Joseph M Massaro

Joseph M Massaro

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Relations of liver fat with prevalent and incident chronic kidney disease in the Framingham Heart Study: A secondary analysis.

Liver Int 2019 Aug 24;39(8):1535-1544. Epub 2019 May 24.

National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/liv.14125
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http://dx.doi.org/10.1111/liv.14125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675651PMC
August 2019

Increasing Liver Fat Is Associated With Incident Cardiovascular Risk Factors.

Clin Gastroenterol Hepatol 2019 Aug 9. Epub 2019 Aug 9.

Section of Gastroenterology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.08.003DOI Listing
August 2019

New-onset Atrial Fibrillation as a Sepsis Defining Organ Failure.

Ann Am Thorac Soc 2019 Jun 26. Epub 2019 Jun 26.

Boston University School of Medicine, 12259, Department of Medicine, The Pulmonary Center, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1513/AnnalsATS.201902-176RLDOI Listing
June 2019

Liver Fat Is Associated With Markers of Inflammation and Oxidative Stress in Analysis of Data From the Framingham Heart Study.

Clin Gastroenterol Hepatol 2019 May 23;17(6):1157-1164.e4. Epub 2018 Nov 23.

Section of Gastroenterology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475462PMC
May 2019

Association of an HDL Apolipoproteomic Score With Coronary Atherosclerosis and Cardiovascular Death.

J Am Coll Cardiol 2019 May;73(17):2135-2145

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; Department of Medicine, Harvard Medical School, Boston, Massachusetts; Baim Institute for Clinical Research, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2019.01.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501819PMC
May 2019

Density and morphology of coronary artery calcium for the prediction of cardiovascular events: insights from the Framingham Heart Study.

Eur Radiol 2019 May 2. Epub 2019 May 2.

Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, 165 Cambridge Street, Suite 400, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00330-019-06223-7DOI Listing
May 2019

Parental non-alcoholic fatty liver disease increases risk of non-alcoholic fatty liver disease in offspring.

Liver Int 2019 Apr 25;39(4):740-747. Epub 2018 Sep 25.

Division of Gastroenterology, Department of Medicine and Division of Epidemiology, Department of Family and Preventive, University of California at San Diego, La Jolla, California.

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http://doi.wiley.com/10.1111/liv.13956
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http://dx.doi.org/10.1111/liv.13956DOI Listing
April 2019

A novel confidence interval for a single proportion in the presence of clustered binary outcome data.

Stat Methods Med Res 2019 Jan 23:962280218823231. Epub 2019 Jan 23.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1177/0962280218823231DOI Listing
January 2019

Benefit and Risk of Prolonged DAPT After Coronary Stenting in Women.

Circ Cardiovasc Interv 2018 08;11(8):e005308

Department of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (N.C.B., L.M.).

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https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.11
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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005308DOI Listing
August 2018

Age and Graphomotor Decision Making Assessed with the Digital Clock Drawing Test: The Framingham Heart Study.

J Alzheimers Dis 2017 ;60(4):1611-1620

Department of Geriatrics and Gerontology and the Department of Psychology, New Jersey Institute for Successful Aging, Rowan University, School of Osteopathic Medicine, Stratford, NJ, USA.

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http://dx.doi.org/10.3233/JAD-170444DOI Listing
July 2018

Protein Biomarkers of Cardiovascular Disease and Mortality in the Community.

J Am Heart Assoc 2018 07 13;7(14). Epub 2018 Jul 13.

National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA.

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http://dx.doi.org/10.1161/JAHA.117.008108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064847PMC
July 2018

Visceral and Intrahepatic Fat Are Associated with Cardiometabolic Risk Factors Above Other Ectopic Fat Depots: The Framingham Heart Study.

Am J Med 2018 06 5;131(6):684-692.e12. Epub 2018 Mar 5.

Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Md; Framingham Heart Study, Framingham, Mass; Department of Medicine, Division of Gastroenterology, Boston University School of Medicine, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2018.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964004PMC
June 2018

Aortic Arch Width and Cardiovascular Disease in Men and Women in the Community.

J Am Heart Assoc 2018 06 16;7(12). Epub 2018 Jun 16.

The National Heart, Lung, and Blood Institute's FHS (Framingham Heart Study), Framingham, MA

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http://dx.doi.org/10.1161/JAHA.117.008057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220524PMC
June 2018

Evidence on the Validity of a Comprehensive Health Risk Index and Implications for Ambulatory Care and Population Health Management.

