8. Epub 2012 Mar 29.

Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA.

Proc Natl Acad Sci U S A 2012 Jan 19;109(1):101-6. Epub 2011 Dec 19.

Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

Adv Genet 2011 ;74:175-230

Department of Biology, Rider University, Lawrenceville, New Jersey, USA.

J Biol Chem 2011 Nov 15;286(45):39560-72. Epub 2011 Sep 15.

Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

Proc Natl Acad Sci U S A 2011 Sep 6;108 Suppl 3:15557-64. Epub 2011 Sep 6.

Department of Neuroscience, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.

Trends Neurosci 2011 Jul 12;34(7):349-58. Epub 2011 Jun 12.

Department of Neuroscience and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.

J Neurosci 2011 Apr;31(17):6449-56

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA.

Nature 2011 Jan;469(7331):476-8

Science 2010 Dec;330(6009):1349-54

Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

J Neurosci 2010 Dec;30(48):16314-23

Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710, USA.

Proc Natl Acad Sci U S A 2010 Nov 18;107(44):19049-54. Epub 2010 Oct 18.

Allen Institute for Brain Science, Seattle, WA 98103, USA.

Proc Natl Acad Sci U S A 2010 Nov 18;107(44):19090-5. Epub 2010 Oct 18.

School of Kinesiology, University of Illinois, Chicago, IL 60609, USA.

PLoS Biol 2010 Oct 12;8(10):e1000513. Epub 2010 Oct 12.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

Science 2010 Oct;330(6002):379-85

Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208-3520, USA.

Cell 2010 Sep;142(6):841-3

Department of Neuroscience, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, NA4.118, Dallas, TX 75390-9111, USA.

Nature 2010 Jul;466(7306):627-31

Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

Annu Rev Physiol 2010 ;72:551-77

Department of Psychiatry, University of California-San Diego, La Jolla, CA 92093, USA.

Proc Natl Acad Sci U S A 2010 May 19;107(18):8399-403. Epub 2010 Apr 19.

Department of Neurobiology and Physiology, Center for Functional Genomics, and Howard Hughes Medical Institute, Northwestern University, Evanston, IL 60208, USA.

Mol Cell 2009 Nov;36(3):417-30

Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL 32306, USA.

Proc Natl Acad Sci U S A 2009 Sep 2;106(37):15744-9. Epub 2009 Sep 2.

Comparative Systems Biology Team, Genomic Science Center, RIKEN, 1-7-22, Suehiro-cho, Tsurumi, Yokohama 230-0045, Japan.

Mamm Genome 2009 Aug 22;20(8):486-97. Epub 2009 Aug 22.

Department of Psychiatry and Behavioral Science, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

PLoS Genet 2009 Jul 24;5(7):e1000573. Epub 2009 Jul 24.

Department of Biological Chemistry, University of California Irvine, Irvine, California, United States of America.

Science 2009 May 19;324(5927):651-4. Epub 2009 Mar 19.

Department of Medicine, Northwestern University Feinberg School of Medicine, 2200 Campus Drive, Evanston, IL 60208-3500, USA.

Methods Enzymol 2005 ;393:230-9

Center for Functional Genomics, Northwestern University, Evanston, Illinois 60208, USA.

Methods Enzymol 2005 ;393:219-29

Center for Functional Genomics, Northwestern University, Evanston, Illinois 60208, USA.

Science 2008 Nov;322(5903):909-12

Howard Hughes Medical Institute, Northwestern University, Evanston, IL 60208, USA.

Methods Enzymol 2005 ;393:478-92

MusWorks, Inc, Rockville, Maryland 20855, USA.

Nat Rev Genet 2008 Oct;9(10):764-75

Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois 60208-3520, USA.

Cell 2008 Sep;134(5):728-42

Department of Biology, University of Virginia, Charlottesville, VA 22904, USA.

Science 2008 May;320(5878):949-53

Medical Research Council (MRC) Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

PLoS Genet 2008 May 9;4(5):e1000070. Epub 2008 May 9.

Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.

Neuron 2008 Apr;58(1):78-88

Faculty of Life Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT.

Doc Ophthalmol 2007 Nov 17;115(3):127-36. Epub 2007 Jul 17.

Department of Neurobiology and Physiology and Center for Functional Genomics, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA.

Vis Neurosci 2007 Jan-Feb;24(1):111-23

Department of Neurobiology and Physiology and Center for Functional Genomics, Northwestern University, Evanston, Illinois 60208, USA.

Physiol Genomics 2007 Sep 5;31(1):86-95. Epub 2007 Jun 5.

Department of Physiology, University of Kentucky, Lexington, Kentucky 40536, USA.

Cell 2007 Jun 26;129(5):1011-23. Epub 2007 Apr 26.

Howard Hughes Medical Institute, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA.

