Joseph Replogle

Joseph Replogle

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Joseph Replogle

Joseph Replogle

Publications by authors named "Joseph Replogle"

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Exploring genetic interaction manifolds constructed from rich single-cell phenotypes.

Science 2019 08 8;365(6455):786-793. Epub 2019 Aug 8.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1126/science.aax4438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746554PMC
August 2019

Genetic architecture of age-related cognitive decline in African Americans.

Neurol Genet 2017 Feb 21;3(1):e125. Epub 2016 Dec 21.

Program in Translational NeuroPsychiatric Genomics (T.R., L.B.C., J.M.R., P.L.D.J.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Center for Neurologic Disease (T.R., A.W., A.K., P.L.D.J.), Department of Neurology, and Division of Genetics (T.R., L.B.C., P.L.D.J.), Department of Medicine, Brigham and Women's Hospital, Boston, MA; Harvard Medical School (T.R., L.B.C., P.L.D.J.), Boston, MA; Program in Medical and Population genetics (T.R., L.B.C., C.M., J.M.R., P.L.D.J.), The Broad Institute, Cambridge, MA; Section of Genetic Medicine (B.S.), Department of Medicine, and Institute for Genomics and Systems Biology (B.S.), University of Chicago, IL; Indiana University Center for Aging Research (H.C.H.); Department of Psychiatry (F.W.U., H.C.H., K.S.H.), Department of Biostatistics (S.G.), Indiana University School of Medicine; Department of Medical and Molecular Genetics (J.M., T.F.), Indiana University, Indianapolis; Rush Institute for Healthy Aging (D.A.V.), Department of Internal Medicine, Department of Neurology (L.B., D.A.B.), and Rush Alzheimer's Disease Center (L.Y., L.B., D.A.B.), Rush University Medical Center, Chicago, IL. T.R. is currently affiliated with Ronald M. Loeb Center for Alzheimer's Disease, Departments of Neuroscience, and Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York.

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http://dx.doi.org/10.1212/NXG.0000000000000125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206965PMC
February 2017

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.

Neurol Genet 2016 Aug 26;2(4):e90. Epub 2016 Jul 26.

Ann Romney Center for Neurologic Diseases (G.C., C.C.W., P.A.W., M.C., J.M.R., L.R.G., N.E.C., K.J.R., L.B.C., P.L.D.J., E.M.B.), Program in Translational NeuroPsychiatric Genomics (G.C., C.C.W., P.A.W., M.C., J.M.R., L.R.G., N.E.C., K.J.R., L.B.C., P.L.D.J., E.M.B.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Center for Alzheimer's Research and Treatment (K.A.J., R.A.S.), Department of Neurology, Brigham and Women's Hospital, Boston, MA; Program in Medical and Population Genetics (G.C., C.C.W., P.A.W., M.C., J.M.R., L.R.G., N.E.C., K.J.R., L.B.C., P.L.D.J., E.M.B.), Broad Institute, Cambridge, MA; Harvard Medical School (G.C., J.M.R., K.J.R., K.A.J., L.B.C., R.A.S., P.L.D.J., E.M.B.), Boston, MA; Department of Neurology (K.A.J., R.A.S.), Massachusetts General Hospital, Boston; and Rush Alzheimer's Disease Center (J.A.S., D.A.B.), Rush University Medical Center, Chicago, IL.

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http://dx.doi.org/10.1212/NXG.0000000000000090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962525PMC
August 2016

Nucleosomes impede Cas9 access to DNA in vivo and in vitro.

Elife 2016 03 17;5. Epub 2016 Mar 17.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.

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http://dx.doi.org/10.7554/eLife.12677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861601PMC
March 2016

Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.

Hum Mol Genet 2016 Jan 24;25(2):404-17. Epub 2015 Nov 24.

Ann Romney Center for Neurologic Diseases, Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Broad Institute at Harvard University and MIT, NRB-641, 77 Avenue Louis Pasteur, Boston, MA 02115, USA and

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http://dx.doi.org/10.1093/hmg/ddv474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881829PMC
January 2016

Reply: To PMID 25545807.

Ann Neurol 2015 Oct 22;78(4):659-60. Epub 2015 Aug 22.

Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, MA.

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http://doi.wiley.com/10.1002/ana.24456
Publisher Site
http://dx.doi.org/10.1002/ana.24456DOI Listing
October 2015

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

Ann Neurol 2015 Mar;77(3):469-77

Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, MA; Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA; Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1002/ana.24337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461024PMC
March 2015

Epigenomics in translational research.

Transl Res 2015 Jan 5;165(1):7-11. Epub 2014 Oct 5.

Department of Neurology, Brigham and Women's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2014.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533922PMC
January 2015

CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility.

Hum Mol Genet 2014 May 30;23(10):2729-36. Epub 2013 Dec 30.

Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/hmg/ddt666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990171PMC
May 2014

Interindividual variation in human T regulatory cells.

Proc Natl Acad Sci U S A 2014 Mar 7;111(12):E1111-20. Epub 2014 Mar 7.

Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115.

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http://dx.doi.org/10.1073/pnas.1401343111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970507PMC
March 2014

Common risk alleles for inflammatory diseases are targets of recent positive selection.

Am J Hum Genet 2013 Apr 21;92(4):517-29. Epub 2013 Mar 21.

Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham & Women's Hospital, Boston, MA 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297130010
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http://dx.doi.org/10.1016/j.ajhg.2013.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617371PMC
April 2013