J Ambul Care Manage 2017 Oct/Dec;40(4):297-304

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts (Drs Massaro and D'Agostino); Section of General Internal Medicine (Dr Murabito) and Department of Neurology (Dr Au), Boston University School of Medicine, Boston Massachusetts; National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts (Drs Massaro, Murabito, Au, and D'Agostino); Institute for Health Metrics and Evaluation, University of Washington, Seattle (Ms Carnahan and Drs Murray and Lim); The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire (Ms Morgan and Drs Fisher and Nelson); and Department of Mathematics and Statistics, Boston University, Boston, Massachusetts (Dr D'Agostino).

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http://dx.doi.org/10.1097/JAC.0000000000000177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578915PMC
May 2018

Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib.

Pediatr Res 2018 05 28;83(5):982-992. Epub 2018 Feb 28.

The Vascular Biology Program and The Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1038/pr.2018.9DOI Listing
May 2018

Cardiovascular Risk Prediction Functions Underestimate Risk in HIV Infection.

Circulation 2018 05 14;137(21):2203-2214. Epub 2018 Feb 14.

Massachusetts General Hospital, Boston. Department of Mathematics and Statistics (J.P., R.B.D.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157923PMC
May 2018

Observational and Genetic Associations of Resting Heart Rate With Aortic Valve Calcium.

Am J Cardiol 2018 05 13;121(10):1246-1252. Epub 2018 Feb 13.

Division of Intramural Research, National Heart Lung and Blood Institute (NHLBI) and NHLBI Framingham Heart Study, Framingham Massachusetts; Cardiology Section, Boston Veterans Administration Healthcare System, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2018.01.048DOI Listing
May 2018

Longitudinal Associations of Pericardial and Intrathoracic Fat With Progression of Coronary Artery Calcium (from the Framingham Heart Study).

Am J Cardiol 2018 01 19;121(2):162-167. Epub 2017 Oct 19.

National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts; Department of Medicine, Section of Gastroenterology, Boston University School of Medicine, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742312PMC
January 2018

Maintenance of Ideal Cardiovascular Health and Coronary Artery Calcium Progression in Low-Risk Men and Women in the Framingham Heart Study.

Circ Cardiovasc Imaging 2018 01;11(1):e006209

From the National Heart, Lung and Blood Institute's Intramural Research Program, Framingham Heart Study, MA (S.-J.H., C.S.F., C.J.O.); Population Sciences Branch, Division of Intramural Research (S.-J.H.) and Office of Biostatistics Research, Division of Cardiovascular Sciences (Y.P.F.), NHLBI, NIH, Bethesda, MD; World Health Organization Department for Management of Non-Communicable Diseases, Disability, Violence and Injury Prevention (NVI), Geneva, Switzerland (O.O.); Department of Mathematics and Statistics (J.M.M.) and Section of Biomedical Genetics, School of Medicine (X.Z.), Boston University, MA; Department of Radiology, Massachusetts General Hospital, Boston (U.H.); Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (C.S.F.); and Cardiology Section, Boston Veteran's Administration Healthcare, MA (C.J.O.).

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http://dx.doi.org/10.1161/CIRCIMAGING.117.006209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761687PMC
January 2018

Increased Aortic Diameters on Multidetector Computed Tomographic Scan Are Independent Predictors of Incident Adverse Cardiovascular Events: The Framingham Heart Study.

Circ Cardiovasc Imaging 2017 Dec;10(12)

From the National Heart, Lung and Blood Institute's Framingham Heart Study, MA (S.Q., J.M.M., M.L.C., R.B.D., U.H., C.J.O.); Department of Biostatistics, Boston University School of Public Health, MA (J.M.M., R.B.D.); Cardiovascular Imaging Core Laboratory, Beth Israel Deaconess Medical Center, Boston, MA (M.L.C.); Cardiac MR PET CT Program and Department of Radiology, Massachusetts General Hospital, Boston (U.H.); Cardiology Section, Boston Veteran's Administration Healthcare, MA (S.Q., C.J.O.); Division of Aging, Brigham and Women's Hospital, Boston, MA (S.Q.); and Harvard Medical School, Boston, MA (S.Q., U.H., C.J.O.).

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http://dx.doi.org/10.1161/CIRCIMAGING.117.006776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728667PMC
December 2017

Rationale of a novel study design for the BIOFLOW V study, a prospective, randomized multicenter study to assess the safety and efficacy of the Orsiro sirolimus-eluting coronary stent system using a Bayesian approach.