Cell 2007 May;129(3):605-16

Department of Biochemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.

Genetics 2007 May 3;176(1):675-83. Epub 2007 Apr 3.

Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA.

Proc Natl Acad Sci U S A 2007 Apr 22;104(15):6406-11. Epub 2007 Mar 22.

Department of Psychiatry and Center for Basic Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9070, USA.

Proc Natl Acad Sci U S A 2007 Feb 20;104(9):3342-7. Epub 2007 Feb 20.

Department of Neurobiology and Physiology, and Howard Hughes Medical Institute, Northwestern University, Evanston, IL 60208, USA.

PLoS Biol 2007 Feb;5(2):e34

Department of Molecular Biology, University of Geneva, Geneva, Switzerland.

PLoS Genet 2007 Feb 5;3(2):e33. Epub 2007 Jan 5.

Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, United States of America.

Cell 2007 Jan;128(1):22-3

Howard Hughes Medical Institute, Stanford University School of Medicine, 701-B Welch Road, Stanford, CA 94304, USA.

Biol Reprod 2006 Nov 26;75(5):778-84. Epub 2006 Jul 26.

Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois 60201, USA.

Physiol Genomics 2006 Nov 8;27(3):362-9. Epub 2006 Aug 8.

Department of Psychiatry and Behavioral Science, Northwestern University Feinberg School of Medicine, Chicago, USA.

Science 2006 Nov;314(5803):1304-8

Howard Hughes Medical Institute, Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA.

Hum Mol Genet 2006 Oct;15 Spec No 2:R271-7

Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA.

Nat Neurosci 2006 Aug 16;9(8):1041-9. Epub 2006 Jul 16.

Department of Molecular and Cellular Physiology and Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, USA.

Cell Metab 2006 Jul;4(1):3-4

Department of Biology, University of Virginia, Charlottesville, Virginia 22904, USA.

Proc Natl Acad Sci U S A 2006 Jun 5;103(24):9327-32. Epub 2006 Jun 5.

Center for Functional Genomics, Center for Sleep and Circadian Biology and Department of Neurobiology and Physiology, Northwestern University, 2205 Tech Drive, Evanston, IL 60208-3520, USA.

Behav Brain Res 2006 May 20;169(2):220-30. Epub 2006 Feb 20.

Department of Psychiatry and Behavioral Science, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

Trends Neurosci 2006 Apr 7;29(4):233-40. Epub 2006 Mar 7.

Center for Functional Genomics and Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA.

Genome Res 2006 Mar 3;16(3):436-40. Epub 2006 Feb 3.

Genetics Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Vis Neurosci 2005 Sep-Oct;22(5):619-29

Department of Neurobiology and Physiology and Center for Functional Genomics, Northwestern University, Evanston, Il 60208, USA.

Cell Cycle 2005 Jul 26;4(7):901-7. Epub 2005 Jul 26.

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

Invest Ophthalmol Vis Sci 2005 Jul;46(7):2540-51

Department of Human Genetics, University of Michigan, Ann Arbor, 48109, USA.

Proc Natl Acad Sci U S A 2005 Jun 20;102(26):9377-81. Epub 2005 Jun 20.

Department of Psychiatry and Center for Basic Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9070, USA.

Science 2005 May 21;308(5724):1043-5. Epub 2005 Apr 21.

Department of Neurology, Northwestern University, Evanston, IL 60208, USA.

Behav Genet 2005 Mar;35(2):189-98

Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, 60611, USA.

Proc Natl Acad Sci U S A 2005 Mar 2;102(9):3407-12. Epub 2005 Feb 2.

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

Proc Natl Acad Sci U S A 2005 Feb 7;102(7):2608-13. Epub 2005 Feb 7.

Department of Neurobiology and Physiology, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA.

Endocrinology 2005 Feb 28;146(2):870-8. Epub 2004 Oct 28.

Department of Psychiatry and Behavioral Science, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, Illinois 60611, USA.

J Neurosci 2005 Jan;25(2):404-8

Department of Biology, Washington University, St. Louis, Missouri 63130-4899, USA.

Vision Res 2004 Dec;44(28):3335-45

Department of Neurobiology and Physiology and Center for Functional Genomics, Northwestern University, 2205 Tech Drive, Hogan Hall 2-140, Evanston, IL 60208, USA.

Brain Res Mol Brain Res 2004 Dec;132(2):105-15

Dept. Anatomy and Neurobiology, University of Tennessee Health Science Center, 855 Monroe Ave., Memphis, TN 38163, United States.

Curr Biol 2004 Dec;14(24):2289-95

Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

J Biol Rhythms 2004 Oct;19(5):339-47

Howard Hughes Medical Institute, Department of Neurobiology & Physiology, Northwestern University, Evanston, IL 60208-3520, USA.

Genetica 2004 Sep;122(1):51-64

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.