Am Heart J 2017 Nov 5;193:35-45. Epub 2017 Aug 5.

Baim Institute for Clinical Research, Boston, MA; Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2017.08.001DOI Listing
November 2017

Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study.

Atherosclerosis 2017 10 23;265:305-311. Epub 2017 Jun 23.

Department of Neurology, Boston University School of Medicine, 72 East Concord Street, C-3, Boston, MA 02118, USA; National Heart, Lung, and Blood Institute's Framingham Study, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA 01702, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.06.919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617776PMC
October 2017

Coronary Artery Calcium Distribution Is an Independent Predictor of Incident Major Coronary Heart Disease Events: Results From the Framingham Heart Study.

Circ Cardiovasc Imaging 2017 10;10(10)

From the Knight Cardiovascular Institute, Oregon Health and Science University, Portland (M.F.); Department of Radiology (M.F., T.L., K.G., U.H.) and Cardiac MR PET CT Program (M.F., T.L., K.G., U.H.), Massachusetts General Hospital and Harvard Medical School, Boston; Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (K.M.P.); Department of Radiology, First Affiliated Hospital of China Medical University, Shenyang, China (T.L.); Department of Mathematics, Boston University, MA (K.B., J.M.M., R.B.D.); The Framingham Heart Study of the National Heart, Lung and Blood Institute, MA (C.J.O.); and Cardiology Section, VA Boston Healthcare System, West Roxbury, MA (C.J.O.).

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http://dx.doi.org/10.1161/CIRCIMAGING.117.006592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659296PMC
October 2017

Lesion Complexity and Outcomes of Extended Dual Antiplatelet Therapy After Percutaneous Coronary Intervention.

J Am Coll Cardiol 2017 Oct;70(18):2213-2223

Baim Institute for Clinical Research, Boston, Massachusetts; Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2017.09.011DOI Listing
October 2017

Guideline-Based Statin Eligibility, Cancer Events, and Noncardiovascular Mortality in the Framingham Heart Study.

J Clin Oncol 2017 Sep 12;35(25):2927-2933. Epub 2017 Jul 12.

Amit Pursnani, NorthShore University Health System, Evanston, IL; Amit Pursnani and Udo Hoffmann, Massachusetts General Hospital, Harvard Medical School; Joseph M. Massaro and Ralph B. D'Agostino Sr, Boston University; Christopher J. O'Donnell, Boston Veterans Administration Healthcare, Boston; Joseph M. Massaro, Ralph B. D'Agostino Sr, and Christopher J. O'Donnell, The Framingham Heart Study of the National Heart, Lung and Blood Institute and Boston University, Framingham, MA; and Christopher J. O'Donnell, National Heart, Lung and Blood Institute, Bethesda, MD.

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http://dx.doi.org/10.1200/JCO.2016.71.3594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578389PMC
September 2017

Upper Body Subcutaneous Fat Is Associated with Cardiometabolic Risk Factors.

Am J Med 2017 08 24;130(8):958-966.e1. Epub 2017 Feb 24.

Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Md; Framingham Heart Study, Mass; Department of Medicine, Division of Gastroenterology, Boston University School of Medicine, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2017.01.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522762PMC
August 2017

The Association between Non-Invasive Hepatic Fibrosis Markers and Cardiometabolic Risk Factors in the Framingham Heart Study.

PLoS One 2016 24;11(6):e0157517. Epub 2016 Jun 24.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157517PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920364PMC
July 2017

Myocardial Infarction Risk After Discontinuation of Thienopyridine Therapy in the Randomized DAPT Study (Dual Antiplatelet Therapy).

Circulation 2017 May 22;135(18):1720-1732. Epub 2017 Feb 22.

From Massachusetts General Hospital, Boston (A.C.S.S.); Baim Institute for Clinical Research (formerly Harvard Clinical Research Institute), Boston, MA (A.C.S.S., D.E.C., R.W.Y., R.B.D'A., J.M.M., W.-H.H., L.M.); Brigham and Women's Hospital, Boston, MA (A.C.S.S., L.M.); Christ Hospital, Heart and Vascular Center and Lindner Center for Research and Education, Cincinnati, OH (D.J.K.); and Beth Israel Deaconess Medical Center, Boston, MA (D.E.C., R.W.Y.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469374PMC
May 2017

Mortality Following Cardiovascular and Bleeding Events Occurring Beyond 1 Year After Coronary Stenting: A Secondary Analysis of the Dual Antiplatelet Therapy (DAPT) Study.

JAMA Cardiol 2017 05;2(5):478-487

Harvard Medical School, Boston, Massachusetts 3Center for Clinical Biometrics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 5Baim Institute for Clinical Research, Boston, Massachusetts 14Division of Cardiology, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamacardio.2017.0063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814981PMC
May 2017

Relation of Risk Factors and Abdominal Aortic Calcium to Progression of Coronary Artery Calcium (from the Framingham Heart Study).

Am J Cardiol 2017 05 1;119(10):1584-1589. Epub 2017 Mar 1.

The National Heart, Lung, and Blood Institute's the Framingham Heart Study, Framingham, Massachusetts; Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Cardiology Section, Department of Medicine, Boston Veteran's Administration Healthcare, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734670PMC
May 2017

Extended Duration Dual Antiplatelet Therapy After Coronary Stenting Among Patients With Peripheral Arterial Disease: A Subanalysis of the Dual Antiplatelet Therapy Study.

JACC Cardiovasc Interv 2017 05;10(9):942-954

Division of Cardiology and Center for Clinical Biometrics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Baim Institute for Clinical Research, Boston, Massachusetts. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19368798173032
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http://dx.doi.org/10.1016/j.jcin.2017.02.013DOI Listing
May 2017

Greater remnant lipoprotein cholesterol reduction with pitavastatin compared with pravastatin in HIV-infected patients.

AIDS 2017 04;31(7):965-971

aDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas bJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore cDepartment of Critical Care Medicine, National Institutes of Health, Bethesda, Maryland dDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts eAtherotech Diagnostics Laboratory, Birmingham fKowa Pharmaceuticals America, Inc., Montgomery, Alabama gCGH Medical Center, University of Illinois School of Medicine, Peoria, Illinois, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001423DOI Listing
April 2017

Relation of Iliac Artery Calcium With Adiposity Measures and Peripheral Artery Disease.

Am J Cardiol 2017 04 25;119(8):1217-1223. Epub 2017 Jan 25.

Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts; Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2016.12.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385098PMC
April 2017

Bi-directional analysis between fatty liver and cardiovascular disease risk factors.

J Hepatol 2017 02 10;66(2):390-397. Epub 2016 Oct 10.

Division of Gastroenterology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250546PMC
February 2017

Incident Type 2 Myocardial Infarction in a Cohort of Patients Undergoing Coronary or Peripheral Arterial Angiography.

Circulation 2017 Jan 21;135(2):116-127. Epub 2016 Nov 21.

From Cardiology Division, Massachusetts General Hospital, Boston (H.K.G., A.M., N.E.I., M.L.S., A.M.B., J.E.H., J.L.J.); Baim Institute for Clinical Research, Boston, MA (H.K.G., Y.L., A.L., J.M.M., R.B.D'A., J.L.J.); Department of Biostatistics, Boston University, MA (Y.L., J.M.M.); Department of Mathematics and Statistics, Boston University, MA (A.L., R.B.D'A.); Cardiology Division, Radboud UMC, Nijmegen, the Netherlands (R.R.J.v.K.); Cardiology Division, Maastricht UMC, Maastricht, the Netherlands (R.R.J.v.K.); Cardiology Division, Beth Israel Deaconess Medical Center, Boston, MA (S.R.M.); Cardiology Division, Brigham and Women Hospital, Boston, MA (N.P.K.); Cardiology Division, Yale University School of Medicine, New Haven, CT (P.U.G.); Cardiology Division, VA Connecticut Healthcare System, West Haven, CT (P.U.G.); and Cardiology Division, Case Western Reserve University/Metrohealth Campus, Cleveland, OH (A.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023052DOI Listing
January 2017

Thyroid function and cardiovascular disease risk factors in euthyroid adults: a cross-sectional and longitudinal study.

Clin Endocrinol (Oxf) 2016 Dec 14;85(6):932-941. Epub 2016 Jul 14.

National Heart, Lung and Blood Institute's Division of Intramural Research, The Framingham Heart Study, Population Studies Branch, Framingham, Boston, MA, USA.

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http://dx.doi.org/10.1111/cen.13124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589187PMC
December 2016

Impact of Optimal Medical Therapy in the Dual Antiplatelet Therapy Study.

Circulation 2016 Oct 30;134(14):989-998. Epub 2016 Aug 30.

From Division of Cardiology and Center for Clinical Biometrics, Department of Medicine, Brigham and Women's Hospital, Boston, MA (C.D.R., L.M.); Harvard Clinical Research Institute, Boston, MA (R.W.Y., D.E.C., W.-H.H., L.M.); Harvard Medical School, Boston, MA (R.W.Y., L.M.); Division of Cardiology, University of Pennsylvania Medical Center, Philadelphia (A.N.); Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, MA (R.W.Y., D.E.C.); Department of Biostatistics, Boston University School of Public Heath, MA (J.M.M.); The Christ Hospital Heart and Vascular Center and The Lindner Center for Research and Education, Cincinnati, OH (D.J.K.); Université Paris-Diderot, INSERM U-1148, Hôpital Bichat, Département Hospitalo-Universitaire Fibrosis, Inflammation, and Remodeling, Assistance Publique-Hôpitaux de Paris, Paris, France (P.G.S.); and National Heart and Lung Institute, Institute of Cardiovascular Medicine and Science, Royal Brompton Hospital, Imperial College, London, UK (P.G.S.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421387PMC
October 2016

Association of Changes in Abdominal Fat Quantity and Quality With Incident Cardiovascular Disease Risk Factors.

J Am Coll Cardiol 2016 10;68(14):1509-21

National Heart, Lung, and Blood Institute's Division of Intramural Research, the Framingham Heart Study, and the Population Studies Branch, Framingham, Massachusetts; Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.06.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599249PMC
October 2016

Lung Cancer Screening Eligibility in the Community: Cardiovascular Risk Factors, Coronary Artery Calcification, and Cardiovascular Events.

Circulation 2016 09;134(12):897-9

From Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (M.T.L., U.H.); Cardiology Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (O.K.O.); The Framingham Heart Study of the National Heart, Lung and Blood Institute (NHLBI) and Boston University, Framingham, MA (O.K.O., J.M.M., R.B.D., C.J.O., U.H.); Department of Biostatistics, Boston University School of Public Health, Boston, MA (J.M.M.); Department of Mathematics and Statistics, Boston University, Boston, MA (R.B.D.); Division of Intramural Research, NHLBI, Bethesda, MD (C.J.O.), and Cardiology Section, Department of Medicine, Boston Veteran's Administration Healthcare System, Harvard Medical School, Boston, MA (C.J.O.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031246PMC
September 2016

Development and Validation of the Framingham Steatosis Index to Identify Persons With Hepatic Steatosis.

Clin Gastroenterol Hepatol 2016 08 1;14(8):1172-1180.e2. Epub 2016 Apr 1.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts; Division of Endocrinology, Hypertension, and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.cgh.2016.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955680PMC
August 2016

Residential Proximity to Major Roads, Exposure to Fine Particulate Matter, and Coronary Artery Calcium: The Framingham Heart Study.

Arterioscler Thromb Vasc Biol 2016 08 16;36(8):1679-85. Epub 2016 Jun 16.

From the Department of Epidemiology (K.S.D., E.H.W., W.L., J.S., M.A.M.), Department of Environmental Health (E.H.W., J.S., P.K.), and Department of Biostatistics (B.A.C.), Harvard T.H. Chan School of Public Health, Boston, MA; Cardiovascular Epidemiology Research Unit, Department of Cardiology, Beth Israel Deaconess Medical Center (K.S.D., E.H.W., W.L., M.B.R., P.L.L., M.A.M.), Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center (M.B.R.), Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital (U.H.), and Cardiovascular Medicine, Brigham and Women's Hospital (C.J.O.), Harvard Medical School, Boston, MA; Unit of Environmental Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden (P.L.L.); Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel (I.K.); National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA (R.B.D., J.M.M., C.J.O.); Department of Mathematics and Statistics, Boston University, MA (R.B.D.); Department of Biostatistics, Boston University School of Public Health, Boston, MA (J.M.M.); and Cardiology Section, Department of Medicine, Boston Veteran's Administration Health System, Boston, MA (C.J.O.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965287PMC
August 2016

The Contribution of Autonomic Imbalance to the Development of Metabolic Syndrome.

Psychosom Med 2016 05;78(4):474-80

From the Cincinnati VA Medical Center (Perry, Wulsin) and University of Cincinnati College of Medicine (Wulsin), Cincinnati, Ohio; Cincinnati VA Medical Center and University of Cincinnati (Horn), Cincinnati, Ohio; Department of Biostatistics, Boston University School of Public Health (Massaro), Boston, Massachusetts; and Department of Mathematics and Statistics, Boston University (D'Agostino), Boston, Massachusetts.

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http://dx.doi.org/10.1097/PSY.0000000000000290DOI Listing
May 2016

Circulating Sex Steroids and Vascular Calcification in Community-Dwelling Men: The Framingham Heart Study.

J Clin Endocrinol Metab 2016 05 1;101(5):2160-7. Epub 2016 Mar 1.

Hebrew SeniorLife Institute for Aging Research (T.G.T.), Roslindale, Massachusetts 02131; Research Program on Men's Health, Aging and Metabolism (T.G.T., S.Bh., S.Ba.), Brigham and Women's Hospital, Boston, Massachusetts 02115; Harvard Medical School (T.G.T., C.J.O., S.Bh., U.H., S.Ba.), Boston, Massachusetts 02115; National Heart, Lung and Blood Institute's Framingham Heart Study (C.J.O., J.M.M., R.S.V., R.B.D.), Framingham, Massachusetts 01702; Cardiology Division (C.J.O.), Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114; Department of Biostatistics (J.M.M.), Boston University School of Public Health, Boston, Massachusetts 02118; Department of Radiology (U.H.), Massachusetts General Hospital, Boston, Massachusetts 02114; Section of Preventive Medicine and Epidemiology (R.S.V.), Boston University School of Medicine, Boston, Massachusetts 02118; and Department of Mathematics (R.B.D.), Boston University, Boston, Massachusetts 02215.

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http://dx.doi.org/10.1210/jc.2015-4299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870846PMC
May 2016

Diabetes Mellitus and Prevention of Late Myocardial Infarction After Coronary Stenting in the Randomized Dual Antiplatelet Therapy Study.

Circulation 2016 May 18;133(18):1772-82. Epub 2016 Mar 18.

From Monash Heart and Monash University, Melbourne, Australia (I.T.M., W.-H.H.); Montreal Heart Institute, Université de Montréal, Québec, Canada (J.-F.T.); The Christ Hospital Heart and Vascular Center and The Lindner Center for Research and Education, Cincinnati, OH (D.J.K.); Beth Israel Deaconess Medical Center, Boston, MA (D.E.C.); Harvard Clinical Research Institute, Boston, MA (D.E.C., R.W.Y., J.M.M., L.M.); Harvard Medical School, Boston, MA (D.E.C., R.W.Y., L.M.); The Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, MA (R.W.Y.); Lenox Hill Hospital, New York, NY (K.N.G.); Stanford University, Stanford, CA (D.P.L.); Université Paris-Diderot, INSERM U-1148, Hôpital Bichat, Département Hospitalo-Universitaire Fibrosis, Inflammation, and Remodeling, Assistance Publique-Hôpitaux de Paris - all in Paris, National Heart and Lung Institute, Imperial College, Royal Brompton Hospital, London, United Kingdom (P.G.S.); Henry Ford Medical Group, Detroit, MI (W.D.W.); Mayo Clinic, Rochester, MN (D.R.H.); Institute for Health Policy Studies, University of California, San Francisco (R.G.B.); Jan Pawel II Hospital Krakow, Poland (J.T.); Boston University School of Public Health, Boston, MA (J.M.M.); and Brigham and Women's Hospital, Boston, MA (L.M.).

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May 2016

DAPT Score Utility for Risk Prediction in Patients With or Without Previous Myocardial Infarction.

J Am Coll Cardiol 2016 May 1;67(21):2492-502. Epub 2016 Apr 1.

Harvard Medical School, Boston, Massachusetts; Harvard Clinical Research Institute, Boston, Massachusetts; Department of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.03.485DOI Listing
May 2016

Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation.

J Am Heart Assoc 2016 05 4;5(5). Epub 2016 May 4.

National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA Division of Endocrinology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.115.002936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889173PMC
May 2016

Lifestyle factors and indices of kidney function in the Framingham Heart Study.

Am J Nephrol 2015 20;41(4-5):267-74. Epub 2015 May 20.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Mass., USA.

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http://dx.doi.org/10.1159/000430868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514559PMC
April 2016

Digital Connectedness in the Framingham Heart Study.

J Am Heart Assoc 2016 Apr 13;5(4):e003193. Epub 2016 Apr 13.

Framingham Heart Study, Framingham, MA Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.116.003193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859293PMC
April 2016

Remnant Lipoprotein Cholesterol and Incident Coronary Heart Disease: The Jackson Heart and Framingham Offspring Cohort Studies.

J Am Heart Assoc 2016 04 29;5(5). Epub 2016 Apr 29.

Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD CGH Medical Center, Sterling, IL University of Illinois School of Medicine, Peoria, IL.

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http://dx.doi.org/10.1161/JAHA.115.002765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889167PMC
April 2016

Pitavastatin 4 mg Provides Significantly Greater Reduction in Remnant Lipoprotein Cholesterol Compared With Pravastatin 40 mg: Results from the Short-term Phase IV PREVAIL US Trial in Patients With Primary Hyperlipidemia or Mixed Dyslipidemia.

Clin Ther 2016 Mar 26;38(3):603-9. Epub 2016 Feb 26.

Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland; CGH Medical Center, Sterling, Illinois and the University of Illinois School of Medicine, Peoria, Illinois.

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http://dx.doi.org/10.1016/j.clinthera.2016.02.001DOI Listing
March 2016

Adipose tissue attenuation as a marker of adipose tissue quality: Associations with six-year changes in body weight.

Obesity (Silver Spring) 2016 Feb 23;24(2):499-505. Epub 2015 Dec 23.

Division of Intramural Research and the Center for Population Studies, National Heart, Lung, and Blood Institute, Framingham, Massachusetts, USA.

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http://dx.doi.org/10.1002/oby.21337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770559PMC
February 2016

Biomarkers of oxidative stress are associated with frailty: the Framingham Offspring Study.

Age (Dordr) 2016 Feb 23;38(1). Epub 2015 Dec 23.

National Heart, Lung and Blood Institute's Framingham Heart Study, 73 Mount Wayte Ave, Suite 2, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1007/s11357-015-9864-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005887PMC
February 2016

Cardiovascular Event Prediction and Risk Reclassification by Coronary, Aortic, and Valvular Calcification in the Framingham Heart Study.

J Am Heart Assoc 2016 Feb 22;5(2). Epub 2016 Feb 22.

Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA The Framingham Heart Study of the National Heart, Lung and Blood Institute (NHLBI) and Boston University, Framingham, MA Division of Intramural Research, NHLBI, Bethesda, MD.

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http://dx.doi.org/10.1161/JAHA.115.003144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802453PMC
February 2016

Association Between Prolactin and Incidence of Cardiovascular Risk Factors in the Framingham Heart Study.

J Am Heart Assoc 2016 Feb 23;5(2). Epub 2016 Feb 23.

National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA Department of Endocrinology, Hypertension and Diabetes, Brigham and Women's Hospital and Harvard Medical School, Boston, MA National Heart, Lung, and Blood Institute, Bethesda, MD

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http://dx.doi.org/10.1161/JAHA.115.002640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802489PMC
February 2016

Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study.

J Am Heart Assoc 2016 Feb 29;5(3):e002545. Epub 2016 Feb 29.

National Heart, Lung, and Blood Institute's Division of Intramural Research, The Framingham Heart Study, and the Population Studies Branch, Framingham, MA Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943240PMC
February 2016

Causes of late mortality with dual antiplatelet therapy after coronary stents.

Eur Heart J 2016 Jan 18;37(4):378-85. Epub 2015 Nov 18.

The Christ Hospital Heart and Vascular Center, The Lindner Center for Research and Education, Cincinnati, OH, USA.

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http://dx.doi.org/10.1093/eurheartj/ehv614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751218PMC
January 2016

Benefits and Risks of Extended Dual Antiplatelet Therapy After Everolimus-Eluting Stents.

JACC Cardiovasc Interv 2016 Jan;9(2):138-47

Harvard Medical School, Boston, Massachusetts; Harvard Clinical Research Institute, Boston, Massachusetts; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2015.10.001DOI Listing
January 2016

The MitraClip and survival in patients with mitral regurgitation at high risk for surgery: A propensity-matched comparison.

Am Heart J 2015 Nov 12;170(5):1050-1059.e3. Epub 2015 Aug 12.

Duke Clinical Research Institute, Duke University Medical Center, Durham, NC; Division of Cardiology, Duke University Medical Center, Durham, NC.

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http://dx.doi.org/10.1016/j.ahj.2015.08.004DOI Listing
November 2015

Predicted vs Observed Clinical Event Risk for Cardiovascular Disease-Reply.

JAMA 2015 Nov;314(19):2082-3

Cardiac MR PET CT Program, Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1001/jama.2015.12931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858905PMC
November 2015

Association between visceral and subcutaneous adipose depots and incident cardiovascular disease risk factors.

Circulation 2015 Oct 20;132(17):1639-47. Epub 2015 Aug 20.

From National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (T.M.A., C.S.F.); National Heart, Lung, and Blood Institute, Bethesda, MD (T.M.A., C.S.F.); Department of Endocrinology, Hypertension, and Diabetes, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (T.M.A., A.P., C.S.F.); Department of Biostatistics, Boston University School of Public Health, MA (J.M.M.); and Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston (U.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.015000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779497PMC
October 2015

Hepatic steatosis and cardiovascular disease outcomes: An analysis of the Framingham Heart Study.

J Hepatol 2015 Aug 14;63(2):470-6. Epub 2015 Mar 14.

Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI, United States; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.02.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282653PMC
August 2015

Time to Epinephrine and Survival After Pediatric In-Hospital Cardiac Arrest.

JAMA 2015 Aug;314(8):802-10

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts3Division of Pulmonary and Critical Care Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2015.9678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191294PMC
August 2015

Guideline-Based Statin Eligibility, Coronary Artery Calcification, and Cardiovascular Events.

JAMA 2015 Jul;314(2):134-41

Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston7Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1001/jama.2015.7515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754085PMC
July 2015

Hepatic steatosis is associated with lower levels of physical activity measured via accelerometry.

Obesity (Silver Spring) 2015 Jun 9;23(6):1259-66. Epub 2015 May 9.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.

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http://dx.doi.org/10.1002/oby.21058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446168PMC
June 2015

Autonomic Imbalance as a Predictor of Metabolic Risks, Cardiovascular Disease, Diabetes, and Mortality.

J Clin Endocrinol Metab 2015 Jun;100(6):2443-8

Departments of Psychiatry (L.R.W., JL.P.) and Mathematics (P.S.H.), University of Cincinnati College of Medicine, Cincinnati VA Medical Center, Cincinnati, Ohio 45220; and Department of Biostatistics (J.M.M., R.B.D.), Boston University School of Public Health, and Department of Mathematics and Statistics (R.B.D.), Boston University, Boston, Massachusetts 02215.

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http://dx.doi.org/10.1210/jc.2015-1748DOI Listing
June 2015

Benefits and Risks of Extended Duration Dual Antiplatelet Therapy After PCI in Patients With and Without Acute Myocardial Infarction.

J Am Coll Cardiol 2015 May 15;65(20):2211-21. Epub 2015 Mar 15.

Harvard Clinical Research Institute, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678101PMC
May 2015

Distribution of seizures across the menstrual cycle in women with epilepsy.

Epilepsia 2015 May 30;56(5):e58-62. Epub 2015 Mar 30.

Harvard Clinical Research Institute, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1111/epi.12969DOI Listing
May 2015

Moderate-to-vigorous physical activity with accelerometry is associated with visceral adipose tissue in adults.

J Am Heart Assoc 2015 Mar 3;4(3):e001379. Epub 2015 Mar 3.

National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (J.M.M., A.P., J.M.M., R.S.V., S.J.B., C.S.F.) Division of Intra-mural Research and the Center for Population Studies, National Heart, Lung and Blood Institute, Framingham, MA (C.S.F.) Division of Endocrinology & Harvard Medical School, Brigham and Women's Hospital, Boston, MA (C.S.F.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392428PMC
March 2015

Response to letters regarding article, "A randomized trial of social media from Circulation".

Circulation 2015 Mar;131(13):e396

Circulation Editorial Office, Boston, MADepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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March 2015

A randomized trial of social media from Circulation.

Circulation 2015 Jan 18;131(1):28-33. Epub 2014 Nov 18.

From the Circulation Editorial Offices, Boston MA (C.S.F., M.A.B., J.J.R., J.M.M., K.B., J.L.); Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (M.A.B.); Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City, UT (J.J.R.); Department of Biostatistics, Boston University School of Public Health, Boston, MA (J.M.M.); and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (J.L.).

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January 2015

Long-term risk of cardiovascular events across a spectrum of adverse major plasma lipid combinations in the Framingham Heart Study.

Am Heart J 2014 Dec 16;168(6):878-83.e1. Epub 2014 Sep 16.

Framingham Heart Study, Framingham, MA; Boston University School of Medicine, Boston, MA.

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December 2014

Development and reproducibility of a computed tomography-based measurement for upper body subcutaneous neck fat.

J Am Heart Assoc 2014 Dec;3(6):e000979

Division of Endocrinology and Metabolism, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338686PMC
December 2014